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    SYSTEM AND METHOD FOR FOUR DIMENSIONAL ANGIOGRAPHY AND FLUOROSCOPY
    2.
    发明申请
    SYSTEM AND METHOD FOR FOUR DIMENSIONAL ANGIOGRAPHY AND FLUOROSCOPY 有权
    用于四维血管造影和荧光的系统和方法

    公开(公告)号：US20110038517A1

    公开(公告)日：2011-02-17

    申请号：US12692340

    申请日：2010-01-22

    Applicant: Charles A. Mistretta ,  Charles M. Strother

    Inventor： Charles A. Mistretta ,  Charles M. Strother

    IPC: G06K9/62

    CPC classification number: A61B6/485 ,  A61B6/02 ,  A61B6/12 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/486 ,  A61B6/487 ,  A61B6/504 ,  A61B6/5223 ,  A61B6/5247 ,  A61M5/007 ,  G06T11/008 ,  G06T2211/404 ,  G06T2211/412 ,  G06T2211/436 ,  Y10S378/901

    Abstract: A method for generating time-resolved 3D medical images of a subject by imparting temporal information from a time-series of 2D medical images into 3D images of the subject. Generally speaking, this is achieved by acquiring image data using a medical imaging system, generating a time-series of 2D images of a ROI from at least a portion of the acquired image data, reconstructing a 3D image substantially without temporal resolution from the acquired image data, and selectively combining the time series of 2D images with the 3D image. Selective combination typically involves registering frames of the time-series of 2D images with the 3D image, projecting pixel values from the 2D image frames “into” the 3D image, and weighting the 3D image with the projected pixel values for each frame of the time-series of 2D images. This method is particularly useful for generating 4D-DSA images (that is, time-resolved 3D-DSA images) from a time-series of 2D-DSA images acquired via single plane or biplane x-ray acquisitions with 3D images acquired via a rotational DSA acquisition. 4D-DSA images can be generated either by using multiple injections or by using a single injection by combining a time-series of 2D-DSA images generated from individual projections from a rotational x-ray acquisition with a 3D image reconstructed from substantially all of the projection views acquired during the rotational x-ray acquisition. These DSA images may have a spatial resolution on the order of 5123 pixels and a temporal resolution of about 30 frames per second, which represents an increase over traditional 3D-DSA frame rates by a factor of between 150 and 600.

    Abstract translation: 一种用于通过将来自2D医学图像的时间序列的时间信息传递到对象的3D图像来生成对象的时间分辨3D医学图像的方法。 一般来说，这是通过使用医学成像系统获取图像数据来实现的，从所获取的图像数据的至少一部分生成ROI的2D图像的时间序列，从获取的图像重建基本上没有时间分辨率的3D图像 数据，并且选择性地将2D图像的时间系列与3D图像组合。 选择性组合通常涉及将2D图像的时间序列的帧注册到3D图像，将来自2D图像帧的像素值投影到“3D”图像中，并且对于每个时间帧的投影像素值对3D图像进行加权 系列的二维图像。 该方法对于通过经由单平面或双平面x射线采集获得的2D-DSA图像的时间序列与经由旋转获取的3D图像生成4D-DSA图像（即时间分辨3D-DSA图像）特别有用 DSA收购 可以通过使用多次注射或通过将从旋转X射线获取的各个投影产生的时间序列的2D-DSA图像与从基本上全部重建的3D图像组合而使用多次注射来生成4D-DSA图像 在旋转X射线采集期间获得的投影视图。 这些DSA图像可以具有大约5123像素的空间分辨率和大约每秒30帧的时间分辨率，这表示比传统的3D-DSA帧速率提高了150到600之间的因子。

    Apparatus and method for treating an aneurysm
    4.
    发明授权
    Apparatus and method for treating an aneurysm 有权
    用于治疗动脉瘤的装置和方法

    公开(公告)号：US09211202B2

    公开(公告)日：2015-12-15

    申请号：US12258264

    申请日：2008-10-24

    Applicant: Charles M. Strother ,  Jingfeng Jiang

    Inventor： Charles M. Strother ,  Jingfeng Jiang

    IPC: A61F2/06 ,  A61F2/82

    CPC classification number: A61F2/82 ,  A61F2002/068 ,  A61F2002/823

    Abstract: In an apparatus and method for treating an aneurysm, a flow control member is positioned within a blood vessel at least in part upstream of an aneurysm and extending radially inward of the blood vessel wall into the flow path of blood flowing within the blood vessel. The flow control member alters the blood flow path within the blood vessel upstream of the aneurysm to inhibit blood flow to the aneurysm. A retention member may be positioned within the blood vessel at least in part upstream from the aneurysm and having an outer surface engageable with the blood vessel wall. In such an instance, the flow control member is retained by the retention member and extends radially inward of the blood vessel wall upstream from the aneurysm.

