-
公开(公告)号：US20100221726A1
公开(公告)日：2010-09-02
申请号：US12703046
申请日：2010-02-09
Applicant: Frederic Zenhausern , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang , Xiaojia Chen , Matthew Estes , John Lee-Edghill , Nina Moran , Andrew Hopwood , Pieris Koumi
Inventor： Frederic Zenhausern , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang , Xiaojia Chen , Matthew Estes , John Lee-Edghill , Nina Moran , Andrew Hopwood , Pieris Koumi
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/502738 , B01L7/52 , B01L7/525 , C12Q1/6806 , C25B9/00 , G01N1/10 , G01N21/01 , G01N21/6428 , G01N21/645 , G01N27/44721 , G01N27/44791 , G01N2021/6484 , G01N2201/062 , G01N2201/0846 , Y10T436/143333
Abstract: A method of analysis, instrument for analysis and device for use in such an instrument are provided, which perform a number of processes need to reach a useful result in the context of a wide variety of samples. The sequence of those processes being optimised. A device, instrument using the device and method of use are also provided which offer reliable performance of a heating based process, with minimal condensation and/or sample loss issues.
Abstract translation: 提供了一种分析方法，用于分析仪器和用于这种仪器的设备，其执行许多过程需要在各种样品的上下文中获得有用的结果。 这些过程的顺序被优化。 还提供了使用该装置和使用方法的装置，仪器，其具有基于加热的工艺的可靠性能，具有最小的冷凝和/或样品损失问题。
-
公开(公告)号：US20100213063A1
公开(公告)日：2010-08-26
申请号：US12703010
申请日：2010-02-09
Applicant: Frederic ZENHAUSERN , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang
Inventor： Frederic ZENHAUSERN , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/502738 , B01L7/52 , B01L7/525 , C12Q1/6806 , C25B9/00 , G01N1/10 , G01N21/01 , G01N21/6428 , G01N21/645 , G01N27/44721 , G01N27/44791 , G01N2021/6484 , G01N2201/062 , G01N2201/0846 , Y10T436/143333
Abstract: Analysis methods and apparatus are provided for inspecting a channel, such as a capillary electrophoresis channel, in a device. Configuration and alignment systems are provided, together with optical systems and temperature control.
Abstract translation: 提供了用于在装置中检查诸如毛细管电泳通道之类的通道的分析方法和装置。 提供了配置和对准系统，以及光学系统和温度控制。
-
公开(公告)号：US20160187293A1
公开(公告)日：2016-06-30
申请号：US14124986
申请日：2012-06-11
Applicant: Frederic ZENHAUSERN , Alan NORDQUIST , Ralf LENIGK , Cedric HURTH , Jianing YANG , Xiaojia CHEN , Matthew ESTES , John LEE-EDGHILL , Nina MORAN , Andrew HOPWOOD , Pieris KOUMI
Inventor： Frederic ZENHAUSERN , Alan NORDQUIST , Ralf LENIGK , Cedric HURTH , Jianing YANG , Xiaojia CHEN , Matthew ESTES , John LEE-EDGHILL , Nina MORAN , Andrew HOPWOOD , Pieris KOUMI
IPC: G01N27/447
CPC classification number: G01N27/44756
Abstract: An electrophoresis device where the end of the electrophoresis channel has a part that extends vertically. The electrophoresis channel includes a first access port at one end of the channel and a second port at the other end of the channel, which are in the same horizontal plane. In this way, there is a less than 0.1% hydrostatic pressure differential between two ports and the performance of the device is improved.
