公开(公告)号：US08636001B2

公开(公告)日：2014-01-28

申请号：US12484129

申请日：2009-06-12

申请人： Chad C. Smutney ,  P. Spencer Kinsey ,  Carl R. Sahi ,  Benoit Adamo ,  John M. Polidoro ,  Scott McLean ,  Dennis Overfileld ,  Anthony Bryant ,  Tom He ,  Alfred Mann

发明人： Chad C. Smutney ,  P. Spencer Kinsey ,  Carl R. Sahi ,  Benoit Adamo ,  John M. Polidoro ,  Scott McLean ,  Dennis Overfileld ,  Anthony Bryant ,  Tom He ,  Alfred Mann

IPC分类号： A61M15/00

CPC分类号： A61M15/0045 ,  A61K9/0075 ,  A61K38/00 ,  A61K38/1709 ,  A61K38/22 ,  A61K38/26 ,  A61K38/28 ,  A61K47/22 ,  A61M15/0021 ,  A61M15/0023 ,  A61M15/0028 ,  A61M15/0043 ,  A61M15/0048 ,  A61M15/0086 ,  A61M15/0091 ,  A61M2202/064 ,  A61M2205/6081 ,  A61M2206/20

摘要： A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.

公开(公告)号：US20120122775A1

公开(公告)日：2012-05-17

申请号：US13357821

申请日：2012-01-25

申请人： Anders Hasager Boss ,  Richard Petrucci ,  Campbell Howard ,  Alfred Mann

发明人： Anders Hasager Boss ,  Richard Petrucci ,  Campbell Howard ,  Alfred Mann

IPC分类号： A61K38/28 ,  A61P3/10

CPC分类号： A61K38/28 ,  A61K9/0021 ,  A61K9/0075 ,  A61K47/545

摘要： Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.

公开(公告)号：US20080033357A1

公开(公告)日：2008-02-07

申请号：US11841382

申请日：2007-08-20

申请人： Alfred Mann ,  James Causey ,  Alan Haubach ,  Luis Malave ,  John Livingston ,  Cliff Hague ,  Chad Srisathapat ,  Jay Yonemoto ,  Deborah Ruppert ,  Dennis Bishop ,  Adrian Gut ,  Bob Murtfeldt

发明人： Alfred Mann ,  James Causey ,  Alan Haubach ,  Luis Malave ,  John Livingston ,  Cliff Hague ,  Chad Srisathapat ,  Jay Yonemoto ,  Deborah Ruppert ,  Dennis Bishop ,  Adrian Gut ,  Bob Murtfeldt

IPC分类号： A61M37/00

CPC分类号： A61M5/1723 ,  A61M5/14244 ,  A61M5/172 ,  A61M5/36 ,  A61M2005/1402 ,  A61M2005/1403 ,  A61M2205/18 ,  A61M2205/3561 ,  A61M2205/3592 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2209/01 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  Y02A90/22 ,  Y02A90/26 ,  Y10S128/903

摘要： An infusion system for infusing a liquid into a body includes an external infusion device and a remote commander. The external infusion device includes a housing, a receiver, a processor and an indication device. The receiver is coupled to the housing and for receiving remotely generated commands. The processor is coupled to the housing and the receiver to receive remotely generated commands and to control the external infusion device in accordance with the commands. The indication device indicates when a command has been received and indicates when the command is being utilized to control the external infusion device so that the external infusion device is capable of being concealed from view when being remotely commanded. The remote commander includes a commander housing, a keypad for transmitting commands, and a transmitter for transmitting commands to the receiver of the external infusion device.

