IL-18 Receptors
    3.
    发明申请
    IL-18 Receptors 失效
    IL-18受体

    公开(公告)号:US20100190211A1

    公开(公告)日:2010-07-29

    申请号:US12716993

    申请日:2010-03-03

    IPC分类号: C12P21/06 C12N5/10

    摘要: A novel polypeptide that functions as an IL-18 receptor is disclosed. The receptor is multimeric and includes at least one AcPL polypeptide, or fragment thereof, and at least one IL-1Rrp1 polypeptide, or fraction thereof. The receptor binds IL-18 and finds use in inhibiting biological activities mediated by IL-18.

    摘要翻译: 公开了用作IL-18受体的新型多肽。 受体是多聚体并且包括至少一个AcPL多肽或其片段,以及至少一种IL-1Rrp1多肽或其部分。 受体结合IL-18,可用于抑制IL-18介导的生物活性。

    IL-18 receptors
    4.
    发明授权
    IL-18 receptors 失效
    IL-18受体

    公开(公告)号:US07704945B2

    公开(公告)日:2010-04-27

    申请号:US11699676

    申请日:2007-01-29

    IPC分类号: A61K38/00 A61K38/20

    摘要: A novel polypeptide that functions as an IL-18 receptor is disclosed. The receptor is multimeric and includes at least one AcPL polypeptide, or fragment thereof, and at least one IL-1Rrp1 polypeptide, or fraction thereof. The receptor binds IL-18 and finds use in inhibiting biological activities mediated by IL-18.

    摘要翻译: 公开了用作IL-18受体的新型多肽。 受体是多聚体并且包括至少一个AcPL多肽或其片段,以及至少一种IL-1Rrp1多肽或其部分。 受体结合IL-18,可用于抑制IL-18介导的生物活性。

    METHODS OF TREATING INFLAMMATORY DISORDERS OF THE LUNGS
    5.
    发明申请
    METHODS OF TREATING INFLAMMATORY DISORDERS OF THE LUNGS 失效
    治疗肺炎的炎症病症的方法

    公开(公告)号:US20100080804A1

    公开(公告)日:2010-04-01

    申请号:US12604289

    申请日:2009-10-22

    IPC分类号: A61K39/395 A61P29/00

    CPC分类号: C07K14/705 A61K38/00

    摘要: 2F1 polypeptides are provided, along with DNA sequences, expression vectors and transformed host cells useful in producing the polypeptides. Soluble 2F1 polypeptides find use in inhibiting prostaglandin synthesis and treating inflammation.

    摘要翻译: 提供2F1多肽以及DNA序列,表达载体和可用于产生多肽的转化的宿主细胞。 可溶性2F1多肽用于抑制前列腺素的合成和治疗炎症。

    IL-1 eta DNA and polypeptides
    7.
    发明授权
    IL-1 eta DNA and polypeptides 失效
    IL-1 eta DNA和多肽

    公开(公告)号:US07223565B2

    公开(公告)日:2007-05-29

    申请号:US10843189

    申请日:2004-05-10

    CPC分类号: C07K14/545

    摘要: The invention is directed to novel, purified and isolated IL-1 eta polypeptides and fragments thereof, the polynucleotides encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, peptides derived from these polypeptides, and uses thereof.

    摘要翻译: 本发明涉及新颖的,纯化和分离的IL-1 eta多肽及其片段,编码此类多肽的多核苷酸,产生此类多肽的重组形式的方法,针对这些多肽产生的抗体,衍生自这些多肽的肽及其用途 。

    Human IL-1 epsilon DNA and polypeptides
    8.
    发明授权
    Human IL-1 epsilon DNA and polypeptides 失效
    人IL-1εDNA和多肽

    公开(公告)号:US06949359B1

    公开(公告)日:2005-09-27

    申请号:US09763498

    申请日:1999-08-20

    CPC分类号: C07K14/545 A61K38/00

    摘要: The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in cellular and immune reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, and kits comprising these reagents.

    摘要翻译: 本发明涉及纯化和分离的新型人IL-1ε-多肽,编码此类多肽的核酸,生产此类多肽的重组形式的方法,针对这些多肽产生的抗体,衍生自这些多肽的片段化肽,使用这些多肽 细胞和免疫反应中的多肽和片段肽以及分子量标记,使用这些多肽和片段肽作为肽断裂的对照,以及包含这些试剂的试剂盒。