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公开(公告)号：US20220332816A1
公开(公告)日：2022-10-20
申请号：US17621597
申请日：2020-06-22
Applicant: Single Cell Technology, Inc.
Inventor： Leyan TANG , Allison SCHULKINS , Kimberly THAN , Chun-Nan CHEN
IPC: C07K16/28
Abstract: Provided are antibodies that specifically recognize T cell immunoreceptor with Ig and ITIM domains protein (TIGIT).
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公开(公告)号：US09873871B2
公开(公告)日：2018-01-23
申请号：US15050752
申请日：2016-02-23
Applicant: SINGLE CELL TECHNOLOGY, INC.
Inventor： Chun-Nan Chen , James O. Bowlby , Richard Aleck Jorgensen , Mark Jay Shlomchik
CPC classification number: C12N15/1065 , C07K16/2896 , C07K16/40 , C07K2317/56 , G06F19/00 , Y02A90/26
Abstract: The invention is a methodology which makes it possible to select from a very large number of cells, a single cell or cells of interest and obtain specific information from those cells in a rapid and efficient manner. As an example of the methodology, a large number of antibody producing cells such as plasma cells are separated so that these individual antibody producing plasma cells are placed in individual wells. The cells are allowed to produce antibodies and the antibodies in the wells are then contacted with a protein bound to a solid surface such as a well top. The protein universally and specifically binds antibodies in the wells. The surface or well tray top includes addresses configured such that each address is specifically related to one of the individual wells containing a cell producing antibodies.
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公开(公告)号：US20210332145A1
公开(公告)日：2021-10-28
申请号：US17284371
申请日：2019-10-09
Applicant: Single Cell Technology, Inc. , ACROBiosystems, Inc.
Inventor： Leyan TANG , Allison SCHULKINS , Kimberly THAN , Chun-Nan CHEN , Jingyun MIAO , Xiaohui ZHANG , Xiaojuan SHI , Lin ZHANG
Abstract: Provided are antibodies that recognize the B-Cell Maturation Antigen (BCMA) and methods of use thereof.
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4.发明申请METHOD OF SCREENING A PLURALITY OF SINGLE SECRETING CELLS FOR FUNCTIONAL ACTIVITY 有权筛选功能活动单个分泌细胞的多重性的方法公开(公告)号：US20150051098A1
公开(公告)日：2015-02-19
申请号：US14364520
申请日：2012-12-12
Applicant: Single Cell Technology, Inc.
Inventor： Chun-Nan Chen , James O. Bowlby, JR.
IPC: C12Q1/68
CPC classification number: C12Q1/6874 , C12N15/1034 , C12N15/1086 , C40B30/04 , C40B30/06
Abstract: This invention generally relates to methods, devices and kits for screening a plurality of single secreting cells for functional activity of the secreted molecules by measuring the amount of reporter gene mRNA produced in one or more reporter cells in response to the secreted molecules.
Abstract translation: 本发明一般涉及用于通过测量响应于分泌的分子在一个或多个报道细胞中产生的报告基因mRNA的量来筛选多个单个分泌细胞用于分泌分子的功能活性的方法，装置和试剂盒。
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公开(公告)号：US20240059762A1
公开(公告)日：2024-02-22
申请号：US18268192
申请日：2021-12-17
Applicant: Single Cell Technology, Inc.
Inventor： Leyan Tang , Allison Schulkins , Kimberly Than , Chun-Nan Chen
IPC: C07K16/10 , A61P31/14 , C12N15/63 , G01N33/569
CPC classification number: C07K16/1003 , A61P31/14 , C12N15/63 , G01N33/56983 , C07K2317/14 , C07K2317/24 , C07K2317/40 , C07K2317/52 , C07K2317/565
Abstract: Provided are antibodies that specifically recognize SARS-CoV-2 N protein. Also provided are compositions comprising the antibodies and uses thereof.
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Patent Agency Ranking
公开(公告)号：US20230295274A1
公开(公告)日：2023-09-21
申请号：US18017566
申请日：2021-07-27
Applicant: Single Cell Technology, Inc.
Inventor： Leyan Tang , Allison Schulkins , Kimberly Than , Chun-Nan Chen
CPC classification number: C07K16/10 , A61P31/14 , A61K39/42 , A61K45/06 , A61K2039/505
Abstract: Provided are antibodies or antigen binding fragments that specifically recognize a SARS-CoV-2 S protein.
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公开(公告)号：US20220235134A1
公开(公告)日：2022-07-28
申请号：US17613724
申请日：2020-05-27
Applicant: Single Cell Technology, Inc. , ACROBiosystems, Inc.
Inventor： Leyan TANG , Allison SCHULKINS , Kimberly THAN , Chun-Nan CHEN , Jingyun MIAO , Xiaohui ZHANG , Xiaojuan SHI , Lin ZHANG , Pingju GE
Abstract: Provided are antibodies that specifically recognize B7 homology 3 protein (B7-H3).
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公开(公告)号：US20180230534A1
公开(公告)日：2018-08-16
申请号：US15951109
申请日：2018-04-11
Applicant: Single Cell Technology, Inc.
Inventor： Chun-Nan Chen , James O. Bowlby, JR.
IPC: C12Q1/6874 , C12N15/10 , C40B30/06 , C40B30/04
CPC classification number: C12Q1/6874 , C12N15/1034 , C12N15/1086 , C40B30/04 , C40B30/06
Abstract: This invention generally relates to methods, devices and kits for screening a plurality of single secreting cells for functional activity of the secreted molecules by measuring the amount of reporter gene mRNA produced in one or more reporter cells in response to the secreted molecules.
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公开(公告)号：US09944983B2
公开(公告)日：2018-04-17
申请号：US14364520
申请日：2012-12-12
Applicant: Single Cell Technology, Inc.
Inventor： Chun-Nan Chen , James O. Bowlby, Jr.
CPC classification number: C12Q1/6874 , C12N15/1034 , C12N15/1086 , C40B30/04 , C40B30/06
Abstract: This invention generally relates to methods, devices and kits for screening a plurality of single secreting cells for functional activity of the secreted molecules by measuring the amount of reporter gene mRNA produced in one or more reporter cells in response to the secreted molecules.
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公开(公告)号：US20230279105A1
公开(公告)日：2023-09-07
申请号：US17621509
申请日：2020-06-22
Applicant: Single Cell Technology, Inc.
Inventor： Leyan TANG , Allison SCHULKINS , Kimberly THAN , Chun-Nan CHEN
IPC: C07K16/28
CPC classification number: C07K16/2803 , C07K2317/565
Abstract: Provided are antibodies that specifically recognize TIM-3 protein.
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