Nanofluidic channel with embedded transverse nanoelectrodes and method of fabricating for same
    1.
    发明申请
    Nanofluidic channel with embedded transverse nanoelectrodes and method of fabricating for same 有权
    具有嵌入式横向纳米电极的纳米流体通道及其制造方法

    公开(公告)号:US20110285409A1

    公开(公告)日:2011-11-24

    申请号:US13143086

    申请日:2010-01-29

    CPC classification number: G01N33/48721 G01N15/12 G01N2015/1254 Y10T29/49124

    Abstract: A method for forming a nanofluidic channel measuring system is disclosed. The method includes forming a first trench in a substrate, forming a second trench in the substrate, the first trench and the second trench are separated by a first width, providing a first conductor pad at a first location, providing a second conductor pad at a second location, forming a first nano-wire for coupling the first conductor pad with the second conductor pad, and forming a nano-channel through the first nano-wire, the nano-channel also coupling the first trench and the second trench, the nano-channel configured to sever the first nano-wire. A nanofluidic channel measuring system is also disclosed.

    Abstract translation: 公开了一种形成纳米流体通道测量系统的方法。 该方法包括在衬底中形成第一沟槽,在衬底中形成第二沟槽,第一沟槽和第二沟槽分开第一宽度,在第一位置提供第一导体焊盘,在第一位置提供第二导体焊盘, 形成用于将所述第一导体焊盘与所述第二导体焊盘耦合的第一纳米线,以及通过所述第一纳米线形成纳米通道,所述纳米通道还耦合所述第一沟槽和所述第二沟槽,所述纳米线 - 通道被配置为切断第一纳米线。 还公开了一种纳米流体通道测量系统。

    Nanofluidic channel with embedded transverse nanoelectrodes and method of fabrication for same
    3.
    发明授权
    Nanofluidic channel with embedded transverse nanoelectrodes and method of fabrication for same 有权
    具有嵌入式横向纳米电极的纳米流体通道及其制造方法

    公开(公告)号:US08907684B2

    公开(公告)日:2014-12-09

    申请号:US13143086

    申请日:2010-01-29

    CPC classification number: G01N33/48721 G01N15/12 G01N2015/1254 Y10T29/49124

    Abstract: A method for forming a nanofluidic channel measuring system is disclosed. The method includes forming a first trench in a substrate, forming a second trench in the substrate, the first trench and the second trench are separated by a first width, providing a first conductor pad at a first location, providing a second conductor pad at a second location, forming a first nano-wire for coupling the first conductor pad with the second conductor pad, and forming a nano-channel through the first nano-wire, the nano-channel also coupling the first trench and the second trench, the nano-channel configured to sever the first nano-wire. A nanofluidic channel measuring system is also disclosed.

    Abstract translation: 公开了一种形成纳米流体通道测量系统的方法。 该方法包括在衬底中形成第一沟槽,在衬底中形成第二沟槽,第一沟槽和第二沟槽分开第一宽度,在第一位置提供第一导体焊盘,在第一位置提供第二导体焊盘, 形成用于将所述第一导体焊盘与所述第二导体焊盘耦合的第一纳米线,以及通过所述第一纳米线形成纳米通道,所述纳米通道还耦合所述第一沟槽和所述第二沟槽,所述纳米线 - 通道被配置为切断第一纳米线。 还公开了一种纳米流体通道测量系统。

    Touch-actuated micropump for transdermal drug delivery and method of use
    5.
    发明授权
    Touch-actuated micropump for transdermal drug delivery and method of use 有权
    用于透皮药物递送的触摸式微型泵和使用方法

    公开(公告)号:US09173994B2

    公开(公告)日:2015-11-03

    申请号:US13214990

    申请日:2011-08-22

    Abstract: A micropump device. The micropump device includes a first layer forming a first chamber configured to store a working material, a second chamber defined by a deflectable membrane in fluid communication with the first chamber and configured to deflect in response to a pressure increase in the first chamber in response to a volume increase in the first chamber, the second chamber configured to store a drug compound to be delivered to a subject's vascular system, and at least one needle in fluid communication with the second chamber and configured to penetrate a subject's skin to pump the drug compound in response to the deflection of the deflectable membrane.