    Abstract translation: 在用于治疗动脉瘤的装置和方法中，流动控制构件位于动脉瘤的至少部分上游的血管内，并且将血管壁的径向向内延伸到血管内流动的血液的流动路径中。 流量控制部件改变动脉瘤上游血管内的血流路径，抑制血液流向动脉瘤。 保留构件可以至少部分地位于动脉瘤上游并且具有可与血管壁接合的外表面中的血管内。 在这种情况下，流动控制构件被保持构件保持，并且在动脉瘤上游的血管壁的径向向内延伸。

    Detachable balloon catheter
    6.
    发明授权
    Detachable balloon catheter 失效
    可拆卸球囊导管

    公开(公告)号：US4364392A

    公开(公告)日：1982-12-21

    申请号：US212759

    申请日：1980-12-04

    Applicant: Charles M. Strother ,  Balakrishna V. Kudva

    Inventor： Charles M. Strother ,  Balakrishna V. Kudva

    IPC: A61B17/00 ,  A61B17/12 ,  A61F2/00 ,  A61M25/00

    CPC classification number: A61B17/0057 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12195 ,  A61B2017/00557 ,  A61F2250/0067 ,  A61M2025/1052 ,  A61M2025/1054 ,  A61M2025/1072

    Abstract: A method and apparatus is disclosed for providing therapeutic occlusions of blood vessels and other body tubular structures using an inflatable balloon (11) mounted at the end of a catheter (15). The balloon (11) and catheter (15) are passed through a blood vessel (12) until the balloon (15) reaches the desired location of the occlusion; a suspension of solid filler particles (27) in a carrier liquid is then pumped through the catheter tube (15) and inflates the blloon (11) until it blocks off the blood vessel. The carrier liquid is forced out through the porous walls of the balloon, leaving a compacted mass of filler particles which will not allow the balloon to shrink. Ridges (20) on the end of the catheter tube (15) engage mating grooves (21) in the neck portion (14) of the balloon structure during insertion and filling of the balloon; the size, shape, and number of these ridges and grooves can be selected to provide a desired force required to detach the catheter tube from the balloon. A valve (18) in the neck portion (14) of the balloon structure allows the particle suspension to pass into the balloon but blocks flow of particles out of the balloon while preferably allowing the carrier liquid to pass therethrough. Medication may be impregnated in either the particles in the balloon or the porous balloon walls to allow controlled release of the medication into the bloodstream.

    Abstract translation: 公开了一种使用安装在导管（15）的端部处的可充气气囊（11）来提供血管和其他身体管状结构的治疗性闭塞的方法和装置。 气球（11）和导管（15）穿过血管（12）直到球囊（15）到达闭塞的期望位置; 然后将固体填料颗粒（27）在载体液体中的悬浮液泵送通过导管（15）并使气泡（11）膨胀，直到其堵塞血管。 载体液体被挤出通过球囊的多孔壁，留下一个压实的填料颗粒物质，这将不允许球囊收缩。 在插入和填充球囊期间，导管管（15）端部上的脊（20）与球囊结构的颈部（14）中的配合凹槽（21）接合; 可以选择这些脊和槽的尺寸，形状和数量以提供将导管从气囊分离所需的力。 球囊结构的颈部（14）中的阀（18）允许颗粒悬浮液进入球囊，但阻止颗粒流出球囊，同时优选允许载液通过。 药物可以浸渍在球囊或多孔气囊壁中的颗粒中，以允许将药物控制释放到血流中。

    System and method for filtration reduced equalized exposure computed tomography
    8.
    发明授权
    System and method for filtration reduced equalized exposure computed tomography 有权
    用于过滤的系统和方法减少了平衡曝光计算机断层扫描

    公开(公告)号：US08755584B2

    公开(公告)日：2014-06-17

    申请号：US13011789

    申请日：2011-01-21

    Applicant: Charles A. Mistretta ,  Charles M. Strother

    Inventor： Charles A. Mistretta ,  Charles M. Strother

    IPC: G06K9/00 ,  A61B6/00 ,  A61B6/03 ,  G21K1/10

    CPC classification number: A61B6/4035 ,  A61B6/032 ,  A61B6/507 ,  G21K1/10 ,  G21K2207/00

    Abstract: A method is disclosed for producing a computed tomographic image of a subject, the method including: using a radiation source and detector, obtaining radiation transmission information relating to a region of interest in the subject; using the source and detector; obtaining a series of projection images of the region of interest. Each projection image is obtained by: directing an imaging beam of radiation from the source through the region of interest onto the detector along a respective direction; the detector having a detection area.

    Abstract translation: 公开了一种用于产生对象的计算机断层图像的方法，所述方法包括：使用辐射源和检测器，获得与所述对象中的感兴趣区域相关的辐射传输信息; 使用源和检测器; 获得感兴趣区域的一系列投影图像。 每个投影图像通过以下方式获得：将来自源的成像射束束通过感兴趣区域沿相应方向引导到检测器上; 检测器具有检测区域。

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