公开(公告)号：US20240325645A1

公开(公告)日：2024-10-03

申请号：US18743332

申请日：2024-06-14

Applicant: AMGEN INC.

Inventor： Matias MELANDER ,  Jakob Halkjaer PEDERSEN ,  Christian PLAMBECH ,  Adam B. McCullough ,  Julian JAZAYERI

IPC: A61M5/24 ,  A61M5/20 ,  A61M5/31 ,  A61M5/315 ,  A61M5/32

CPC classification number: A61M5/24 ,  A61M5/3129 ,  A61M5/3148 ,  A61M5/2033 ,  A61M2005/208 ,  A61M2005/2086 ,  A61M2005/3143 ,  A61M5/31585 ,  A61M2005/3267

Abstract: A drug delivery device includes a housing defining a shell having a proximal and a distal end, a needle assembly at least partially disposed within the housing at the proximal end, a drive assembly at least partially disposed within the housing, and a damper mechanism at least partially disposed within the housing adjacent to the distal end. The housing further defines a longitudinal axis extending between the proximal end and the distal end. The needle assembly includes a syringe barrel containing a medicament and a needle or a cannula. The drive assembly is operably coupled to the needle assembly to urge the medicament through the needle or cannula. The damper mechanism is operably coupled to the drive assembly and the housing. Upon activating the drive assembly, the damper mechanism dampens an effect thereof.

公开(公告)号：US20240157057A1

公开(公告)日：2024-05-16

申请号：US18550650

申请日：2022-03-28

Applicant: AMGEN INC.

Inventor： Huixing Jin ,  Julian JAZAYERI ,  Sergio Giovanni VALENZUELA ,  Ryan David SELVE ,  Sivakumar PARAMANANDAM

IPC: A61M5/315 ,  H03K5/01

CPC classification number: A61M5/31568 ,  H03K5/01 ,  A61M2205/3375 ,  A61M2205/702 ,  A61M2209/02

Abstract: A real-time drug injection time duration measurement system includes a sound transducer, a waveform shaping circuit operably coupled therewith, a pulse clamping circuit operably coupled with the waveform shaping circuit, and a timer operably coupled with the pulse clamping circuit. The sound transducer detects a first sound associated with drug delivery initiation and a second sound associated with drug delivery completion and is further converts the detected first and second sounds into a first electronic waveform and a second electronic waveform, respectively. The waveform shaping circuit converts the first and second waveforms into a first pulse and a second pulse, respectively. The pulse clamping circuit triggers upon receiving the first pulse and generate a regenerated pulse. The timer initiates upon receiving the regenerated pulse and stop upon receiving a subsequent regenerated pulse via the pulse clamping circuit.