摘要翻译： 用于将液体注入身体的输注系统包括外部输注装置和远程指挥器。 外部输注装置包括壳体，接收器，处理器和指示装置。 接收器耦合到壳体并用于接收远程产生的命令。 处理器耦合到壳体和接收器以接收远程产生的命令并根据命令控制外部输注装置。 指示装置指示何时已经接收到命令，并且指示何时正在利用命令来控制外部输注装置，使得外部输注装置能够在远程命令时被隐藏。 遥控器包括指挥器壳体，用于发送命令的键盘和用于向外部输注装置的接收器发送命令的发射器。

公开(公告)号：US20080030369A1

公开(公告)日：2008-02-07

申请号：US11906516

申请日：2007-10-02

申请人： Alfred Mann ,  Richard Purvis ,  John Mastrototaro ,  James Causey ,  James Henke ,  Peter Hong ,  John Livingston ,  Clifford Hague ,  Brad Hite

发明人： Alfred Mann ,  Richard Purvis ,  John Mastrototaro ,  James Causey ,  James Henke ,  Peter Hong ,  John Livingston ,  Clifford Hague ,  Brad Hite

IPC分类号： A61B1/00

CPC分类号： A61B5/1495 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/6848 ,  A61B5/6849 ,  A61B2560/0214 ,  A61B2560/0223 ,  A61M2005/1726

摘要： A telemetered characteristic monitor system includes a remotely located data receiving device, a sensor for producing signal indicative of a characteristic of a user, and a transmitter device. The transmitter device includes a housing, a sensor connector, a processor, and a transmitter. The transmitter receives the signals from the sensor and wirelessly transmits the processed signals to the remotely located data receiving device. The processor coupled to the sensor processes the signals from the sensor for transmission to the remotely located data receiving device. The data receiving device may be a characteristic monitor, a data receiver that provides data to another device, an RF programmer for a medical device, a medication delivery device (such as an infusion pump), or the like.

公开(公告)号：US20070063105A1

公开(公告)日：2007-03-22

申请号：US11055287

申请日：2005-02-09

申请人： Alfred Mann

发明人： Alfred Mann

IPC分类号： B64G1/52

CPC分类号： B64G1/50

摘要： Disclosed is a method and apparatus for maintaining the temperature of thermally sensitive components in a satellite within a preferred operating range. The apparatus employs a heat absorber disposed between the outer hull of the satellite and the components. The heat absorber includes heat-absorbing material preferably exhibiting a phase change at a temperature within a preferred operating range of the components.

摘要翻译： 公开了一种用于将卫星中的热敏组件的温度保持在优选操作范围内的方法和装置。 该装置采用设置在卫星的外壳和部件之间的散热器。 吸热器包括吸热材料，优选在组件的优选工作范围内的温度下呈现相变。

公开(公告)号：US20060007017A1

公开(公告)日：2006-01-12

申请号：US11225790

申请日：2005-09-12

申请人： Alfred Mann ,  Richard Purvis ,  John Mastrototaro ,  James Causey ,  James Henke ,  Peter Hong ,  John Livingston ,  Clifford Hague ,  Brad Hite

发明人： Alfred Mann ,  Richard Purvis ,  John Mastrototaro ,  James Causey ,  James Henke ,  Peter Hong ,  John Livingston ,  Clifford Hague ,  Brad Hite

IPC分类号： G08C19/22

CPC分类号： A61B5/1495 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/6848 ,  A61B5/6849 ,  A61B2560/0214 ,  A61B2560/0223 ,  A61M2005/1726 ,  G06F19/00

摘要： A telemetered characteristic monitor system includes a remotely located data receiving device, a sensor for producing signal indicative of a characteristic of a user, and a transmitter device. The transmitter device includes a housing, a sensor connector, a processor, and a transmitter. The transmitter receives the signals from the sensor and Tirelessly transmits the processed signals to the remotely located data receiving device. The processor coupled to the sensor processes the signals from the sensor for transmission to the remotely located data receiving device. The data receiving device may be a characteristic monitor, a data receiver that provides data to another device, an RF programmer for a medical device, a medication delivery device (such as an infusion pump), or the like.