Abstract translation: 一种电泳装置，其中电泳通道的末端具有垂直延伸的部分。 电泳通道包括在通道的一端的第一进入口和处于相同水平面的通道的另一端的第二端口。 以这种方式，两个端口之间的静水压差小于0.1％，提高了设备的性能。
-
公开(公告)号：US20140186841A1
公开(公告)日：2014-07-03
申请号：US14034153
申请日：2013-09-23
Applicant: Frederic ZENHAUSERN , Ralf LENIGK , Jianing YANG , Zhi CAI , Alan NORDQUIST , Stanley D. SMITH , David MAGGIANO , Glen MCCARTY , Mrinalini PRASAD , Karem LINAN , Baiju THOMAS , Edward OLAYA , Cedric HURTH , Darryl COX , Mark RICHARD
Inventor： Frederic ZENHAUSERN , Ralf LENIGK , Jianing YANG , Zhi CAI , Alan NORDQUIST , Stanley D. SMITH , David MAGGIANO , Glen MCCARTY , Mrinalini PRASAD , Karem LINAN , Baiju THOMAS , Edward OLAYA , Cedric HURTH , Darryl COX , Mark RICHARD
IPC: C12Q1/68
CPC classification number: C12Q1/686 , B01L3/5027 , B01L7/52 , B01L2200/10 , B01L2200/143 , B01L2300/0816 , B01L2300/1827 , B01L2400/0421 , B01L2400/0672 , B01L2400/0677 , G01N2035/00158
Abstract: A method, system, and apparatus for analysis of a biological sample includes receiving the sample, wherein the sample includes deoxyribonucleic acid (DNA), lysing the sample to obtain access to the DNA included in the sample, purifying the DNA in the sample to isolate the DNA from other components in the sample, amplifying the DNA, separating fragments of the amplified DNA, detecting the separated fragments using laser induced fluorescence, based on the detecting, generating a profile of the DNA in the received sample, comparing the generated profile with profiles of DNA stored in a database, and upon determining that the generated profile matches one of the stored profiles, identifying the source from which the stored profile was obtained, wherein the receiving, lysing, purifying, amplifying, and detecting are performed on corresponding portions of a microfluidic device, and wherein transporting the sample and the DNA to the portions of the microfluidic device and enabling the lysing, purifying, amplifying, separating, detecting, generating, comparing, and identifying are performed automatically without user interaction.
Abstract translation: 用于分析生物样品的方法，系统和装置包括接收样品，其中样品包括脱氧核糖核酸（DNA），裂解样品以获得样品中包含的DNA，纯化样品中的DNA以分离 来自样品中的其他成分的DNA，扩增DNA，分离扩增的DNA片段，使用激光诱导的荧光检测分离的片段，基于检测，产生所接收的样品中DNA的谱，比较生成的分布与 存储在数据库中的DNA的简档，以及在确定生成的简档与所存储的简档中的一个匹配时，识别从其获得存储的简档的源，其中对相应部分执行接收，裂解，净化，放大和检测 的微流体装置，并且其中将样品和DNA运输到微流体装置的部分并且使得能够进行裂解， 净化，放大，分离，检测，生成，比较和识别是自动执行的，无需用户交互。
-
公开(公告)号：US08640555B2
公开(公告)日：2014-02-04
申请号：US12703025
申请日：2010-02-09
Applicant: Frederic Zenhausern , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang , Xiaojia Chen , John Lee-Edghill , Nina Moran , Andrew Hopwood , Pieris Koumi
Inventor： Frederic Zenhausern , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang , Xiaojia Chen , John Lee-Edghill , Nina Moran , Andrew Hopwood , Pieris Koumi
IPC: G01N1/22
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/502738 , B01L7/52 , B01L7/525 , C12Q1/6806 , C25B9/00 , G01N1/10 , G01N21/01 , G01N21/6428 , G01N21/645 , G01N27/44721 , G01N27/44791 , G01N2021/6484 , G01N2201/062 , G01N2201/0846 , Y10T436/143333
Abstract: Instruments, devices and methods of analysis are provided which fully integrate a significant number of process steps in a continuous operation. Accurate positioning and full contact between components is also provided by the relative movement the designs allow. An effect interface between a low cost disposable cartridge or device and the instrument to process it is also detailed.
Abstract translation: 提供了仪器，设备和分析方法，它们在连续操作中充分整合了大量的工艺步骤。 组件之间的精确定位和完全接触也可以通过设计允许的相对运动来提供。 低成本的一次性盒式磁盘或装置与处理它的仪器之间的效果接口也是详细的。
-
Patent Agency Ranking
公开(公告)号：US20130323737A1
公开(公告)日：2013-12-05
申请号：US13816394
申请日：2011-08-10
Applicant: Frederic Zenhausern , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang , Xiaojia Chen , Matthew Estes , John Lee-Edghill , Nina Moran , Andrew Hopwood , Pieris Koumi
Inventor： Frederic Zenhausern , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang , Xiaojia Chen , Matthew Estes , John Lee-Edghill , Nina Moran , Andrew Hopwood , Pieris Koumi
IPC: C12Q1/68 , G01N27/447
CPC classification number: C12Q1/6846 , G01N27/447 , G01N35/00029
Abstract: A method and system for analysing a sample are provided, wherein one or more process steps and/or sample processors are provided separately from the instrument, for instance a sample receiving step and sample preparation step and sample extraction step and sample retention step and/or purification step and washing step and elution step, and one or more process steps and/or sample processors provided by the instrument as an integrated set, the one or more process steps and/or sample processors provided by the instrument including a sample receiving step and amplification step and denaturing step and investigation step and detection step and results analysis step and results output step. Other combinations of the split in location of the steps are possible. The optimisation of the split allows the accurate processing by a cartridge based instrument of the sample, whilst fully interfacing with a variety of sample collection and/or preparation approaches.
