公开(公告)号：US06197994B1

公开(公告)日：2001-03-06

申请号：US09304593

申请日：1999-05-04

申请人： Choong Eui Song ,  Jung Woon Yang

发明人： Choong Eui Song ,  Jung Woon Yang

IPC分类号： C07C6976

CPC分类号： C07C29/48 ,  C07B2200/07 ,  C07C67/31 ,  C07C2601/14 ,  C07C69/732 ,  C07C33/26 ,  C07C35/21

摘要： The present invention relates to silica gel supported bis-cinchona alkaloid compounds of the formula: wherein Q is dihydroquininyl or dihydroquinindinyl; X is a compound having 4 carbon atoms; and R is methoxy, ethoxy or methyl; and methods of preparation and use thereof. The silica gel supported bis-cinchona alkaloid derivatives of this invention are useful re-useable catalysts for preparing vicinal diols by asymmetric dihydroxylation of olefins.

摘要翻译： 本发明涉及下式的硅胶负载的双 - 焦虑激素生物碱化合物：其中Q是二氢喹啉或二氢喹啉基; X是具有4个碳原子的化合物; R为甲氧基，乙氧基或甲基; 及其制备和使用方法。 本发明的硅胶负载双螯合生物碱衍生物是通过烯烃的不对称二羟基化制备连环二醇的有用的可再用催化剂。

公开(公告)号：US5103065A

公开(公告)日：1992-04-07

申请号：US630173

申请日：1990-12-19

申请人： Werner Bertleff ,  Dieter Koeffer ,  Wolfgang Klaeui ,  Choong-Eui Song

发明人： Werner Bertleff ,  Dieter Koeffer ,  Wolfgang Klaeui ,  Choong-Eui Song

IPC分类号： B01J31/22 ,  B01J31/16 ,  B01J31/18 ,  C07B61/00 ,  C07C1/00 ,  C07C2/48 ,  C07C5/03 ,  C07C5/08 ,  C07C13/18 ,  C07C45/00 ,  C07C45/50 ,  C07C47/02 ,  C07C67/00 ,  C07C67/347 ,  C07C69/76 ,  C07F15/00 ,  C07F15/06

CPC分类号： C07F15/06 ,  B01J31/1845 ,  B01J31/185 ,  B01J31/2295 ,  C07C2/48 ,  C07C45/50 ,  C07C5/03 ,  C07C5/08 ,  C07F15/0006 ,  C07F15/0046 ,  C07F15/0073 ,  B01J2231/321 ,  B01J2231/328 ,  B01J2231/645 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/827 ,  B01J2531/845 ,  C07C2531/22

摘要： Transition metal complexes of the general formula I[A].sup.x- [Q].sup.+ x Iwhere Q is one equivalent of a cation, x is from 0 to 2 and A is a transition metal complex of the general formula ##STR1## where n is from 1 to 3, M is positively charged cobalt, rhodium, iridium or ruthenium, the ligands B are phosphonic, arsonic, phosphinic and/or arsinic acid ligands which are esterified with identical or different alcohols, one or more of these alcohol components carrying a functional group, L is ##STR2## the radicals R.sup.5 are identical or different radicals from the group consisting of C.sub.1 -C.sub.4 -alkyl and phenyl, p is an integer from 0 to 6, q is an integer from 0 to 5, and R.sup.1 is fluorine, chlorine, bromine, iodine, cyanide, isocyanide, cyanate, isocyanate, thiocyanate, isothiocyanate, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -trialkyl phosphite or triaryl phosphite, are used as catalysts, or prepared in situ, in processes for the cyclotrimerization of acetylene compounds, for the catalytic hydrogenation of unsaturated compounds and for the hydroformylation of alkenes.

公开(公告)号：US20110213151A1

公开(公告)日：2011-09-01

申请号：US13008793

申请日：2011-01-18

申请人： Choong Eui SONG ,  Sang Ho OH ,  Ho Sik RHO ,  Ji Woong LEE ,  Je Wun LEE ,  Sung Hoon YOUK ,  Jik CHIN

发明人： Choong Eui SONG ,  Sang Ho OH ,  Ho Sik RHO ,  Ji Woong LEE ,  Je Wun LEE ,  Sung Hoon YOUK ,  Jik CHIN

IPC分类号： C07D453/04

CPC分类号： C07D453/04

摘要： The present invention relates to cinchona-based bifunctional organocatalysts and methods for preparing chiral hemiesters using the same. More specifically, the present invention relates to methods for preparing chiral hemiesters from prochiral or meso cyclic acid anhydrides via desymmetrization, using bifunctional cinchona alkaloid catalysts comprising sulfonamide functional groups.

