公开(公告)号：US20060229352A1

公开(公告)日：2006-10-12

申请号：US11399142

申请日：2006-04-06

申请人： Gerardus Kemperman ,  Jacobus Van Der Linden ,  Michael Reeder

发明人： Gerardus Kemperman ,  Jacobus Van Der Linden ,  Michael Reeder

IPC分类号： A61K31/407 ,  C07D491/02 ,  C07D323/00 ,  A61K31/335

CPC分类号： C07D313/14 ,  C07D491/04

摘要： Disclosed are novel amino acid derivatives of formula (I) and (II) processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.

摘要翻译： 公开了式（I）和（II）的新型氨基酸衍生物及其制备方法及其在制备反式-5-氯-2-甲基-2,3,3a，12b-四氢-1H- 二苯并[2,3：6,7]氧杂环庚烯并[4,5-c]吡咯。

公开(公告)号：US20070105921A1

公开(公告)日：2007-05-10

申请号：US11538155

申请日：2006-10-03

申请人： Michael Reeder ,  Rick Imbordino

发明人： Michael Reeder ,  Rick Imbordino

IPC分类号： A61K31/422 ,  A61K31/421 ,  C07D263/02

CPC分类号： C07D263/32

摘要： Disclosed are compounds of formula III and a process to prepare a compound of formula III wherein R1, R2, R3 and R6 are defined herein, using a zinc chloride/optionally substituted oxazole adduct and an compound of formula I. Further disclosed are methods of using compounds of formula III to prepare compounds useful in the treatment of Alzheimer's disease and related conditions.

摘要翻译： 公开了式III的化合物及其制备式III化合物的方法，其中R 1，R 2，R 3和R 3 在本文中定义，使用氯化锌/任选取代的恶唑加合物和式I化合物。进一步公开了使用式III化合物来制备可用于治疗阿尔茨海默病和相关病症的化合物的方法。

公开(公告)号：US20080027101A1

公开(公告)日：2008-01-31

申请号：US11775383

申请日：2007-07-10

申请人： Pauline Ting ,  Joe Lee ,  Kung-I Feng ,  Michael Reeder ,  Scott Trzaska ,  Man Zhu ,  Chen Mao ,  Dimitar Filipov ,  Dimitrios Zarkadas

发明人： Pauline Ting ,  Joe Lee ,  Kung-I Feng ,  Michael Reeder ,  Scott Trzaska ,  Man Zhu ,  Chen Mao ,  Dimitar Filipov ,  Dimitrios Zarkadas

IPC分类号： A61K31/47 ,  A61P11/06 ,  C07D215/00

CPC分类号： C07D413/14

摘要： The present invention relates to the compound of the formula To methods of treating upper and lower obstructive airway diseases using said compound, to formulations comprising it, and to polymorphs and processes of synthesis of the polymorphic forms.

摘要翻译： 本发明涉及式的化合物：使用所述化合物，包含它的制剂治疗上下阻塞性气道疾病的方法以及多晶型物和多晶型物合成方法。

公开(公告)号：US20050130936A1

公开(公告)日：2005-06-16

申请号：US11048389

申请日：2005-02-01

申请人： Michael Reeder

发明人： Michael Reeder

IPC分类号： C07D301/28 ,  C07B61/00 ,  C07C213/02 ,  C07C215/28 ,  C07C217/82 ,  C07C229/36 ,  C07C233/78 ,  C07C269/06 ,  C07C271/16 ,  C07C271/18 ,  C07C271/20 ,  C07C271/22 ,  C07D301/26 ,  C07D301/27 ,  C07D303/36 ,  A61K31/695 ,  A61K31/138 ,  A61K31/277

CPC分类号： C07D303/36 ,  C07D301/26

摘要： Disclosed are intermediates and processes for preparing epoxides of the formula: where R and PROT are defined herein. These epoxides are useful as intermediates in the production of biologically active compounds, i.e., in the production of pharmaceutical agents.

