知搜-全球专利检索

  1. Login
  2. Sign Up

Search Results

17 records (took 0.023 seconds)

    Probes for biochemical tests
    1.
    发明授权
    Probes for biochemical tests 有权

    公开(公告)号：US11199555B2

    公开(公告)日：2021-12-14

    申请号：US16421015

    申请日：2019-05-23

    Applicant: Access Medical Systems, LTD.

    Inventor： Hong Tan ,  Ming Xia ,  Yushan Tan ,  Jun Chen ,  Erhua Cao ,  Genqian Li ,  Robert F. Zuk

    IPC: G01N35/00 ,  G01N33/74 ,  B01L3/00 ,  G01N33/543 ,  G01N35/02 ,  G01N35/04

    Abstract: This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.

    Systems for immunoassay tests
    2.
    发明授权
    Systems for immunoassay tests 有权

    公开(公告)号：US10345319B2

    公开(公告)日：2019-07-09

    申请号：US15784966

    申请日：2017-10-16

    Applicant: Access Medical Systems, LTD.

    Inventor： Hong Tan ,  Ming Xia ,  Yushan Tan ,  Jun Chen ,  Erhua Cao ,  Genqian Li ,  Robert F. Zuk

    IPC: B65G47/90 ,  G01N35/00 ,  B01L3/00 ,  G01N33/543 ,  G01N35/02 ,  G01N35/04

    Abstract: This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.

    Optical sensor of bio-molecules using thin-film interferometer
    3.
    发明授权
    Optical sensor of bio-molecules using thin-film interferometer 有权
    使用薄膜干涉仪的生物分子的光学传感器

    公开(公告)号：US08940238B2

    公开(公告)日：2015-01-27

    申请号：US14095120

    申请日：2013-12-03

    Applicant: Access Medical Systems, Ltd.

    Inventor： Hong Tan ,  Yushan Tan ,  Erhua Cao ,  Ming Xia ,  Robert F. Zuk

    IPC: G01N21/00 ,  G01B9/02 ,  G02B6/26 ,  G02B6/36 ,  G01N21/45 ,  G01N21/77 ,  G02B6/00 ,  G01N21/63

    CPC classification number: G01N21/7703 ,  G01J3/45 ,  G01N21/45 ,  G01N21/648 ,  G01N21/8507 ,  G01N2021/7779 ,  G01N2201/062 ,  G01N2201/08 ,  G02B6/262 ,  G02B6/30

    Abstract: The present invention is directed to an assembly for use in detecting an analyte in a sample based on thin-film spectral interference. The assembly comprises a waveguide, a monolithic substrate optically coupled to the waveguide, and a thin-film layer directly bonded to the sensing side of the monolithic substrate. The refractive index of the monolithic substrate is higher than the refractive index of the transparent material of the thin-film layer. A spectral interference between the light reflected into the waveguide from a first reflecting surface and a second reflecting surface varies as analyte molecules in a sample bind to the analyte binding molecules coated on the thin-film layer.

    Abstract translation: 本发明涉及一种用于基于薄膜光谱干涉检测样品中的分析物的组件。 组件包括波导，光耦合到波导的单片基板，以及直接结合到整体式基板的感测侧的薄膜层。 单片基板的折射率高于薄膜层的透明材料的折射率。 当样品中的分析物分子结合到涂覆在薄膜层上的分析物结合分子时，从第一反射表面和第二反射表面反射到波导中的光之间的光谱干涉变化。

    Detection system for high sensitivity fluorescent assays
    5.
    发明授权
    Detection system for high sensitivity fluorescent assays 有权

    公开(公告)号：US10379116B2

    公开(公告)日：2019-08-13

    申请号：US15256319

    申请日：2016-09-02

    Applicant: Access Medical Systems, LTD.

    Inventor： Hong Tan ,  Robert F. Zuk ,  Yushan Tan ,  Erhua Cao ,  Min Xia ,  Jun Chen

    IPC: G01N33/543 ,  G01N21/64 ,  C08B37/00

    Abstract: This invention relates to a detection system for measuring a fluorescent signal in a fluorescent assay. The system comprises a probe having a small sensing surface bound with a fluorescent label, and a light source and a detector both mounted at the proximal side of the sensing surface of the substrate. The invention also relates to a method for detecting an analyte in a liquid sample using a probe tip having a small surface area (≤5 mm) and a high molecular weight polymer (≥1 MD) having multiple binding molecules and multiple fluorescent labels. The binding reaction is accelerated by flowing the reaction solutions laterally and moving the probe tip up and down in the reaction vessels. The invention furthers relates to a fluorescent labeling composition comprising a cross-linked FICOLL® molecule having a plurality of binding molecules and a plurality of fluorescent labels.

