公开(公告)号：US20240157057A1

公开(公告)日：2024-05-16

申请号：US18550650

申请日：2022-03-28

Applicant: AMGEN INC.

Inventor： Huixing Jin ,  Julian JAZAYERI ,  Sergio Giovanni VALENZUELA ,  Ryan David SELVE ,  Sivakumar PARAMANANDAM

IPC: A61M5/315 ,  H03K5/01

CPC classification number: A61M5/31568 ,  H03K5/01 ,  A61M2205/3375 ,  A61M2205/702 ,  A61M2209/02

Abstract: A real-time drug injection time duration measurement system includes a sound transducer, a waveform shaping circuit operably coupled therewith, a pulse clamping circuit operably coupled with the waveform shaping circuit, and a timer operably coupled with the pulse clamping circuit. The sound transducer detects a first sound associated with drug delivery initiation and a second sound associated with drug delivery completion and is further converts the detected first and second sounds into a first electronic waveform and a second electronic waveform, respectively. The waveform shaping circuit converts the first and second waveforms into a first pulse and a second pulse, respectively. The pulse clamping circuit triggers upon receiving the first pulse and generate a regenerated pulse. The timer initiates upon receiving the regenerated pulse and stop upon receiving a subsequent regenerated pulse via the pulse clamping circuit.