公开(公告)号：US20190265457A1

公开(公告)日：2019-08-29

申请号：US16407093

申请日：2019-05-08

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio IWASE ,  Masatoshi OKUGAWA

IPC: G02B21/36 ,  H04N5/232 ,  G02B7/36 ,  G02B21/02 ,  G02B21/26 ,  G02B21/24

Abstract: In an image acquisition device, an optical path difference generating member can form an optical path length difference of a second optical image without splitting light in a second optical path. This can suppress the quantity of light required for the second optical path to obtain information of the focal position, whereby a quantity of light can be secured for a first imaging device to capture an image. The image acquisition device synchronizes the movement of a predetermined part of a sample within a field of an objective lens with rolling readout such that each pixel column of a second imaging device is exposed to an optical image of the predetermined part in the sample.

公开(公告)号：US20160156832A1

公开(公告)日：2016-06-02

申请号：US14786574

申请日：2014-03-07

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Hideshi OISHI ,  Fumio IWASE ,  Masatoshi OKUGAWA

IPC: H04N5/232 ,  H04N5/262 ,  G02B21/24 ,  G02B7/36 ,  G02B21/18 ,  G02B21/36 ,  H04N5/247 ,  H04N5/235

CPC classification number: H04N5/23212 ,  G02B7/346 ,  G02B7/36 ,  G02B7/365 ,  G02B21/18 ,  G02B21/244 ,  G02B21/245 ,  G02B21/361 ,  G02B21/365 ,  G02B21/367 ,  H04N5/2351 ,  H04N5/2353 ,  H04N5/247 ,  H04N5/2628

Abstract: In an image acquisition device, an optical path difference generating member can form an optical path length difference of a second light image without splitting light in a second optical path. This can suppress the quantity of light required for the second optical path to obtain information of the focal position, whereby a quantity of light can be secured for a first imaging device to capture an image. The image acquisition device synchronizes the movement of a predetermined part of a sample within a field of an objective lens with rolling readout such that each pixel column of a second imaging device is exposed to a light image of the predetermined part in the sample.

Abstract translation: 在图像获取装置中，光路差产生部件可以在第二光路中不分裂光而形成第二光图像的光路长度差。 这可以抑制第二光路所需的光量以获得焦点位置的信息，从而可以确保第一成像装置的光量以捕获图像。 图像采集装置使物镜的场中的样本的预定部分的移动与滚动读出同步，使得第二成像装置的每个像素列暴露于样品中的预定部分的光图像。

公开(公告)号：US20160252717A1

公开(公告)日：2016-09-01

申请号：US15030198

申请日：2014-01-28

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio IWASE

IPC: G02B21/36 ,  G02B21/06 ,  G02B21/24 ,  G06T5/00

Abstract: In an image acquisition device, imaging is performed using an imaging element capable of rolling reading an optical image of a sample irradiated with instantaneous light. Therefore, the image can be captured with a sufficient S/N ratio even when the optical image is weak. Further, the image acquisition device includes a light source control unit that causes the instantaneous light to be emitted from a light source from the start of exposure of a pixel row of which reading last starts to the start of reading of a pixel row of which the reading first starts. That is, in the image acquisition device, the light source control unit causes the sample to be irradiated with the instantaneous light from the light emitting means during a period of time in which all pixel rows of the imaging element are exposed.

Abstract translation: 在图像获取装置中，使用能够滚动读取用瞬时光照射的样本的光学图像的成像元件来进行成像。 因此，即使光学图像较弱，也可以以足够的S / N比拍摄图像。 此外，图像获取装置包括光源控制单元，其使得从开始的读取开始的开始到开始读取的像素行的开始从光源发射瞬时光，其中， 阅读第一次开始。 也就是说，在图像获取装置中，光源控制单元使得在所有成像元件的所有像​​素行都暴露的时间段期间，来自发光装置的瞬时光照射样本。

公开(公告)号：US20130112853A1

公开(公告)日：2013-05-09

申请号：US13666098

申请日：2012-11-01

Applicant: Hamamatsu Photonics K.K.

Inventor： Motohiro SUYAMA ,  Akiomi UJIMA ,  Kentaro MAETA ,  Hisanori SUZUKI ,  Masaharu MURAMATSU ,  Fumio IWASE

IPC: H01L27/148

CPC classification number: H01L27/14843 ,  H04N3/1525 ,  H04N3/1537 ,  H04N5/3722

Abstract: A solid-state imaging device 1A includes a CCD-type solid-state imaging element 10 having an imaging plane 12 formed of M×N pixels that are two-dimensionally arrayed in M rows and N columns, N signal readout circuits 20 arranged on one end side in the column direction for each of the columns with respect to the imaging plane 12, and N signal readout circuits 30 arranged on the other end side in the column direction for each of the columns with respect to the imaging plane 12, a semiconductor element 50 for digital-converting and then sequentially outputting as serial signals electrical signals output from the signal readout circuits 20 for each of the columns, and a semiconductor element 60 for digital-converting and then sequentially outputting as serial signals electrical signals output from the signal readout circuits 30 for each of the columns.

