Image acquisition and reconstruction method for functional magnetic resonance imaging
    3.
    发明授权
    Image acquisition and reconstruction method for functional magnetic resonance imaging 有权
    功能磁共振成像的图像采集和重建方法

    公开(公告)号:US07917190B2

    公开(公告)日:2011-03-29

    申请号:US11524571

    申请日:2006-09-21

    Abstract: Acquisition of MR data during a fMRI study employs a hybrid PR pulse sequence to acquire projection views from which multi-slice image frames may be reconstructed that depict the BOLD response to an applied stimulus or performed task. Composite images are reconstructed at each slice using the combined interleaved projection views from all the acquired image frames. The composite images are used to reconstruct the highly undersampled image frames.

    Abstract translation: 在fMRI研究期间获取MR数据采用混合PR脉冲序列来获取投影视图,可从中重建多切片图像帧,其描绘对应用的刺激或执行任务的BOLD响应。 使用来自所有获取的图像帧的组合的交错投影视图在每个切片处重建复合图像。 合成图像用于重构高度欠采样的图像帧。

    SYSTEM AND METHOD FOR FOUR DIMENSIONAL ANGIOGRAPHY AND FLUOROSCOPY
    4.
    发明申请
    SYSTEM AND METHOD FOR FOUR DIMENSIONAL ANGIOGRAPHY AND FLUOROSCOPY 有权
    用于四维血管造影和荧光的系统和方法

    公开(公告)号:US20110038517A1

    公开(公告)日:2011-02-17

    申请号:US12692340

    申请日:2010-01-22

    Abstract: A method for generating time-resolved 3D medical images of a subject by imparting temporal information from a time-series of 2D medical images into 3D images of the subject. Generally speaking, this is achieved by acquiring image data using a medical imaging system, generating a time-series of 2D images of a ROI from at least a portion of the acquired image data, reconstructing a 3D image substantially without temporal resolution from the acquired image data, and selectively combining the time series of 2D images with the 3D image. Selective combination typically involves registering frames of the time-series of 2D images with the 3D image, projecting pixel values from the 2D image frames “into” the 3D image, and weighting the 3D image with the projected pixel values for each frame of the time-series of 2D images. This method is particularly useful for generating 4D-DSA images (that is, time-resolved 3D-DSA images) from a time-series of 2D-DSA images acquired via single plane or biplane x-ray acquisitions with 3D images acquired via a rotational DSA acquisition. 4D-DSA images can be generated either by using multiple injections or by using a single injection by combining a time-series of 2D-DSA images generated from individual projections from a rotational x-ray acquisition with a 3D image reconstructed from substantially all of the projection views acquired during the rotational x-ray acquisition. These DSA images may have a spatial resolution on the order of 5123 pixels and a temporal resolution of about 30 frames per second, which represents an increase over traditional 3D-DSA frame rates by a factor of between 150 and 600.

    Abstract translation: 一种用于通过将来自2D医学图像的时间序列的时间信息传递到对象的3D图像来生成对象的时间分辨3D医学图像的方法。 一般来说,这是通过使用医学成像系统获取图像数据来实现的,从所获取的图像数据的至少一部分生成ROI的2D图像的时间序列,从获取的图像重建基本上没有时间分辨率的3D图像 数据,并且选择性地将2D图像的时间系列与3D图像组合。 选择性组合通常涉及将2D图像的时间序列的帧注册到3D图像,将来自2D图像帧的像素值投影到“3D”图像中,并且对于每个时间帧的投影像素值对3D图像进行加权 系列的二维图像。 该方法对于通过经由单平面或双平面x射线采集获得的2D-DSA图像的时间序列与经由旋转获取的3D图像生成4D-DSA图像(即时间分辨3D-DSA图像)特别有用 DSA收购 可以通过使用多次注射或通过将从旋转X射线获取的各个投影产生的时间序列的2D-DSA图像与从基本上全部重建的3D图像组合而使用多次注射来生成4D-DSA图像 在旋转X射线采集期间获得的投影视图。 这些DSA图像可以具有大约5123像素的空间分辨率和大约每秒30帧的时间分辨率,这表示比传统的3D-DSA帧速率提高了150到600之间的因子。

    Magnetic resonance angiography with automated vessel segmentation
    5.
    发明授权
    Magnetic resonance angiography with automated vessel segmentation 有权
    磁共振血管造影与自动血管分割

    公开(公告)号:US07583992B2

    公开(公告)日:2009-09-01

    申请号:US10485433

    申请日:2001-03-16

    CPC classification number: G01R33/563 G01R33/281

    Abstract: A magnetic resonance angiogram (MRA) is acquired using a contrast enhancement method in which a series of NMR images are rapidly acquired during a time resolved phase of the examination in which the contrast bolus makes a first pass through the arteries and veins. Arterial and venous voxels are automatically identified in the images using either of two disclosed methods. The signals from identified arterial voxels are used to produce an arterial contrast enhancement reference curve that is used to segment arterial voxels by a correlation process. Venous voxels are segmented in the same manner using a calculated venous contrast enhancement reference curve.

