公开(公告)号：US11358137B2

公开(公告)日：2022-06-14

申请号：US16726940

申请日：2019-12-26

Applicant: Industrial Technology Research Institute

Inventor： Shaw-Hwa Parng ,  Su-Jan Lee ,  Ping-Jung Wu ,  Ruey-Shyan Hong ,  Yu-Yin Tsai

IPC: B01L3/02 ,  B01L3/00 ,  C12Q1/686 ,  C12Q1/68

Abstract: A tubular structure for producing droplets and a method of using the tubular structure to produce droplets are provided. The tubular structure includes microchannel structures, and is used for droplet generation, droplet collection, nucleic acid amplification and/or in situ droplet detection, etc.

公开(公告)号：US20200261903A1

公开(公告)日：2020-08-20

申请号：US16726940

申请日：2019-12-26

Applicant: Industrial Technology Research Institute

Inventor： Shaw-Hwa Parng ,  Su-Jan Lee ,  Ping-Jung Wu ,  Ruey-Shyan Hong ,  Yu-Yin Tsai

IPC: B01L3/02 ,  B01L3/00 ,  C12Q1/686

Abstract: A tubular structure for producing droplets and a method of using the tubular structure to produce droplets are provided. The tubular structure includes microchannel structures, and is used for droplet generation, droplet collection, nucleic acid amplification and/or in situ droplet detection, etc.

公开(公告)号：US20180164196A1

公开(公告)日：2018-06-14

申请号：US15381116

申请日：2016-12-16

Applicant: Industrial Technology Research Institute

Inventor： Chien-An Chen ,  Wen-Ching Lee ,  Tzu-Hui Wu ,  Pei-Shin Jiang ,  Ping-Jung Wu ,  Ruey-Shyan Hong ,  Hsiao-Jou Chang ,  Chun-Chieh Huang ,  Ting-Hsuan Chen ,  Chih-Lung Lin

IPC: G01N1/36 ,  G01N1/40

CPC classification number: G01N1/36 ,  B01L3/508 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/0605 ,  B01L2200/0621 ,  B01L2200/0631 ,  B01L2300/0681 ,  B01L2300/0832 ,  B01L2300/0867 ,  B01L2400/0478 ,  B01L2400/0622 ,  B01L2400/0644 ,  C12M1/42 ,  C12N15/10 ,  G01N33/48

Abstract: A biological sample processing device includes a base, a purification unit, a metering unit and a first tube. The purification unit is disposed on the base and is configured to purify a sample. The metering unit is disposed on the base and has an inlet, at least one metering trough and an overflow trough. The inlet is connected to the purification unit via the first tube, and the metering trough is connected between the inlet and the overflow trough. The sample from the purification unit is configured to enter the metering unit through the inlet to be moved toward the metering trough, and to be moved toward the overflow trough after the metering trough is filled with the sample.

公开(公告)号：US11884912B2

公开(公告)日：2024-01-30

申请号：US16727057

申请日：2019-12-26

Applicant: Industrial Technology Research Institute

Inventor： Kuo-Hsing Wen ,  Ting-Hsuan Chen ,  Cheng-Tai Chen ,  Chien-An Chen ,  Su-Fung Chiu ,  Yung-Chi Chang ,  Nien-Jen Chou ,  Ping-Jung Wu ,  Shaw-Hwa Parng ,  Pei-Shin Jiang

IPC: C12M1/34 ,  C12M1/00 ,  C12M1/02 ,  C12M1/24

CPC classification number: C12M41/46 ,  C12M23/08 ,  C12M27/00 ,  C12M29/00 ,  C12M41/26

Abstract: A cell culture device includes a culture unit, a gas supply unit, a first pressure unit, at least one inspecting unit and a control unit. The culture unit contains a cell culture liquid. The gas supply unit, connected with the culture unit, is used for transmitting a culture gas into the culture unit. The first pressure unit, connected with the culture unit, is used for applying a pressure to the cell culture liquid in the culture unit. The at least one inspecting unit, connected with the culture unit, is used for receiving the cell culture liquid for inspection. The control unit, electrically coupled with the culture unit, the first pressure unit, the gas supply unit and the at least one inspecting unit, is used for monitoring corresponding condition parameters to determine respective operations. In addition, a cell culture method for the cell culture device is also provided.

公开(公告)号：US20230201840A1

公开(公告)日：2023-06-29

申请号：US17564243

申请日：2021-12-29

Applicant: Industrial Technology Research Institute

Inventor： Chun-Chuan Lin ,  Hsiao-Yue Tsao ,  Shih-Bin Luo ,  Kuo-Hsing Wen ,  Chien-Chih Kuo ,  Ping-Jung Wu ,  Ruey-Shyan Hong ,  Ting-Hsuan Chen

IPC: B01L7/00 ,  G01N21/64 ,  B01L9/00

CPC classification number: B01L7/52 ,  G01N21/6486 ,  B01L9/527 ,  G01N2021/6419 ,  G01N2021/6421 ,  C12Q1/686

Abstract: A convective polymerase chain reaction apparatus and an optical detecting method thereof are provided. The optical detecting method includes the following steps. A substance in a tube to be tested is heated. At least two monochromatic lights are provided and are combined using a light combining element to irradiate the tube to be tested. At least two excited lights generated by exciting the substance in the tube to be tested by the at least two monochromatic lights are sensed.

公开(公告)号：US09505003B2

公开(公告)日：2016-11-29

申请号：US14582697

申请日：2014-12-24

Applicant: Industrial Technology Research Institute

Inventor： Chih-Hsiang Sung ,  Tseng-Huang Liu ,  Ruey-Shyan Hong ,  Ting-Hsuan Chen ,  Ping-Jung Wu ,  Kuo-Hsing Wen ,  Wan-Chi Chang

IPC: B01L7/00 ,  C12M1/38 ,  B01L9/06

CPC classification number: B01L7/52 ,  B01L9/06 ,  B01L2200/18 ,  B01L2300/046 ,  B01L2300/0663 ,  B01L2300/1805 ,  B01L2300/1844

Abstract: A portable real-time heating and detection device includes a body, a cover and a detection unit. The body has an opening, and a base. The cover has a control unit and a fix unit. The detection unit is disposed on the base of the body and has a thermostat, an optical excitation, an optical detection, and a circuit board. The thermostat is disposed close to the opening and has at least one thermostat zone. The optical exciter is disposed between the thermostat and the base. The optical detector is disposed between the thermostat and the opening. The circuit board is electrical coupled to the control unit, the thermostat, the optical excitation, and the optical detector, respectively.

Abstract translation: 便携式实时加热和检测装置包括主体，盖和检测单元。 身体有一个开口和一个基地。 盖具有控制单元和固定单元。 检测单元设置在主体的基座上并具有恒温器，光学激励，光学检测和电路板。 恒温器靠近开口设置，并具有至少一个恒温区。 光激发器设置在恒温器和基座之间。 光学检测器设置在恒温器和开口之间。 电路板分别电耦合到控制单元，恒温器，光学激励和光学检测器。