公开(公告)号：US20050059931A1

公开(公告)日：2005-03-17

申请号：US10783217

申请日：2004-02-20

Applicant: Michi Garrison ,  Todd Brinton ,  Peter Campbell ,  Steve Roe ,  Stephen Salmon ,  Paul Yock

Inventor： Michi Garrison ,  Todd Brinton ,  Peter Campbell ,  Steve Roe ,  Stephen Salmon ,  Paul Yock

IPC: A61F2/958 ,  A61M25/00 ,  A61M29/00

CPC classification number: A61M25/10 ,  A61M25/0032 ,  A61M25/0054 ,  A61M25/1002 ,  A61M25/1011 ,  A61M2025/0004 ,  A61M2025/1015 ,  A61M2025/105

Abstract: A catheter system for localized or semi-localized administration of agents through the wall of a blood vessel is provided. Various catheter system constructions which use at least one expandable occluding device to create an isolated region are provided. Constructions using one catheter and one occlusion device are provided, along with constructions using two catheters and multiple occlusion devices. The catheter system may include a catheter with a variable stiffness along its length. The catheter system may also include a guide wire integrated with an inner catheter. The catheter can infuse the agent into the blood vessel in a pressure regulated manner. Methods for delivery and infusion of the agent within a blood vessel are also provided.

Abstract translation: 提供了一种用于通过血管的壁局部或半局部施用药剂的导管系统。 提供了使用至少一个可膨胀闭塞装置来产生隔离区域的各种导管系统结构。 提供使用一个导管和一个闭塞装置的结构，以及使用两个导管和多个闭塞装置的构造。 导管系统可以包括沿其长度具有可变刚度的导管。 导管系统还可以包括与内导管一体化的导丝。 导管可以以压力调节的方式将药剂注入血管。 还提供了在血管内递送和输注药剂的方法。

公开(公告)号：US20050059930A1

公开(公告)日：2005-03-17

申请号：US10664171

申请日：2003-09-16

Applicant: Michi Garrison ,  Peter Campbell ,  Steve Salmon

Inventor： Michi Garrison ,  Peter Campbell ,  Steve Salmon

IPC: A61F2/958 ,  A61M25/00 ,  A61M29/00

CPC classification number: A61M25/1011 ,  A61M25/0032 ,  A61M2025/0004 ,  A61M2025/1015 ,  A61M2025/1052

Abstract: A catheter system for localized administration of agents through the wall of a blood vessel is provided. Various catheter system constructions which use at least two expandable occluding elements to create the localized site are provided. The catheter system may include a catheter with a variable stiffness along its length. The catheter system may also include a hollow guide wire which is coupled to an expandable occluding element.

Abstract translation: 提供了一种用于通过血管的壁局部施用药剂的导管系统。 提供了使用至少两个可膨胀闭塞元件来产生局部位置的各种导管系统结构。 导管系统可以包括沿其长度具有可变刚度的导管。 导管系统还可以包括联接到可膨胀闭塞元件的中空导丝。

公开(公告)号：US20060052802A1

公开(公告)日：2006-03-09

申请号：US10941661

申请日：2004-09-15

Applicant: Wesley Sterman ,  Michi Garrison ,  Hanson Gifford ,  John Stevens ,  William Peters

Inventor： Wesley Sterman ,  Michi Garrison ,  Hanson Gifford ,  John Stevens ,  William Peters

IPC: A61B17/06

CPC classification number: A61B17/00234 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/06061 ,  A61B17/064 ,  A61B17/068 ,  A61B17/12013 ,  A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B17/29 ,  A61B17/2909 ,  A61B17/30 ,  A61B17/3403 ,  A61B18/1442 ,  A61B18/1492 ,  A61B90/50 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00637 ,  A61B2017/00663 ,  A61B2017/0243 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/2943 ,  A61B2017/306 ,  A61B2017/3405 ,  A61B2017/3427 ,  A61B2017/3492 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00291 ,  A61B2018/00363 ,  A61B2018/00392 ,  A61B2018/00577 ,  A61B2090/064 ,  A61F2/2427 ,  A61F2/2496 ,  A61M1/3664 ,  A61M25/0023 ,  A61M25/0032 ,  A61M25/1011 ,  A61M39/0247 ,  A61M2025/0003 ,  A61M2025/028 ,  A61M2025/1052 ,  A61M2039/027 ,  A61M2039/0279 ,  A61M2202/047 ,  A61M2205/3344 ,  A61M2205/3355 ,  A61M2205/366 ,  A61M2210/127 ,  A61M2230/005

Abstract: The invention provides devices and methods for performing less-invasive surgical procedures within an organ or vessel. In an exemplary embodiment, the invention provides a method of closed-chest surgical intervention within an internal cavity of a patient's heart or great vessel. According to the method, the patient's heart is arrested and cardiopulmonary bypass is established. A scope extending through a percutaneous intercostal penetration in the patient's chest is used to view an internal portion of the patient's chest. An internal penetration is formed in a wall of the heart or great vessel using cutting means introduced through a percutaneous penetration in an intercostal space in the patient's chest. An interventional tool is then introduced, usually through a cannula positioned in a percutaneous intercostal penetration. The interventional tool is inserted through the internal penetration in the heart or great vessel to perform a surgical procedure within the internal cavity under visualization by means of the scope. In a preferred embodiment, a cutting tool is introduced into the patient's left atrium from a right portion of the patient's chest to remove the patient's mitral valve. A replacement valve is then introduced through an intercostal space in the right portion of the chest and through the internal penetration in the heart, and the replacement valve is attached in the mitral valve position.