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公开(公告)号：US20240016147A1
公开(公告)日：2024-01-18
申请号：US18248235
申请日：2021-10-08
申请人： AgroSpheres, Inc. , Joseph FRANK , Sepehr ZOMORODI
发明人： Joseph FRANK , Sepehr ZOMORODI , Sergio Madrigal CARBALLO , Ameer Hamza SHAKEEL , Payam POURTAHERI
摘要： The present disclosure provides biodegradable, bioactive biopolymer nanocoating platforms, compositions thereof, and methods for making and producing the biopolymer nanocoating platforms. The present disclosure also provides various agricultural applications of the biodegradable, bioactive biopolymer nanocoating platforms.
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公开(公告)号：US20230189819A1
公开(公告)日：2023-06-22
申请号：US17926069
申请日：2021-05-19
申请人： AgroSpheres, Inc.
IPC分类号： A01N63/60 , C12N15/113 , C12N15/88 , A01N25/28 , A01P3/00
CPC分类号： A01N63/60 , A01N25/28 , A01P3/00 , C12N15/88 , C12N15/1137 , C12N2310/14 , C12N2310/51
摘要： It is herewith provided a biocontrol composition comprising an intact minicell comprising a nucleic acid that targets a transcript encoding a polypeptide and a method for controlling pests and pathogens with novel systems and compositions to deliver RNA molecules to a subject.
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公开(公告)号：US20240254170A1
公开(公告)日：2024-08-01
申请号：US18594957
申请日：2024-03-04
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza SHAKEEL , Sepehr ZOMORODI , Joseph Thomas FRANK , Zachery George DAVIS , Payam POURTAHERI
IPC分类号： C07K14/195 , A01N25/28 , A01N63/22 , A01N63/50 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/52 , C12N9/54 , C12N15/62 , A61K39/108 , B01F101/04
CPC分类号： C07K14/195 , A01N25/28 , A01N63/22 , A01N63/50 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/52 , C12N9/54 , C12N15/62 , A61K39/0258 , B01F2101/04 , C07K2319/705
摘要： The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and/or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and/or anucleated cells.
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公开(公告)号：US20240049706A1
公开(公告)日：2024-02-15
申请号：US18257982
申请日：2021-12-22
申请人： AgroSpheres, Inc.
摘要： The present disclosure provides compositions and methods for controlling insect pests with bioactive agents. Also, the present disclosure provides insecticidal compositions and methods of using the formulations containing minicells and bioactive agents for targeted delivery and controlled release to enhance insect control in an environment-friendly, stable and scalable manner.
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公开(公告)号：US11812743B2
公开(公告)日：2023-11-14
申请号：US16649857
申请日：2018-09-25
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza Shakeel , Zachery George Davis , Joseph Thomas Frank , Sepehr Zomorodi , Payam Pourtaheri
CPC分类号： A01N25/28 , A01N63/20 , A01N63/50 , C12N15/74 , A01N63/50 , A01N63/60 , A01N37/46 , A01N25/28 , A01N37/46 , A01N63/50 , A01N63/60 , A01N25/00 , A01N37/46 , A01N63/50 , A01N63/60
摘要： The present disclosure is generally directed to an agricultural formulation comprising an anucleated minicells and an anucleated cell-based platforms for encapsulation and scalable delivery of biologically active compounds. Disclosed herein are compositions for the stable and targeted delivery of biologically active compounds within achromosomal and/or anucleated cells onto and/or into a target cell. The present disclosure also provides methods of improving encapsulation and retention of biologically active compounds in achromosomal and/or anucleated cells and delivering biologically active compounds into a target cell.
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6.发明申请公开(公告)号：US20230044257A1
公开(公告)日：2023-02-09
申请号：US17788577
申请日：2020-12-22
申请人： AgroSpheres, Inc.
摘要： The present disclosure is generally directed to a composition comprising a minicell and an active agent and to a bacterial minicell comprising an active agent. The compositions are suitable for improving animal health, increasing live stock production, or preventing animal-to-human transmission from both domestic animals and wildlife populations. Disclosed herein are methods of preparing a minicell encapsulating an active agent, delivering an active agent to a subject, and producing an animal feed and/or an animal vaccination for improving animal health and welfare.
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公开(公告)号：US11970518B2
公开(公告)日：2024-04-30
申请号：US18191663
申请日：2023-03-28
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza Shakeel , Sepehr Zomorodi , Joseph Thomas Frank , Zachery George Davis , Payam Pourtaheri
IPC分类号： C07K14/195 , A01N25/28 , A01N63/22 , A01N63/50 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/52 , C12N9/54 , C12N15/62 , A61K39/108 , B01F101/04
CPC分类号： C07K14/195 , A01N25/28 , A01N63/22 , A01N63/50 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/52 , C12N9/54 , C12N15/62 , A61K39/0258 , B01F2101/04 , C07K2319/705
摘要： The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and/or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and/or anucleated cells.
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公开(公告)号：US20240130363A1
公开(公告)日：2024-04-25
申请号：US18396296
申请日：2023-12-26
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza SHAKEEL , Zachery George DAVIS , Joseph Thomas FRANK , Sepehr ZOMORODI , Payam POURTAHERI
摘要： The present disclosure is generally directed to an agricultural formulation comprising an anucleated minicells and an anucleated cell-based platforms for encapsulation and scalable delivery of biologically active compounds. Disclosed herein are compositions for the stable and targeted delivery of biologically active compounds within achromosomal and/or anucleated cells onto and/or into a target cell. The present disclosure also provides methods of improving encapsulation and retention of biologically active compounds in achromosomal and/or anucleated cells and delivering biologically active compounds into a target cell.
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公开(公告)号：US20230357330A1
公开(公告)日：2023-11-09
申请号：US18191663
申请日：2023-03-28
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza SHAKEEL , Sepehr ZOMORODI , Joseph Thomas FRANK , Zachery George DAVIS , Payam POURTAHERI
IPC分类号： C07K14/34 , C07K14/195 , A01N63/22 , C07K14/32 , C12N1/08 , C12N9/54 , C07K14/335 , C12N15/62 , A01N25/28 , A01N63/50 , C12N9/52
CPC分类号： C07K14/195 , A01N25/28 , A01N63/22 , A01N63/50 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/52 , C12N9/54 , C12N15/62 , A61K39/0258
摘要： The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and/or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and/or anucleated cells,
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公开(公告)号：US20230313094A1
公开(公告)日：2023-10-05
申请号：US18332559
申请日：2023-06-09
申请人： AgroSpheres, Inc.
摘要： The present disclosure provides controlled bioprocessing systems for enhanced minicell production with defined fermentation parameters and methods of said bioprocessing systems and methods for the production of minicells from said bioprocessing systems using a bioreactor or fermenter.
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