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公开(公告)号：US07360341B2
公开(公告)日：2008-04-22
申请号：US10660528
申请日：2003-09-12
摘要： A column mounted shoring bracket has a support sub-assembly attached to a column or other supporting surface, a jack sub-assembly attached to the support and a head sub-assembly attached to a part of the jack that varies in height relative to the support. The head has a head base that supports one or more rollers for moving a form. The head also has a supporting plate for supporting the form. The supporting plate is connected to the head base so that it may be slid upwards and fixed in a position where the top of the supporting plate is above the top of the rollers, for example to carry the weight of a slab being built, or slid downwards so that the top of the supporting plate is below the top of the rollers which do not have to carry the weight of the slab being built. The angular position of the rollers may be aligned with an external reference such as the side of a column, a wall, or a jig. The bracket is adapted for use with parts of forms that may be made or assembled in or adjusted between a set of widths within a range that differ from each other by a selected increment. The forms include structures for spanning between shoring brackets or other supports that can be pre-cambered so as to have acceptable deflection when loaded.
摘要翻译： 柱安装的支架支架具有附接到柱或其他支撑表面的支撑子组件，附接到支撑件的千斤顶子组件和附接到插座的相对于支撑件高度变化的插座的一部分的头部子组件 。 头部具有头部基座，其支撑用于移动表格的一个或多个滚筒。 头部还具有支撑板的支撑板。 支撑板连接到头基部，使得其可以向上滑动并固定在支撑板的顶部高于辊的顶部的位置，例如以承载正在建造或滑动的板坯的重量 使得支撑板的顶部在辊的顶部之下，其不必承载正在建造的板坯的重量。 辊的角度位置可以与诸如柱，壁或夹具的外部参考物对准。 支架适用于可以在通过所选择的增量彼此不同的范围内的一组宽度之间制成或组装在一起或在一组宽度之间进行调整的部件。 这些形式包括在支撑托架或其他支撑件之间跨越的结构，其可以被预先弯曲以便在加载时具有可接受的偏转。
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公开(公告)号：US5813185A
公开(公告)日：1998-09-29
申请号：US639574
申请日：1996-04-29
申请人： George W. Jackson
发明人： George W. Jackson
IPC分类号： E04C5/16 , E04G17/065 , E04B1/02 , E04C3/30
CPC分类号： E04C5/16 , E04C5/165 , E04G17/0657 , Y10S411/901 , Y10S411/903
摘要： A tie rod assembly for use with forms for forming a wall of pourable, curable material. Each assembly has a rod having opposite threaded ends and two spacers. Each of the spacers has a first conical section having a recessed opening at an apex region of a concave conical guide surface and a hexagonal recess surrounding the apex region, and a second conical section having a threaded bore communicating with the apex opening. The threaded bore has a coil thread nut integrated with the conical second section. The concave conical guide presents a target for directing a remotely inserted bolt towards the apex region for engagement with the coil thread nut.
摘要翻译： 一种用于形成可浇注的可固化材料壁的形式的拉杆组件。 每个组件具有具有相对的螺纹端和两个间隔件的杆。 每个间隔件具有第一锥形部分，其具有在凹形锥形引导表面的顶点区域处的凹入开口和围绕顶点区域的六边形凹槽，以及具有与顶点开口连通的螺纹孔的第二锥形部分。 螺纹孔具有与锥形第二部分一体化的线圈螺母。 凹形圆锥形引导件提供用于将远程插入的螺栓朝向顶点区域引导以与线圈螺纹螺母接合的目标。
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公开(公告)号：US5112155A
公开(公告)日：1992-05-12
申请号：US787426
申请日：1991-11-04
申请人： George W. Jackson
发明人： George W. Jackson
IPC分类号： E04G7/30
CPC分类号： E04G7/308 , E04G7/305 , Y10T403/30
摘要： A connector for assembling components of scaffolding is disclosed comprising a barrel having an opposite end having a longitudinally extending slot. A pivot pin and an abutment pin extends across the slot and mounted at the opposite end of the barrel. A free hanging latch has an offset aperture for pivotally mounting onto the pivot pin and a channel for receiving the abutment pin. One end of the channel is configured to abut with the abutment pin when the latch is in a locked position and the other end of the channel being configured to abut the abutment pin when the latch is in an unlocked position. The latch has a tab which is offset beyond the end of the barrel whereby pressing on the tab, the latch pivots from the locked position to the unlocked position allowing egress of the brace from the connector.
