公开(公告)号：US5705616A

公开(公告)日：1998-01-06

申请号：US461593

申请日：1995-06-05

Applicant: Ludwig Lehle ,  Klaus Lehnert ,  Erhard Kopetzki

Inventor： Ludwig Lehle ,  Klaus Lehnert ,  Erhard Kopetzki

IPC: C07H21/04 ,  C07K14/395 ,  C12N1/16 ,  C12N1/19 ,  C12N9/04 ,  C12N15/00 ,  C12N15/09 ,  C12P21/00 ,  C12P21/02 ,  C12R1/865 ,  C07K1/00 ,  C12N1/14 ,  C12N1/18

CPC classification number: C12N9/0006 ,  C12N1/16 ,  C12P21/005 ,  C12R1/85

Abstract: Saccharomyces mutants with defects in N-glycosylation which are obtainable by �.sup.3 H!-mannose suicide selection, introduction of one or several selective markers, selection of those strains which, after transformation with the plasmid YEpL/glucose oxidase, secrete 10 mg/l GOD or more into the culture medium after culture under standard conditions, are allelic to the ngd mutations in Saccharomyces cerevisiae, DSM 7042, DSM 7338, DSM 7160 and/or 7340 and express proteins with a uniform carbohydrate structure.

Abstract translation: 具有N-糖基化缺陷的糖酵母突变体，其可以通过[3 H] - 甘露糖自杀选择获得，引入一个或几个选择性标记，选择在用质粒YEpL /葡萄糖氧化酶转化后分泌10mg / l GOD的那些菌株 或更多的培养基在标准条件下培养后，等同于酿酒酵母，DSM 7042，DSM 7338，DSM 7160和/或7340中的ngd突变，并表达具有均匀碳水化合物结构的蛋白质。

公开(公告)号：US4420241A

公开(公告)日：1983-12-13

申请号：US424997

申请日：1982-09-27

Applicant: Alfons Kastl ,  Klaus Lehnert ,  Horst Koninger ,  Gu Schirk

Inventor： Alfons Kastl ,  Klaus Lehnert ,  Horst Koninger ,  Gu Schirk

IPC: F16C27/06 ,  F16C13/00 ,  F16C13/02 ,  F16C27/02 ,  G03D3/08 ,  G03D3/13 ,  G03D13/02 ,  G03D9/02

CPC classification number: F16C13/02 ,  F16C27/02 ,  G03D3/13

Abstract: A film-treatment device has two spaced and generally parallel mounting plates each having a pair of plate holes and respective pairs of journals in the plate holes having respective journal holes centered on a pair of journal axes. The journal holes of the plates are coaxial with each other and the two journal axes are parallel. Rollers centered on respective roller axes each have a pair of substantially cylindrical end trunnions centered on the respective roller axis and rotatably received in a respective one of the journal holes for rotation of the respective roller therein with its roller axis coaxial with the respective journal axis. The journals of one of the journal axes are constructed so the respective roller can move against spring force limitedly away from the other roller. At least one journal of each journal axis is formed at the respective journal hole with two semicylindrical journal surfaces spaced axially apart, centered on the respective journal axis, of the same radius of curvature as the respective trunnion, and diametrally oppositely concave toward each other. Thus the respective trunnion rides on the respective journal surfaces with the respective roller axis lying on the respective rotation axis. This one journal of each journal axis is formed at the respective journal hole with two generally semicylindrical skew surfaces spaced axially apart, centered on respective skew axes inclined to and intersecting the respective rotation axes, of at least the radius of curvature of the respective trunnion, and diametrally oppositely concave toward each other.

Abstract translation: 一种胶片处理装置具有两个间隔且大致平行的安装板，每个安装板具有一对板孔，并且板孔中的各对轴颈具有以一对轴颈轴为中心的相应的轴颈孔。 板的轴颈孔彼此同轴，两个轴颈平行。 以相应的滚子轴为中心的辊子各自具有一对以相应的滚子轴线为中心的基本上圆柱形的端部耳轴，并可旋转地容纳在相应的一个轴颈孔中，用于使各滚子在其中与其轴线与相应轴颈轴线同轴的旋转。 其中一个轴颈的轴颈被构造成使得相应的滚子能够相对于另一个滚子的限制的弹簧力而移动。 每个轴颈的至少一个轴颈在相应的轴颈孔处形成，其中两个半圆柱形轴颈表面以与相应的轴颈轴线相对的轴向间隔开，与相应的耳轴相同的曲率半径并且彼此径向相对地凹。 因此，相应的耳轴骑在相应的轴颈表面上，相应的滚子轴线位于相应的旋转轴线上。 每个轴颈的一个轴颈形成在相应的轴颈孔处，两个通常为半圆柱形的歪斜表面，轴向间隔开，中心位于相应的旋转轴线倾斜并与其相交的相应的歪斜轴线，至少相应耳轴的曲率半径， 并且彼此径向相对地凹。