    Abstract translation: 使用对比度增强方法获得磁共振血管造影(MRA),其中在检查的时间分辨阶段期间快速获取一系列NMR图像,其中对比剂推注首先通过动脉和静脉。 使用两种公开的方法之一,在图像中自动识别动脉和静脉体素。 来自确定的动脉体素的信号用于产生用于通过相关过程分割动脉体素的动脉造影增强参考曲线。 使用计算的静脉造影增强参考曲线以相同的方式分割静脉体素。

    Backprojection reconstruction method for CT imaging
    6.
    发明授权
    Backprojection reconstruction method for CT imaging 有权
    CT成像反投影重建方法

    公开(公告)号:US07545901B2

    公开(公告)日:2009-06-09

    申请号:US11482858

    申请日:2006-07-07

    Abstract: Two-dimensional or three-dimensional, time-resolved CT frame images are acquired during a dynamic study of a subject. A composite image is produced and this is used to reconstruct each CT frame image by weighting the backprojection of each projection view acquired for that image frame by the corresponding value in the composite image. This weighted backprojection enables artifact-free image frames to be produced with far fewer projection views of the subject. The composite image may be reconstructed from views acquired separately, or it may be produced by combining views acquired during the course of the dynamic study.

    Abstract translation: 在对受试者的动态研究期间获取二维或三维,时间分辨的CT帧图像。 生成合成图像,并且通过将对于该图像帧获取的每个投影视图的反投影加权到合成图像中的相应值,来用于重构每个CT帧图像。 这种加权反投影使得无人影像的图像帧能够以较少的主体投影视图生成。 复合图像可以从单独获取的视图重构,或者可以通过组合在动态研究过程中获取的视图来产生。

    Phase contrast imaging using interleaved projection data
    7.
    发明授权
    Phase contrast imaging using interleaved projection data 有权
    相位成像使用交错投影数据

    公开(公告)号:US06188922B1

    公开(公告)日:2001-02-13

    申请号:US09314226

    申请日:1999-05-18

    CPC classification number: G01R33/56308 G01R33/4833 G01R33/56316

    Abstract: A magnetic resonance angiogram (MRA) is acquired using a pulse sequence that samples k-space at a projection angle. The acquired NMR signal is sensitized to spin motion with a bipolar motion encoding gradient and the pulse sequence is repeated to sample k-space at a set of different projection angles. A phase image is reconstructed from the acquired NMR signals using a filtered backprojection technique. Additional sets of projections with different motion encoding directions are acquired at interleaved projection angles, and the reconstructed phase images are combined to provide a velocity image.

    Abstract translation: 使用以投影角度对k空间进行采样的脉冲序列来获取磁共振血管造影(MRA)。 获得的NMR信号用双极运动编码梯度对自旋运动敏感,重复脉冲序列以一组不同的投影角度对k空间进行采样。 使用滤波反投影技术从获取的NMR信号重建相位图像。 以交错的投影角度获取具有不同运动编码方向的附加的投影集合,并且重构的相位图像被组合以提供速度图像。

    Adaptive NMR angiographic reprojection method
    9.
    发明授权
    Adaptive NMR angiographic reprojection method 失效
    自适应核磁共振血管造影重建方法

    公开(公告)号:US5204627A

    公开(公告)日:1993-04-20

    申请号:US669143

    申请日:1991-03-14

    CPC classification number: G01R33/563 G01R33/56

    Abstract: A magnetic resonance angiogram is produced by projecting a 3D array of motion sensitized NMR data. A mask which locates the vessels in the 3D array is produced by thresholding the NMR data, and this mask is combined with the 3D NMR data set to exclude signals produced by surrounding stationary tissues. An integration projection technique is used to produce the angiogram from the masked data set.

    Abstract translation: 通过投影运动敏化NMR数据的3D阵列产生磁共振血管造影。 通过对NMR数据进行阈值产生定位3D阵列中的血管的掩模,并将该掩模与3D NMR数据组合以排除由周围的静止组织产生的信号。 使用积分投影技术从掩蔽的数据集中产生血管造影。

    Phase contrast, line-scanned method for NMR angiography
    10.
    发明授权
    Phase contrast, line-scanned method for NMR angiography 失效
    相位对比度,NMR扫描方法

    公开(公告)号:US5031624A

    公开(公告)日:1991-07-16

    申请号:US568938

    申请日:1990-08-17

    CPC classification number: G01R33/56316 G01R33/5673

    Abstract: An NMR angiogram is produced using a line scan data acquisition. Each line of NMR data is acquired twice, once with a velocity sensitizing gradient having a positive first moment and once with a velocity sensitizing gradient having a negative first moment. The two signals from the acquisition are subtracted to cancel signals from stationary spins while enhancing signals from flowing spins. The magnitude of the velocity sensitizing gradient moment is changed during the cardiac cycle so that aliasing does not occur at high blood velocities and the signal strength does not drop too low at low blood velocities. An angiogram is produced by reconstructing an image from line scan data acquired from a series of slices.

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