摘要翻译： 公开了一种用于组装脚手架组件的连接器，其包括具有相对端的具有纵向延伸狭槽的筒体。 枢轴销和邻接销延伸穿过槽并安装在桶的相对端。 自由悬挂闩锁具有用于枢转地安装到枢转销上的偏移孔和用于接收抵靠销的通道。 当闩锁处于锁定位置时，通道的一端构造成与邻接销抵接，并且当闩锁处于解锁位置时，通道的另一端构造成抵靠邻接销。 闩锁具有突出部，其突出超过筒的端部，由此按压突出部，闩锁从锁定位置枢转到解锁位置，从而允许从连接器排出支架。
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公开(公告)号：US09035034B2
公开(公告)日：2015-05-19
申请号：US13748566
申请日：2013-01-23
申请人： George W. Jackson
发明人： George W. Jackson
IPC分类号： C07H21/04 , C12N15/115
CPC分类号： C12N15/115 , C12N2310/16 , C12N2320/11 , C12N2330/31
摘要： The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules. The present invention further relates to methods for generating, for example, functional biomolecules, particularly to functional nucleic acids, that bind with functional activity to another biomolecule, such as a receptor molecule. More than one or multiple targets as used herein may generally include different types of targets, and/or may also include a multitude of a singular type of targets at different conditions, such as, for example, temperature, pH, chemical environment, and/or any other appropriate conditions.
摘要翻译： 本发明涉及功能性配体与靶分子，特别是功能性核酸及其修饰，以及用于同时产生例如多种不同功能生物分子的方法，特别涉及同时产生多种不同功能性核酸的方法。 本发明还涉及与靶分子具有亲和力结合的功能性配体。 本发明还涉及用于产生例如功能性生物分子，特别是功能性核酸的方法，所述功能性生物分子与另一生物分子例如受体分子的功能活性结合。 本文使用的多于一个或多个靶标通常可以包括不同类型的靶标，和/或还可以包括在不同条件下的多种单一类型的靶标，例如温度，pH，化学环境和/ 或任何其他适当的条件。
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公开(公告)号：US20130245243A1
公开(公告)日：2013-09-19
申请号：US13748566
申请日：2013-01-23
申请人： George W. Jackson
发明人： George W. Jackson
IPC分类号： C12N15/115
CPC分类号： C12N15/115 , C12N2310/16 , C12N2320/11 , C12N2330/31
摘要： The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules. The present invention further relates to methods for generating, for example, functional biomolecules, particularly to functional nucleic acids, that bind with functional activity to another biomolecule, such as a receptor molecule. More than one or multiple targets as used herein may generally include different types of targets, and/or may also include a multitude of a singular type of targets at different conditions, such as, for example, temperature, pH, chemical environment, and/or any other appropriate conditions.
