公开(公告)号：US20250027956A1

公开(公告)日：2025-01-23

申请号：US18711255

申请日：2022-11-17

Applicant: VIB VZW ,  Katholieke Universiteit Leuven

Inventor： Wim Annaert ,  Ragna Sannerud ,  Marine Bretou

IPC: G01N33/68 ,  G01N33/84 ,  G01N33/92

Abstract: Current application relates to the field of neurodegenerative diseases. Specifically, the present invention relates to screening methods to identify therapeutic candidates for the prevention and/or treatment of Alzheimer's disease. More particularly, said candidates overcome endolysosomal dysfunction resulting from an accumulation of APP-carboxyterminal fragments.

公开(公告)号：US20250023503A1

公开(公告)日：2025-01-16

申请号：US18713484

申请日：2022-11-10

Applicant: IMEC VZW ,  Katholieke Universiteit Leuven ,  Kuwait University

Inventor： Raed I H M Bourisli ,  Bader S H M Aldalali ,  Arttu Tuomiranta ,  Mohammed Gofran Chowdhury ,  Jef Poortmans

IPC: H02S20/00 ,  H02S40/42

Abstract: A system comprises at least two photovoltaic modules each comprising a respective module area being substantially perpendicular to the thickness of the corresponding photovoltaic module. Each of the at least two module areas comprises at least one of two first sides being substantially perpendicular to the thickness of the corresponding photovoltaic module and/or two second sides being substantially perpendicular to the thickness of the corresponding photovoltaic module. In this context, the at least two module areas are arranged in a substantially parallel manner with respect to each other and are shifted with respect to each other in an extension direction of the system. In addition to this, the at least two module areas are arranged in a staggering or alternating or ascending or descending manner with respect to an extension plane in the extension direction of the system.

公开(公告)号：US12194497B2

公开(公告)日：2025-01-14

申请号：US18589696

申请日：2024-02-28

Applicant: IMEC VZW ,  Katholieke Universiteit Leuven

Inventor： David Cheyns ,  Yongbin Jeong ,  Xavier Rottenberg

IPC: B06B1/06 ,  B06B1/02 ,  A61B8/00

Abstract: The present invention provides a flexible ultrasound transducer for an ultrasound monitoring system for examining a curved object. The ultrasound transducer comprises an integrated circuit structure and a multi-layered structure, said multi-layered structure comprising an array of ultrasound transducing elements arranged in a first layer structure and configured for generating ultrasonic energy propagating along a main transducer axis Z and an array of control circuits arranged in a second layer structure, and wherein the array of control circuits and the integrated circuit structure are configured for operating the array of ultrasound transducing elements in said first layer structure, Further, the multi-layered structure comprises at least one flexible layer arranged so that the bending flexibility of the multi-layered structure permits the ultrasound transducer to form a continuous contact with said curved object during operation.

公开(公告)号：US20240376149A1

公开(公告)日：2024-11-14

申请号：US18683030

申请日：2022-08-16

Applicant: VIB VZW ,  Katholieke Universiteit Leuven ,  Vrije Universiteit Brussel

Inventor： Joris De Wit ,  Ana Rita Santos ,  Joao Carvalho ,  Laurent Galibert ,  Inge Van Molle ,  Han Remaut ,  Sylvain Celanire

IPC: C07K7/06 ,  A61K38/00 ,  A61P25/00

Abstract: The present invention relates to the field of disorders of the central and peripheral nervous system, in particular neurological and psychiatric disorders, and the prevention and/or treatment thereof. In particular, the present invention relates to the finding that short peptides derived from the soluble amyloid precursor protein α (sAPPα) bind and modulate GABABR1a. The peptides are provided for clinical use, more particularly for the treatment of neurological diseases such as CMT as well as for psychiatric disorders.

公开(公告)号：US20240373617A1

公开(公告)日：2024-11-07

申请号：US18654367

申请日：2024-05-03

Applicant: IMEC VZW ,  Katholieke Universiteit Leuven

Inventor： Hsiao-Hsuan Liu ,  Boon Teik Chan ,  Shairfe Muhammad Salahuddin

IPC: H10B10/00

Abstract: A three-dimensional (3D) static random access memory (SRAM) cell includes two PU transistors arranged in a first tier, two PD transistors arranged in a second tier positioned above or below the first tier, and two PG transistors arranged in the first or second tier. The transistors can be fin transistors, and each PU and PD transistor can have a first and second number of fins, respectively. The transistors can also be nanosheet-based transistors, and each PU and PD transistor can have a first and a second nanosheet width, respectively.

