公开(公告)号：US08906671B2

公开(公告)日：2014-12-09

申请号：US13532308

申请日：2012-06-25

申请人： Motohiro Yamazaki ,  Ryoji Inaba ,  Shuhei Yamamoto ,  Takuya Matsui ,  Kohshi Maeda ,  Yuichiro Ota ,  Hiroyuki Higashino

发明人： Motohiro Yamazaki ,  Ryoji Inaba ,  Shuhei Yamamoto ,  Takuya Matsui ,  Kohshi Maeda ,  Yuichiro Ota ,  Hiroyuki Higashino

IPC分类号： C12M1/00 ,  C12M3/00 ,  C12M1/34 ,  G01N21/64 ,  G01N21/66 ,  B01L3/00

CPC分类号： B01L3/527 ,  B01L3/523 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2300/045 ,  B01L2300/1894

摘要： A chilled reagent container comprises a reagent vessel containing part for containing therein a plurality of reagent vessels, a container lid including a container lid hole through which the reagent vessels contained by the reagent vessel containing part are accessible, and a cooling block for cooling the reagent vessels contained by the reagent vessel containing part, wherein the container lid slides to be changeable between an opened situation wherein the reagent is accessible from an outside and a closed situation wherein the reagent is prevented from being accessed from the outside, wherein the chilled reagent container further comprises a reagent container packing including another hole through which the reagent vessels are accessible and arranged between the container lid and the reagent vessel containing part to be pressed against the container lid.

摘要翻译： 冷冻试剂容器包括含有多个试剂容器的试剂容器的容纳部，容器盖，其具有可容纳由试剂容器容纳部容纳的试剂容器的容器盖孔，以及用于冷却试剂的冷却块 所述试剂容器容纳部所容纳的容器，其中所述容器盖滑动，其中所述试剂可从外部进入的打开状态和所述试剂被阻止从外部进入的封闭状态之间变化，其中所述冷冻试剂容器 还包括试剂容器填料，其包括另一孔，试剂容器可通过所述孔容纳在容器盖和待压靠在容器盖上的试剂容器容纳部分之间。

公开(公告)号：US08389959B2

公开(公告)日：2013-03-05

申请号：US13147147

申请日：2009-11-30

申请人： Satoshi Takahashi ,  Tsuyoshi Sonehara ,  Tomoyuki Sakai ,  Takanobu Haga ,  Hirokazu Kato ,  Nobutaka Kumazaki ,  Takuya Matsui

发明人： Satoshi Takahashi ,  Tsuyoshi Sonehara ,  Tomoyuki Sakai ,  Takanobu Haga ,  Hirokazu Kato ,  Nobutaka Kumazaki ,  Takuya Matsui

IPC分类号： G01N21/64

CPC分类号： G01N21/648 ,  G01J3/10 ,  G01J3/14 ,  G01J3/36 ,  G01J3/4406 ,  G01N21/6452

摘要： The present invention has an object to provide a method for efficiently detecting an image with a smaller number of pixels.The invention relates to fluorescence analysis which uses a substrate having a plurality of regions for being capable of immobilizing biologically-related molecules in positions of lattice points of a lattice structure, and which causes the fluorescence from a certain lattice point to be wavelength-dispersed in a direction other than the direction toward the adjacent closest lattice point. According to an embodiment, for example, the number of pixels of a two-dimensional sensor required for fluorescence analysis of the regions with the biologically-related molecules immobilized can be set to several hundred times to fifty times smaller than that in the conventional case without degrading the measurement accuracy. This can achieve the improvement of throughput, reduction in price, and/or improvement of the operability of an analyzing device.

