-
1.发明授权公开(公告)号：US12054335B2
公开(公告)日：2024-08-06
申请号：US18119897
申请日：2023-03-10
发明人： Marc Blomenkemper , Michael Linn , Ronald Hackbarth , Markus Bee
CPC分类号： B65D83/0829 , A61J7/0053 , A61J7/0076 , B65D83/0841 , B65H16/005 , B65H35/0086 , B65H35/0093 , B65H2403/941 , B65H2404/14
摘要： A device for dispensing active ingredient-containing or active ingredient-carrying strips, including a housing in which a coil chamber for receiving an active ingredient-containing or active ingredient-carrying band is arranged, in which a gear transmission with a driven roller for conveying the band is mounted, and in which a separating device for separating the strips from the band is arranged. A method for dispensing active ingredient-containing or active ingredient carrying strips using such a device is also disclosed. An active ingredient-containing or active ingredient-carrying band is arranged between the driven roller and the pressure roller. A shift clutch transmission having a manually actuatable trigger element is arranged upstream of the gear transmission. The driven roller can be driven in incremental strips by the shift clutch transmission. A device and method is disclosed for dispensing active ingredient-containing or active ingredient-carrying strips with a largely equal dosage are developed.
-
公开(公告)号：US12048770B2
公开(公告)日：2024-07-30
申请号：US16755048
申请日：2018-10-11
发明人： Marco Emgenbroich , Eva-Marie Prinz , Elke Klein , Heike Kluth , Xavier Thomas , Linda Sue Nartker
IPC分类号： A61K9/70 , A61K31/155
CPC分类号： A61K9/7084 , A61K9/7069 , A61K31/155
摘要： The present invention relates to a transdermal therapeutic system for the transdermal administration of guanfacine comprising a guanfacine-containing layer structure, said guanfacine-containing layer structure comprising: A) a backing layer; and B) a guanfacine-containing layer; wherein the transdermal therapeutic system comprises at least one silicone acrylic hybrid polymer.
-
公开(公告)号：US20240156726A1
公开(公告)日：2024-05-16
申请号：US18272189
申请日：2022-01-14
发明人： Michael LINN , Mario FICKER , Claudia NORELLI
IPC分类号： A61K9/00 , A61K31/135 , A61K47/10
CPC分类号： A61K9/006 , A61K31/135 , A61K47/10
摘要： The present invention relates to a multi-layer oral thin film comprising a matrix layer, which contains at least one polymer and at least one pharmaceutically active agent, and at least one backing layer, wherein the at least one backing layer comprises at least one polyethylene glycol, to a method for production of the oral thin film, and to the use of such an oral thin film as a medicament.
-
公开(公告)号：US20240148672A1
公开(公告)日：2024-05-09
申请号：US18548690
申请日：2022-03-02
发明人： Markus MÜLLER , Mario FICKER
IPC分类号： A61K31/135 , A61K9/00 , A61K47/32
CPC分类号： A61K31/135 , A61K9/006 , A61K47/32
摘要： The present invention relates to an oral thin film comprising at least one matrix polymer and at least one active pharmaceutical ingredient, wherein the at least one active pharmaceutical ingredient is an acid or a base, characterised in that the at least one active pharmaceutical ingredient is present in the form of a mixture which comprises the at least one active pharmaceutical ingredient both in the form of the free acid or base and in the form of a pharmaceutically acceptable salt, a method for producing said oral thin film, and the use of such an oral thin film as a medicament.
-
公开(公告)号：US20240139098A1
公开(公告)日：2024-05-02
申请号：US18386904
申请日：2023-11-03
发明人： Andreas HENNING , Heiko SPILGIES
CPC分类号： A61K9/0021 , A61K38/26 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/36 , A61M37/0015 , A61M2037/0023
摘要： The present invention relates to a microneedle system (MNS) for intradermal application in a controlled release of glucagon-like peptide analogues.
