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    Treatment of tissue in sphincters, sinuses and orifices
    7.
    发明授权
    Treatment of tissue in sphincters, sinuses and orifices 失效
    治疗括约肌，鼻窦和孔的组织

    公开(公告)号：US07022105B1

    公开(公告)日：2006-04-04

    申请号：US09356110

    申请日：1999-07-16

    Applicant: Stuart D. Edwards

    Inventor： Stuart D. Edwards

    IPC: A61M31/00

    CPC classification number: A61N1/06 ,  A61N1/403

    Abstract: The invention provides a method and system for ablation of body structures or tissue in a sphincter, sinus or orifice such as the rectum, colon, esophagus, vagina, penis, larynx or pharynx. In one aspect of the invention, the environment surrounding the targeted ablation region can be isolated or controlled by blocking the flow of gases or liquids using an inflatable balloon positioned immediately adjacent to the tissue that is to be ablated. In a preferred embodiment, the inflatable balloon also serves to anchor the catheter in place and prevent the catheter from being expelled from the body. The inflatable balloon also insures that locally administered drug remain in the area where most needed. In a second aspect of the invention, positive pressure is used to inflate the balloon. Inflation of balloon triggers the extension of at least one curvilinear electrode into the targeted tissue. Negative pressure deflates the air sac and helps retract the curvilinear electrodes so as to allow the catheter to be removed from the body without damaging adjacent body structures. In a third aspect of the invention, the electrodes are coupled to sensors that measure properties of the target region such as temperature and impedance. Measurement of these properties permits the use of feedback technique to control delivery of the RF energy and administration of fluids for cooling and hydrating the affected tissues. In a fourth aspect of the invention, the catheter includes an optical path that can be coupled to external viewing apparatus. In this way, the position of the electrodes in the body can be determined by fluoroscopic or fiber optic techniques.

    Abstract translation: 本发明提供了一种用于消融括约肌，窦或孔如直肠，结肠，食管，阴道，阴茎，喉或咽部中的身体结构或组织的方法和系统。 在本发明的一个方面，围绕目标消融区域的环境可以通过使用紧邻待烧伤组织定位的可充气气囊来阻止气体或液体的流动而被隔离或控制。 在优选实施例中，可膨胀气囊还用于将导管锚定在适当位置并防止导管从身体排出。 充气气囊还确保局部给药的药物保留在最需要的区域。 在本发明的第二方面中，使用正压使气囊膨胀。 球囊的充气触发了至少一个曲线电极延伸到目标组织中。 负压使气囊缩小并帮助缩回曲线电极，以便允许导管从身体移除而不损坏邻近的身体结构。 在本发明的第三方面中，电极耦合到测量目标区域的性质（诸如温度和阻抗）的传感器。 这些性质的测量允许使用反馈技术来控制RF能量的传递和给予流体以冷却和保湿受影响的组织。 在本发明的第四方面中，导管包括可以连接到外部观察装置的光路。 以这种方式，电极在体内的位置可以通过荧光镜或光纤技术来确定。

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