公开(公告)号：US11238150B2

公开(公告)日：2022-02-01

申请号：US16300705

申请日：2017-05-16

Applicant: AMGEN INC.

Inventor： Huaying Yang ,  Andrew Dean ,  Ferry Tamtoro ,  Keng-Tong See ,  Michael Friedman ,  Desheng Yin ,  Huixing Jin ,  Edward Nielsen

IPC: H04K1/00 ,  G06F21/44 ,  G16H20/17 ,  G16H40/40 ,  G06F21/62 ,  H04L9/08 ,  H04L9/14 ,  H04L29/06 ,  G16H40/67 ,  H04W12/03 ,  H04W12/50 ,  H04W12/71

Abstract: A medical device with limited computational capability includes medical hardware, a first register to store a static, substantially unique identifier of the medical device, a second register to store a static encryption key, an interface to receive and transmit data over a short-range communication link, and processing hardware. The processing hardware is configured to apply the static encryption key to the identifier of the medical device to generate an encrypted identifier, transmit the encrypted identifier of to another device via the interface, receive an encrypted identifier of the other device, decrypt the encrypted identifier of the other device using the static encryption key to determine an identifier of the other device, generate a dynamic encryption key using the identifier of the medical device and the identifier of the other device, and apply the dynamic encryption key to medical data transmitted between the medical device and the other device.

公开(公告)号：US20240157057A1

公开(公告)日：2024-05-16

申请号：US18550650

申请日：2022-03-28

Applicant: AMGEN INC.

Inventor： Huixing Jin ,  Julian JAZAYERI ,  Sergio Giovanni VALENZUELA ,  Ryan David SELVE ,  Sivakumar PARAMANANDAM

IPC: A61M5/315 ,  H03K5/01

CPC classification number: A61M5/31568 ,  H03K5/01 ,  A61M2205/3375 ,  A61M2205/702 ,  A61M2209/02

Abstract: A real-time drug injection time duration measurement system includes a sound transducer, a waveform shaping circuit operably coupled therewith, a pulse clamping circuit operably coupled with the waveform shaping circuit, and a timer operably coupled with the pulse clamping circuit. The sound transducer detects a first sound associated with drug delivery initiation and a second sound associated with drug delivery completion and is further converts the detected first and second sounds into a first electronic waveform and a second electronic waveform, respectively. The waveform shaping circuit converts the first and second waveforms into a first pulse and a second pulse, respectively. The pulse clamping circuit triggers upon receiving the first pulse and generate a regenerated pulse. The timer initiates upon receiving the regenerated pulse and stop upon receiving a subsequent regenerated pulse via the pulse clamping circuit.

公开(公告)号：US20220362484A1

公开(公告)日：2022-11-17

申请号：US17767111

申请日：2020-10-05

Applicant: AMGEN INC.

Inventor： Desheng Yin ,  Huixing Jin ,  Huaying Yang ,  Zhuo M. Cai ,  Alireza Ashani

IPC: A61M5/32 ,  A61M5/20 ,  A61M5/315

Abstract: The present disclosure relates to a drug delivery device. The drug delivery device includes a housing having a proximal end and a distal end. Additionally, a needle guard disposed at the proximal end of the housing and movable in an axial direction relative the housing between a first position and a second position. A storage container, disposed within the housing for storing a drug, includes a needle for administering the drug. The drug delivery device also includes an injection activation button disposed on the distal end of the housing and including a fingerprint detector. Additionally, the present disclosure includes a lock configured to switch between a locked configuration inhibiting actuation of the drug delivery device and an unlocked configuration enabling actuation of the delivery device. The lock is in the unlocked configuration when the needle guard is in the second position and the fingerprint detector detects a fingerprint.