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公开(公告)号：US20230392105A1
公开(公告)日：2023-12-07
申请号：US18032042
申请日：2021-10-27
Applicant: CORNING INCORPORATED
Inventor： Stephen Joseph Caracci
CPC classification number: C12M29/26 , C12M23/28 , C12M23/24 , C12M23/34 , C12M29/06 , C12M29/10 , C12M41/12 , C12M41/46
Abstract: A cell culture system is provided that includes a cell culture vessel enclosing an interior configured to culture cells in liquid cell culture media, the cell culture vessel comprising a bioreactor inlet for supply of cell culture media to the interior and a bioreactor outlet for removal of cell culture media from the interior; and a media conditioning system comprising an enclosure enclosing an interior space and a gas exchange system, the gas exchange system comprising a media vessel, wherein the media vessel comprises at least one media cavity configured to contain cell culture media and a gas permeable membrane separating the media cavity from the interior space.
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公开(公告)号：US20240148002A1
公开(公告)日：2024-05-09
申请号：US18280414
申请日：2022-03-07
Applicant: CORNING INCORPORATED
Inventor： Bavani Balakrisnan , Stephen Joseph Caracci , David Michael Fasano , Joseph Martin Rokowski
IPC: A01N59/20 , A01N25/12 , A01N33/20 , A01N43/76 , A01N43/80 , C09D5/14 , C09D7/61 , C09D7/63 , C08K3/40 , C08K5/32 , C08K5/353 , C08K5/47 , C08K13/02
CPC classification number: A01N59/20 , A01N25/12 , A01N33/20 , A01N43/76 , A01N43/80 , C09D5/14 , C09D7/61 , C09D7/63 , C08K3/40 , C08K5/32 , C08K5/353 , C08K5/47 , C08K13/02
Abstract: A biocidal material includes a carrier, a plurality of copper-containing glass particles, and at least one co-biocide selected from isothiazolinones, bicyclic oxazolidines, and bromine nitrogen-based compounds. A minimum bactericidal concentration (MBC) of a combination of the at least one co-biocide and the plurality of copper-containing glass particles is less than an MBC of the at least one co-biocide in the absence of the plurality of copper-containing glass particles.
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公开(公告)号：US11718824B2
公开(公告)日：2023-08-08
申请号：US17332461
申请日：2021-05-27
Applicant: Corning Incorporated
Inventor： Stephen Joseph Caracci , David Henry , Jessica Jo Kelley , Mark Alan Lewis , Yue Zhou
IPC: C12N5/00 , C12N5/0735 , C12N5/0775 , C12M1/00 , B05D3/02
CPC classification number: C12N5/0068 , B05D3/0254 , C12M23/20 , C12N5/0037 , C12N5/0056 , C12N5/0606 , C12N5/0663 , C12N2500/90 , C12N2500/98 , C12N2533/30 , C12N2533/40 , C12N2533/50
Abstract: An aqueous cell culture medium composition includes an aqueous cell culture solution configured to support the culture of mammalian cells. The composition further includes a synthetic polymer conjugated to a polypeptide dissolved in the aqueous cell culture solution. The synthetic polymer conjugated to a polypeptide is configured to attach to the surface of a cell culture article under cell culture conditions. Incubation of the aqueous cell culture medium composition on a cell culture surface under cell culture conditions results is attachment to the surface of the synthetic polymer conjugated to the polypeptide.
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公开(公告)号：US20240352776A1
公开(公告)日：2024-10-24
申请号：US18642102
申请日：2024-04-22
Applicant: CORNING INCORPORATED
Inventor： Julia Madeline Allen , Thomas Bertin-Mourot , Stephen Joseph Caracci
CPC classification number: E05D15/0643 , E05Y2800/122 , E06B2009/2464
Abstract: A slidable pane system includes a slidable pane, at least one track, and a conductor. The slidable pane has an electrically adjustable optical characteristic in response to at least one signal. The at least one track defines the sliding path of the slidable pane. The conductor has an adjustable length along the sliding path of the slidable pane and is electrically coupled to the slidable pane to bridge at least one of the at least one signal or power to the slidable pane.