摘要翻译： 公开了用于制备下式的环氧化物的中间体和方法：其中R和PROT在本文中定义。 这些环氧化物可用作生物活性化合物的生产中的中间体，即在制药中。

公开(公告)号：US20080045718A1

公开(公告)日：2008-02-21

申请号：US11891348

申请日：2007-08-10

申请人： Timothy Cutarelli ,  Xiaoyong Fu ,  Timothy McAllister ,  Michael Reeder ,  Jianguo Yin ,  Kelvin Yong ,  Shuyi Zhang

发明人： Timothy Cutarelli ,  Xiaoyong Fu ,  Timothy McAllister ,  Michael Reeder ,  Jianguo Yin ,  Kelvin Yong ,  Shuyi Zhang

IPC分类号： C07D401/04 ,  C07C69/34 ,  C07D401/14 ,  C07C69/76

CPC分类号： C07D413/04 ,  C07C271/22 ,  C07D413/14

摘要： This application discloses a novel process to synthesize 2-(Quinolin-5yo)-4,5-Disubstituted-Azole derivatives, which may be used, for example, as PDE IV inhibitor compounds in pharmaceutical preparations.

摘要翻译： 本申请公开了一种合成2-（喹啉-5-基）-4,5-二取代 - 唑衍生物的新方法，其可用作药物制剂中的PDE IV抑制剂化合物。

公开(公告)号：US20060090410A1

公开(公告)日：2006-05-04

申请号：US11296962

申请日：2005-12-07

申请人： Steven Reeder ,  Michael Reeder

发明人： Steven Reeder ,  Michael Reeder

IPC分类号： E06B3/964

CPC分类号： E06B3/6604 ,  B05D3/0254 ,  B32B37/16 ,  E06B1/006 ,  E06B7/00 ,  Y10T29/49623

摘要： A non-metal window muntin formed from plastic or wood is described for use in hermetically sealed insulated glass windows. The process for forming the muntin includes machining polystyrene sheets which are painted with a latex pain and baked prior to use between sealed glass of the window.

公开(公告)号：US11640604B2

公开(公告)日：2023-05-02

申请号：US17772146

申请日：2021-12-10

申请人： Jesse Thomas Seaver ,  Sacha Tueni ,  Noah Thorp ,  Michael Reeder

发明人： Jesse Thomas Seaver ,  Sacha Tueni ,  Noah Thorp ,  Michael Reeder

IPC分类号： G06Q20/38 ,  G06Q20/40 ,  H04L9/00 ,  G06K7/14 ,  G06Q20/36 ,  H04L9/32 ,  G06Q20/06

摘要： A method for performing a transfer using a blockchain network and a uniform resource locator (URL) includes receiving, by computer program code which is stored on the blockchain network, an address on the blockchain network and tokens or value associated therewith the address for writing a blockchain transaction. The URL is associated with the address and includes key parameters thereof. The computer program code receives, as an automated result of execution of the URL, a cryptographically signed transaction having the key parameters of the address and key parameters of a new address that were generated by the execution of the URL. The computer program code transfers, based on the blockchain network reaching consensus on the transaction, at least part of the tokens or value from the address to the new address as a further automated result of the execution of the URL.

公开(公告)号：US20220351198A1

公开(公告)日：2022-11-03

申请号：US17772146

申请日：2021-12-10

申请人： Jesse Thomas Seaver ,  Sacha Tueni ,  Noah Thorp ,  Michael Reeder

发明人： Jesse Thomas Seaver ,  Sacha Tueni ,  Noah Thorp ,  Michael Reeder

IPC分类号： G06Q20/38 ,  H04L9/00 ,  G06Q20/40

摘要： A method for performing a transfer using a blockchain network and a uniform resource locator (URL) includes receiving, by computer program code which is stored on the blockchain network, an address on the blockchain network and tokens or value associated therewith the address for writing a blockchain transaction. The URL is associated with the address and includes key parameters thereof. The computer program code receives, as an automated result of execution of the URL, a cryptographically signed transaction having the key parameters of the address and key parameters of a new address that were generated by the execution of the URL. The computer program code transfers, based on the blockchain network reaching consensus on the transaction, at least part of the tokens or value from the address to the new address as a further automated result of the execution of the URL.

公开(公告)号：US20080060317A1

公开(公告)日：2008-03-13

申请号：US11981400

申请日：2007-10-31

申请人： Steven Reeder ,  Michael Reeder

发明人： Steven Reeder ,  Michael Reeder

IPC分类号： E06B5/00 ,  E06B7/00

CPC分类号： E06B3/6604 ,  B05D3/0254 ,  B32B37/16 ,  E06B1/006 ,  E06B7/00 ,  Y10T29/49623

摘要： A non-metal window muntin formed from plastic or wood is described for use in hermetically sealed insulated glass windows. The process for forming the muntin includes machining polystyrene sheets which are painted with a latex pain and baked prior to use between sealed glass of the window.