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公开(公告)号:US20240290458A1
公开(公告)日:2024-08-29
申请号:US18582736
申请日:2024-02-21
发明人: Paul J. Coates , Stefan S. Tunev
CPC分类号: G16H20/40 , A61B5/1072
摘要: An example system includes a memory; and processing circuitry coupled to the memory, the processing circuitry configured to: receive renal arterial anatomy information of a patient; determine a renal anatomical complexity score based on the renal arterial anatomy information; determine a type of renal denervation therapy to apply to the patient based on the renal anatomical complexity score; and output an indication of the determined type of renal denervation therapy to apply to the patient.
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公开(公告)号:US20240261016A1
公开(公告)日:2024-08-08
申请号:US18609346
申请日:2024-03-19
CPC分类号: A61B18/1492 , A61N1/0551 , A61N1/3605 , A61B2018/00029 , A61B2018/00214 , A61B2018/00279 , A61B2018/00404 , A61B2018/00434 , A61B2018/00529 , A61B2018/00577 , A61B2018/1467 , A61B2090/064 , A61M25/0138 , A61M25/0141 , A61M25/0147 , A61M2025/1052
摘要: According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) are provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves within a wall of (e.g., within adventitia surrounding a lumen of) an artery or other blood vessel, such as the common hepatic artery.
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公开(公告)号:US12035959B2
公开(公告)日:2024-07-16
申请号:US17314894
申请日:2021-05-07
发明人: Sowmya Ballakur , Robert J. Beetel , Paul Friedrichs , David Herzfeld , Andrew Wu , Denise Zarins , Mark S. Leung
CPC分类号: A61B18/1206 , A61B18/10 , A61B18/1492 , A61F7/12 , A61B2017/00075 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00672 , A61B2018/00678 , A61B2018/00702 , A61B2018/00761 , A61B2018/00791 , A61B2018/00797 , A61B2018/00815 , A61B2018/00821 , A61B2018/00863 , A61B2018/00875 , A61F2007/0093 , A61F2007/126
摘要: The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.
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公开(公告)号:US20240206968A1
公开(公告)日:2024-06-27
申请号:US18598108
申请日:2024-03-07
发明人: Scott Raymond Smith
IPC分类号: A61B18/14 , A61B8/08 , A61B8/12 , A61B17/00 , A61B17/122 , A61B17/32 , A61B18/00 , A61B18/02 , A61B18/04 , A61B18/06 , A61B18/16 , A61B18/18 , A61B18/22 , A61B18/24 , A61M25/01 , A61M25/09 , A61N7/00
CPC分类号: A61B18/1492 , A61B17/122 , A61B17/320068 , A61B18/02 , A61B18/06 , A61B18/16 , A61M25/0147 , A61B8/12 , A61B8/485 , A61B2017/00402 , A61B2017/00867 , A61B2017/320069 , A61B2018/00023 , A61B2018/00047 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00279 , A61B2018/00285 , A61B2018/00404 , A61B2018/00434 , A61B2018/00529 , A61B2018/00577 , A61B2018/00821 , A61B2018/00875 , A61B2018/0212 , A61B2018/048 , A61B2018/068 , A61B2018/1425 , A61B2018/1435 , A61B2018/1467 , A61B2018/1475 , A61B18/1815 , A61B2018/1861 , A61B18/22 , A61B18/24 , A61B2218/007 , A61M25/09 , A61N2007/0021 , A61N2007/0043
摘要: According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) or other tissue are provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves surrounding (e.g., within adventitia of or within perivascular space of) an artery or other blood vessel, such as the common hepatic artery.
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公开(公告)号:US20240206966A1
公开(公告)日:2024-06-27
申请号:US18556777
申请日:2022-04-26
发明人: Gary Kelly , Brian J. Castelli , Brian Dowling , Cian Michael Ryan , Jaclyn N. Kawwas , Manoj Kumar Singh
CPC分类号: A61B18/1492 , A61M25/0041 , A61M25/0043 , A61M25/0113 , A61M25/0136
摘要: Various embodiments of catheters are disclosed. In one aspect, a catheter includes a catheter shaft actuator (e.g., a catheter handle) and a catheter shaft, where the working length of the catheter shaft is adjustable, and where this working length is defined between distal ends of the catheter shaft actuator and catheter shaft, respectively. In another aspect, a catheter includes a catheter handle and a shuttle to which a catheter shaft may be secured, with the shuttle being movable relative to at least a distal end of the catheter handle. In another aspect, a catheter includes a catheter shaft, a catheter shaft actuator that is movably mounted on the catheter shaft, and a housing, where the catheter shaft extends proximally to the housing, where a generator cable extends proximally from the housing, and where the catheter shaft actuator is disposable distally of the housing along the catheter shaft.