Abstract translation: 提供了一种用于分析样品的方法和系统，其中与仪器分开提供一个或多个处理步骤和/或样品处理器，例如样品接收步骤和样品制备步骤以及样品提取步骤和样品保留步骤和/或 纯化步骤和洗涤步骤和洗脱步骤，以及由仪器提供的一个或多个工艺步骤和/或样品处理器作为集成组，由仪器提供的一个或多个工艺步骤和/或样品处理器，包括样品接收步骤和 扩增步骤和变性步骤及检测步骤及结果分析步骤及结果输出步骤。 步骤的位置分割的其他组合是可能的。 分割的优化允许通过样品的基于墨盒的仪器进行精确的处理，同时完全与各种样品收集和/或制备方法接口。
-
公开(公告)号：US20130137103A1
公开(公告)日：2013-05-30
申请号：US13594471
申请日：2012-08-24
Applicant: Frederic Zenhausern , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Andrew Hopwood , Pieris Koumi , Gill Tully
Inventor： Frederic Zenhausern , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Andrew Hopwood , Pieris Koumi , Gill Tully
IPC: C12Q1/68
CPC classification number: C12Q1/686 , C12Q1/6848 , C12Q2545/113
Abstract: A method of analysing a sample includes providing a first part of the sample and a second part of the sample. A first analysis is conducted on the first part of the sample and the results of the first analysis are considered. A second analysis is conducted on the second part of the sample, the second analysis being conducted according to a procedure using a value for each of one or more characteristics of the procedure. The consideration of the results of the first analysis is used to determine whether the value for one or more of the characteristics of the procedure is changed to a different value. The second analysis is started before the results of the first analysis are obtained.
-
公开(公告)号：US20100267092A1
公开(公告)日：2010-10-21
申请号：US12703037
申请日：2010-02-09
Applicant: Frederic ZENHAUSERN , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang , Xiaojia Chen , Matthew Estes , John Lee-Edghill , Nina Moran , Andrew Hopwood , Pieris Koumi , Zhi Cai
Inventor： Frederic ZENHAUSERN , Alan Nordquist , Ralf Lenigk , Cedric Hurth , Jianing Yang , Xiaojia Chen , Matthew Estes , John Lee-Edghill , Nina Moran , Andrew Hopwood , Pieris Koumi , Zhi Cai
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/502738 , B01L7/52 , B01L7/525 , C12Q1/6806 , C25B9/00 , G01N1/10 , G01N21/01 , G01N21/6428 , G01N21/645 , G01N27/44721 , G01N27/44791 , G01N2021/6484 , G01N2201/062 , G01N2201/0846 , Y10T436/143333
Abstract: A method and device structure are provided which enable an archive sample to be collected and detached relative to a device within which a series of processes, such as PCR are being provided. A chamber structure and method of use are provided in which a controlled and precise volume is obtained by control of the relative resistance to flow through various channels.