Abstract translation: 固态成像装置1A包括CCD型固体摄像元件10，其具有由M×N个像素形成的成像面12，二维排列成M行N列，N个信号读出电路20配置在一个 相对于成像面12的各列的列方向的端侧，以及相对于摄像面12对于列的列方向配置在另一端侧的N个信号读出电路30，半导体 元件50，用于数字转换，然后顺序地输出作为串行信号从每个列的信号读出电路20输出的电信号;以及半导体元件60，用于数字转换，然后顺序地输出作为串行信号从信号输出的电信号 每列的读出电路30。

公开(公告)号：US20160267317A1

公开(公告)日：2016-09-15

申请号：US15031083

申请日：2014-01-28

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio IWASE

IPC: G06K9/00 ,  G02B21/06 ,  G02B21/26 ,  G02B21/36

CPC classification number: G06K9/00134 ,  G02B21/06 ,  G02B21/086 ,  G02B21/26 ,  G02B21/365 ,  G02B21/367 ,  H04N5/23238

Abstract: In this image acquisition device, a stage driving unit moves a position of a field of view of an objective lens relative to a sample at a predetermined velocity, and a two-dimensional imaging element sequentially captures an optical image of the sample at a predetermined frame rate. Therefore, time required for acquiring partial images over the entire sample is shortened. Further, in this image acquisition device, the moving velocity of the position of the field of view is a velocity set based on a frame rate of the imaging element. Therefore, the movement of the position of the field of view and the imaging of the imaging element are synchronized with each other, and it is possible to capture only necessary partial images.

Abstract translation: 在该图像采集装置中，台驱动单元以预定的速度移动物镜相对于样本的视场的位置，二维摄像元件以规定的帧顺序捕获样本的光学图像 率。 因此，缩短了在整个样本上获取部分图像所需的时间。 此外，在该图像获取装置中，视场的位置的移动速度是基于摄像元件的帧速度设定的速度。 因此，视场的位置和成像元件的成像的移动彼此同步，并且可以仅捕获必需的部分图像。

公开(公告)号：US20160077322A1

公开(公告)日：2016-03-17

申请号：US14786576

申请日：2014-04-21

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio IWASE ,  Masatoshi OKUGAWA

IPC: G02B21/36 ,  G02B21/02 ,  G02B21/26 ,  H04N5/232

CPC classification number: G02B21/365 ,  G02B7/36 ,  G02B21/02 ,  G02B21/244 ,  G02B21/26 ,  G02B21/361 ,  G02B21/367 ,  H04N5/23212

Abstract: In an image acquisition device, an optical path difference generating member can form an optical path length difference of a second optical image without splitting light in a second optical path. This can suppress the quantity of light required for the second optical path to obtain information of the focal position, whereby a quantity of light can be secured for a first imaging device to capture an image. The image acquisition device synchronizes the movement of a predetermined part of a sample within a field of an objective lens with rolling readout such that each pixel column of a second imaging device is exposed to an optical image of the predetermined part in the sample.

Abstract translation: 在图像获取装置中，光路差产生部件可以在第二光路中不分裂光而形成第二光学图像的光程差。 这可以抑制第二光路所需的光量以获得焦点位置的信息，从而可以确保第一成像装置的光量以捕获图像。 图像采集装置使物镜的场中的样本的预定部分的移动与滚动读出同步，使得第二成像装置的每个像素列暴露于样品中的预定部分的光学图像。

公开(公告)号：US20130107097A1

公开(公告)日：2013-05-02

申请号：US13666149

申请日：2012-11-01

Applicant: Hamamatsu Photonics K.K.

Inventor： Motohiro SUYAMA ,  Akiomi UJIMA ,  Kentaro MAETA ,  Hisanori SUZUKI ,  Masaharu MURAMATSU ,  Fumio IWASE

IPC: H04N5/335

CPC classification number: H01L27/14618 ,  H01L2224/16 ,  H01L2224/48091 ,  H04N5/2253 ,  H01L2924/00014

Abstract: A solid-state imaging device 2A includes a CCD-type solid-state imaging element 10 having an imaging plane 12 formed of M×N pixels that are two-dimensionally arrayed in M rows and N columns and N signal readout circuits 20 arranged on one end side in the column direction for each of the columns with respect to the plane 12 and for outputting electrical signals according to the magnitudes of charges taken out of the respective columns, respectively, a C-MOS-type semiconductor element 50 for digital-converting and sequentially outputting as serial signals electrical signals output from the circuits 20 for each of the columns, a heat transfer member 80 having a main surface 81a and a back surface 81b, and a cooling block 84 provided on the surface 81b, and the semiconductor element 50 and the surface 81a of the heat transfer member 80 are bonded to each other.

Abstract translation: 固态成像装置2A包括CCD型固体摄像元件10，该CCD型固体摄像元件10具有由M×N像素构成的摄像面12，二维排列成M行N列，N信号读出电路20配置在一方 用于每个列相对于平面12的列方向的端侧，并分别根据从各列取出的电荷的大小输出电信号，用于数字转换的C-MOS型半导体元件 并顺序地输出作为串行信号从每个列的电路20输出的电信号，具有主表面81a和后表面81b的传热构件80和设置在表面81b上的冷却块84，以及半导体元件 50和传热构件80的表面81a彼此接合。