公开(公告)号：US20250034018A1

公开(公告)日：2025-01-30

申请号：US18909776

申请日：2024-10-08

Applicant: Texas Tech University System

Inventor： Gerardine G. BOTTE ,  Eshan ABBASI ,  Christian E. ALVAREZ-PUGLIESE

IPC: C02F11/00 ,  C02F103/20 ,  C02F103/32 ,  C05F3/00 ,  C05F7/00 ,  C05F9/00

Abstract: Methods and systems for pre-treatment of sludge and biosolids in preparation for electrochemical valorization is disclosed herein. Such methods can include selecting a sludge source; preparing a slurry, where the slurry comprises the sludge source and an electrolyte; adjusting a pH of the slurry, where the adjusting the pH of the slurry results in the slurry having an adjusted pH in a range between approximately 8 and 13; flowing the slurry through a first electrochemical cell, where the first electrochemical cell enables partial oxidation of the sludge via hydroxyl radicals; and flowing the partially oxidized slurry from the first electrochemical cell to a second electrochemical cell for selective conversion, where the second electrochemical cell includes an anode, a cathode, and a catalyst.

公开(公告)号：US20250011390A1

公开(公告)日：2025-01-09

申请号：US18712507

申请日：2022-12-02

Applicant: Texas Tech University System

Inventor： Roger B. Sutton ,  Matthew Hirsch

IPC: C07K14/74 ,  A61K38/00 ,  A61P27/02 ,  C12N15/86

Abstract: Provided herein is a fusion protein, expression vector, nucleic acid, or method of making and using a first HLA-G monomer and a second HLA-G monomer connected by a linker peptide expressed as a single chain, and optionally, comprising a providence virus globulin domain to prevent or reduce neovascularization.

公开(公告)号：US20240407712A1

公开(公告)日：2024-12-12

申请号：US18741371

申请日：2024-06-12

Applicant: Texas Tech University System

Inventor： James Yang ,  Ritwik Rakshit

IPC: A61B5/00 ,  A61B5/11 ,  G16H20/30 ,  G16H50/20

Abstract: Embodiments pertain to a computer-implemented method of predicting muscle fatigue in a subject by: (1) receiving data related to muscle fatigue in a muscle of the subject; (2) feeding the data into an algorithm to predict the muscle fatigue; and (3) outputting the predicted muscle fatigue. The algorithm my include: (a) an active compartment (M_A) model representing individual motor units (MUs) generating force at full capacity, (b) a resting compartment (M_R) model representing inactive MUs capable of rapid activation into force production, (c) a centrally fatigued compartment (M_FC) model representing fatigued MUs due to a central mechanism dominant at zero or near-zero joint velocities, with rapid recovery, and (d) a peripherally fatigued compartment (M_FP) model representing fatigued MUs due to a peripheral mechanism dominant at higher velocities, with slow recovery. Further embodiments pertain to a computing device for predicting muscle fatigue in a subject in accordance with such methods.

公开(公告)号：US12134962B2

公开(公告)日：2024-11-05

申请号：US18317621

申请日：2023-05-15

Applicant: Texas Tech University System

Inventor： James J. Sheng

IPC: E21B43/16 ,  E21B47/06

Abstract: Methods for optimization of liquid oil production by huff-n-puff in shale reservoirs to achieve an improved (and optimal) oil recovery factor. The process determines and utilizes the optimum huff and puff times, number of cycles and soaking time under practical operation and reservoir conditions. The huff time in the process is a period so long that the pressure near the wellbore reaches the set maximum injection pressure during the huff period. The puff time in the process is the time required for the pressure near the wellbore to reach the set minimum production pressure during the puff period. Soaking is typically not necessary during the huff-n-puff gas injection in shale oil reservoirs. The number of huff-n-puff cycles is determinable by the time in which the economic rate cut-off is reached.

公开(公告)号：US20240337657A1

公开(公告)日：2024-10-10

申请号：US18744403

申请日：2024-06-14

Applicant: Texas Tech University System

Inventor： Dimitri Pappas

IPC: G01N33/569 ,  B01L3/00 ,  C12Q1/00 ,  G01N33/00 ,  G01N33/543

CPC classification number: G01N33/56972 ,  B01L3/50273 ,  G01N33/54366 ,  G01N33/569 ,  C12Q1/00 ,  G01N33/00

Abstract: Disclosed is a system and method for a microdevice to separate blood cells based on differences in antigen expression. Specifically, cells of the same phenotype are separated based on whether or not they are activated during infection or resting. The device of the present disclosure takes a small sample of blood and provides differential cell counts that can be used to test for infection and inflammatory response. The device can be used to identify sepsis and other infections rapidly. By measuring differences in activated white cell counts such as neutrophils, the device of the present disclosure measures physiological response to infection in hospitalized patients recovering from burns, surgeries, etc.

