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    Addressable plasmonic arrays
    4.
    发明授权
    Addressable plasmonic arrays 有权

    公开(公告)号：US12061147B2

    公开(公告)日：2024-08-13

    申请号：US17619082

    申请日：2020-06-23

    Applicant: University College Dublin, National University of Ireland, Dublin

    Inventor： Dominic Zerulla

    IPC: G01N21/552 ,  G01N21/17 ,  G01N21/64

    CPC classification number: G01N21/553 ,  G01N21/648 ,  G01N2021/1731

    Abstract: An imaging apparatus for imaging a sample (7) comprises an array of electronically addressable pixels (6) wherein each pixel is arranged to support a surface plasmon resonance therein to generate an evanescent electromagnetic field. This field extends transversely from the pixel so as to be salient from the array at a first side of the array for illuminating the sample at said first side. A light source (15) is arranged to illuminate the array with excitation light therewith to generate said surface plasmon resonance. An optical detector (12A, 12B, 12C) is arranged at a second side of the array which is opposite to said first side of the array for detecting optical radiation returned from the array in response to illumination of the array by said excitation light. A processing unit (4) is arranged to associate the detected optical radiation with the address of the pixel or pixels within the array at which the surface plasmon resonance was generated.

    TIERED DATA SHARING PRIVACY ASSURANCE
    8.
    发明公开
    TIERED DATA SHARING PRIVACY ASSURANCE 审中-公开

    公开(公告)号：US20230334168A1

    公开(公告)日：2023-10-19

    申请号：US17720193

    申请日：2022-04-13

    Applicant: University College Dublin ,  Inlecom Group BVBA

    Inventor： Ibad Kureshi ,  Raymond James Genoe ,  Robert Michael Dowdall ,  Cormac James Doherty ,  Antonios Mygiakis

    IPC: G06F21/62

    CPC classification number: G06F21/6245 ,  G06F2221/2101

    Abstract: Embodiments of the present invention provide a method, system and computer program product for tiered data sharing privacy assurance in responding for requests to inspect investigative data. In an embodiment of the invention, a method for tiered data sharing privacy assurance in responding for requests to inspect investigative data includes receiving a request to access investigative data and applying a privacy test to the request to determine if the request is specific for an individual or generic to any individual. On condition that the privacy test is determined to be generic, the request may be denied. But otherwise, on condition the test is determined to be specific, a data sharing rule that defines a degree to which the investigative data is to be shared may be applied and the request responded to according to the defined degree.

    NANOPARTICLE COMPOSITIONS FOR GENE THERAPY
    10.
    发明申请
    NANOPARTICLE COMPOSITIONS FOR GENE THERAPY 有权

    公开(公告)号：US20220340933A1

    公开(公告)日：2022-10-27

    申请号：US17763441

    申请日：2020-09-22

    Applicant: University College Dublin

    Inventor： Wenxin Wang ,  Sigen A ,  Irene Lara-Saez ,  Qian Xu ,  Jonathan O'Keeffe Ahern

    IPC: C12N15/88 ,  C12N15/90 ,  A61K9/51

    Abstract: A nanoparticulate composition comprises a gene editing ribonucleoprotein system complexed within a cationic polymer. The cationic polymer may be a Poly-beta amino ester hyperbranched polymer, especially a 4-branching hyperbranched polymer. The gene editing ribonucleoprotein system may be a CRISPR-Cas9 gene editing system configured to excise a mutation or exon in a gene, replace a mutation in a gene, or produce a knock-down or knock-out of a gene, and in particular configured to excise exon 80 of the COL7A1 gene which codes for the collagen VII protein. Data shows that using

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