摘要:
The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
摘要:
The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1 to R3, A, B, X, and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
摘要:
The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein A1, A2, L1 and B are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorders. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
摘要:
The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
摘要:
The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
摘要:
The present invention provides a method and apparatus for enabling or disabling an ISA adapter or bus expansion device. In one embodiment of the invention, the housing slot is first checked to see whether the device is installed. If the device is installed and is malfunctioning or defective, the device is then isolated or disabled to allow the system to continue to operate. In another embodiment of the invention, a check is done to determine whether the housing slot has changed from an empty to a full status and vice versa. This check determines whether configuration status of an adapter, stored in memory, should be deleted. This check also allows for the differentiation of a PNP adapter card from a legacy adapter card.
摘要:
A method for managing a memory address space in a memory system, the memory system having multiple block address translation entries, each entry defining a portion of the memory address space, including the steps of determining that a received virtual address references a portion of the memory address space not defined by any of the block address translation entries, reallocating at least one of the block address translation entries to define a portion of the memory address space including the received virtual address, and providing a physical address matching the virtual address by using the reallocated block address translation entries. In addition, an apparatus for managing a memory address space in a memory system, the memory system having multiple block address translation entries, each entry defining a portion of the memory address space, including apparatus for determining that a received virtual address references a portion of the memory address space not defined by any of the block address translation entries, apparatus for reallocating at least one of the block address translation entries to define a portion of the memory address space including the received virtual address, and apparatus for providing a physical address matching the virtual address by using the reallocated block address translation entries.
摘要:
The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
摘要:
The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1 to R3, A, B, X, Y and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
摘要:
A memory exhaustion condition is handled in a data processing system having first and second regions of physical memory. The memory exhaustion condition is detected while the second region is mirroring at least part of the first region. In response to the memory exhaustion condition, memory mirroring is at least partially deactivated and at least part of the second region is utilized to augment the first region, such that the memory exhaustion condition is eliminated. In an illustrative embodiment, the data processing system compresses real memory into the first region of physical memory, and the memory exhaustion condition arises when the first region lacks sufficient available capacity to accommodate current requirements for real memory. The memory exhaustion condition is eliminated by compressing at least part of the real memory into the second region.