公开(公告)号：US10689638B2

公开(公告)日：2020-06-23

申请号：US16700864

申请日：2019-12-02

Applicant: Battelle Energy Alliance, LLC

Inventor： Vicki S. Thompson ,  William A. Apel ,  Jeffrey A. Lacey ,  Brady D. Lee ,  David W. Reed ,  Francisco F. Roberto ,  David N. Thompson

IPC: C12N9/88 ,  C12N15/74 ,  C12N9/00 ,  C12N9/10 ,  C12N15/75

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.

公开(公告)号：US20190127723A1

公开(公告)日：2019-05-02

申请号：US16240411

申请日：2019-01-04

Applicant: Battelle Energy Alliance, LLC

Inventor： Vicki S. Thompson ,  William A. Apel ,  Jeffrey A. Lacey ,  Brady D. Lee ,  David W. Reed ,  Francisco F. Roberto ,  David N. Thompson

IPC: C12N9/88 ,  C12N15/74 ,  C12N9/00 ,  C12N15/75 ,  C12N9/10

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.

公开(公告)号：US10240177B2

公开(公告)日：2019-03-26

申请号：US15898378

申请日：2018-02-16

Applicant: Battelle Energy Alliance, LLC

Inventor： David N. Thompson ,  William A. Apel ,  Vicki S. Thompson ,  David W. Reed ,  Jeffrey A. Lacey ,  Emily D. Henriksen

IPC: C12P19/14 ,  C12N9/80 ,  C12N9/18 ,  C12N9/88 ,  C12P19/00 ,  C12N9/10 ,  C12N9/16 ,  C12N9/24 ,  C12N9/26 ,  C12N9/42 ,  C12N9/40 ,  C12N9/38 ,  C12N15/52 ,  C12N9/34 ,  C12P19/02

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.

公开(公告)号：US20180135037A1

公开(公告)日：2018-05-17

申请号：US15865757

申请日：2018-01-09

Applicant: Battelle Energy Alliance, LLC

Inventor： Vicki S. Thompson ,  William A. Apel ,  Jeffrey A. Lacey ,  Brady D. Lee ,  David W. Reed ,  Francisco F. Roberto ,  David N. Thompson

IPC: C12N9/88 ,  C12N15/75 ,  C12N9/00 ,  C12N15/74 ,  C12N9/10

CPC classification number: C12N9/88 ,  C12N9/00 ,  C12N9/1029 ,  C12N15/74 ,  C12N15/75 ,  C12Y203/01009 ,  C12Y402/01055

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.

公开(公告)号：US20170107524A1

公开(公告)日：2017-04-20

申请号：US15395184

申请日：2016-12-30

Applicant: Battelle Energy Alliance, LLC

Inventor： Brady D. Lee ,  Deborah T. Newby ,  Jeffrey A. Lacey ,  David N. Thompson ,  Vicki S. Thompson ,  William A. Apel ,  Francisco F. Roberto ,  David W. Reed

IPC: C12N15/74 ,  C07K14/195

CPC classification number: C12N15/74 ,  C07K14/195 ,  C12N9/00 ,  C12N9/1007 ,  C12N9/52 ,  C12N15/87 ,  C12Y201/01072

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering recombination inside or outside of a cell using isolated and/or purified polypeptides and/or nucleic acid sequences from Alicyclobacillus acidocaldarius.

公开(公告)号：US20170058281A1

公开(公告)日：2017-03-02

申请号：US15347936

申请日：2016-11-10

Applicant: Battelle Energy Alliance, LLC

Inventor： Brady D. Lee ,  David N. Thompson ,  William A. Apel ,  Vicki S. Thompson ,  David W. Reed ,  Jeffrey A. Lacey

IPC: C12N15/63 ,  C07K14/195 ,  C12N15/74

CPC classification number: C12N15/635 ,  C07K14/195 ,  C12N15/74

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of modulating transcription or transcription or transcriptional control using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.