    Systems for immunoassay tests
    7.
    发明授权
    Systems for immunoassay tests 有权
    免疫测定系统

    公开(公告)号：US09468926B2

    公开(公告)日：2016-10-18

    申请号：US14301228

    申请日：2014-06-10

    Applicant: Access Medical Systems, LTD.

    Inventor： Hong Tan ,  Ming Xia ,  Yushan Tan ,  Jun Chen ,  Erhua Cao ,  Genqian Li ,  Robert F. Zuk

    IPC: B65G47/90 ,  B01L3/00 ,  G01N33/543 ,  G01N35/04 ,  G01N35/02

    CPC classification number: B01L3/52 ,  B01L3/502 ,  B01L3/527 ,  B01L2300/042 ,  B01L2300/045 ,  G01N33/54306 ,  G01N33/54353 ,  G01N33/54366 ,  G01N35/026 ,  G01N2035/0436

    Abstract: This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.

    Abstract translation: 本发明涉及进行免疫测定试验的装置。 所述装置包括：槽单元，具有沿着垂直方向具有沿着垂直方向保持探针的杆状部分的垂直方向的槽;以及推动销，其构造成沿水平方向移动，所述推动销能够驻留在 第一职位和第二职位。 当推销位于第一位置时，推针的尖端能够将探针的杆状部分压靠在凹槽上。 当推销位于第二位置时，推针的尖端与槽之间的距离大于探针的棒状部分的直径。

    SYSTEMS FOR IMMUNOASSAY TESTS
    9.
    发明申请
    SYSTEMS FOR IMMUNOASSAY TESTS 有权
    免疫测试系统

    公开(公告)号：US20140295578A1

    公开(公告)日：2014-10-02

    申请号：US14301228

    申请日：2014-06-10

    Applicant: Access Medical Systems, LTD.

    Inventor： Hong TAN ,  Ming Xia ,  Yushan Tan ,  Jun Chen ,  Erhua Cao ,  Genqian Ll ,  Robert F. Zuk

    IPC: B01L3/00

    CPC classification number: B01L3/52 ,  B01L3/502 ,  B01L3/527 ,  B01L2300/042 ,  B01L2300/045 ,  G01N33/54306 ,  G01N33/54353 ,  G01N33/54366 ,  G01N35/026 ,  G01N2035/0436

    Abstract: This invention relates to a cartridge for an immunoassay test. The cartridge comprises (a) a probe well comprising a probe and a cap, the cap being in a closed position to enclose the probe in the probe well, wherein the probe has a bottom tip coated with analyte-binding molecules, (b) a sample well to receive a sample, (c) one or more reagent wells, (d) a plurality of wash wells each containing a first aqueous solution, and (e) a measurement well having a light transmissive bottom, the measurement well containing a second aqueous solution, wherein the openings of the sample well, reagent well, measurement well and wash wells are sealed. The present invention also relates to an apparatus for loading and releasing a probe. The apparatus comprises a push pin and a groove to load and transfer the probe to a plurality of locations, such as different wells in the above-mentioned cartridge, to conduct the immunoassay test.

    Abstract translation: 本发明涉及用于免疫测定试验的药筒。 所述盒包括（a）包括探针和帽的探针孔，所述盖处于关闭位置以将所述探针包围在所述探针中，其中所述探针具有涂覆有分析物结合分子的底部末端，（b） 样品井以接收样品，（c）一个或多个试剂孔，（d）多个洗涤孔，每个洗涤孔含有第一水溶液，和（e）具有透光底部的测量孔，测量孔包含第二 水溶液，其中样品孔，试剂阱，测量井和洗涤井的开口被密封。 本发明还涉及一种用于装载和释放探针的装置。 该装置包括推针和凹槽，以将探针加载并转移到多个位置，例如上述药筒中的不同的孔，以进行免疫测定。

Patent Agency Ranking