摘要翻译： 本发明涉及功能性配体与靶分子，特别是功能性核酸及其修饰，以及用于同时产生例如多种不同功能生物分子的方法，特别涉及同时产生多种不同功能性核酸的方法。 本发明还涉及与靶分子具有亲和力结合的功能性配体。 本发明还涉及用于产生例如功能性生物分子，特别是功能性核酸的方法，所述功能性生物分子与另一生物分子例如受体分子的功能活性结合。 本文使用的多于一个或多个靶标通常可以包括不同类型的靶标，和/或还可以包括在不同条件下的多种单一类型的靶标，例如温度，pH，化学环境和/ 或任何其他适当的条件。
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公开(公告)号：US6103078A
公开(公告)日：2000-08-15
申请号：US390740
申请日：1999-09-07
申请人： G. Duncan Hitchems , Harry Jabs , Craig C. Andrews , Oliver J. Murphy , William White , George W. Jackson , Charles L. C. Tennakoon
发明人： G. Duncan Hitchems , Harry Jabs , Craig C. Andrews , Oliver J. Murphy , William White , George W. Jackson , Charles L. C. Tennakoon
CPC分类号： H01M8/1088 , B01D61/445 , B01D61/52 , C08J5/2275 , H01M8/1023 , H01M8/1039 , H01M8/106 , H01M8/1072 , C08J2323/12 , H01M2300/0082 , Y02P70/56
摘要： The present invention provides improved ionically conducting membranes having internal passages therethrough and methods for making the improved membranes. The membranes may be formed from any ionically conducting material. In particular, the membranes may be formed of a single ionically conducting material, such as in a cation-conductive or anion-conductive membrane, or a plurality of ionically conducting material, such as in a bipolar membrane having a cation-selective region, an anion-selective region, and an interfacial region between the anion-selective region and the cation-selective region.
摘要翻译： 本发明提供了具有内部通道的改进的离子导电膜及其制备方法。 膜可以由任何离子导电材料形成。 特别地，膜可以由单个离子导电材料形成，例如在阳离子导电或阴离子导电膜中，或多个离子导电材料，例如具有阳离子选择性区域的双极膜， 阴离子选择性区域以及阴离子选择性区域和阳离子选择性区域之间的界面区域。
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公开(公告)号：US5846446A
公开(公告)日：1998-12-08
申请号：US848610
申请日：1997-04-29
申请人： George W. Jackson
发明人： George W. Jackson
IPC分类号： F25C1/24
CPC分类号： F25C1/243
摘要： A first ice making bag (110) comprises a first envelope (112) which comprises a first envelope top (112T) and a first envelope bottom (112B). The first ice making bag (110) further comprises a first binding (114) which comprises a first peripheral binding (114A). A first left peripheral opening binding (114AL), and a first right peripheral opening binding (114AR). The first left peripheral opening binding (114AL) and the first right peripheral opening binding (114AR) form a gap therebetween. The first binding (114) functions to form a pocket between the first envelope top (112T) and the first envelope bottom (112B). The first ice making bag (110) further comprises at least one first opening binding (114B) forming an air channel between the first left peripheral opening binding (114AL) or the first right peripheral opening binding (114AR) and the at least one first opening binding (114B). An user holds the first ice making bag (110) in a vertical position pouring liquid in through the gap into the pocket formed between the first envelope top (112T) and a first envelope bottom (112B) and placing the first ice making bag (110) in a freezer to form first ice (118). The air channel functions to facilitate release of air previously entrapped in the pocket during filing.