摘要翻译： 本发明的目的是提供一种用于有效检测具有较少像素数的图像的方法。 本发明涉及使用具有多个区域的基板的荧光分析，其能够将生物相关分子固定在格子结构的格点的位置，并且使得来自特定格子点的荧光波长分散在 除了朝向相邻最近格子点的方向之外的方向。 根据一个实施例，例如，具有生物相关分子固定的区域的荧光分析所需的二维传感器的像素数量可以设定为比常规情况下少几百次到五十次，而没有 降低测量精度。 这可以实现分析装置的吞吐量的提高，价格的降低和/或改善可操作性。

公开(公告)号：US20120329143A1

公开(公告)日：2012-12-27

申请号：US13532308

申请日：2012-06-25

申请人： Motohiro Yamazaki ,  Ryoji Inaba ,  Shuhei Yamamoto ,  Takuya Matsui ,  Kohshi Maeda ,  Yuichiro Ota ,  Hiroyuki Higashino

发明人： Motohiro Yamazaki ,  Ryoji Inaba ,  Shuhei Yamamoto ,  Takuya Matsui ,  Kohshi Maeda ,  Yuichiro Ota ,  Hiroyuki Higashino

IPC分类号： C12M1/34 ,  G01N21/64 ,  B01L3/00

CPC分类号： B01L3/527 ,  B01L3/523 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2300/045 ,  B01L2300/1894

摘要： A chilled reagent container comprises a reagent vessel containing part for containing therein a plurality of reagent vessels, a container lid including a container lid hole through which the reagent vessels contained by the reagent vessel containing part are accessible, anda cooling block for cooling the reagent vessels contained by the reagent vessel containing part, wherein the container lid slides to be changeable between an opened situation wherein the reagent is accessible from an outside and a closed situation wherein the reagent is prevented from being accessed from the outside, wherein the chilled reagent container further comprises a reagent container packing including another hole through which the reagent vessels are accessible and arranged between the container lid and the reagent vessel containing part to be pressed against the container lid.

摘要翻译： 冷冻试剂容器包括含有多个试剂容器的试剂容器的容纳部，容器盖，其具有可容纳由试剂容器容纳部容纳的试剂容器的容器盖孔，以及用于冷却试剂的冷却块 所述试剂容器容纳部所容纳的容器，其中所述容器盖滑动，其中所述试剂可从外部进入的打开状态和所述试剂被阻止从外部进入的封闭状态之间变化，其中所述冷冻试剂容器 还包括试剂容器填料，其包括另一孔，试剂容器可通过所述孔容纳在容器盖和待压靠在容器盖上的试剂容器容纳部分之间。

公开(公告)号：US20070244096A1

公开(公告)日：2007-10-18

申请号：US11743376

申请日：2007-05-02

申请人： Brian Fox ,  Noboru Furukawa ,  Xiaolin Hao ,  Kiyosei Iio ,  Takashi Inaba ,  Simon Jackson ,  Frank Kayser ,  Marc Labelle ,  Kexue Li ,  Takuya Matsui ,  Dustin McMinn ,  Nobuya Ogawa ,  Steven Rubenstein ,  Shoichi Sagawa ,  Kazuyuki Sugimoto ,  Masahiro Suzuki ,  Masahiro Tanaka ,  Guosen Ye ,  Atsuhito Yoshida ,  Jian Zhang

发明人： Brian Fox ,  Noboru Furukawa ,  Xiaolin Hao ,  Kiyosei Iio ,  Takashi Inaba ,  Simon Jackson ,  Frank Kayser ,  Marc Labelle ,  Kexue Li ,  Takuya Matsui ,  Dustin McMinn ,  Nobuya Ogawa ,  Steven Rubenstein ,  Shoichi Sagawa ,  Kazuyuki Sugimoto ,  Masahiro Suzuki ,  Masahiro Tanaka ,  Guosen Ye ,  Atsuhito Yoshida ,  Jian Zhang

IPC分类号： A61K31/55 ,  A61K31/542 ,  A61K31/5383 ,  C07D497/02 ,  C07D498/02 ,  C07D491/02

CPC分类号： C07D491/04

摘要： Compounds, pharmaceutical compositions and methods that are useful in the treatment or prevention of metabolic and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the activity of proteins involved in lipid metabolism and cell proliferation.