    Abstract translation: 微型泵装置。 微型泵装置包括形成第一室的第一层,其被配置为存储工作材料,第二室由可偏转膜限定,与第一室流体连通,并且被配置为响应于第一室中的压力增加而响应于 所述第一室中的体积增加,所述第二室被配置为储存要输送到受试者的血管系统的药物化合物,以及至少一个与所述第二室流体连通的针,并且构造成穿透受试者的皮肤以泵送药物组合物 响应于可偏转膜的偏转。

    Reflective Diffractometric Hydrogel Sensor for Biological and Chemical Detection
    7.
    发明申请
    Reflective Diffractometric Hydrogel Sensor for Biological and Chemical Detection 有权
    用于生物和化学检测的反射衍射水凝胶传感器

    公开(公告)号:US20120170050A1

    公开(公告)日:2012-07-05

    申请号:US13311307

    申请日:2011-12-05

    CPC classification number: G01B11/14 B82Y35/00

    Abstract: A reflective diffractometric hydrogel sensor includes an upper layer, including a microfluidic chamber formed from a substantially transparent material and configured to contain a solution, a reflective diffraction grating positioned within the microfluidic chamber, the diffraction grating including a plurality of hydrogel strips configured to change in dimension in response to a stimulus, each hydrogel strip having a top surface coated with a reflective material and a bottom surface in contact with the upper layer substrate, and a reflective surface below the reflective diffraction grating wherein when a coherent light is incident upon and reflected from the upper layer at an angle substantially normal to the upper layer an interference diffraction pattern results, including a first diffraction mode, a light intensity of which indicates the relative distance between the top surfaces of the plurality of hydrogel strips and the reflective surface.

    Abstract translation: 反射衍射水凝胶传感器包括上层,包括由基本上透明的材料形成的微流体室,并且被构造为容纳溶液,位于微流体室内的反射衍射光栅,衍射光栅包括多个水凝胶条,其被配置为在 每个水凝胶条具有涂覆有反射材料的顶表面和与上层基底接触的底表面,以及反射衍射光栅下方的反射表面,其中当相干光入射并反射时 导致基本垂直于上层的角度从上层开始产生干涉衍射图案,其包括第一衍射模式,其第一衍射模式的光强表示多个水凝胶条带的顶表面与反射表面之间的相对距离。

    DC offset cancellation techniques
    8.
    发明申请
    DC offset cancellation techniques 审中-公开
    直流偏移消除技术

    公开(公告)号:US20050107674A1

    公开(公告)日:2005-05-19

    申请号:US10953080

    申请日:2004-09-29

    CPC classification number: A61B5/04004 A61B5/04001

    Abstract: The invention provides an electro-physiological system and various techniques for substantially canceling direct current (DC) offset while amplifying low frequency biological signals, e.g. local field potentials. In particular, the measured results of the invention show a DC offset rejection ratio of approximately greater than 100 dB. In one embodiment, the invention provides a method comprising receiving a biological signal including a frequency component and a DC (direct current) component, attenuating the frequency component of the biological signal to generate a second signal, and subtracting the second signal from the biological signal to generate a third signal.

    Abstract translation: 本发明提供了一种电生理系统和用于基本上消除直流(DC)偏移同时放大低频生物信号的各种技术,例如, 局部场势。 特别地,本发明的测量结果示出了大约大于100dB的DC偏移抑制比。 在一个实施例中,本发明提供了一种方法,包括接收包括频率分量和DC(直流)分量的生物信号,衰减生物信号的频率分量以产生第二信号,以及从生物信号中减去第二信号 以产生第三信号。

    Reflective diffractometric hydrogel sensor for biological and chemical detection
    10.
    发明授权
    Reflective diffractometric hydrogel sensor for biological and chemical detection 有权
    用于生物和化学检测的反射衍射水凝胶传感器

    公开(公告)号:US08663563B2

    公开(公告)日:2014-03-04

    申请号:US13311307

    申请日:2011-12-05

    CPC classification number: G01B11/14 B82Y35/00

    Abstract: A reflective diffractometric hydrogel sensor includes an upper layer, including a microfluidic chamber formed from a substantially transparent material and configured to contain a solution, a reflective diffraction grating positioned within the microfluidic chamber, the diffraction grating including a plurality of hydrogel strips configured to change in dimension in response to a stimulus, each hydrogel strip having a top surface coated with a reflective material and a bottom surface in contact with the upper layer substrate, and a reflective surface below the reflective diffraction grating wherein when a coherent light is incident upon and reflected from the upper layer at an angle substantially normal to the upper layer an interference diffraction pattern results, including a first diffraction mode, a light intensity of which indicates the relative distance between the top surfaces of the plurality of hydrogel strips and the reflective surface.

    Abstract translation: 反射衍射水凝胶传感器包括上层,包括由基本上透明的材料形成的微流体室,并且被构造为容纳溶液,位于微流体室内的反射衍射光栅,衍射光栅包括多个水凝胶条,其被配置为在 每个水凝胶条具有涂覆有反射材料的顶表面和与上层基底接触的底表面,以及反射衍射光栅下方的反射表面,其中当相干光入射并反射时 导致基本垂直于上层的角度从上层开始产生干涉衍射图案,其包括第一衍射模式,其第一衍射模式的光强表示多个水凝胶条带的顶表面与反射表面之间的相对距离。

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