公开(公告)号：US12203180B2

公开(公告)日：2025-01-21

申请号：US17422328

申请日：2020-01-29

Applicant: PARIS SCIENCES ET LETTRES ,  COLLEGE DE FRANCE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Marc Fontecave ,  Victor Mougel ,  David Wakerley ,  Sarah Lamaison

IPC: C25B11/031 ,  C25B3/03 ,  C25B3/07 ,  C25B3/26 ,  C25B11/042

Abstract: Disclosed are surface modified electrodes, their process of preparation and their use in the electrolytic reduction of carbon dioxide and/or carbon monoxide, as well as an electrochemical cell including the electrode.

公开(公告)号：US20250000428A1

公开(公告)日：2025-01-02

申请号：US18292783

申请日：2022-07-26

Applicant: PARIS SCIENCES ET LETTRES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS ,  NATIONAL INSTITUTE OF HEALTH AND MEDICAL RESEARCH ,  ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS

Inventor： David HOLCMAN ,  Matteo DORA ,  Christophe SUN

IPC: A61B5/374 ,  A61B5/00

Abstract: A computer-implemented method for assisting a general anesthesia or a sedation of a subject, having receiving an electroencephalogram EEG signal of a subject, processing the EEG signal including α-bands for defining for each instant of a plurality of instants, a part of the signal has in a time window having the instant, the part of the signal being related to the instant, determining for each instant, a distribution of a power of the part of the signal as a function of the frequency, determining for each instant a maximum power frequency as a frequency of maximum power in the distribution, the maximum power frequency being related to the instant, detecting a reference instant, so that the maximum power frequency as a function of time takes higher values before the reference instant than after, detecting in a time frame following the reference instant, an alpha instant corresponding to a first occurrence of a suppression of an α-band, estimating a first parameter as the duration between the reference instant and the alpha instant, the first parameter relating to a sensitivity of the subject to a general anesthesia or sedation.

公开(公告)号：US20240288371A1

公开(公告)日：2024-08-29

申请号：US18571139

申请日：2022-06-17

Applicant: PARIS SCIENCES ET LETTRES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  SORBONNE UNIVERSITE ,  UNIVERSITE PARIS SACLAY ,  INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT ,  COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES AL TERNATIVES ,  INSTITUT NATIONAL DES SCIENCES ET INDUSTRIES DU VIVANT ET L'ENVIRONNEMENT

Inventor： Agathe ESPAGNE ,  Klaus BRETTEL ,  Ludovic JULLIEN ,  Thomas LE SAUX ,  Lucie LUDVIKOVA ,  Pavel MÜLLER ,  Lydia ROBERT

IPC: G01N21/64 ,  G02B21/06 ,  G02B21/16

CPC classification number: G01N21/6458 ,  G01N21/6408 ,  G02B21/06 ,  G02B21/16 ,  G01N2021/6419 ,  G01N2201/0231

Abstract: There is provided a method for enhancing the photoresistance of a fluorescent protein when used in fluorescence microscopy of a sample containing several molecules of the fluorescent protein according to a fluorescence microscopy technique. The method includes illuminating at least partially the sample with an exciting light beam and illuminating at least partially the same region of the sample with an enhancing light beam. There is also provided a fluorescence microscopy system suitable to implement the above method.

公开(公告)号：US20240117464A1

公开(公告)日：2024-04-11

申请号：US17768435

申请日：2020-10-16

Applicant: PARIS SCIENCES ET LETTRES ,  ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Frédéric ROUSSEAU ,  Jonathan CRAMER ,  Frédéric PRIMA ,  Daniel MORVAN

IPC: C22B4/00 ,  C22B7/00 ,  H05H1/46

CPC classification number: C22B4/005 ,  C22B7/004 ,  H05H1/4652

Abstract: The invention relates to a process for treating, with a plasma, a composition comprising at least a first compound and a second compound, characterized in that said process comprises at least:



generating, within an enclosure, a non-equilibrium plasma flow from a gas present in said enclosure, and
treating the composition contained in said enclosure with said non-equilibrium plasma flow so as to extract at least a portion of said first compound.

公开(公告)号：US20230416196A1

公开(公告)日：2023-12-28

申请号：US18037331

申请日：2021-11-18

Applicant: INSTITUT CURIE ,  INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  PARIS SCIENCES ET LETTRES

Inventor： RAPHAËL RODRIGUEZ ,  ANTOINE VERSINI ,  TATIANA CAÑEQUE ,  SEBASTIAN MÜLLER ,  STÉPHANIE SOLIER ,  LEEROY BARON

IPC: C07C279/26 ,  A61P35/00

CPC classification number: C07C279/265 ,  A61P35/00

Abstract: The present invention relates to compounds comprising two biguanidyl radicals that can be useful as anti-inflammatory agent, and also to new compounds comprising two biguanidyl radicals and their use as a drug, in particular for treating a cancer, a metabolic disease, a secondary mitochondrial disorder due to copper overload including Indian childhood cirrhosis, Wilson's disease and Idiopathic infantile copper toxicosis or due to iron overload, an infection by a virus such as a coronavirus or an influenza virus, a neurodegenerative disease or disorder and aging.