摘要翻译： 本文提供了可用于治疗或预防代谢和细胞增殖性疾病或病症的化合物，药物组合物和方法。 特别地，本发明提供调节参与脂质代谢和细胞增殖的蛋白质的活性的化合物。

公开(公告)号：US20060078948A1

公开(公告)日：2006-04-13

申请号：US11239467

申请日：2005-09-30

申请人： Takuya Matsui ,  Katsuhiro Kanda

发明人： Takuya Matsui ,  Katsuhiro Kanda

IPC分类号： G01N33/542 ,  C12M1/34

CPC分类号： G01N33/54306 ,  G01N33/54393

摘要： An object of the present invention is to provide an analytical method and an analytical instrument with high capability of quantitative determination and reproducibility which can be used for detecting the minor difference between expression levels and measuring the protein concentration, for example. An analytical method for a biological sample is disclosed, wherein two or more labels are present in the same area, and the signal intensity of one specific label is used to normalize the signal intensity of other labels. An analytical instrument, a microarray, and an immunoassay are also disclosed.

摘要翻译： 本发明的目的是提供具有高定量测定和再现性能的分析方法和分析仪器，其可用于检测例如表达水平之间的微小差异和测定蛋白质浓度。 公开了一种用于生物样品的分析方法，其中两个或更多个标签存在于相同的区域中，并且使用一个特定标记的信号强度来标准化其他标签的信号强度。 还公开了分析仪器，微阵列和免疫测定法。

公开(公告)号：US20050011453A1

公开(公告)日：2005-01-20

申请号：US10920180

申请日：2004-08-18

申请人： Tomohiro Okumura ,  Hideo Haraguchi ,  Takuya Matsui ,  Izuru Matsuda ,  Akio Mitsuhashi

发明人： Tomohiro Okumura ,  Hideo Haraguchi ,  Takuya Matsui ,  Izuru Matsuda ,  Akio Mitsuhashi

IPC分类号： C23C16/505 ,  H01J37/32 ,  C23C16/00

CPC分类号： H01J37/32623 ,  C23C16/505

摘要： The interior of a vacuum chamber is maintained at a specified pressure by introducing a specified gas into the vacuum chamber having a plasma trap provided therein. Simultaneously, therewith, evacuation of the chamber is performed by a pump as an evacuating device, and a high-frequency power of 100 MHz is supplied to a counter electrode by counter-electrode use high-frequency power supply. Thus, uniform plasma is generated within the vacuum chamber, where plasma processing such as etching, deposition, and surface reforming can be carried out uniformly with a substrate placed on a substrate electrode.

摘要翻译： 通过将特定的气体引入到其中设置有等离子体阱的真空室中，将真空室的内部保持在特定的压力。 同时，通过作为排气装置的泵进行室的抽真空，并且通过对电极使用的高频电源将100MHz的高频功率提供给对电极。 因此，在真空室内产生均匀的等离子体，其中等离子体处理如蚀刻，沉积和表面重整可以与放置在基板电极上的基板均匀地进行。

公开(公告)号：US06808759B1

公开(公告)日：2004-10-26

申请号：US09511398

申请日：2000-02-23

申请人： Tomohiro Okumura ,  Hideo Haraguchi ,  Takuya Matsui ,  Izuru Matsuda ,  Akio Mitsuhashi

发明人： Tomohiro Okumura ,  Hideo Haraguchi ,  Takuya Matsui ,  Izuru Matsuda ,  Akio Mitsuhashi

IPC分类号： H05H146

CPC分类号： H01J37/32623 ,  C23C16/505

摘要： The interior of a vacuum chamber is maintained at a specified pressure by introducing a specified gas into the vacuum chamber having a plasma trap provided therein. Simultaneously, therewith, evacuation of the chamber is performed by a pump as an evacuating device, and a high-frequency power of 100 MHz is supplied to a counter electrode by counter electrode use high-frequency power supply. Thus, uniform plasma is generated within the vacuum chamber, where plasma processing such as etching, deposition, and surface reforming can be carried out uniformly with a substrate placed on a substrate electrode.