-
公开(公告)号：US20240130978A1
公开(公告)日：2024-04-25
申请号：US18277679
申请日：2022-02-17
CPC分类号： A61K9/7084 , A61K31/658 , A61K47/10 , A61K47/14 , A61K47/32 , A61K47/34
摘要： Disclosed is a transdermal therapeutic system comprising an active agent impermeable backing layer, at least one adhesive layer comprising at least 70% by weight of at least one polysiloxane polymer, at least one tetrahydrocannabinol (THC) and at least one solubilizer, and optionally a protective layer for removal before use, a method for its preparation and its use as a medicament.
-
公开(公告)号：US20240074969A1
公开(公告)日：2024-03-07
申请号：US18272205
申请日：2022-01-14
发明人： Markus MÜLLER , Mario FICKER , Michael LINN
CPC分类号： A61K9/0056 , A61K47/34
摘要： The present invention relates to a method for producing a multi-layer oral thin film comprising the steps of a) providing a solution, an emulsion, a foam or a suspension comprising at least one first polymer, b) processing the solution, the emulsion, the foam or the suspension from step a) in order to obtain a polymer film, c) applying a powder comprising at least one second substance, which preferably differs from the first polymer, to the polymer film, and d) forming a composite between the polymer film and the powder applied in step c), to a multi-layer oral thin film obtainable by this method, and to the use of a multi-layer oral thin film obtainable by this method as a medicament.
-
公开(公告)号：US20240065974A1
公开(公告)日：2024-02-29
申请号：US18272391
申请日：2022-01-14
发明人： Christoph SCHMITZ , Marius BAUER , Michael LINN
摘要： The present invention relates to an oral thin film comprising a polymer matrix in the form of a solidified foam having voids, wherein the polymer matrix contains at least one active pharmaceutical ingredient, at least one first polymer which comprises a water-soluble polymer and at least one second polymer which comprises a mucoadhesive polymer having a number-average molecular weight of equal to or greater than 100,000 g/mol, a method for producing the oral thin film, and the use of such an oral thin film as a medicament.
-
公开(公告)号：US20240016757A1
公开(公告)日：2024-01-18
申请号：US18365724
申请日：2023-08-04
IPC分类号： A61K9/70 , A61K47/34 , A61K47/02 , A61P21/00 , A61P25/20 , A61P25/00 , A61P25/16 , A61P25/28 , A61P25/22 , A61P25/24 , A61K9/00 , A61K31/381
CPC分类号： A61K9/7069 , A61K47/34 , A61K9/7038 , A61K47/02 , A61P21/00 , A61P25/20 , A61P25/00 , A61P25/16 , A61P25/28 , A61P25/22 , A61P25/24 , A61K9/0014 , A61K31/381
摘要： The present invention relates to aransdermal therapeutic system for the transdermal administration of a systemically active agent having a self-adhesive layer structure. The transdermal therapeutic system includes (A) a backing layer, and (B) a dried biphasic layer. The dried biphasic layer has (a) an outer phase having a composition comprising 75% to 100% of a polymer or polymer mixture, and (b) an inner phase having a composition that includes at least one active agent. The inner phase forms dispersed deposits in the outer phase, with the dried biphasic layer including (c) from 0.1% to 3.5% of an interface mediator other than silicone oil, with the interface mediator having with a kinematic viscosity of from 10 cSt to 100 000 cSt at 25° C.
-
公开(公告)号：US20230285323A1
公开(公告)日：2023-09-14
申请号：US18019505
申请日：2021-07-22
发明人： Florian HAMMES , Anja TOMELERI , Tobias KLEUDGEN
IPC分类号： A61K31/135 , A61K9/70 , A61K47/14 , A61K47/12 , A61K47/10
CPC分类号： A61K31/135 , A61K9/7069 , A61K47/14 , A61K47/12 , A61K47/10
摘要： The present invention concerns a transdermal therapeutic system, comprising a backing layer, which is not permeable N for the active ingredient, and at least one matrix layer on one side of the backing layer, wherein the matrix layer contains at least one pressure sensitive adhesive and ketamine or a pharmaceutically acceptable salt or solvate thereof, wherein the at least one pressure sensitive adhesive comprises a silicone pressure sensitive adhesive, as well as its use as medicament, in particular for the treatment of depression and pain.
-
-
-
-
-
-
-
-
-
搜索结果
283 条记录 (耗时 0.023 秒)