公开(公告)号：US20230268633A1

公开(公告)日：2023-08-24

申请号：US18018030

申请日：2021-07-20

Applicant: ULTIMETAS ,  PARIS SCIENCES ET LETTRES ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  SORBONNE UNIVERSITE

Inventor： Jean CHAZELAS ,  Charlotte TRIPON-CANSELIET

IPC: H01Q1/06 ,  H01Q1/24 ,  H01Q1/12

CPC classification number: H01Q1/06 ,  H01Q1/1207 ,  H01Q1/24

Abstract: A metasurface device includes an antenna element formed on the front surface of a substrate, the antenna element comprising a two-dimensional array of electrically conductive patches spaced from one another and having dimensions smaller than the operating wavelength of an emission and/or reception device, the antenna element being able to radiate in a direction having a component perpendicular to the front surface of the substrate when the ground structure has a ground plane function, the substrate comprising a layer, called a connection layer, made of photoconductive semiconductor material, in direct physical contact with the conductive patches, the semiconductor material being insulating when it is not illuminated and able to be conductive when it is illuminated at a reconfiguration wavelength.

公开(公告)号：US20230212700A1

公开(公告)日：2023-07-06

申请号：US17917757

申请日：2021-04-09

Applicant: PARIS SCIENCES ET LETTRES ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Patrick TABELING ,  Pierre GARNERET ,  Elian MARTIN ,  Etienne COZ ,  Elodie BRIENT-LITZLER ,  Jean-Claude MANUGUERRA ,  Jessica VANHOMWEGEN

IPC: C12Q1/70 ,  B01L3/00

CPC classification number: C12Q1/701 ,  B01L3/5023 ,  B01L2300/069 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0803 ,  C12Q1/6844

Abstract: A portable diagnostic device for performing the diagnosis of pathogens, such as viruses, bacteria, microorganisms, etc., by rapidly detecting their nucleic acids in a biological sample to be tested. Also, the use of the portable diagnostic device and the methods for detection of at least one nucleic acid sequence of interest implemented with the aid of the portable diagnostic device.

公开(公告)号：US11661662B2

公开(公告)日：2023-05-30

申请号：US16096740

申请日：2017-03-31

Applicant: Paris Sciences et Lettres—Quartier Latin ,  Centre National de la Recherche Scientifique (CNRS) ,  Sorbonne Universite

Inventor： Marc Fontecave ,  Victor Mougel ,  Ngoc Huan Tran

IPC: C25B11/093 ,  C25D7/00 ,  C25D3/38 ,  C25D5/48 ,  C25B11/075 ,  C25B11/077 ,  C25B1/04 ,  H01M4/88 ,  H01M4/90

CPC classification number: C25B11/093 ,  C25B1/04 ,  C25B11/075 ,  C25B11/077 ,  C25D3/38 ,  C25D5/48 ,  C25D7/00 ,  H01M4/8853 ,  H01M4/9041 ,  H01M4/9016 ,  Y02E60/36

Abstract: The present invention relates to an electrode comprising an electrically conductive substrate of which at least one portion of the surface is covered with a metal deposit of copper, the surface of said deposit being in an oxidised, sulphurised, selenised and/or tellurised form and the deposit having a specific surface area of more than 1 m2/g; a method for preparing such an electrode; and a method for oxygenising water with dioxygen involving such an electrode.

公开(公告)号：US20230032722A1

公开(公告)日：2023-02-02

申请号：US17786714

申请日：2020-12-18

Applicant: Paris Sciences et Lettres ,  Centre National de la Recherche Scientifique (CNRS) ,  Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris

Inventor： Viacheslav Mazlin ,  Pedro Francisco Baracal De Mece ,  Albert Claude Boccara

IPC: A61B3/10 ,  A61B5/00

Abstract: A full-field optical coherence tomography imaging method, FFOCT, using a system comprising an FFOCT device and a sample, the sample comprising a layer of interest to be imaged, the FFOCT device comprising an incoherent light source, an imager, a beam splitter defining a sample arm and a reference arm, the method comprising-generating sample light containing interest light originating from the layer of interest and reference light traveling from the reference arm, —acquiring an image from reference light and sample light combined in the beam splitter; wherein at least one of the sample arm and the reference arm comprises an optical curvature compensator that modifies a transverse variation distribution of an optical path length to match the transverse variation distributions of the optical path lengths travelled by the reference light and the interest light incident on the imager.

公开(公告)号：US20230019208A1

公开(公告)日：2023-01-19

申请号：US17785383

申请日：2020-12-18

Applicant: PARIS SCIENCES ET LETTRES ,  Centre National de la Recherche Scientifique ,  École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris ,  Sorbonne Université ,  Université Paris Cité

Inventor： Anke LINDNER ,  Lucie DUCLOUÉ ,  Md. Anamul HAQUE ,  Jian-Ping GONG

IPC: G01L9/00 ,  G01L27/00

Abstract: The present invention relates to microfluidic or millifluidic chips (1) comprising at least one pressure sensing unit (4) able to measure a fluid flow pressure. The present invention also relates to a method for a direct and contact-free measuring of a local pressure of a fluid circulating in a microfluidic circuit, using a microfluidic or millifluidic chips (1) according to the invention.