公开(公告)号：US20240367377A1

公开(公告)日：2024-11-07

申请号：US18293841

申请日：2022-08-01

Applicant: KATHOLIEKE UNIVERSITEIT LEUVEN

Inventor： Jie ZHANG ,  Eleonora FERRARIS ,  Fankai MENG ,  Loren DE VOGELAER ,  Maarten VANIERSCHOT

IPC: B29C64/295 ,  B29C64/118 ,  B33Y10/00 ,  B33Y30/00

Abstract: A liquefier assembly for use in an extrusion-based additive manufacturing apparatus, includes: a liquefier tube extending between an inlet opening and an outlet opening. The liquefier tube is configured to facilitate the transport of the consumable material through the liquefier assembly between the inlet opening and the outlet opening. A nozzle assembly is coupled to the outlet opening of the liquefier tube and configured to extrude the consumable material in a first direction. A heater block assembly is disposed around at least a portion of the liquefier tube and configured to heat consumable material in the liquefier tube. The first recess exhibits, in section, at least one boundary edge configured to converge thermal radiation in substantially the first direction or a direction having an angle to the first direction.

公开(公告)号：US20240337743A1

公开(公告)日：2024-10-10

申请号：US18395867

申请日：2023-12-26

Applicant: IMEC VZW ,  Katholieke Universiteit Leuven

Inventor： Adham SAKHNINI ,  Andre BOURDOUX

IPC: G01S13/42 ,  G01S7/00 ,  G01S13/00

CPC classification number: G01S13/42 ,  G01S7/006 ,  G01S13/003

Abstract: A method for use in radar processing, comprises processing a radar signal captured by a radar receiver, said processing comprising determining, for a scattering object a direction of departure from a radar transmitter to said scattering object; and a direction of arrival at said radar receiver from said scattering object; and calculating a position of said scattering object based on said direction of arrival; said direction of departure; and predetermined position and orientation information of said radar transmitter in relation to said radar receiver, whereby said calculating of said position of said scattering object is unbiased by a time synchronization offset between said radar transmitter and said radar receiver.

公开(公告)号：US20240315259A1

公开(公告)日：2024-09-26

申请号：US18272752

申请日：2022-01-20

Applicant: Universiteit Gent ,  Katholieke Universiteit Leuven

Inventor： Danny GEELEN ,  Bruno CAMMUE ,  Geert HAESAERT ,  Tina KYNDT

IPC: A01N65/44 ,  A01P1/00 ,  A01P3/00 ,  A01P5/00 ,  B01D11/02 ,  C12F3/00

CPC classification number: A01N65/44 ,  A01P1/00 ,  A01P3/00 ,  A01P5/00 ,  B01D11/0288 ,  C12F3/00

Abstract: The present invention relates to the use of a Distillers' Dried Grains with Solubles (DDGS) as a biopesticide and/or biostimulant in agriculture.

公开(公告)号：US20240309313A1

公开(公告)日：2024-09-19

申请号：US18577903

申请日：2022-07-07

Applicant: VIB VZW ,  Katholieke Universiteit Leuven ,  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

Inventor： Kevin Verstrepen ,  Ping-Wei Ho ,  Dan Jarosz

IPC: C12N1/18 ,  A61K36/064 ,  C12N9/22 ,  C12N15/11 ,  C12N15/81 ,  C12P7/16 ,  C12P7/54 ,  C12R1/865

CPC classification number: C12N1/185 ,  A61K36/064 ,  C12N9/22 ,  C12N15/111 ,  C12N15/81 ,  C12P7/16 ,  C12P7/54 ,  C12N2310/20 ,  C12R2001/865

Abstract: The present invention relates to the field of yeast fermentations. More particularly, the invention relates to mutant alleles useful to engineer industrially relevant traits in yeast.

公开(公告)号：US20240309168A1

公开(公告)日：2024-09-19

申请号：US18575918

申请日：2022-07-01

Applicant: KATHOLIEKE UNIVERSITEIT LEUVEN

Inventor： Wim THIELEMANS ,  Jose Jonathan RUBIO ARIAS

IPC: C08J11/16

CPC classification number: C08J11/16 ,  C08J2367/02 ,  C08J2369/00 ,  C08J2377/00

Abstract: In accordance with the purpose of the invention, as embodied and broadly described herein, the invention is broadly drawn to the use of an alcoholic medium, for instance methanol medium with an alkaline, for instance an alkali hydroxide, as depolymerization agent without any further addition of organic solvents under microwave action (heating) to achieve almost instantaneous, for instance within 1-13 minutes, for almost 100%, for instance 98-99, 9%, depolymerization of polyethylene terephthalate structures or polycarbonate structures of any suitable shape and morphology such as flakes, fibers, powder, sheet, pellet, spheres, pearls, dendrites, discs or any other three-dimensional shape with a micrometric or millimetric dimension, singly or in combination if these are millinized structures, microsized structures, structures having a thickness up to 5 mm or structures having a maximum dimension of not more than 10 mm.