COMPOSITIONS OF CIS-9, TRANS-11 CONJUGATED LINOLEIC ACID AND VACCENIC ACID AND USES THEREOF
    7.
    发明申请
    COMPOSITIONS OF CIS-9, TRANS-11 CONJUGATED LINOLEIC ACID AND VACCENIC ACID AND USES THEREOF 审中-公开
    CIS-9,TRANS-11结合的亚硝酸和过敏酸的组合物及其用途

    公开(公告)号:US20090048339A1

    公开(公告)日:2009-02-19

    申请号:US12093307

    申请日:2006-11-10

    CPC分类号: A61K31/201 A61K2300/00

    摘要: The invention relates to use of the cis-9, trans-11 isomer of conjugated linoleic acid or a salt or ester thereof (cis-9, trans-11 CLA) and vaccenic acid or a salt or ester thereof (VA) to treat or prevent conditions associated with one or more of leukocyte infiltration, eosinophilia, airway remodelling, bronchoconstriction, mucus hypersecretion, and lung and skin inflammation. The present invention also relates to a composition comprising cis-9, trans-11 CLA and VA and use of the composition to treat or pre-vent conditions associated with one or more of leukocyte infiltration, eosinophilia, airway remodelling, bronchoconstriction, mucus hypersecretion, and lung and skin inflammation. In particular, the medicinal uses, compositions and methods of the invention may be used to treat or prevent conditions such as asthma and dermatitis, and related disorders.

    摘要翻译: 本发明涉及共轭亚油酸或其盐或酯(顺式-9,反式-11 CLA)和异柠檬酸或其盐或酯(VA)的顺式-9反式-11异构体用于治疗或 预防与白细胞浸润,嗜酸粒细胞增多,气道重塑,支气管收缩,粘液分泌过多以及肺和皮肤炎症中的一种或多种相关的病症。 本发明还涉及包含顺式-9,反式-11 CLA和VA的组合物,该组合物用于治疗或预处理与白细胞浸润,嗜酸粒细胞增多,气道重塑,支气管收缩,粘液分泌过多, 和肺和皮肤炎症。 特别地,本发明的药用,组合物和方法可用于治疗或预防诸如哮喘和皮炎的病症以及相关疾病。