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公开(公告)号：US20210284957A1
公开(公告)日：2021-09-16
申请号：US17332461
申请日：2021-05-27
Applicant: Corning Incorporated
Inventor： Stephen Joseph Caracci , David Henry , Jessica Jo Kelley , Mark Alan Lewis , Yue Zhou
IPC: C12N5/00 , C12N5/0735 , C12N5/0775 , C12M1/00 , B05D3/02
Abstract: An aqueous cell culture medium composition includes an aqueous cell culture solution configured to support the culture of mammalian cells. The composition further includes a synthetic polymer conjugated to a polypeptide dissolved in the aqueous cell culture solution. The synthetic polymer conjugated to a polypeptide is configured to attach to the surface of a cell culture article under cell culture conditions. Incubation of the aqueous cell culture medium composition on a cell culture surface under cell culture conditions results is attachment to the surface of the synthetic polymer conjugated to the polypeptide.
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Patent Agency Ranking
公开(公告)号：US20240081336A1
公开(公告)日：2024-03-14
申请号：US17642087
申请日：2020-09-09
Applicant: Corning Incorporated
Inventor： Bavani Balakrisnan , Stephen Joseph Caracci , David Michael Fasano , Joydeep Lahiri , Joseph Martin Rokowski
Abstract: A biocidal material and method of forming is provided. The biocidal material includes a carrier and a plurality of treated copper-containing particles including a particle surface pre-treatment. The surface pre-treatment includes a copper-chelating material.
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公开(公告)号：US20240002771A1
公开(公告)日：2024-01-04
申请号：US18039365
申请日：2021-11-19
Applicant: CORNING INCORPORATED
Inventor： Stephen Joseph Caracci , Joel Andrew Schultes
Abstract: A media conditioning vessel is provided for a perfusion bioreactor system. The media conditioning vessel includes a vessel having an interior cavity to hold a volume of liquid cell culture media; a media inlet to return cell culture media from a perfusion bioreactor to the vessel; and a media outlet to transfer cell culture media out of the vessel to the perfusion bioreactor. Sensors to measure or detect a characteristic of the cell culture media are provided in the form of inline sensors in at least one of the media inlet and the media outlet or patch sensors attached to a sidewall or bottom of the media conditioning vessel.
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公开(公告)号：US11667906B2
公开(公告)日：2023-06-06
申请号：US14950771
申请日：2015-11-24
Applicant: Corning Incorporated
Inventor： Stephen Joseph Caracci , Ye Fang , Ann MeeJin Ferrie , Yan Jin , Lingyan Wang , Yue Zhou
Abstract: Magnetic microcarrier beads have a particle size of 1 to 1000 micrometers and include a composite core and a polymer coating that surrounds and encapsulates the core. The composite core includes magnetic particles embedded within an indigestible polymer matrix. The coating is a digestible or indigestible polymer that facilitates cell adhesion to the surface of the beads during cell culture. Magnetic force can be used to agitate the microcarrier beads during cell culture as well as to separate the beads from cultured cells or processed bio-media.
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公开(公告)号：US11046931B2
公开(公告)日：2021-06-29
申请号：US16371252
申请日：2019-04-01
Applicant: Corning Incorporated
Inventor： Stephen Joseph Caracci , David Henry , Jessica Jo Kelley , Mark Alan Lewis , Yue Zhou
IPC: C12N5/00 , C12N5/0735 , B65D3/02 , C12M1/00 , C12N5/0775 , B05D3/02
Abstract: An aqueous cell culture medium composition includes an aqueous cell culture solution configured to support the culture of mammalian cells. The composition further includes a synthetic polymer conjugated to a polypeptide dissolved in the aqueous cell culture solution. The synthetic polymer conjugated to a polypeptide is configured to attach to the surface of a cell culture article under cell culture conditions. Incubation of the aqueous cell culture medium composition on a cell culture surface under cell culture conditions results is attachment to the surface of the synthetic polymer conjugated to the polypeptide.
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公开(公告)号：US10400210B2
公开(公告)日：2019-09-03
申请号：US14375614
申请日：2013-01-31
Applicant: CORNING INCORPORATED
Inventor： Stephen Joseph Caracci , David Henry , Jessica Jo Kelley , Mark Alan Lewis , Yue Zhou
IPC: C12N5/00 , C12N5/0735 , C12N5/0775 , B05D3/02 , C12M1/00
Abstract: An aqueous cell culture medium composition includes an aqueous cell culture solution configured to support the culture of mammalian cells. The composition further includes a synthetic polymer conjugated to a polypeptide dissolved in the aqueous cell culture solution. The synthetic polymer conjugated to a polypeptide is configured to attach to the surface of a cell culture article under cell culture conditions. Incubation of the aqueous cell culture medium composition on a cell culture surface under cell culture conditions results is attachment to the surface of the synthetic polymer conjugated to the polypeptide.
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