公开(公告)号：US20060001550A1

公开(公告)日：2006-01-05

申请号：US11225296

申请日：2005-09-12

申请人： Alfred Mann ,  Richard Purvis ,  John Mastrototaro ,  James Causey ,  James Henke ,  Peter Hong ,  John Livingston ,  Clifford Hague ,  Brad Hite

发明人： Alfred Mann ,  Richard Purvis ,  John Mastrototaro ,  James Causey ,  James Henke ,  Peter Hong ,  John Livingston ,  Clifford Hague ,  Brad Hite

IPC分类号： G08C19/22

CPC分类号： A61B5/1495 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/6848 ,  A61B5/6849 ,  A61B2560/0214 ,  A61B2560/0223 ,  A61M2005/1726 ,  G06F19/00

摘要： A telemetered characteristic monitor system includes a remotely located data receiving device, a sensor for producing signal indicative of a characteristic of a user, and a transmitter device. The transmitter device includes a housing, a sensor connector, a processor, and a transmitter. The transmitter receives the signals from the sensor and Tirelessly transmits the processed signals to the remotely located data receiving device. The processor coupled to the sensor processes the signals from the sensor for transmission to the remotely located data receiving device. The data receiving device may be a characteristic monitor, a data receiver that provides data to another device, an RF programmer for a medical device, a medication delivery device (such as an infusion pump), or the like.

公开(公告)号：US20050031145A1

公开(公告)日：2005-02-10

申请号：US10932813

申请日：2004-09-01

申请人： Albert Maltan ,  Alfred Mann ,  James McGivern ,  Philip Lee

发明人： Albert Maltan ,  Alfred Mann ,  James McGivern ,  Philip Lee

IPC分类号： H04R25/00 ,  H04R25/02

CPC分类号： H04R25/505 ,  H04R25/554 ,  H04R25/558 ,  H04R25/60 ,  H04R25/65 ,  H04R25/658 ,  H04R2225/51 ,  H04R2225/67 ,  H04R2420/07

摘要： A hearing aid module is shaped for insertion into a tunnel made through the soft tissue that connects the retro-auricular space with the ear canal. The hearing aid module contains a speaker or auditory transducer, a battery or other power source powering the module, signal processing circuitry, and a microphone. Telemetry circuitry within the module allows the signal processing circuitry to be programmed with a desired frequency response or signal processing strategy using an external programming unit. A remote control unit permits the user to make simple adjustments, such as volume and/or tone (frequency) control.

摘要翻译： 助听器模块被成形为插入到通过将耳环空间与耳道连接的软组织制成的隧道中。 助听器模块包括扬声器或听觉换能器，为模块供电的电池或其他电源，信号处理电路和麦克风。 模块内的遥测电路允许使用外部编程单元对信号处理电路进行所需的频率响应或信号处理策略的编程。 遥控单元允许用户进行简单的调节，例如音量和/或音调（频率）控制。

公开(公告)号：US08258095B2

公开(公告)日：2012-09-04

申请号：US12539499

申请日：2009-08-11

申请人： Anders Hasager Boss ,  Richard Petrucci ,  Campbell Howard ,  Alfred Mann

发明人： Anders Hasager Boss ,  Richard Petrucci ,  Campbell Howard ,  Alfred Mann

IPC分类号： A61P3/10 ,  A61K38/00

CPC分类号： A61K38/28 ,  A61K9/0021 ,  A61K9/0075 ,  A61K47/545

摘要： Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.

摘要翻译： 本文公开了一种通过超快速作用的胰岛素和甘精胰岛素的组合治疗高血糖的改进方法，其包括餐前施用超级胰岛素，以及在醒来6小时内施用第一剂甘精胰岛素。

公开(公告)号：US20100035795A1

公开(公告)日：2010-02-11

申请号：US12539499

申请日：2009-08-11

申请人： Anders Hasager Boss ,  Richard Petrucci ,  Campbell Howard ,  Alfred Mann

发明人： Anders Hasager Boss ,  Richard Petrucci ,  Campbell Howard ,  Alfred Mann

IPC分类号： A61K38/28 ,  A61P3/10

CPC分类号： A61K38/28 ,  A61K9/0021 ,  A61K9/0075 ,  A61K47/545

摘要： Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day.