公开(公告)号：US06266256B1

公开(公告)日：2001-07-24

申请号：US09701301

申请日：2000-11-28

Applicant: Klaus Lehnert ,  Henry Gueldner ,  Franz Raiser

Inventor： Klaus Lehnert ,  Henry Gueldner ,  Franz Raiser

IPC: H02M5458

CPC classification number: H02M1/425 ,  G05F1/70 ,  H05B41/28 ,  Y02B70/126

Abstract: The invention relates to a circuit for power-factor correction having a rectifier (14) which can be connected on the input side to an AC voltage source (10) and which is connected on the output side to at least one series circuit comprising a capacitor (CS1) and a diode (DS1), with the diode (DS1) being arranged such that the capacitor (CS1; CS2) cannot be charged through the diode (DS1; DS2) by the output signal from the rectifier (14), a first and a second electronic switch (T1, T2) connected in series as part of a half bridge or full bridge, each having a freewheeling diode (DF1; DF2) connected in parallel with the switch (T1; T2) and, with the [lacuna] formed by the junction point between the first and second switches (T1, T2) [lacuna] an output connection of the half bridge or full bridge is on the one hand connected via an inductance (L) to a point on the connection of the capacitor (CS1) and diode (DS1) of each series circuit comprising a capacitor (CS1) and a diode (DS1), and on the other hand forms a connection for a load (LD), and the signal at this connection during operation is at a considerably higher frequency than the output signal from the AC voltage source (10), an energy-storage capacitor (CS) which is connected in parallel with the two switches (T1, T2) and at least one further diode (DP1; DP2) which is arranged between the energy-storage capacitor (CS) and the rectifier (14) in such a manner that the energy-storage capacitor (CS) cannot be discharged through the rectifier (14).

Abstract translation: 本发明涉及一种用于功率因数校正的电路，其具有可在输入侧连接到AC电压源（10）的整流器（14），并且其连接在至少一个串联电路上，该串联电路包括电容器 （CS1）和二极管（DS1），二极管（DS1）被布置成使得电容器（CS1; CS2）不能通过来自整流器（14）的输出信号通过二极管（DS1; DS2）充电， 第一和第二电子开关（T1，T2），其串联连接为半桥或全桥的一部分，每个具有与开关（T1; T2）并联连接的续流二极管（DF1; DF2） 通过第一和第二开关（T1，T2）之间的连接点形成的空隙，半桥或全桥的输出连接一方面通过电感（L）连接到连接点 包括电容器（CS1）和二极管（DS1）的每个串联电路的电容器（CS1）和二极管（DS1），以及o 另一方面形成用于负载（LD）的连接，并且在操作期间的该连接处的信号的频率比来自交流电压源（10）的输出信号高得多，存储电容器（CS） 与两个开关（T1，T2）和至少一个另外的二极管（DP1; DP2），其以能量存储电容器（CS）不能通过整流器（14）放电的方式布置在储能电容器（CS）和整流器（14）之间。

公开(公告)号：US4577949A

公开(公告)日：1986-03-25

申请号：US678004

申请日：1984-11-30

Applicant: Erwin Geyken ,  Franz Heckl ,  Alfons Kastl ,  Klaus Lehnert ,  Rudolf Loistl

Inventor： Erwin Geyken ,  Franz Heckl ,  Alfons Kastl ,  Klaus Lehnert ,  Rudolf Loistl

IPC: G03D5/04 ,  G03D3/02 ,  G03D3/08

CPC classification number: G03D5/04

Abstract: A developing device for a photographic layer carrier, particularly a film, includes two rotary transport roller pairs transporting a film in a horizontal direction over a bath containing a processing liquid. Two liquid-admitting chambers are positioned opposite to each other in spaced relationship to form a processing space through which the film is transported. Each chamber is subdivided into two portions by a comb-like partition which loosens vortexes generated in one chamber portion upon pumping the liquid thereinto and ensures a uniform distribution of the liquid discharged into the processing space through a slot provided in the second chamber portion.

