公开(公告)号：US20240285704A1

公开(公告)日：2024-08-29

申请号：US18406671

申请日：2024-01-08

申请人： FP Nutraceuticals, LLC

发明人： Timothy M. Marshall

IPC分类号： A61K36/185 ,  A23L33/105 ,  A23L33/115 ,  A23L33/125 ,  A23L33/155 ,  A23L33/16 ,  A23L33/165 ,  A23L33/175 ,  A61K9/00 ,  A61K31/015 ,  A61K31/05 ,  A61K31/07 ,  A61K31/122 ,  A61K31/145 ,  A61K31/16 ,  A61K31/192 ,  A61K31/194 ,  A61K31/198 ,  A61K31/232 ,  A61K31/28 ,  A61K31/30 ,  A61K31/315 ,  A61K31/355 ,  A61K31/375 ,  A61K31/385 ,  A61K31/4188 ,  A61K31/455 ,  A61K31/51 ,  A61K31/525 ,  A61K31/592 ,  A61K31/593 ,  A61K31/675 ,  A61K31/69 ,  A61K31/714 ,  A61K33/06 ,  A61K33/18 ,  A61K36/03 ,  A61K36/42 ,  A61K36/45

CPC分类号： A61K36/185 ,  A23L33/105 ,  A23L33/115 ,  A23L33/125 ,  A23L33/155 ,  A23L33/16 ,  A23L33/165 ,  A23L33/175 ,  A61K9/0056 ,  A61K31/015 ,  A61K31/05 ,  A61K31/07 ,  A61K31/122 ,  A61K31/145 ,  A61K31/16 ,  A61K31/192 ,  A61K31/194 ,  A61K31/198 ,  A61K31/232 ,  A61K31/28 ,  A61K31/30 ,  A61K31/315 ,  A61K31/355 ,  A61K31/375 ,  A61K31/385 ,  A61K31/4188 ,  A61K31/455 ,  A61K31/51 ,  A61K31/525 ,  A61K31/592 ,  A61K31/593 ,  A61K31/675 ,  A61K31/69 ,  A61K31/714 ,  A61K33/06 ,  A61K33/18 ,  A61K36/03 ,  A61K36/42 ,  A61K36/45 ,  A23V2002/00

摘要： The compositions of this disclosure provide broad-spectrum nutrient supplementation to support the health of multiple organ and tissue systems in which mitochondrial function plays a fundamental role. In particular, the formulations promote neuroprotective, cardioprotective, immunosupportive, and anti-aging benefits. Also provided herein are novel, neuroprotective preparations containing a combination of broad- or full-spectrum hemp oil extract combined with niacinamide, a non-flushing form of vitamin B3, and methods of use are described allowing for safe, effective, and convenient use of a neuroprotective, antioxidant preparation for general and clinical use.

公开(公告)号：US20240115493A1

公开(公告)日：2024-04-11

申请号：US18545415

申请日：2023-12-19

申请人： FP Nutraceuticals, LLC

发明人： Timothy M. Marshall

IPC分类号： A61K9/00 ,  A61K9/16 ,  A61K9/28 ,  A61K9/70 ,  A61K31/135 ,  A61K31/167 ,  A61K31/192 ,  A61K31/194 ,  A61K31/375 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4545 ,  A61K31/485 ,  A61K31/495 ,  A61K31/616 ,  A61K33/00 ,  A61K33/04 ,  A61K33/06 ,  A61K33/30 ,  A61K45/06 ,  A61K47/02 ,  A61K47/12 ,  A61K47/14 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A61K47/44 ,  A61K47/69

CPC分类号： A61K9/006 ,  A61K9/0056 ,  A61K9/1652 ,  A61K9/2826 ,  A61K9/2886 ,  A61K9/7007 ,  A61K31/135 ,  A61K31/167 ,  A61K31/192 ,  A61K31/194 ,  A61K31/375 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4545 ,  A61K31/485 ,  A61K31/495 ,  A61K31/616 ,  A61K33/00 ,  A61K33/04 ,  A61K33/06 ,  A61K33/30 ,  A61K45/06 ,  A61K47/02 ,  A61K47/12 ,  A61K47/14 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A61K47/44 ,  A61K47/6903

摘要： The oral cavity is an ideal-site for small molecule, nutrient/nutraceutical delivery to the central nervous system (CNS) and systemic circulation due to the highly-vascularized, oral mucosa, near-neutral pH conditions, close proximity to the brain, and avoidance of gastric degradation and the first-pass effect. The rich-blood supply of the oral mucosa and “sticky”, mucoadhesive properties of this novel, saccharide-based, delivery system allows for the efficient absorption of small molecules across several highly-vascularized surfaces including the gingival, sublingual, soft-palatal, and buccal mucosa. Herein, I introduce a novel, saccharide-based, food-form, palatable, easy-to-administer, oral delivery system that attaches to these four, highly-absorptive surfaces for a longer contact-duration than current orally-available formulas resulting in greater, small molecule bioavailability, and a more rapid, therapeutic effect. This invention represents the next-generation in optimized, highly-efficacious, small molecule delivery systems for CNS-related conditions that moves one-step closer in approximating intravenous injection in systemic bioavailability and therapeutic onset.

公开(公告)号：US11229667B2

公开(公告)日：2022-01-25

申请号：US16471519

申请日：2019-02-18

申请人： FP Nutraceuticals, LLC

发明人： Timothy M. Marshall

IPC分类号： A61K33/06 ,  A61K33/00 ,  A61K45/06 ,  A61K9/00

摘要： Neuroprotective preparations (formulations) employing the synergistic, neurotrophic benefits of nutritional lithium with bioavailable magnesium (FIG. 1). The biological synergism of lithium and magnesium is further enhanced with a proprietary base of synergistic, neurotrophic nutrients. A highly-effective, trans-mucosal, delivery system is included to provide exceptional bioavailability of a palatable, convenient intra-oral preparation, which saturates the vascular tissue in the oral cavity for efficient absorption. Additionally, methods of use are described, allowing for effective, safe, and convenient use of this novel, neuroprotective, antioxidant, anti-inflammatory preparation for humans and animals.