Abstract:
The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.
Abstract:
A drive system with harmonic drive designed to meet the high power and torque requirements required to drive an aircraft independently on the ground is provided. The drive system includes an electric motor driven by a harmonic drive assembly that may be configured to be integral with the motor. This drive system with harmonic drive can be effectively installed in an existing aircraft nose wheel or main wheel without changes to other components.
Abstract:
The present invention describes systems and methods for treating disorders and/or conditions associated with the dermal level of the skin. Such disorders include acne, hyperhidrosis, bromhidrosis, chromhidrosis, rosacea, hair loss, dermal infection, and/or actinic keratosis. Methods generally involve administering nanoemulsions (e.g., nanoparticle compositions) comprising at least one therapeutic agent, such as botulinum toxin. In some embodiments, nanoemulsions are prepared, e.g., by high pressure microfluidization, and comprise a particle size distribution exclusively between 10 nm and 300 nm.
Abstract:
The present invention provides nanoparticle compositions including one or more peptides. The present invention achieves transdermal delivery of such peptides without the need for peptide modification, or for use of chemical or mechanical abrasion or disruption of skin.
Abstract:
A system for minimizing damage on collision to a vehicle having at least one self-propelled wheel is disclosed. The system comprises a motor in a wheel of said vehicle which drives the vehicle, means for measuring the speed of said wheel, means for measuring the torque of said motor, means for monitoring the ratio of the torque of the motor to the speed of the wheel, and means for stopping said motor when torque:speed ratio exceeds an acceptable value.
Abstract:
The present invention is a rotating induction motor that is capable of providing higher peak torque than a conventional design, which achieves the shortcomings of the prior art by in regard to iron saturation by a slot-less design; removing the iron slot provides more space for the conductor. The motor comprises a stator and a concentric rotor, separated from the stator by an air gap. The rotor has rotor bars and rotor windings. The stator is slot-less and comprises surface mounted conductors separated from each other by suitable insulation. An advantage of this design is that the motor does not exhibit typical behavior at high currents; there is no saturation effect.
Abstract:
The present invention is a compound planetary gear system which has a moveable sun gear and a lockable sun gear to change the gear ratio between a high gear ratio and a pseudo 1:1 slipping ratio. The system makes use of a ratchet and pawl mechanism to provide a safety backup for when the lockable sun gear is locked. The invention may be used to move the aircraft from a stationary position, for taxiing, and for pre-rotating the wheels prior to landing.
Abstract:
An electrical rotating apparatus is provided that has variable impedance. This is achieved by connecting one of the polyphase components of the apparatus in a mesh connection. The spanning value, L, of such a mesh connection may be varied by changing the harmonic content supplied by an inverter component. Also provided is a method for connecting an inverter to a motor, wherein a switching arrangement permits the simple alteration between various mesh connections of different span value, changing thereby the Volts/Hertz ratio of the motor.
Abstract:
The present invention discloses small compact motor systems which may be located inside a vehicle drive wheel, and which allow a drive motor to provide the necessary torque with reasonable system mass. The motor systems of the invention utilize polyphase electric motors, and are preferably connected to appropriate drive systems via mesh connections, to provide variable V/Hz ratios. In one embodiment the stator coils are wound around the inside and outside of the stator. In a further embodiment, the machine contains a high number of phases, greater than three. In a further embodiment, the phases are connected in a mesh connection. In a further embodiment, each half-phase is independently driven to enable second harmonic drive for an impedance effect. Improvements are apparent in efficiency and packing density.
Abstract:
In a method for operating a blast furnace, the primary supply of reductant and heat is an hydrogen reducing blast. Oxygen or water vapor is injected into the blast furnace to control temperature. Coke is used to provide appropriate gas channels and carburization. Coke use rate can be reduced to less than 10% of that of conventional blast furnace operation. A conventional blast furnace may be converted to this method with minor modification.