摘要:
The present invention relates to a composition for enhancing an immune response, an epitope having immunogenicity, screening and preparing method thereof, a antibody to peptide antigen and screening and preparing method thereof. The composition of the present invention may be effectively used for preventing or treating diverse immune-deficiency diseases such as cancer, influenza virus, hepatitis C virus and RSV (respiratory syncytial virus) by enhancing immune responses.
摘要:
Disclosed is a foldable cross-patterned pull-handle and a bag having the same. The pull-handle includes a folding means having a first link assembly and a second link assembly connected to an end of the first link assembly so that the folding means can be folded and retracted or unfolded and extended, the first link assembly having two links connected to each other so that the links cross each other at a center portion, a first end of the second link assembly being supported on a bag; and a handle means mounted on a second end of the folding means and grabbed by a user with hand. Due to the structural characteristics of the link assemblies constituting the folding means, the length of the bag handle can be adjusted variously by folding or unfolding it, and the bag handle can be installed in a reduced space.
摘要:
Disclosed is the therapeutic use of CpG oligodeoxynucleotides for skin diseases. The CpG oligodeoxynucleotides (CpG ODNs) of the present invention show excellent immunoactive effects against skin diseases in both cases of CpG ODNs with a phosphorothioate backbone and CpG ODNs with a phosphodiester backbone.
摘要:
Disclosed are oligonucleotides for manipulating an immune reaction. The oligonucleotides of the present invention may be useful to stimulate the immune function, to treat the immune-related diseases and the atopic dermatitis, or to protect the normal immune cells.
摘要:
The present invention relates to a novel endonuclease enzyme which is secreted from immune cell and recognizes bacterial DNA as foreign agent and processes it to produce about 10 bp single-stranded oligonucleotide including CpG motif which is involved in immune response. Also, the present invention relates to a process for producing the endonuclease which comprises culturing human B-lymphoblastic IM9 cell line or TPA-treated myelogenous U937 cell line on an appropriate medium to produce the said endonuclease and isolating the said endonuclease from the cell lysate or the culture medium. In addition, the present invention relates to an immune adjuvant comprising about 10 bp single-stranded oligonucleotide having CpG motif produced by treatment of bacterial DNA by endonuclease.
摘要:
Disclosed is a bag having a handle unit with improved precision of an extendable length. The bag includes a body and a handle unit mounted on one side of the body. The handle unit includes a housing coupled with one side of the body and having an installation space therein, a foldable section arranged in the installation space and having a configuration in which a plurality of links cross each other such that the plurality of links are extended and contracted in folded or unfolded states, a lock gear section that fixes an extendable length of the foldable section and is coupled to an upper end of the foldable section to reduce tolerance occurring when the foldable section is extended and contracted, and a lock gear adjustment section that adjusts driving of the lock gear section such that the foldable section.
摘要:
Disclosed is a fusion protein containing a FK506 binding protein and a cell-transducing domain. Also, disclosed is a method of making the fusion protein and use of the fusion protein in a pharmaceutical or cosmetic composition. The cell-transducing domain is, for example, a PEP-1.
摘要:
The present invention relates to a composition for enhancing an immune response, an epitope having immunogenicity, screening and preparing method thereof, a antibody to peptide antigen and screening and preparing method thereof. The composition of the present invention may be effectively used for preventing or treating diverse immune-deficiency diseases such as cancer, influenza virus, hepatitis C virus and RSV (respiratory syncytial virus) by enhancing immune responses.
摘要:
Disclosed is the therapeutic use of CpG oligodeoxynucleotides for skin diseases. The CpG oligodeoxynucleotides (CpG ODNs) of the present invention show excellent immunoactive effects against skin diseases in both cases of CpG ODNs with a phosphorothioate backbone and CpG ODNs with a phosphodiester backbone.
摘要:
Disclosed are oligonucleotides for manipulating an immune reaction. The oligonucleotides of the present invention may be useful to stimulate the immune function, to treat the immune-related diseases and the atopic dermatitis, or to protect the normal immune cells.