Reactive thiophosphate derivatives of thia(dia)zole acetic acid and
process for preparing the same
    1.
    发明授权
    Reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same 失效
    硫酸(dia)唑乙酸的活性硫代磷酸酯衍生物及其制备方法

    公开(公告)号:US5502200A

    公开(公告)日:1996-03-26

    申请号:US223756

    申请日:1994-04-06

    摘要: The present invention relates to a novel reactive thiophosphate derivative of thia(dia)zole acetic acid which can be very effectively used in the preparation of .beta.-lactam antibiotics, and which is represented by the following general formula (I): ##STR1## in which R.sup.1 represents hydrogen or an amino-protecting group;R.sup.2 represents hydrogen, C.sub.1 -C.sub.4 alkyl, or --C(R.sup.a)(R.sup.b)CO.sub.2 R.sup.c, wherein R.sup.a and R.sup.b are identical or different from each other and represent hydrogen or C.sub.1 -C.sub.4 alkyl, or R.sup.a and R.sup.b together with a carbon atom to which they are bound can form a C.sub.3 -C.sub.7 cycloalkyl group and R.sup.c is hydrogen or a carboxy-protecting group;R.sup.3 represents C.sub.1 -C.sub.4 alkyl or phenyl or R.sup.3 together with an oxygen atom and a phosphorus atom to which it is bound can form a 5- or 6-membered heterocyclic ring; andQ represents N or CH, and to a process for preparing the same.

    摘要翻译: 本发明涉及一种可以非常有效地用于制备β-内酰胺抗生素的噻唑(dia)唑乙酸的新型反应性硫代磷酸酯衍生物,其由以下通式(I)表示:或氨基 - 保护组 R 2表示氢,C 1 -C 4烷基或-C(R a)(R b)CO 2 R c,其中R a和R b彼此相同或不同,表示氢或C 1 -C 4烷基,或者R a和R b与碳原子一起 它们被结合可以形成C 3 -C 7环烷基,R c是氢或羧基保护基; R3表示C1-C4烷基或苯基或R3与氧原子一起形成与其结合的磷原子可形成5-或6-元杂环; 并且Q表示N或CH,以及其制备方法。

    Solid state image sensing element
    3.
    发明授权
    Solid state image sensing element 失效
    固态摄像元件

    公开(公告)号:US5534720A

    公开(公告)日:1996-07-09

    申请号:US525951

    申请日:1995-09-07

    摘要: A solid state image sensing element including a substrate, photodiode areas each having a plurality of photodiodes in matrix array formed on the substrate, a flat area formed over the substrate including the photodiode areas, color filter layers formed in predetermined areas on the flat area, a top coating layer formed in predetermined areas on the flat area, a top coating layer formed over the substrate including the color filter areas, stripe microlenses each having a flat upper surface arranged to correspond to the photodiodes arranged in one direction in the photodiode areas and formed on the top coating layer, and mosaic microlenses formed on the flat upper surface of the stripe microlens each arranged corresponding to each of the photodiodes in the photodiode area.

    摘要翻译: 一种固体摄像元件,其特征在于,具备:基板,形成在所述基板上的矩阵阵列中的多个光电二极管的光电二极管区域,形成在所述基板上的平坦区域,所述平坦区域包括所述光电二极管区域,所述滤色器层形成在所述平坦区域的规定区域中, 形成在平坦区域上的预定区域中的顶部涂层,形成在包括滤色器区域的基板上的顶部涂层,每个具有布置成对应于在光电二极管区域中沿一个方向布置的光电二极管的平坦上表面的条形微透镜, 形成在顶部涂层上的镶嵌微透镜,以及形成在条形微透镜的平坦上表面上的镶嵌微透镜,每个微透镜对应于光电二极管区域中的每个光电二极管排列。

    Process for preparing cephalosporin compounds from reactive organic acid
derivatives
    7.
    发明授权
    Process for preparing cephalosporin compounds from reactive organic acid derivatives 失效
    从反应性有机酸衍生物制备头孢菌素化合物的方法

    公开(公告)号:US5567813A

    公开(公告)日:1996-10-22

    申请号:US258184

    申请日:1994-06-10

    摘要: The present invention provides a process for preparing cephem derivatives having the following general formula (I): ##STR1## in which R.sup.1 represents a carboxy group or a protected carboxy group which can form the salt of --COO.sup.- M.sup.+ with an alkali metal ion (M.sup.+) such as sodium, or may represent --COO.sup.- when R.sup.2 has a substituent having positive electric charge such as pyridinium, pyrimidinium or thiazolium,R.sup.2 represents hydrogen, acyloxymethyl, heterocyclic methyl or heterocyclic thiomethyl, each of which can be substituted with appropriate substituents,R.sup.3 represents hydrogen or an amino-protecting group,R.sup.4 represents C.sub.1 -C.sub.4 alkyl or phenyl, or together with the oxygen or phosphorus atom to which it is attached may form a 5- or 6-membered heterocyclic ring, andQ represents N or CH, characterized in that a reactive thiophosphate derivative of thia(dia)zole acetic acid having the following general formula (II): ##STR2## wherein R.sup.3, R.sup.4 and Q are defined as above is acylated with an 7-ACA derivative having the following general formula (III): ##STR3## wherein R.sup.1 and R.sup.2 are defined as above, in the presence of a solvent and a base.

    摘要翻译: 本发明提供了具有以下通式(I)的头孢烯衍生物的制备方法:其中R 1表示羧基或保护的羧基,其可与碱形成-COO-M +的盐 金属离子(M +)如钠,或当R2具有正电荷的取代基如吡啶鎓,嘧啶鎓或噻唑鎓时,可以表示-COO-,R2代表氢,酰氧基甲基,杂环甲基或杂环硫甲基,每个可以被取代 具有适当的取代基,R 3表示氢或氨基保护基,R 4表示C 1 -C 4烷基或苯基,或与其连接的氧或磷原子一起形成5-或6-元杂环,Q 表示N或CH,其特征在于具有以下通式(II)的噻唑(dia)唑乙酸的反应性硫代磷酸酯衍生物:其中R 3,R 4和Q如上定义,其中R 7,R 4和Q如上定义,用7 -AC 具有以下通式(III)的衍生物:其中R 1和R 2如上定义,在溶剂和碱的存在下。

    Transparent resin composition radiating far infrared rays
    10.
    发明授权
    Transparent resin composition radiating far infrared rays 失效
    透明树脂组合物辐射远红外线

    公开(公告)号:US5234985A

    公开(公告)日:1993-08-10

    申请号:US915944

    申请日:1992-07-17

    IPC分类号: C08K3/36

    CPC分类号: C08K3/36

    摘要: A far infrared ray radiating transparent resin composition is disclosed. The composition is composed of a transparent resin and a far infrared ray radiating ceramic material. The ceramic material which is added to the resin in the amount of 1-30 weight parts, has an SiO.sub.2 purity of over 96.0%, and an average particle diameter of 0.1-15 .mu.m. The resin composition according to the present invention not only radiates far infrared rays, but also maintains transparency at an acceptable level. Therefore it can be applied to various products where the both transparency and extended freshness of food are required.

    摘要翻译: 公开了一种远红外线辐射透明树脂组合物。 该组合物由透明树脂和远红外线辐射陶瓷材料组成。 以1-30重量份的量添加到树脂中的陶瓷材料的SiO 2纯度高于96.0%,平均粒径为0.1〜15μm。 根据本发明的树脂组合物不仅辐射远红外线,而且将透明度保持在可接受的水平。 因此,它可以应用于需要透明度和延长新鲜度的各种产品。