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    Modular automated chromatography system
    1.
    发明授权
    Modular automated chromatography system 有权

    公开(公告)号：US10900938B2

    公开(公告)日：2021-01-26

    申请号：US16595766

    申请日：2019-10-08

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Robert Iovanni ,  Alec Gordon ,  Bob Avarbock ,  Wayne Bland ,  Glenn Price ,  Ken Baker ,  Farah Mavandadi ,  Christof Schultz

    IPC: G01N30/38 ,  G01N30/46 ,  B01D15/18 ,  G01N30/88 ,  G05D7/06 ,  G05B15/02 ,  B01D15/10 ,  G01N35/00

    Abstract: Valves, pumps, detectors, sample loops, fraction collectors and the like are individually incorporated into modules that are mountable at individual mounting sites on a base unit which also supports one or more chromatography columns. Each module includes fluid connections to other modules and a microcontroller joining the module to a computed and monitor through an electronic connector at each mounting site. The fluid connections between the modules and the column(s) are removed from the electronic connections and accessible to the user. A software platform may recognize the modules and their locations, coordinate fluid connections between the modules, and provide a variety of control, monitoring, data generating and data processing functions to generate chromatographic data. The software platform may also provide graphical tools for designing chromatographic methods from a library of phases.

    Modular automated chromatography system
    3.
    发明授权
    Modular automated chromatography system 有权

    公开(公告)号：US10444204B2

    公开(公告)日：2019-10-15

    申请号：US16104545

    申请日：2018-08-17

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Robert Iovanni ,  Alec Gordon ,  Bob Avarbock ,  Wayne Bland ,  Glenn Price ,  Ken Baker ,  Farah Mavandadi ,  Christof Schultz

    IPC: B01D15/18 ,  G01N30/46 ,  G01N30/38 ,  G01N30/88 ,  G05B15/02 ,  G05D7/06 ,  B01D15/10 ,  G01N35/00

    Abstract: Valves, pumps, detectors, sample loops, fraction collectors and the like are individually incorporated into modules that are mountable at individual mounting sites on a base unit which also supports one or more chromatography columns. Each module includes fluid connections to other modules and a microcontroller joining the module to a computed and monitor through an electronic connector at each mounting site. The fluid connections between the modules and the column(s) are removed from the electronic connections and accessible to the user. A software platform may recognize the modules and their locations, coordinate fluid connections between the modules, and provide a variety of control, monitoring, data generating and data processing functions to generate chromatographic data. The software platform may also provide graphical tools for designing chromatographic methods from a library of phases.

    Modular automated chromatography system
    6.
    发明授权
    Modular automated chromatography system 有权

    公开(公告)号：US10401335B2

    公开(公告)日：2019-09-03

    申请号：US16104443

    申请日：2018-08-17

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Robert Iovanni ,  Alec Gordon ,  Bob Avarbock ,  Wayne Bland ,  Glenn Price ,  Ken Baker ,  Farah Mavandadi ,  Christof Schultz

    IPC: B01D15/18 ,  G01N30/46 ,  G01N30/38 ,  G01N30/88 ,  G05B15/02 ,  G05D7/06 ,  B01D15/10 ,  G01N35/00

    Abstract: Valves, pumps, detectors, sample loops, fraction collectors and the like are individually incorporated into modules that are mountable at individual mounting sites on a base unit which also supports one or more chromatography columns. Each module includes fluid connections to other modules and a microcontroller joining the module to a computed and monitor through an electronic connector at each mounting site. The fluid connections between the modules and the column(s) are removed from the electronic connections and accessible to the user. A software platform may recognize the modules and their locations, coordinate fluid connections between the modules, and provide a variety of control, monitoring, data generating and data processing functions to generate chromatographic data. The software platform may also provide graphical tools for designing chromatographic methods from a library of phases.

    ASSAY CARTRIDGE
    7.
    发明申请
    ASSAY CARTRIDGE 审中-公开
    测试盒

    公开(公告)号：US20160266099A1

    公开(公告)日：2016-09-15

    申请号：US15064365

    申请日：2016-03-08

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Glenn Price ,  Chris Charlton ,  William Link ,  Robert Alan Iovanni ,  Anthony F. Prestigiacomo

    IPC: G01N33/53

    CPC classification number: B01L3/5023 ,  B01L3/5025 ,  B01L3/52 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0621 ,  B01L2200/143 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/069 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2400/0457

    Abstract: In one arrangement, a cartridge includes a cartridge body defining a holding compartment, first and second fractioning compartments, and a number of flow channels formed within the cartridge body. A predetermined quantity of fluid can be held in the holding compartment when the cartridge body is held in a first orientation, and can be poured from the holding compartment to the first fractioning compartment by rotating the cartridge body about a predefined rotation axis to a second orientation, spilling the fluid from the holding compartment to the first fractioning compartment through one of the flow channels. The first fractioning compartment is such that when the cartridge body is in the second orientation, not all of the fluid can be contained in the first fractioning compartment, and fluid that overflows the first fractioning compartment flows through a second flow channel to the second fractioning compartment.