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公开(公告)号:US20240156508A1
公开(公告)日:2024-05-16
申请号:US18549703
申请日:2022-04-11
发明人: Manoj Kumar Singh
CPC分类号: A61B18/06 , A61B2018/0022 , A61B2018/00577 , A61B2018/143
摘要: Various embodiments chemical ablation therapy delivery systems are disclosed herein. One aspect of such a system utilizes an expandable element, at least one guide tube that is fixed, secured, or otherwise anchored to the expandable element, and a needle that is movably disposed within the guide tube. Another aspect of such a system utilizes an expandable element, at least one fluid delivery tube or ablation conduit that is fixed, secured, or otherwise anchored to the expandable element, and at least one injector that extends from an outer perimeter of the corresponding fluid delivery tube, is fluidly interconnected with the corresponding fluid delivery tube, and protrudes beyond an outer perimeter of the expandable element at least when in its deployed state or configuration. Yet another aspect of such a system includes an inflatable tube, where at least one injector is separately attached to the inflatable tube and is fluidly connected with an interior space of the inflatable tube.
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公开(公告)号:US20240138896A1
公开(公告)日:2024-05-02
申请号:US18399843
申请日:2023-12-29
IPC分类号: A61B18/02 , A61B17/00 , A61B17/32 , A61B18/04 , A61B18/06 , A61B18/14 , A61B18/18 , A61B18/20 , A61B18/24 , A61K9/00 , A61K31/045 , A61K31/05 , A61K31/395 , A61K33/30 , A61K45/06 , A61M5/14 , A61N1/05 , A61N5/00 , A61N7/00
CPC分类号: A61B18/02 , A61B17/00 , A61B17/00234 , A61B17/32 , A61B18/04 , A61B18/06 , A61B18/1492 , A61B18/1815 , A61B18/20 , A61B18/24 , A61K9/0019 , A61K31/045 , A61K31/05 , A61K31/395 , A61K33/30 , A61K45/06 , A61M5/14 , A61N1/0551 , A61N5/00 , A61N7/00 , A61B2017/320069 , A61B2017/32007 , A61N7/022
摘要: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
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公开(公告)号:US20240130774A1
公开(公告)日:2024-04-25
申请号:US18399827
申请日:2023-12-29
IPC分类号: A61B18/02 , A61B17/00 , A61B17/32 , A61B18/04 , A61B18/06 , A61B18/14 , A61B18/18 , A61B18/20 , A61B18/24 , A61K9/00 , A61K31/045 , A61K31/05 , A61K31/395 , A61K33/30 , A61K45/06 , A61M5/14 , A61N1/05 , A61N5/00 , A61N7/00
CPC分类号: A61B18/02 , A61B17/00 , A61B17/00234 , A61B17/32 , A61B18/04 , A61B18/06 , A61B18/1492 , A61B18/1815 , A61B18/20 , A61B18/24 , A61K9/0019 , A61K31/045 , A61K31/05 , A61K31/395 , A61K33/30 , A61K45/06 , A61M5/14 , A61N1/0551 , A61N5/00 , A61N7/00 , A61B2017/320069 , A61B2017/32007 , A61N7/022
摘要: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.
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公开(公告)号:US11844558B2
公开(公告)日:2023-12-19
申请号:US17815509
申请日:2022-07-27
CPC分类号: A61B18/00 , A61F7/12 , G16H20/40 , G16H20/60 , A61B18/1492 , A61B2017/320069 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61F2007/126
摘要: Methods for treating eating disorders and for reducing a risk associated with developing an eating disorder in patients via therapeutic renal neuromodulation and associated systems. Renal sympathetic nerve activity can be attenuated to improve a patient's eating disorder status or risk of developing an eating disorder. The attenuation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly configured to modulate the renal sympathetic nerve.
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公开(公告)号:US11801085B2
公开(公告)日:2023-10-31
申请号:US16938404
申请日:2020-07-24
发明人: Andrew Wu , Benjamin J. Clark , Erik Thai , Nicolas Zadno , Denise Zarins
CPC分类号: A61B18/1233 , A61B18/12 , A61B18/1206 , A61B18/14 , A61B18/1492 , A61F7/007 , A61F7/12 , A61N1/403 , A61B2017/00084 , A61B2018/00214 , A61B2018/00279 , A61B2018/00404 , A61B2018/00577 , A61B2018/00636 , A61B2018/00666 , A61B2018/00702 , A61B2018/00714 , A61B2018/00755 , A61B2018/00779 , A61B2018/00791 , A61B2018/00875 , A61B2018/1475 , A61F2007/126
摘要: Methods and system are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. In some embodiments, thermally-induced renal neuromodulation is achieved via delivery of a pulsed thermal therapy.
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