公开(公告)号：US20240294718A1

公开(公告)日：2024-09-05

申请号：US18573482

申请日：2022-06-22

申请人： SYRACUSE UNIVERSITY ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS

发明人： Joseph PAULSEN ,  Vincent DEMERY

IPC分类号： C08J5/18

CPC分类号： C08J5/18 ,  C08J2325/06

摘要： Thin elastic films that can spontaneously attach to liquid interfaces, thereby offering a platform for tailoring their physical, chemical, and optical properties. Curved shells can be used to manipulate interfaces in qualitatively different ways. For example, an ultrathin shell with vanishing bending rigidity can impose its own rest shape on a liquid surface, in a process where the pressure across the interface inflates the shell into its original shape. The approach is amenable to optical applications as the shell is transparent, free of wrinkles, and may be manufactured over a range of curvatures.

公开(公告)号：US20240228727A1

公开(公告)日：2024-07-11

申请号：US18408255

申请日：2024-01-09

申请人： Protein Evolution Inc. ,  PARIS SCIENCES ET LETTRES ,  Centre National de la Recherche Scientifique ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS ,  SORBONNE UNIVERSITE

发明人： Ludwik Leibler ,  François Tournilhac ,  Clément Freymond ,  Hernan Garate ,  Louise Bréloy ,  Andrew Griffiths ,  Yannick Rondelez ,  Brian Mansaku ,  Jack Pallis ,  Benjamin Gibbs

IPC分类号： C08J11/10

CPC分类号： C08J11/105

摘要： Systems, methods, and compositions relating to pretreatment and enzymatic degradation of polymeric materials comprising one or more crystallizable polymers or copolymers are generally described. Certain aspects are directed to methods comprising reacting a polymeric material comprising a crystallizable polymer or copolymer with a reactive agent to produce a pretreated polymeric material and exposing the pretreated polymeric material to a polymer-degrading enzyme. In some embodiments, the reactive agent induces chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some embodiments, the reactive agent induces chain scissions followed by chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some cases, the methods further comprise a thermal annealing step following the step of reacting the polymeric material comprising the crystallizable polymer or copolymer with the reactive agent and prior to the step of exposing the pretreated polymeric material to the polymer-degrading enzyme. During the thermal annealing step, further chain reactions (e.g., chain scission, extension, branching, and/or cross-linking) may occur.

公开(公告)号：US20240167082A1

公开(公告)日：2024-05-23

申请号：US18550598

申请日：2022-03-18

申请人： PARIS SCIENCES ET LETTRES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS

发明人： Yannick RONDELEZ ,  Andrew GRIFFITHS ,  Gaël BLIVET-BAILLY ,  Pablo IBANEZ ,  Satyam BANERJEE ,  Guillaume GINES ,  Antoine MASURIER

IPC分类号： C12Q1/682 ,  C12N9/12 ,  C12N15/10 ,  C12Q1/6869

CPC分类号： C12Q1/682 ,  C12N9/1241 ,  C12N15/1075 ,  C12N15/1096 ,  C12Q1/6869 ,  C12Q2600/158

摘要： The present invention relates to a method for the selective analysis of a subpopulation of cells or organelles based determining the level of at least one cell or organelle marker, via the implementation of an adapted DNA toolbox able to convert the presence of a cell or organelle marker into a signal. This method is particularly useful for selecting cells or organelles having a phenotype of interest, analyzing the proteins of said cells or organelles and/or sequencing the DNA and/or RNA of said cells. The present invention also relates to a kit for implementing the method of selective analysis of cells or organelles as defined above.

公开(公告)号：US11859150B2

公开(公告)日：2024-01-02

申请号：US16463532

申请日：2017-11-21

申请人： TOTAL MARKETING SERVICES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS

发明人： Thibault Derouineau ,  Fanny Briand ,  Gregory Descroix ,  Renaud Nicolay

IPC分类号： C10M145/14 ,  C08F212/08 ,  C08F220/20 ,  C08L33/06 ,  C08L33/12 ,  C08L35/06 ,  C08F220/18 ,  C08F230/06 ,  C08K5/55

CPC分类号： C10M145/14 ,  C08F212/08 ,  C08F220/1812 ,  C08F220/20 ,  C08F230/06 ,  C08L33/064 ,  C08L33/066 ,  C08L33/12 ,  C08L35/06 ,  C08F220/1818 ,  C08K5/55 ,  C08F220/1818 ,  C08F220/1812 ,  C08F212/08 ,  C08F220/20

摘要： Compositions resulting from the mixing of at least one copolymer A1, resulting from the copolymerization of at least one monomer functionalized by diol functions with at least one styrenic monomer, and at least one compound A2 comprising at least two boronic ester functions. They have very varied rheological properties depending on the proportion of compounds A1 and A2 used. Composition resulting from the mixing of at least one lubricating oil with such a composition of associative and exchangeable polymers and use of this composition for lubricating a mechanical part.

公开(公告)号：US20230309944A1

公开(公告)日：2023-10-05

申请号：US18330502

申请日：2023-06-07

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE ,  SORBONNE UNIVERSITE ,  UNIVERSITÉ PARIS CITÉ ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS ,  ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS

发明人： Jean PROVOST ,  Anikitos GAROFALAKIS ,  Mathieu PERNOT ,  Mickaël TANTER ,  Bertrand TAVITIAN ,  Thomas VIEL

IPC分类号： A61B6/00 ,  A61B6/03 ,  A61B8/06 ,  A61B8/08 ,  A61B8/00 ,  A61N7/00

CPC分类号： A61B6/5247 ,  A61B6/032 ,  A61B6/037 ,  A61B8/06 ,  A61B8/488 ,  A61B6/4258 ,  A61B6/4417 ,  A61B8/4416 ,  A61B8/5261 ,  A61N7/00

摘要： The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a γ-ray, and c) determining the at least one property of the object based on the first data and the second data.