Abstract translation: 用于照相层载体，特别是薄膜的显影装置包括在包含处理液体的浴上沿水平方向传送薄膜的两个旋转输送辊对。 两个液体容纳室以间隔开的方式彼此相对设置，以形成胶片通过其运送的处理空间。 每个室通过梳状分隔分为两部分，其在泵送液体时松开在一个室部分中产生的涡流，并确保通过设置在第二室部分中的槽排出到处理空间中的液体的均匀分布。

公开(公告)号：US4514071A

公开(公告)日：1985-04-30

申请号：US496448

申请日：1983-05-20

Applicant: Horst Koninger ,  Klaus Lehnert ,  Gunter Schirk

Inventor： Horst Koninger ,  Klaus Lehnert ,  Gunter Schirk

IPC: G03D3/00 ,  F16D11/10 ,  G03D3/08 ,  G03D3/13 ,  G03B3/08

CPC classification number: G03D3/13

Abstract: A coupling device for transmitting torque from a first film transporting rack to a neighboring second film transporting rack in a developing machine has a first shaft extending outwardly from a sidewall of one of the racks, a second shaft which extends outwardly from one sidewall of the other rack and is movable into axial alignment with the first shaft, first and second gears on the respective shafts, and a sleeve having an internal gear which is in permanent mesh with one of the gears and is movable axially into and from mesh with the other gear. The sleeve has internal elastic prongs which extend into a circumferential groove of the shaft for the one gear when the internal gear meshes with the other gear.

Abstract translation: 用于将转矩从第一胶片输送架传递到显影机中的相邻的第二胶片传送架的联接装置具有从一个机架的侧壁向外延伸的第一轴，从另一个的一个侧壁向外延伸的第二轴 并且可移动地与第一轴，相应的轴上的第一和第二齿轮轴向对准，以及具有内齿轮的套筒，该内齿轮与其中一个齿轮永久啮合，并且可轴向移动到与另一齿轮啮合 。 当内齿轮与另一个齿轮啮合时，套筒具有延伸到轴的周向凹槽中的内部弹性插脚用于一个齿轮。

公开(公告)号：US4574852A

公开(公告)日：1986-03-11

申请号：US614729

申请日：1984-05-25

Applicant: Adolf Fleck ,  Alfons Kastl ,  Rudolf Loistl ,  Klaus Lehnert ,  Ernst Widemann

Inventor： Adolf Fleck ,  Alfons Kastl ,  Rudolf Loistl ,  Klaus Lehnert ,  Ernst Widemann

IPC: B67D3/00 ,  G03D3/06 ,  B65B3/04

CPC classification number: B67D3/00 ,  B67D3/0045 ,  G03D3/06 ,  B67D2210/00131

Abstract: In a feedpipe of a container for refilling a photographic developing tank with a developer radial discharge holes are provided in the region of a valve mounted at the lower end of the feedpipe extended outwardly of the container. The developer liquid is discharged into the valve and then into the tank through these radial holes. To prevent overflowing of the liquid through these holes meshed elements are inserted into the radial holes.

Abstract translation: 在用于重新填充具有显影剂的照相显影槽的容器的馈入管中，设置在安装在从容器的外侧延伸的供给管的下端的阀的区域中。 显影剂液体通过这些径向孔排出到阀中，然后进入罐中。 为了防止液体通过这些孔溢出，将网状元件插入径向孔中。

公开(公告)号：US5602018A

公开(公告)日：1997-02-11

申请号：US374770

申请日：1995-02-07

Applicant: Erhard Kopetzki ,  Klaus Lehnert

Inventor： Erhard Kopetzki ,  Klaus Lehnert

IPC: G01N33/535 ,  C07K14/37 ,  C07K14/38 ,  C07K14/41 ,  C12N9/04 ,  C12N15/09 ,  C12N15/53 ,  C12Q1/26 ,  C12R1/685 ,  C12R1/865 ,  C12N1/14 ,  C12P21/06

CPC classification number: C12N9/0006

Abstract: Hypoglycosylated recombinant glucose oxidase with a molecular weight of ca. 68-80 kDa, a specific activity of ca. 200 U/mg unit of weight, a carbohydrate portion of ca. 12% which is obtainable by expression of a recombinant DNA containing the GOD gene in the N-glycosylation-defective yeast mutants DSM 7042, DSM 7338, DSM 7160 or DSM 7340 or allelic mutant strains, fermentation and isolation of the enzyme from the culture supernatant or the cells.