摘要翻译： 通过将特定的气体引入到其中设置有等离子体阱的真空室中，将真空室的内部保持在特定的压力。 同时，通过作为排气装置的泵进行室的抽真空，并且通过对电极使用的高频电源将100MHz的高频功率提供给对电极。 因此，在真空室内产生均匀的等离子体，其中等离子体处理如蚀刻，沉积和表面重整可以与放置在基板电极上的基板均匀地进行。

公开(公告)号：US09393562B2

公开(公告)日：2016-07-19

申请号：US13983340

申请日：2012-01-13

申请人： Takuya Matsui ,  Ryoji Inaba ,  Kazumichi Imai ,  Ryusuke Kimura

发明人： Takuya Matsui ,  Ryoji Inaba ,  Kazumichi Imai ,  Ryusuke Kimura

IPC分类号： C12Q1/68 ,  B01L3/00 ,  B01L3/02 ,  G01N35/10 ,  G01N35/00

CPC分类号： B01L3/502 ,  B01L3/0224 ,  B01L2300/026 ,  B01L2400/0406 ,  C12Q1/6869 ,  G01N35/0098 ,  G01N35/1002 ,  G01N35/1004 ,  G01N35/1095 ,  G01N2035/1039

摘要： Provided is an analyzer capable of reducing the amount of wasted reagents and shortening time required for solution sending, thus increasing throughput for analysis. A microsyringe sucks a minimum required amount of reagent that is substantially the same amount of capacity of a flow cell to a sampling nozzle. Then, the sampling nozzle is inserted into an injection port of the flow cell, and the reagent is injected into the flow cell by driving the microsyringe. The inside of the sampling nozzle is cleaned by moving the sampling nozzle to the cleaning tank and ejecting cleaning water from the sampling nozzle, and the outside of the sampling nozzle is cleaned by spraying cleaning water from an inner wall of the cleaning tank.

摘要翻译： 提供了能够减少试剂浪费量和溶液发送所需时间缩短的分析装置，从而提高分析用量。 微量注射器将最小所需量的试剂吸收到与采样喷嘴相当的流动池的容量基本上相同的量。 然后，将取样喷嘴插入流通池的注入口，通过驱动微量注射器将试剂注入到流通池中。 通过将采样喷嘴移动到清洗槽并从采样喷嘴喷射清洗水来清洁采样喷嘴的内部，并且通过从清洗槽的内壁喷射清洁水来清洁采样喷嘴的外部。

公开(公告)号：US09012256B2

公开(公告)日：2015-04-21

申请号：US13808738

申请日：2011-09-28

申请人： Shinya Nakano ,  Yoshiaki Takeuchi ,  Michio Kondo ,  Takuya Matsui

发明人： Shinya Nakano ,  Yoshiaki Takeuchi ,  Michio Kondo ,  Takuya Matsui

IPC分类号： H01L31/20 ,  H01L31/18 ,  H01L31/0376 ,  H01L31/0747

CPC分类号： H01L31/202 ,  H01L31/03762 ,  H01L31/0747 ,  H01L31/1804 ,  Y02E10/547 ,  Y02P70/521

摘要： A process for producing a photovoltaic device that can improve the power generation characteristics of a solar cell having a heterojunction composed of a p-type crystalline Ge (substrate), an i-type amorphous silicon semiconductor layer, and an n-type amorphous silicon semiconductor layer. A process for producing a photovoltaic device (100) comprising a heterojunction cell (1) prepared by sequentially stacking an i-type amorphous silicon semiconductor layer (12) and an n-type amorphous silicon semiconductor layer (13) on top of a substrate (p-type crystalline Ge (11)), the process comprising a PH3 exposure treatment stage of adjusting the temperature of the substrate (11), from which a surface oxide film has been removed, to a prescribed temperature, and subsequently placing the substrate in a vacuum chamber and exposing the substrate to PH3, an i-layer deposition stage of depositing the i-type amorphous silicon semiconductor layer (12) on the PH3-exposed substrate, an n-layer deposition stage of depositing the n-type amorphous silicon semiconductor layer (13) on the i-type amorphous silicon semiconductor layer (12), and an electrode formation stage of forming electrodes (2, 3, 4) on the surface of the n-type amorphous silicon semiconductor layer, and on the back surface of the substrate (11).