公开(公告)号：US20240310465A1

公开(公告)日：2024-09-19

申请号：US18608144

申请日：2024-03-18

Applicant: Texas Tech University System

Inventor： David P. Cistola

IPC: G01N33/72

CPC classification number: G01R33/50 ,  G01N33/4925 ,  G01N33/726 ,  G01R33/465

Abstract: Embodiments of the present disclosure pertain to methods of detecting hypoxemia in a subject by: (1) receiving a blood sample from the subject; (2) measuring the T2 relaxation time constant of the blood cell (e.g., blood cell pellet) of the blood sample (T2P value); and (3) correlating the measured T2P value to hypoxemia. In some embodiments, the methods of the present disclosure also include a step of correlating the measured T2P value to the subject's susceptibility to one or more hypoxemia-related conditions. Further embodiments of the present disclosure pertain to systems for detecting hypoxemia in a subject in accordance with the methods of the present disclosure.

公开(公告)号：US12076617B2

公开(公告)日：2024-09-03

申请号：US18542878

申请日：2023-12-18

Applicant: Ballocator LLC ,  Texas Tech University System

Inventor： Dan Fazzini ,  Robert B. Fazzini ,  Steven Johnson ,  Changzhi Li ,  Vishal Gajendrarao Yadav ,  Emmanuel Camacho ,  Rhyse James Ishmael Joseph ,  Leya Zeng

IPC: A63B24/00

CPC classification number: A63B24/0021 ,  A63B2024/0053 ,  A63B2225/54

Abstract: A nonlinear radar system includes a first antenna configured to generate and emit an incident signal having a first frequency, a transponder tag attached to an existing portable object, wherein the transponder tag includes an electromagnetic nonlinear element configured to be detected by the incident signal. Upon being detected by the incident signal, the transponder tag is configured to transmit a reflected return harmonic signal having a second frequency different from the first frequency, wherein the reflected return harmonic signal is an on-off keying (OOK) signal. A second antenna is configured to receive the reflected return harmonic signal having the second frequency. The transponder tag includes a conductive layer in electrical communication with the electromagnetic nonlinear element including a Schottky diode.

公开(公告)号：US12053578B2

公开(公告)日：2024-08-06

申请号：US17911249

申请日：2021-03-16

Applicant: Texas Tech University System

Inventor： Robert V. Duncan ,  Annette L. Sobel ,  Cuikun Lin ,  Christopher Carty ,  Robert Baca ,  Moses Trevor Dardik

IPC: A61M16/00 ,  A61M16/10

CPC classification number: A61M16/0009 ,  A61M16/024 ,  A61M16/109 ,  A61M2016/0027 ,  A61M2205/502 ,  A61M2230/435

Abstract: The present invention includes an apparatus and method for breaking up mucus in a lung comprising: a chamber having an inlet and an outlet; a pressure oscillating unit in fluid communication with the chamber for supplying and vacuuming air into/out of the chamber, wherein the pressure oscillating unit creates ultrasound waves; a control unit for selecting a positive air pressure or a negative air pressure from the pressure oscillating unit, a fluid container in fluid communication with the chamber; a pressure sensor in fluid communication with the chamber; and an outlet connected to the chamber to send respiration gas to a patient, ultrasonic waves in the respiration gas are capable of breaking up mucus in the lung.

公开(公告)号：USD1014898S1

公开(公告)日：2024-02-13

申请号：US29830847

申请日：2022-03-15

Applicant: Texas Tech University System

Designer： Jeffrey L. Hanson ,  Bryan Winn ,  Christopher Sorensen

Abstract: FIG. 1 is a right front perspective view of a motorcycle lift, according to the present invention;
FIG. 2 is a front elevation view of the motorcycle lift of FIG. 1;
FIG. 3 is a rear elevation view of the motorcycle lift of FIG. 1;
FIG. 4 is a left side elevation view of the motorcycle lift of FIG. 1;
FIG. 5 is a right side elevation view of the motorcycle lift of FIG. 1;
FIG. 6 is a top view of the motorcycle lift of FIG. 1; and,
FIG. 7 is a bottom view of the motorcycle lift of FIG. 1.
Broken lines, where present, illustrate portions of the motorcycle lift that form no part of the claimed design.

公开(公告)号：US20240011889A1

公开(公告)日：2024-01-11

申请号：US18037398

申请日：2021-11-19

Applicant: Texas Tech University System

Inventor： Wei LI ,  Zhenya DING

IPC: G01N15/14 ,  B01L3/00

CPC classification number: G01N15/1484 ,  B01L3/502715 ,  G01N15/1434 ,  B01L2300/12 ,  B01L2400/086 ,  B01L2200/0652 ,  G01N2015/1006

Abstract: a hyperuniform-structured microchip is disclosed, which is capable of providing viable resolution of CTC subpopulations supporting the ability to determine whether there is a correlation between CTC heterogeneity and tumor progression.