Abstract translation: 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 进一步提供的是使用分离的和/或纯化的多肽和来自酸热环酸杆菌的核酸序列调节转录或转录或转录控制的方法。

公开(公告)号：US20160298158A1

公开(公告)日：2016-10-13

申请号：US15191113

申请日：2016-06-23

Applicant: Battelle Energy Alliance, LLC

Inventor： David N. Thompson ,  William A. Apel ,  Vicki S. Thompson ,  David W. Reed ,  Jeffrey A. Lacey ,  Emily D. Henriksen

IPC: C12P19/14 ,  C12N9/16 ,  C12N9/34 ,  C12N9/24 ,  C12N9/80 ,  C12N9/42 ,  C12N9/40 ,  C12N9/18 ,  C12N9/38 ,  C12P19/02 ,  C12N9/88

CPC classification number: C12P19/14 ,  C12N9/1051 ,  C12N9/16 ,  C12N9/18 ,  C12N9/2402 ,  C12N9/2408 ,  C12N9/2428 ,  C12N9/2434 ,  C12N9/2437 ,  C12N9/2445 ,  C12N9/2465 ,  C12N9/2471 ,  C12N9/248 ,  C12N9/2482 ,  C12N9/2494 ,  C12N9/80 ,  C12N9/88 ,  C12N15/52 ,  C12P19/00 ,  C12P19/02 ,  C12Y204/0102 ,  C12Y301/01001 ,  C12Y301/01006 ,  C12Y301/01073 ,  C12Y301/02004 ,  C12Y302/01008 ,  C12Y302/01015 ,  C12Y302/0102 ,  C12Y302/01021 ,  C12Y302/01022 ,  C12Y302/01037 ,  C12Y302/01055 ,  C12Y302/01078 ,  C12Y302/01091 ,  C12Y302/01131 ,  C12Y302/01133 ,  C12Y302/01139 ,  C12Y305/01 ,  C12Y402/01007 ,  C12Y402/01008

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.

公开(公告)号：US09029114B2

公开(公告)日：2015-05-12

申请号：US14055966

申请日：2013-10-17

Applicant: Battelle Energy Alliance, LLC

Inventor： Brady D. Lee ,  Deborah T. Newby ,  Jeffrey A. Lacey ,  David N. Thompson ,  Vicki S. Thompson ,  William A. Apel ,  Francisco F. Roberto ,  David W. Reed

IPC: C12N9/00 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04 ,  C12N15/87 ,  C12N9/52 ,  C12N9/10

CPC classification number: C12N15/74 ,  C07K14/195 ,  C12N9/00 ,  C12N9/1007 ,  C12N9/52 ,  C12N15/87 ,  C12Y201/01072

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering recombination inside or outside of a cell using isolated and/or purified polypeptides and/or nucleic acid sequences from Alicyclobacillus acidocaldarius.

Abstract translation: 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 进一步提供的是使用分离和/或纯化的多肽和/或酸碱热杆菌的核酸序列调节或改变细胞内部或外部的重组的方法。

公开(公告)号：US20150023568A1

公开(公告)日：2015-01-22

申请号：US14209720

申请日：2014-03-13

Applicant: Battelle Energy Alliance, LLC

Inventor： Jeffrey A. Lacey ,  Steve Marmer ,  David Max Woodhead ,  Shawna Park

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G06K9/3216 ,  G01N21/253 ,  G01N21/553 ,  G01N21/6452 ,  G01N33/6854 ,  G01N2021/1765 ,  G01N2035/00158 ,  G06K9/00134 ,  G06K2209/07 ,  G06T7/0008 ,  G06T7/73 ,  G06T2207/30072

Abstract: Computing systems, computer-readable media and methods are disclosed. In the computing system, an image capture device captures an image of a protein array including spots of predetermined proteins, wherein some of the spots have bound to a biological material having individual-specific antibodies to form immune complexes and some of the immune complexes have interacted with a detection agent to generate a visible image therefrom. The computing system may be operably coupled to the image capture device and processes the captured image of the protein array to determine control locations of a plurality of control spots in known locations on the protein array. The computing system also extrapolates expected locations of all other spots on the protein array from the control locations.

Abstract translation: 公开了计算系统，计算机可读介质和方法。 在计算系统中，图像捕获装置捕获包含预定蛋白质斑点的蛋白质阵列的图像，其中一些斑点已经结合到具有单个特异性抗体的生物材料上以形成免疫复合物，并且一些免疫复合物已相互作用 具有检测剂以从其产生可见图像。 计算系统可以可操作地耦合到图像捕获装置并处理所捕获的蛋白质阵列的图像，以确定蛋白质阵列上已知位置中多个控制点的控制位置。 计算系统还从控制位置外推蛋白质阵列上所有其他斑点的预期位置。

公开(公告)号：US08575323B2

公开(公告)日：2013-11-05

申请号：US13721172

申请日：2012-12-20

Applicant: Battelle Energy Alliance, LLC

Inventor： David N. Thompson ,  William A. Apel ,  Vicki S. Thompson ,  David W. Reed ,  Jeffrey A. Lacey

IPC: C07H21/04 ,  C12N15/63 ,  C12P21/00

CPC classification number: C07K14/195

Abstract: Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for transporting sugars across cell membranes using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.