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    Endonuclease of immune cell, process for producing the same and immune adjuvant using the same
    1.
    发明授权
    Endonuclease of immune cell, process for producing the same and immune adjuvant using the same 失效
    免疫细胞的内切核酸酶，其制备方法和使用其的免疫佐剂

    公开(公告)号：US06881561B1

    公开(公告)日：2005-04-19

    申请号：US09722776

    申请日：2000-11-27

    Applicant: Doo Sik Kim ,  Hyung Joo Kwon

    Inventor： Doo Sik Kim ,  Hyung Joo Kwon

    IPC: C12N9/22 ,  C12N9/00 ,  C07K1/00 ,  C12N9/14

    CPC classification number: C12N9/22

    Abstract: The present invention relates to a novel endonuclease enzyme which is secreted from immune cell and recognizes bacterial DNA as foreign agent and processes it to produce about 10 bp single-stranded oligonucleotide including CpG motif which is involved in immune response. Also, the present invention relates to a process for producing the endonuclease which comprises culturing human B-lymphoblastic IM9 cell line or TPA-treated myelogenous U937 cell line on an appropriate medium to produce the said endonuclease and isolating the said endonuclease from the cell lysate or the culture medium. In addition, the present invention relates to an immune adjuvant comprising about 10 bp single-stranded oligonucleotide having CpG motif produced by treatment of bacterial DNA by endonuclease.

    Abstract translation: 本发明涉及从免疫细胞分泌并识别细菌DNA作为外来试剂的新型内切核酸酶，并将其处理以产生约10bp的单链寡核苷酸，包括参与免疫应答的CpG基序。 此外，本发明涉及生产内切核酸酶的方法，其包括在合适的培养基上培养人B淋巴细胞IM9细胞系或TPA处理的骨髓瘤U937细胞系以产生所述内切核酸酶并从细胞裂解物中分离所述内切核酸酶或 培养基。 此外，本发明涉及包含通过内切核酸酶处理细菌DNA产生的具有CpG基序的约10bp单链寡核苷酸的免疫佐剂。

    SYSTEM AND METHOD FOR LINKING E-MAIL ADDRESS WITH POSTAL ADDRESS
    5.
    发明申请
    SYSTEM AND METHOD FOR LINKING E-MAIL ADDRESS WITH POSTAL ADDRESS 审中-公开
    用于将电子邮件地址与邮政地址相连接的系统和方法

    公开(公告)号：US20100057486A1

    公开(公告)日：2010-03-04

    申请号：US12354065

    申请日：2009-01-15

    Applicant: Ho Yon Kim ,  Doo Sik Kim ,  Jong Heung Park

    Inventor： Ho Yon Kim ,  Doo Sik Kim ,  Jong Heung Park

    IPC: G06Q10/00

    CPC classification number: G06Q10/107 ,  G06Q10/10

    Abstract: The present invention relates to a linkage system and a linkage method that links an e-mail address with a postal address. The present invention relates to a system and a method that delivers a postal item to a real address of a customer corresponding to an e-mail address, even though the e-mail address is entered in the postal item. According to the present invention, since the e-mail address and the postal address are linked with each other, even if the user's residence is changed, the changed address can be confirmed by using the e-mail address that is linked with the postal address. Accordingly, it is possible to prevent the loss of the postal item. In addition, since a semi-permanent e-mail address is used instead of the postal address, which often changes, in a communication way between individuals, a sender can send the postal item by using only the e-mail address without worrying about the address change of recipient, even when not knowing the address of the recipient.

    Abstract translation: 本发明涉及将电子邮件地址与邮政地址相链接的联动系统和联动方法。 本发明涉及一种将邮件递送到与电子邮件地址相对应的客户的真实地址的系统和方法，即使该邮件地址被输入邮政物品。 根据本发明，由于电子邮件地址和邮政地址彼此链接，所以即使改变了用户的住所，也可以通过使用与邮政地址相连的电子邮件地址来确认变更的地址 。 因此，可以防止邮件丢失。 另外，由于使用半永久的电子邮件地址而不是通常以个人之间的通信方式改变的邮政地址，发件人可以仅使用电子邮件地址来发送邮件，而不用担心 即使不知道收件人的地址，也可以改变收件人的地址。

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