摘要翻译： 本发明涉及基于cinchona的双功能有机催化剂以及使用其制备手性半成品的方法。 更具体地，本发明涉及使用包含磺酰胺官能团的双官能螯合生物碱催化剂通过去对称制备由前手性或内消旋环酸酐制备手性半酯的方法。

公开(公告)号：US5994556A

公开(公告)日：1999-11-30

申请号：US208163

申请日：1998-12-09

申请人： Sang-Gi Lee ,  Choong-Eui Song ,  Chung-Woo Lim

发明人： Sang-Gi Lee ,  Choong-Eui Song ,  Chung-Woo Lim

IPC分类号： C07D263/10 ,  C07C29/143 ,  C07C227/30 ,  C07F9/653 ,  C07D263/08 ,  C07D413/04

CPC分类号： C07F9/653 ,  C07C29/143 ,  C07B2200/07

摘要： The present invention relates to optically pure bis(o-diarylphosphinophenyl)-tetrahydro-bi(1,3-oxazole) compounds represented by the formula (I) and a preparation method thereof. Bis(o-diarylphosphinophenyl)-tetrahydro-bi(1,3-oxazole) compounds of the present invention include (4S,4'S)-2,2'-bis(o-diarylphosphinophenyl)-4,4',5,5'-tetrahydro-4,4'-bi(1,3-oxazole) represented by the formula (Ia) and its enantiomer, (4R,4'R)-2,2'-bis(o-diarylphosphinophenyl)-4,4',5,5'-tetrahydro-4,4'-bi(1,3-oxazole) represented by the formula. The compounds of the present invention can be utilized in asymmetric hydrosilylation, hydrogenation, cyclopropylation and alkylation reactions.

摘要翻译： 本发明涉及由式（I）表示的光学纯双（邻 - 二芳基膦基苯基） - 四氢 - 双（1,3-恶唑）化合物及其制备方法。 本发明的双（邻二芳基膦基苯基） - 四氢 - 双（1,3-恶唑）化合物包括（4S，4'S）-2,2'-双（邻 - 二芳基膦基苯基）-4,4'，5,5' （Ia）表示的四氢-4,4'-双（1,3-恶唑）及其对映异构体，（4R，4'R）-2,2'-双（邻 - 二芳基膦基苯基）-4,4 '，5,5'-四氢-4,4'-双（1,3-恶唑）。 本发明的化合物可用于不对称氢化硅烷化，氢化，环丙基化和烷基化反应。

公开(公告)号：US4999443A

公开(公告)日：1991-03-12

申请号：US360863

申请日：1989-06-02

申请人： Werner Bertleff ,  Dieter Koeffer ,  Wolfgang Klaeui ,  Choong-Eui Song

发明人： Werner Bertleff ,  Dieter Koeffer ,  Wolfgang Klaeui ,  Choong-Eui Song

IPC分类号： B01J31/22 ,  B01J31/16 ,  B01J31/18 ,  C07B61/00 ,  C07C1/00 ,  C07C2/48 ,  C07C5/03 ,  C07C5/08 ,  C07C13/18 ,  C07C45/00 ,  C07C45/50 ,  C07C47/02 ,  C07C67/00 ,  C07C67/347 ,  C07C69/76 ,  C07F15/00 ,  C07F15/06

CPC分类号： C07F15/06 ,  B01J31/1845 ,  B01J31/185 ,  B01J31/2295 ,  C07C2/48 ,  C07C45/50 ,  C07C5/03 ,  C07C5/08 ,  C07F15/0006 ,  C07F15/0046 ,  C07F15/0073 ,  B01J2231/321 ,  B01J2231/328 ,  B01J2231/645 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/827 ,  B01J2531/845 ,  C07C2531/22