    Abstract translation: 在一种布置中，盒包括限定保持室，第一和第二分级隔室以及形成在盒体内的多个流动通道的盒体。 当盒体被保持在第一方向时，预定量的流体可以被保持在保持室中，并且可以通过将盒体围绕预定义的旋转轴旋转到第二取向而从保持室倾倒到第一分馏室 通过其中一个流动通道将流体从储藏室溢出到第一分馏室。 第一分馏室使得当盒体处于第二取向时，并非所有流体都可以包含在第一分馏室中，并且溢出第一分馏室的流体流过第二流动通道至第二分馏室 。

    FLUID MANIPULATOR HAVING FLEXIBLE BLISTER
    8.
    发明申请
    FLUID MANIPULATOR HAVING FLEXIBLE BLISTER 有权
    具有柔性喷雾器的流体操纵器

    公开(公告)号：US20160089670A1

    公开(公告)日：2016-03-31

    申请号：US14500710

    申请日：2014-09-29

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Glenn Price ,  Luis Ortiz Hernandez ,  Robert Iovanni ,  William Link

    IPC: B01L3/00 ,  G01N33/72 ,  G01N33/536

    CPC classification number: B01L3/50273 ,  B01L3/502738 ,  B01L3/505 ,  B01L2300/0803 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0638

    Abstract: A system for fluid manipulation includes a composite wafer and a movable compression device. The composite wafer includes a flexible layer and a substantially rigid layer adhered to the flexible layer. The flexible layer defines one or more recesses that are covered by the substantially rigid layer to form one or more reservoirs and one or more fluid channels among the one or more reservoirs. The movable compression device contacts the flexible layer and is configured to progressively compress the flexible layer such that when the movable compression device traverses the flexible layer, fluid is forced through the one or more fluid channels and the one or more reservoirs in a sequence determined by the layout of the one or more fluid channels and the one or more reservoirs. Certain reservoirs may be pre-loaded with fluids and reagents for performing a specified medical test.

    Abstract translation: 用于流体操纵的系统包括复合晶片和可移动压缩装置。 复合晶片包括柔性层和粘附到柔性层的基本上刚性的层。 柔性层限定一个或多个由基本上刚性的层覆盖的凹部，以在一个或多个储存器中形成一个或多个储存器和一个或多个流体通道。 可移动压缩装置接触柔性层并且构造成逐渐压缩柔性层，使得当可移动压缩装置穿过柔性层时，流体被强制通过一个或多个流体通道和一个或多个储存器，其顺序由 一个或多个流体通道和一个或多个储存器的布局。 某些储存器可以预先装载用于执行特定医疗测试的流体和试剂。

    Chromatography System with LED-Based Light Source
    9.
    发明申请
    Chromatography System with LED-Based Light Source 审中-公开
    基于LED的光源色谱系统

    公开(公告)号：US20140191117A1

    公开(公告)日：2014-07-10

    申请号：US14152960

    申请日：2014-01-10

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Wayne Bland ,  Glenn Price ,  Donald Hutson

    IPC: G01J1/04

    CPC classification number: G01J1/0488 ,  G01J3/0213 ,  G01J3/10 ,  G01J3/42 ,  G01J2003/104 ,  G01J2003/421

    Abstract: A detector system having a single emitter body. The emitter body has a plurality of light emitting diodes (LEDs) for emitting a plurality of wavelengths. Each LED adapted to emit a different wavelength of light. A broadband filter is adapted to receive the plurality of wavelengths. A detector arrangement adapted to receive the plurality of wavelengths filtered by the broadband filter. A controller adapted to control the plurality of LEDs and detector arrangement.

    Abstract translation: 具有单个发射体的检测器系统。 发射体具有用于发射多个波长的多个发光二极管（LED）。 每个LED适于发射不同波长的光。 宽带滤波器适于接收多个波长。 一种适于接收由宽带滤波器滤波的多个波长的检测器装置。 一种适于控制多个LED和检测器装置的控制器。

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