Abstract translation: 提供了一种方法和设备结构，其使得能够相对于在其中提供诸如PCR的一系列过程的设备来收集和分离归档样本。 提供了一种室结构和使用方法，其中通过控制通过各种通道的相对阻力获得受控和精确的体积。
-
公开(公告)号：US20130130365A1
公开(公告)日：2013-05-23
申请号：US13649852
申请日：2012-10-11
Applicant: Frederic ZENHAUSERN , Alan NORDQUIST , Ralf LENIGK , Cedric HURTH , Jianing YANG , Xiaojia CHEN , Matthew ESTES , John LEE-EDGHILL , Nina MORAN , Andrew HOPWOOD , Pieris KOUMI
Inventor： Frederic ZENHAUSERN , Alan NORDQUIST , Ralf LENIGK , Cedric HURTH , Jianing YANG , Xiaojia CHEN , Matthew ESTES , John LEE-EDGHILL , Nina MORAN , Andrew HOPWOOD , Pieris KOUMI
CPC classification number: B01L3/502761 , B01L3/502715 , B01L3/502738 , B01L7/52 , B01L7/525 , C12Q1/6806 , C25B9/00 , G01N1/10 , G01N21/01 , G01N21/6428 , G01N21/645 , G01N27/44721 , G01N27/44791 , G01N2021/6484 , G01N2201/062 , G01N2201/0846 , Y10T436/143333
Abstract: A method of analysis, instrument for analysis and device for use in such an instrument are provided, which perform a number of processes need to reach a useful result in the context of a wide variety of samples. The sequence of those processes being optimised. A device, instrument using the device and method of use are also provided which offer reliable performance of a heating based process, with minimal condensation and/or sample loss issues.
Abstract translation: 提供了一种分析方法，用于分析仪器和用于这种仪器的设备，其执行许多过程需要在各种样品的上下文中获得有用的结果。 这些过程的顺序被优化。 还提供了使用该装置和使用方法的装置，仪器，其具有基于加热的工艺的可靠性能，具有最小的冷凝和/或样品损失问题。
-
公开(公告)号：US20120082985A1
公开(公告)日：2012-04-05
申请号：US12672889
申请日：2008-08-11
Applicant: Frederic Zenhausern , Ralf Lenigk , Jianing Yang , Zhi Cai , Alan Nordquist , Stanley D. Smith , David Maggiano , Mrinalini Prasad , Karem Linan , Edward Olaya , Baiju Thomas , Cedric Hurth , Darryl Cox , Mark Richard , Glen Mccarty
Inventor： Frederic Zenhausern , Ralf Lenigk , Jianing Yang , Zhi Cai , Alan Nordquist , Stanley D. Smith , David Maggiano , Mrinalini Prasad , Karem Linan , Edward Olaya , Baiju Thomas , Cedric Hurth , Darryl Cox , Mark Richard , Glen Mccarty
IPC: C12Q1/68 , G01N33/53 , G01N27/447 , C12M1/34 , C12M1/40
CPC classification number: C12Q1/686 , B01L3/5027 , B01L7/52 , B01L2200/10 , B01L2200/143 , B01L2300/0816 , B01L2300/1827 , B01L2400/0421 , B01L2400/0672 , B01L2400/0677 , G01N2035/00158
Abstract: A method, system, and apparatus for analysis of a biological sample includes receiving the sample, wherein the sample includes deoxyribonucleic acid (DNA), lysing the sample to obtain access to the DNA included in the sample, purifying the DNA in the sample to isolate the DNA from other components in the sample, amplifying the DNA, separating fragments of the amplified DNA, detecting the separated fragments using laser induced fluorescence, based on the detecting, generating a profile of the DNA in the received sample, comparing the generated profile with profiles of DNA stored in a database, and upon determining that the generated profile matches one of the stored profiles, identifying the source from which the stored profile was obtained, wherein the receiving, lysing, purifying, amplifying, and detecting are performed on corresponding portions of a microfluidic device, and wherein transporting the sample and the DNA to the portions of the microfluidic device and enabling the lysing, purifying, amplifying, separating, detecting, generating, comparing, and identifying are performed automatically without user interaction.
Abstract translation: 用于分析生物样品的方法，系统和装置包括接收样品，其中样品包括脱氧核糖核酸（DNA），裂解样品以获得样品中包含的DNA，纯化样品中的DNA以分离 来自样品中的其他成分的DNA，扩增DNA，分离扩增的DNA片段，使用激光诱导的荧光检测分离的片段，基于检测，产生所接收的样品中DNA的谱，比较生成的分布与 存储在数据库中的DNA的简档，以及在确定生成的简档与所存储的简档中的一个匹配时，识别从其获得存储的简档的源，其中对相应部分执行接收，裂解，净化，放大和检测 的微流体装置，并且其中将样品和DNA运输到微流体装置的部分并且使得能够进行裂解， 净化，放大，分离，检测，生成，比较和识别是自动执行的，无需用户交互。
-
-
-
-
-
-
-
-
-
Search Results
12
records
(took 0.024 seconds)
