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公开(公告)号：US10665001B2
公开(公告)日：2020-05-26
申请号：US15003559
申请日：2016-01-21
Applicant: California Institute of Technology
Inventor： Roarke W. Horstmeyer , Changhuei Yang
Abstract: Certain aspects pertain to Fourier ptychographic tomographic systems and methods for acquiring a plurality of uniquely illuminated intensity measurements based on light passing through a thick sample from plane wave illumination at different angles and for constructing three-dimensional tomographic data of the thick sample by iteratively determining three-dimensional tomographic data in the Fourier domain that is self-consistent with the uniquely illuminated intensity measurements.
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公开(公告)号：US10537226B2
公开(公告)日：2020-01-21
申请号：US14580074
申请日：2014-12-22
Applicant: California Institute of Technology , City of Hope
Inventor： Chao Han , Lily L Lai , Jiangtao Huangfu , Changhuei Yang
Abstract: A rotational scanning endoscope for rotationally scanning to capture a circumferential image
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公开(公告)号：US20190049712A1
公开(公告)日：2019-02-14
申请号：US16162271
申请日：2018-10-16
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
Abstract: Certain aspects pertain to multi-well systems, devices, and methods of Fourier ptychographic and fluorescence imaging.
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公开(公告)号：US10168525B2
公开(公告)日：2019-01-01
申请号：US15007159
申请日：2016-01-26
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
Abstract: Certain aspects pertain to multi-well systems, devices, and methods of Fourier ptychographic and fluorescence imaging.
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公开(公告)号：US20180316855A1
公开(公告)日：2018-11-01
申请号：US15963966
申请日：2018-04-26
Applicant: California Institute of Technology
Inventor： Xiaoze Ou , Roarke W. Horstmeyer , Guoan Zheng , Changhuei Yang
IPC: H04N5/232 , G02B27/58 , G02B27/10 , G02B21/36 , H04N5/32 , G02B21/08 , G02B21/06 , H04N5/225 , G02B21/12
CPC classification number: H04N5/23232 , G02B21/06 , G02B21/084 , G02B21/086 , G02B21/125 , G02B21/361 , G02B21/367 , G02B27/1066 , G02B27/58 , H04N5/2256 , H04N5/32
Abstract: Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier ptychographic imaging systems.
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Patent Agency Ranking
公开(公告)号：US20180307017A1
公开(公告)日：2018-10-25
申请号：US15959050
申请日：2018-04-20
Applicant: California Institute of Technology
Inventor： Roarke W. Horstmeyer , Guoan Zheng , Xiaoze Ou , Changhuei Yang
CPC classification number: G02B21/008 , G01N23/205 , G01T1/185 , G01T3/008 , G02B21/0032 , G02B21/0048 , G02B21/0056 , G02B21/006 , G02B21/16 , G02B21/367 , G02B27/46 , G02B27/58
Abstract: Certain aspects pertain to aperture-scanning Fourier ptychographic imaging devices comprising an aperture scanner that can generate an aperture at different locations at an intermediate plane of an optical arrangement, and a detector that can acquire lower resolution intensity images for different aperture locations, and wherein a higher resolution complex image may be constructed by iteratively updating regions in Fourier space with the acquired lower resolution images.
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公开(公告)号：US09993149B2
公开(公告)日：2018-06-12
申请号：US15081659
申请日：2016-03-25
Applicant: California Institute of Technology
Inventor： Jaebum Chung , Roarke W. Horstmeyer , Changhuei Yang
CPC classification number: A61B3/0025 , A61B3/12 , A61B3/1225 , A61B3/14 , G02B26/02 , G02B26/0833 , G06T7/0012 , G06T11/003 , G06T2207/10004 , G06T2207/30041
Abstract: Certain embodiments pertain to Fourier ptychographic retinal imaging methods and systems that focus on a retina of an eye to acquire a sequence of raw retinal images, construct a full-resolution, complex retinal image from the sequence of raw retinal image and correct the aberration in the full-resolution, complex retinal image to generate a substantially aberration-free retinal image.
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公开(公告)号：US20170299854A1
公开(公告)日：2017-10-19
申请号：US15636494
申请日：2017-06-28
Applicant: California Institute of Technology
Inventor： Jinho Kim , Changhuei Yang
CPC classification number: G02B21/365 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G01N2021/6478 , G01N2201/0446 , G02B13/0095 , G02B21/0076 , G02B21/16 , G02B21/367 , H04N5/22541 , H04N5/2256 , H04N5/2258
Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.
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公开(公告)号：US20170273551A1
公开(公告)日：2017-09-28
申请号：US15081659
申请日：2016-03-25
Applicant: California Institute of Technology
Inventor： Jaebum Chung , Roarke W. Horstmeyer , Changhuei Yang
CPC classification number: A61B3/0025 , A61B3/12 , A61B3/1225 , A61B3/14 , G02B26/02 , G02B26/0833 , G06T7/0012 , G06T11/003 , G06T2207/10004 , G06T2207/30041
Abstract: Certain embodiments pertain to Fourier ptychographic retinal imaging methods and systems that focus on a retina of an eye to acquire a sequence of raw retinal images, construct a full-resolution, complex retinal image from the sequence of raw retinal image and correct the aberration in the full-resolution, complex retinal image to generate a substantially aberration-free retinal image.
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90.发明申请OPTICAL FOCUSING INSIDE SCATTERING MEDIA WITH TIME-REVERSED ULTRASOUND MICROBUBBLE ENCODED (TRUME) LIGHT 审中-公开光学聚焦内置散射介质与时间反射超声波编码（TRUME）灯公开(公告)号：US20160363527A1
公开(公告)日：2016-12-15
申请号：US15181160
申请日：2016-06-13
Applicant: California Institute of Technology
Inventor： Haowen Ruan , Mooseok Jang , Changhuei Yang , Daifa Wang
CPC classification number: G01N15/14 , A61B5/00 , A61B5/0097 , A61B8/0891 , A61B8/481 , G01N21/453 , G01N21/4788 , G01N21/4795 , G01N2021/473
Abstract: A method for irradiating scattering medium, including modifying a particle's response to electromagnetic radiation irradiating the particle in a scattering medium, wherein the electromagnetic radiation is scattered by the scattering medium, and modulated by the modifying, into scattered electromagnetic radiation comprising a scattered field; forming a phase conjugate field, wherein the phase conjugate field is a phase conjugate of the scattered field; and irradiating the scattering medium with the phase conjugate field, wherein the phase conjugate field forms a focus at a target defined by the particle.
Abstract translation: 一种用于照射散射介质的方法，包括改变颗粒对散射介质中照射颗粒的电磁辐射的响应，其中电磁辐射被散射介质散射并通过修改调制成包括散射场的散射电磁辐射; 形成相位共轭场，其中所述相位共轭场是所述散射场的相位共轭; 以及用所述相位共轭场辐射所述散射介质，其中所述相位共轭场在由所述粒子限定的目标处形成焦点。
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