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公开(公告)号：US11812743B2
公开(公告)日：2023-11-14
申请号：US16649857
申请日：2018-09-25
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza Shakeel , Zachery George Davis , Joseph Thomas Frank , Sepehr Zomorodi , Payam Pourtaheri
CPC分类号： A01N25/28 , A01N63/20 , A01N63/50 , C12N15/74 , A01N63/50 , A01N63/60 , A01N37/46 , A01N25/28 , A01N37/46 , A01N63/50 , A01N63/60 , A01N25/00 , A01N37/46 , A01N63/50 , A01N63/60
摘要： The present disclosure is generally directed to an agricultural formulation comprising an anucleated minicells and an anucleated cell-based platforms for encapsulation and scalable delivery of biologically active compounds. Disclosed herein are compositions for the stable and targeted delivery of biologically active compounds within achromosomal and/or anucleated cells onto and/or into a target cell. The present disclosure also provides methods of improving encapsulation and retention of biologically active compounds in achromosomal and/or anucleated cells and delivering biologically active compounds into a target cell.
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公开(公告)号：US11970518B2
公开(公告)日：2024-04-30
申请号：US18191663
申请日：2023-03-28
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza Shakeel , Sepehr Zomorodi , Joseph Thomas Frank , Zachery George Davis , Payam Pourtaheri
IPC分类号： C07K14/195 , A01N25/28 , A01N63/22 , A01N63/50 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/52 , C12N9/54 , C12N15/62 , A61K39/108 , B01F101/04
CPC分类号： C07K14/195 , A01N25/28 , A01N63/22 , A01N63/50 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/52 , C12N9/54 , C12N15/62 , A61K39/0258 , B01F2101/04 , C07K2319/705
摘要： The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and/or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and/or anucleated cells.
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公开(公告)号：US11624061B2
公开(公告)日：2023-04-11
申请号：US16606595
申请日：2018-04-30
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza Shakeel , Zachery George Davis , Joseph Thomas Frank , Sepehr Zomorodi , Payam Pourtaheri
IPC分类号： C12N11/16 , C07K14/005 , C07K14/21 , C07K14/415 , C12N1/20 , C12N9/20 , C12N9/86 , C12N15/70 , C12N15/74 , B82Y5/00
摘要： The present disclosure relates to compositions of immobilized enzymes on the surface of achromosomal and/or anucleate cells and uses thereof. In particular, the present disclosure provides genetically engineered minicells with enzymes self-assembled on their surface. The immobilized enzymes on the surface of achromosomal and/or anucleate minicells, has agricultural, industrial, and environmental applications due to their improved stability durability and, reusability. Also, provided are methods for producing and purifying enzyme-immobilized minicells.
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公开(公告)号：US20240081325A1
公开(公告)日：2024-03-14
申请号：US18452223
申请日：2023-08-18
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza SHAKEEL , Zachery George Davis , Joseph Thomas Frank , Sepehr Zomorodi , Payam Pourtaheri
摘要： The present disclosure is generally directed to an agricultural formulation comprising an anucleated minicells and an anucleated cell-based platforms for encapsulation and scalable delivery of biologically active compounds. Disclosed herein are compositions for the stable and targeted delivery of biologically active compounds within achromosomal and/or anucleated cells onto and/or into a target cell. The present disclosure also provides methods of improving encapsulation and retention of biologically active compounds in achromosomal and/or anucleated cells and delivering biologically active compounds into a target cell.
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公开(公告)号：US20230265413A1
公开(公告)日：2023-08-24
申请号：US18194131
申请日：2023-03-31
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza Shakeel , Zachery George Davis , Joseph Thomas Frank , Sepehr Zomorodi , Payam Pourtaheri
IPC分类号： C12N11/16 , C07K14/005 , C07K14/21 , C07K14/415 , C12N1/20 , C12N9/20 , C12N9/86 , C12N15/70 , C12N15/74
CPC分类号： C12N11/16 , C07K14/005 , C07K14/21 , C07K14/415 , C12N1/20 , C12N9/20 , C12N9/86 , C12N15/70 , C12N15/74 , B82Y5/00
摘要： The present disclosure relates to compositions of immobilized enzymes on the surface of achromosomal and/or anucleate cells and uses thereof. In particular, the present disclosure provides genetically engineered minicells with enzymes self-assembled on their surface. The immobilized enzymes on the surface of achromosomal and/or anucleate minicells, has agricultural, industrial, and environmental applications due to their improved stability durability and, reusability. Also, provided are methods for producing and purifying enzyme-immobilized minicells.
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公开(公告)号：US11649265B2
公开(公告)日：2023-05-16
申请号：US16606601
申请日：2018-04-30
申请人： AgroSpheres, Inc.
发明人： Ameer Hamza Shakeel , Sepehr Zomorodi , Joseph Thomas Frank , Zachery George Davis , Payam Pourtaheri
IPC分类号： A01N25/26 , A01N25/28 , C07K14/195 , A01N63/22 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/54 , A01N63/50 , C12N15/62 , C12N9/52 , A61K39/108 , B01F101/04
CPC分类号： C07K14/195 , A01N25/28 , A01N63/22 , A01N63/50 , C07K14/32 , C07K14/335 , C07K14/34 , C12N1/08 , C12N9/52 , C12N9/54 , C12N15/62 , A61K39/0258 , B01F2101/04 , C07K2319/705 , A01N63/50 , A01N63/27 , A01N47/06 , A01N47/24 , A01N47/36 , A01N51/00
摘要： The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and/or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and/or anucleated cells.
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