Abstract translation: PCT No.PCT / EP93 / 02054 Sec。 371日期：1995年2月7日 102（e）日期1995年2月7日PCT提交1993年8月2日PCT公布。 公开号WO94 / 03608 日期：1994年2月17日分子量约为的低聚糖重组葡萄糖氧化酶 68-80 kDa，比活性约为 200 U / mg单位重量，碳水化合物部分约 通过在N-糖基化缺陷型酵母突变体DSM 7042，DSM 7338，DSM 7160或DSM 7340或等位基因突变株中表达含有GOD基因的重组DNA获得的12％，可以从培养上清液中发酵和分离酶 或细胞。

公开(公告)号：US20110321182A1

公开(公告)日：2011-12-29

申请号：US13142092

申请日：2009-12-24

Applicant: Klaus Lehnert ,  Sarah Dianne Berry ,  Russell Grant Snell ,  Alastair Kenneth Hugh MacGibbon ,  Richard Spelman ,  Alexandra Ankersmit-Udy

Inventor： Klaus Lehnert ,  Sarah Dianne Berry ,  Russell Grant Snell ,  Alastair Kenneth Hugh MacGibbon ,  Richard Spelman ,  Alexandra Ankersmit-Udy

IPC: A01K67/027 ,  C12Q1/48 ,  C12Q1/68 ,  C07H21/04 ,  C12N9/10

CPC classification number: C12Q1/6888 ,  C12Q1/6876 ,  C12Q2600/124 ,  C12Q2600/156

Abstract: The present invention is directed to mutations in the DGAT1 gene that produce an advantageous milk, tissue and/or growth rate profile in animals carrying the mutations. The present invention is also directed to methods of identifying animals carrying the mutations in order to facilitate the selection of animals with altered milk, tissue and/or growth rate traits.

Abstract translation: 本发明涉及在携带突变的动物中产生有利的牛奶，组织和/或生长速率曲线的DGAT1基因中的突变。 本发明还涉及鉴定携带突变的动物的方法，以促进选择具有改变的牛奶，组织和/或生长速度性状的动物。

公开(公告)号：US20070202097A1

公开(公告)日：2007-08-30

申请号：US10548390

申请日：2004-03-10

Applicant: Geoffrey Krissansen ,  Euphemia Leung ,  Klaus Lehnert

Inventor： Geoffrey Krissansen ,  Euphemia Leung ,  Klaus Lehnert

IPC: A61K39/395 ,  C12N5/06 ,  C07K16/28 ,  G01N33/53

CPC classification number: C07K16/2803

Abstract: The present application describes novel monoclonal antibodies, fragments and derivatives thereof which recognise mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Also described are methods which utilise the monoclonal antibodies. Further, a soluble form of MAdCAM-1 is described as well as methods which utilise its presence in a subject.

Abstract translation: 本申请描述了识别粘膜地址蛋白细胞粘附分子-1（MAdCAM-1）的新型单克隆抗体，其片段及其衍生物。 还描述了利用单克隆抗体的方法。 此外，描述了可溶形式的MAdCAM-1以及利用其存在于受试者中的方法。

公开(公告)号：US06208085B1

公开(公告)日：2001-03-27

申请号：US09572613

申请日：2000-05-17

Applicant: Klaus Lehnert ,  Henry Gueldner ,  Franz Raiser

Inventor： Klaus Lehnert ,  Henry Gueldner ,  Franz Raiser

IPC: H05B3700

CPC classification number: H02M1/425 ,  H05B41/28 ,  Y02B70/126

Abstract: The present invention relates to a circuit for power-factor correction having a bridge rectifier (18) with a first and a second input connection (14, 16) in which case an AC voltage source (10) can be arranged between the first and the second input connection (14, 16), and having a first and a second output connection (30, 32), an actuation and load circuit (24), at least one energy storage apparatus, (20; 20a; 20b), whose first connection is connected to a connection (28) in the actuation and load circuit (24), in which case the signal which can be tapped off at this connection (28) in operation is at a considerably higher frequency than the output signal from the AC voltage source (10), and an energy storage capacitor (CS), wherein the energy storage capacitor (CS) is arranged in parallel with the output connections (30, 32) of the bridge rectifier (18), and the second connection of the at least one energy storage apparatus (20; 20a; 20b) is connected to one of the two input connections (14; 16) of the bridge rectifier (18).

Abstract translation: 本发明涉及一种用于功率因数校正的电路，其具有具有第一和第二输入连接（14,16）的桥式整流器（18），在这种情况下，AC电压源（10）可以布置在第一和第二输入端 第二输入连接（14,16），并且具有第一和第二输出连接（30,32），致动和负载电路（24），至少一个能量存储装置（20; 20a; 20b），其第一 连接连接到致动和负载电路（24）中的连接（28），在这种情况下，在该连接（28）处可操作的可被分接的信号的频率比来自AC的输出信号高得多 电压源（10）和储能电容器（CS），其中所述储能电容器（CS）与所述桥式整流器（18）的输出连接（30,32）并联布置，并且所述第二连接 至少一个能量存储装置（20; 20a; 20b）连接到两个输入连接中的一个 ons（14; 16）。