摘要翻译： 第一制冰袋（110）包括第一封套（112），其包括第一封套顶部（112T）和第一封套底部（112B）。 第一制冰袋（110）还包括包括第一外围装订件（114A）的第一装订件（114）。 第一左周边开口装订（114AL）和第一右周边开口装订（114AR）。 第一左周边开口装订（114AL）和第一右周围开口装订（114AR）在其间形成间隙。 第一装订（114）用于在第一封套顶部（112T）和第一封套底部（112B）之间形成一个凹槽。 第一制冰袋（110）还包括在第一左周围开口装订（114AL）或第一右周围开口装订（114AR）和至少一个第一开口（114AR）之间形成空气通道的至少一个第一开口装订（114B） 绑定（114B）。 使用者将第一制冰袋（110）保持在垂直位置，将液体通过间隙倾倒入形成在第一封套顶部（112T）和第一封套底部（112B）之间的凹穴中，并将第一制冰袋（110） ）在冷冻器中形成第一个冰（118）。 空气通道用于在归档期间促进先前夹在口袋中的空气的释放。
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公开(公告)号：US20160264970A1
公开(公告)日：2016-09-15
申请号：US15065837
申请日：2016-03-09
申请人： George W. Jackson , Darryl Bornhop
发明人： George W. Jackson , Darryl Bornhop
IPC分类号： C12N15/115 , G01N21/77 , G01N21/47 , G01N33/53
CPC分类号： C12N15/115 , C12N2310/16 , C12N2310/531 , G01N21/47 , G01N33/5308 , G01N33/542 , G01N2021/4709
摘要： The present invention relates to methods and compositions for enhancing backscattering interferometry (BSI) in detection of biomolecular interactions, particularly to methods and compositions for enhancing BSI utilizing label-free aptamers, and more particularly to methods and compositions for enhancing BSI utilizing high conformational change aptamers, which may change in conformation when the aptamers bind to their target molecules.
摘要翻译： 本发明涉及用于增强背景散射干涉测量（BSI）检测生物分子相互作用的方法和组合物，特别涉及利用无标记的适配子增强BSI的方法和组合物，更具体地涉及利用高构象变化适体增强BSI的方法和组合物 ，当适体与其靶分子结合时，其可能在构象上改变。
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公开(公告)号：US20120165225A1
公开(公告)日：2012-06-28
申请号：US12121658
申请日：2008-05-15
CPC分类号： C12N15/1048
摘要： The present invention is generally directed to novel functionalized biomolecules and methods for generating such biomolecules. Biomolecules may generally include nucleic acids, peptides, multicomponent molecular complexes and/or any other molecular products that may be produced by living organisms. The present invention is further directed to cells and/or organisms manipulated to produce such functionalized biomolecules. The cells contemplated by the present invention include both prokaryotic as well as eukaryotic cells. The functionalized biomolecules are produced via materials introduced into the cell using standard molecular biology techniques or are incorporated within the genomic nucleic acid of a cell by standard recombination techniques. Further contemplated is the use of such cells for sequestration of target molecules within the cells.
摘要翻译： 本发明一般涉及新的功能化生物分子和产生这种生物分子的方法。 生物分子通常可以包括可由活生物体产生的核酸，肽，多组分分子复合物和/或任何其它分子产物。 本发明进一步涉及被操作以产生这种官能化生物分子的细胞和/或生物。 本发明考虑的细胞包括原核细胞以及真核细胞。 功能化生物分子通过使用标准分子生物学技术引入细胞的材料产生，或通过标准重组技术并入细胞的基因组核酸中。 进一步考虑的是使用这种细胞来封存细胞内的靶分子。
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公开(公告)号：US20120121533A1
公开(公告)日：2012-05-17
申请号：US13296163
申请日：2011-11-14
申请人： George W. Jackson
发明人： George W. Jackson
CPC分类号： C12N15/115 , A61K31/713 , C12N2310/16 , C12N2310/334 , C12N2310/335
摘要： The present invention is directed to nucleic acid ligands to LL37, methods for producing said nucleic acid ligands, and methods for utilizing said nucleic acid ligands. In one exemplary embodiment, for example, this invention relates to nucleic acid ligands exhibiting high specific binding affinity to LL37 peptides, precursors and/or portions thereof. Further, the nucleic acid ligands may bind competitively with native ligands of LL37 and may also inhibit and/or interfere with LL37 function, such as by binding to LL37.
摘要翻译： 本发明涉及LL37的核酸配体，用于产生所述核酸配体的方法，以及利用所述核酸配体的方法。 在一个示例性实施方案中，例如，本发明涉及对LL37肽，前体和/或其部分表现出高特异性结合亲和力的核酸配体。 此外，核酸配体可以与LL37的天然配体竞争性结合，并且还可以抑制和/或干扰LL37功能，例如通过结合LL37。
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