THERAPEUTIC COMPOSITIONS FOR ENHANCED HEALING OF WOUNDS AND SCARS

    公开(公告)号:US20240366828A1

    公开(公告)日:2024-11-07

    申请号:US18254009

    申请日:2023-04-01

    Abstract: The subject invention provides topical therapeutic compositions and methods of their use for enhanced healing of wounds, including burns, and scars of the skin. Specifically, in one embodiment, the subject invention provides materials and methods for reducing the healing time of skin wounds and for reducing the appearance of scars. The subject invention utilizes topical compositions comprising microbial growth by-products and, optionally, a topically-acceptable carrier. In specific embodiments, the microbial growth by-products are biosurfactants.

    Compositions I-I and products and uses thereof

    公开(公告)号:US11938231B2

    公开(公告)日:2024-03-26

    申请号:US17093214

    申请日:2020-11-09

    Abstract: A curable composition apportioned between at least one Part A and at least one Part B, the Parts sealed within barrier means in manner to prevent contamination thereof, the composition comprising:



    (i) one or more alkenyl-containing prepolymers having at least one alkenyl moiety per molecule,
    (ii) one or more SiH-containing prepolymers having at least one SiH unit per molecule, and additionally:
    (iii) a catalyst for curing by addition of alkenyl-containing prepolymer (i) to SiH-containing prepolymer (ii),
    wherein the at least one Part A and at least one Part B are provided within or upon at least two respective receptacles or supports and are adapted to be dispensed or released therefrom in cooperative manner facilitating intimate contact and curing thereof, wherein the receptacle(s) or support(s) for at least one of Part A and Part B is thermally stable at elevated temperature of 123 C for a period in excess of 18 hours,
    methods for preparing the composition, methods for sterilisation thereof, medical and non-medical use thereof, a device incorporating the composition, and a precursor therefor including its sterilisable precursor composition, in particular a terminally sterilisable or terminally sterile composition for medical use, particularly in wound therapy, more particularly as a wound packing material which can be shaped and configured to the shape of a wound, most particularly for application in negative pressure wound therapy (NPWT).

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