公开(公告)号：US20230275356A1

公开(公告)日：2023-08-31

申请号：US18017852

申请日：2021-07-20

申请人： ULTIMETAS ,  PARIS SCIENCES ET LETTRES ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  SORBONNE UNIVERSITE

发明人： Jean CHAZELAS ,  Charlotte TRIPON-CANSELIET

IPC分类号： H01Q15/00 ,  H01Q3/24 ,  H01Q3/26

CPC分类号： H01Q15/0086 ,  H01Q3/247 ,  H01Q3/2676

摘要： A metasurface device includes a ground structure able to have a ground plane function, the ground structure being able to be alternately in an insulating state, wherein it prevents the propagation of the surface wave over the front surface of a substrate so as to prevent the antenna element from radiating, and in a conductive state, wherein the ground structure has the ground plane function, allowing the propagation of the surface wave over the front surface of the substrate from the emission/reception device to the conductive patches, or vice versa, the ground structure being able to change from the insulating state to the conductive state through illumination of the ground structure at a wavelength called a switching wavelength.

公开(公告)号：US11508261B2

公开(公告)日：2022-11-22

申请号：US15761486

申请日：2016-09-23

申请人： INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  SORBONNE UNIVERSITÉ ,  UNIVERSITÉ PARIS DIDEROT - PARIS 7 ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS

发明人： Thomas Deffieux ,  Mickaël Tanter ,  Jean-Luc Gennisson ,  Zsolt Lenkei ,  Mathieu Pernot

IPC分类号： G09B23/28 ,  A61B8/08 ,  A61B8/00 ,  G16H50/50 ,  A61B8/06 ,  G06T7/00

摘要： The invention relates to a method for obtaining a numerical model, the numerical model associating at least one objective measurement to a subjective sensation, the method comprising the steps of: a) imaging the at least one area of the brain by using unfocused waves produced by a transcranial ultrasound probe (20), to obtain at least one acquired image of the activity of the area, b) evaluating a physical quantity representative of the activity of the at least one area based on the acquired images, to obtain at least one objective measurement, c) obtaining from the subject at least one numerical value representative of a subjective sensation, and d) determining the numerical model by using the obtained objective measurement and the obtained numerical value.

公开(公告)号：US20220227790A1

公开(公告)日：2022-07-21

申请号：US17570040

申请日：2022-01-06

申请人： ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

发明人： Ludwik LEIBLER ,  Renaud NICOLAY

IPC分类号： C07F5/02 ,  C07F7/18

摘要： The invention relates to functionalised dioxaborolane or dioxaborinane derivatives of formula (I), wherein R1 is covalently bonded to the boron atom by a carbon atom; one of R2, R3, R′3 or R4 is a radical of formula —X; or one of R1, R2, R3, R′3 or R4 is a radical of formula —X; and X is a functionalised radical. The invention relates to the method for preparing same and the uses thereof.

公开(公告)号：US11234677B2

公开(公告)日：2022-02-01

申请号：US15580026

申请日：2016-06-09

申请人： Institut National de la Sante et de la Recherche Medicale (INSERM) ,  Centre national de la recherche scientifique ,  Université Pierre et Marie Curie (Paris 6) ,  Université Paris Diderot—Paris 7 ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS

发明人： Jean-Luc Gennisson ,  Mickaël Tanter ,  Thomas Deffieux ,  Mathieu Pernot

IPC分类号： A61B8/00 ,  A61B8/06 ,  A61B5/11 ,  A61B8/08 ,  A61B5/24 ,  A61B5/291

摘要： The invention concerns a detecting apparatus (12) comprising:—at least two sensors (24, 26, 28), with at least one sensor (24) being an ultrasound transducer adapted to produce ultrasound waves, and—a positioning device (16) defining several compartments (22), each compartment (22) being adapted to hold a sensor (24, 26, 28) and each compartment (22) being located at predetermined location, the positioning device (16) comprising a holder adapted to be fixed on the skull of a subject, the positioning device (16) being adapted to be maintained on the head of the subject using the holder.

公开(公告)号：US20210345873A1

公开(公告)日：2021-11-11

申请号：US17280646

申请日：2019-09-27

申请人： PARIS SCIENCES ET LETTRES - QUARTIER LATIN ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) ,  ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS

发明人： Viacheslav Mazlin ,  Peng Xiao ,  Mathias Fink ,  Albert Claude Boccara

IPC分类号： A61B3/10 ,  A61B3/13

摘要： According to one aspect, the invention relates to a system (101) for in vivo, full-field interference microscopy imaging of a scattering three-dimensional sample. It comprises a full-field OCT imaging system (130) for providing en face images of the sample, wherein said full-field OCT system comprises an interference device (145) with an object arm (147) intended to receive the sample and a reference arm (146) comprising an optical lens (134) and a first reflection surface (133), and an acquisition device (138) configured to acquire a temporal succession of two-dimensional interferometric signals (I1, I2) resulting from interferences produced at each point of an imaging field; an OCT imaging system (110) for providing at the same times of acquisition of said two-dimensional interferometric signals, cross-sectional images of both the sample and a first reflection surface (133) of said full-field OCT imaging system (130); a processing unit (160) configured to determine a plurality of en face images (X-Y) of a plurality of slices of the sample, each en face image being determined from at least two two-dimensional interferometric signals (I1, I2) having a given phase shift; determine from the cross-sectional images provided by the OCT imaging system (110) at the times of acquisition of each of said two two-dimensional interferometric signals (I1, I2) a depth (z) for each en face image (X-Y) of said plurality of slices; determine a 3D image of the sample from said plurality of en face images of said plurality of slices of the sample and depths.