摘要： Transition metal complexes of the general formula I[A].sup.x- [Q].sup.+.sub.x Iwhere Q is one equivalent of a cation, x is from 0 to 2 and A is a transition metal complex of the general formula ##STR1## where n is from 1 to 3, M is positively charged cobalt, rhodium, iridium or ruthenium, the ligands B are phosphonic, arsonic, phosphinic and/or arsinic acid ligands which are esterified with identical or different alcohols, one or more of these alcohol components carrying a functional group, L is ##STR2## the radicals R.sup.5 are identical or different radicals from the group consisting of C.sub.1 -C.sub.4 -alkyl and phenyl, p is an integer from 0 to 6, q is an integer from 0 to 5, and R.sup.1 is fluorine, chlorine, bromine, iodine, cyanide, isocyanide, cyanate, isocyanate, thiocyanate, isothiocyanate, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -trialkyl phosphite or triaryl phosphite, are used as catalysts, or prepared in situ, in processes for the cyclotrimerization of acetylene compounds, for the catalytic hydrogenation of unsaturated compounds and for the hydroformylation of alkenes.

摘要翻译： 通式I [A] x- [Q] + xI的过渡金属配合物，其中Q是1当量阳离子，x为0-2，A为通式为A的过渡金属络合物，其中n M为正电荷的钴，铑，铱或钌，配位体B为与相同或不同的醇酯化的膦酸，芳香族，次膦酸和/或亚磺酸配体，一种或多种这些醇组分携带 官能团，L是基团R 5是与C 1 -C 4烷基和苯基相同或不同的基团，p是0至6的整数，q是0至5的整数，并且R 1 使用氟，氯，溴，碘，氰化物，异氰酸酯，氰酸酯，异氰酸酯，硫氰酸酯，异硫氰酸酯，C1-C4烷基，C1-C4-三烷基亚磷酸酯或亚磷酸三芳基酯作为催化剂，或原位制备 乙炔化合物的环三聚化，用于不饱和化合物的催化氢化 并且用于烯烃的加氢甲酰化。

公开(公告)号：US08580964B2

公开(公告)日：2013-11-12

申请号：US13008793

申请日：2011-01-18

申请人： Choong Eui Song ,  Sang Ho Oh ,  Ho Sik Rho ,  Ji Woong Lee ,  Je Wun Lee ,  Sung Hoon Youk ,  Jik Chin

发明人： Choong Eui Song ,  Sang Ho Oh ,  Ho Sik Rho ,  Ji Woong Lee ,  Je Wun Lee ,  Sung Hoon Youk ,  Jik Chin

IPC分类号： C07D453/04

CPC分类号： C07D453/04

摘要： The present invention relates to cinchona-based bifunctional organocatalysts and methods for preparing chiral hemiesters using the same. More specifically, the present invention relates to methods for preparing chiral hemiesters from prochiral or meso cyclic acid anhydrides via desymmetrization, using bifunctional cinchona alkaloid catalysts comprising sulfonamide functional groups.

摘要翻译： 本发明涉及基于cinchona的双功能有机催化剂以及使用其制备手性半成品的方法。 更具体地，本发明涉及使用包含磺酰胺官能团的双官能螯合生物碱催化剂通过去对称制备由前手性或内消旋环酸酐制备手性半酯的方法。

公开(公告)号：US5968867A

公开(公告)日：1999-10-19

申请号：US48275

申请日：1998-03-26

申请人： Choong Eui Song ,  Jung Woon Yang

发明人： Choong Eui Song ,  Jung Woon Yang

IPC分类号： B01J31/02 ,  B01J31/40 ,  C07C29/03 ,  C07D453/02 ,  B01J31/00 ,  B01J21/08 ,  B01J21/12 ,  B01J21/14

CPC分类号： C07D453/02 ,  B01J31/0254 ,  C07C29/03 ,  B01J2231/32 ,  C07B2200/07 ,  C07C2101/14

摘要： The present invention relates to silica gel supported bis-cinchona alkaloid compounds of the formula: ##STR1## wherein Q is dihydroquininyl or dihydroquinindinyl; X is a compound having 4 carbon atoms; and R is methoxy, ethoxy or methyl; and methods of preparation and use thereof. The silica gel supported bis-cinchona alkaloid derivatives of this invention are useful re-useable catalysts for preparing vicinal diols by asymmetric dihydroxylation of olefins.

摘要翻译： 本发明涉及下式的硅胶负载的双 - 焦虑激素生物碱化合物：其中Q是二氢喹啉或二氢喹啉基; X是具有4个碳原子的化合物; R为甲氧基，乙氧基或甲基; 及其制备和使用方法。 本发明的硅胶负载双螯合生物碱衍生物是通过烯烃的不对称二羟基化制备连环二醇的有用的可再用催化剂。