摘要翻译： 一种能够提高具有由p型结晶Ge（基板），i型非晶硅半导体层和n型非晶硅半导体构成的异质结的太阳能电池的发电特性的光电转换装置的制造方法 层。 一种用于制造光电器件（100）的方法，该光电器件（100）包括异质结电池（1），该异质结电池（1）通过将i型非晶硅半导体层（12）和n型非晶硅半导体层（13）依次层叠在基板 p型结晶Ge（11）），该方法包括将表面氧化膜从其中除去的衬底（11）的温度调节到规定温度的PH3曝光处理阶段，然后将衬底置于 真空室，并将衬底暴露于PH3，在暴露于PH3的衬底上沉积i型非晶硅半导体层（12）的i层沉积阶段，沉积n型非晶硅的n层沉积阶段 i型非晶硅半导体层（12）上的半导体层（13），以及在n型非晶硅半导体层的表面上形成电极（2,3,4）的电极形成级，以及背面 表面 的基板（11）。

公开(公告)号：US20130109130A1

公开(公告)日：2013-05-02

申请号：US13808738

申请日：2011-09-28

申请人： Shinya Nakano ,  Yoshiaki Takeuchi ,  Michio Kondo ,  Takuya Matsui

发明人： Shinya Nakano ,  Yoshiaki Takeuchi ,  Michio Kondo ,  Takuya Matsui

IPC分类号： H01L31/20 ,  H01L31/0376

CPC分类号： H01L31/202 ,  H01L31/03762 ,  H01L31/0747 ,  H01L31/1804 ,  Y02E10/547 ,  Y02P70/521

摘要： A process for producing a photovoltaic device that can improve the power generation characteristics of a solar cell having a heterojunction composed of a p-type crystalline Ge (substrate), an i-type amorphous silicon semiconductor layer, and an n-type amorphous silicon semiconductor layer. A process for producing a photovoltaic device (100) comprising a heterojunction cell (1) prepared by sequentially stacking an i-type amorphous silicon semiconductor layer (12) and an n-type amorphous silicon semiconductor layer (13) on top of a substrate (p-type crystalline Ge (11)), the process comprising a PH3 exposure treatment stage of adjusting the temperature of the substrate (11), from which a surface oxide film has been removed, to a prescribed temperature, and subsequently placing the substrate in a vacuum chamber and exposing the substrate to PH3, an i-layer deposition stage of depositing the i-type amorphous silicon semiconductor layer (12) on the PH3-exposed substrate, an n-layer deposition stage of depositing the n-type amorphous silicon semiconductor layer (13) on the i-type amorphous silicon semiconductor layer (12), and an electrode formation stage of forming electrodes (2, 3, 4) on the surface of the n-type amorphous silicon semiconductor layer, and on the back surface of the substrate (11).

摘要翻译： 一种能够提高具有由p型结晶Ge（基板），i型非晶硅半导体层和n型非晶硅半导体构成的异质结的太阳能电池的发电特性的光电转换装置的制造方法 层。 一种用于制造光电器件（100）的方法，该光电器件（100）包括异质结电池（1），该异质结电池（1）通过将i型非晶硅半导体层（12）和n型非晶硅半导体层（13）依次层叠在基板 p型结晶Ge（11）），该方法包括将表面氧化膜从其中除去的衬底（11）的温度调节到规定温度的PH3曝光处理阶段，然后将衬底置于 真空室，并将衬底暴露于PH3，在暴露于PH3的衬底上沉积i型非晶硅半导体层（12）的i层沉积阶段，沉积n型非晶硅的n层沉积阶段 i型非晶硅半导体层（12）上的半导体层（13），以及在n型非晶硅半导体层的表面上形成电极（2,3,4）的电极形成级，以及背面 表面 的基板（11）。