公开(公告)号：US07226410B2

公开(公告)日：2007-06-05

申请号：US10310365

申请日：2002-12-05

申请人： Gary L. Long

发明人： Gary L. Long

IPC分类号： A61B1/01 ,  A61M25/082

CPC分类号： A61B1/31 ,  A61B1/00156 ,  A61B1/018 ,  A61B1/041 ,  A61B1/05 ,  A61M25/0105 ,  A61M25/0116 ,  A61M2210/1042 ,  A61M2210/106 ,  A61M2210/1064 ,  A61M2210/1067

摘要： A medical device for performing medical procedures inside a lumen (such as the GI tract) of a patient is provided comprising a capsule, a cable, and a propulsion means. The cable can have one end anchored to the patient, and can extend from this anchored portion to the capsule. The cable can include a loop forward (distal) of the capsule in the GI tract. The propulsion means is operably connected to the cable to vary the length of cable between the anchored end and the capsule, so that the capsule is repositioned inside the GI tract of the patient.

摘要翻译： 提供了一种用于在患者的内腔（例如GI道）内进行医疗处理的医疗装置，其包括胶囊，电缆和推进装置。 电缆可以具有锚定到患者的一端，并且可以从该锚定部分延伸到胶囊。 电缆可以包括在胃肠道中前进（远端）胶囊的环。 推进装置可操作地连接到电缆以改变锚固端和胶囊之间的电缆的长度，使得胶囊重新定位在患者的胃肠道内。

公开(公告)号：US20060240096A1

公开(公告)日：2006-10-26

申请号：US11408238

申请日：2006-04-21

申请人： Chad Kugler ,  Robert Atkinson ,  Peter Keith

发明人： Chad Kugler ,  Robert Atkinson ,  Peter Keith

IPC分类号： A61K9/48 ,  A61N1/30

CPC分类号： A61M31/002 ,  A61K9/0009 ,  A61K9/0012 ,  A61K9/0065 ,  A61K9/4808 ,  A61K9/4816 ,  A61K9/4891 ,  A61K31/745 ,  A61K31/75 ,  A61K31/765 ,  A61K31/78 ,  A61K31/785 ,  A61K33/00 ,  A61M2210/1042 ,  A61N5/062

摘要： Devices and methods for less invasively treating the gastrointestinal system, such as the intestinal mucosa of the small bowel. Embodiments described herein may be used to reduce caloric absorption and effectuate weight loss, for example.

摘要翻译： 用于较少侵入性治疗胃肠系统的装置和方法，例如小肠的肠粘膜。 例如，本文所述的实施方案可用于降低热量吸收和实现减肥。

公开(公告)号：US20050147559A1

公开(公告)日：2005-07-07

申请号：US11056756

申请日：2005-02-11

申请人： Thomas von Alten

发明人： Thomas von Alten

IPC分类号： A61B5/07 ,  A61J3/00 ,  A61K9/00 ,  A61K9/48 ,  A61M5/172 ,  A61M31/00 ,  G11B9/00 ,  A61K49/00 ,  A61K9/22

CPC分类号： A61J3/007 ,  A61B5/073 ,  A61K9/0009 ,  A61K9/4808 ,  A61M5/1723 ,  A61M31/00 ,  A61M31/002 ,  A61M2205/3523 ,  A61M2210/1042 ,  B82Y10/00 ,  G11B9/14

摘要： The present invention provides a swallowable internal drug medical device. The device includes a swallowable capsule. A sensing module is disposed in the capsule. A bioactive substance dispenser is disposed in the capsule. A memory and logic component is disposed in the capsule and in communication with the sensing module and the dispenser.

摘要翻译： 本发明提供一种可吞咽的内部药物医疗装置。 该装置包括吞咽胶囊。 感测模块​​设置在胶囊中。 生物活性物质分配器设置在胶囊中。 存储器和逻辑部件设置在胶囊中并与感测模块和分配器通信。

公开(公告)号：US20050075559A1

公开(公告)日：2005-04-07

申请号：US10607721

申请日：2003-06-27

申请人： Peter Houzego ,  Peter Morgan ,  Peter Hirst ,  Duncan Westland ,  Ian Wilding

发明人： Peter Houzego ,  Peter Morgan ,  Peter Hirst ,  Duncan Westland ,  Ian Wilding

IPC分类号： A61F2/02 ,  A61K9/22 ,  A61M25/01 ,  A61M31/00 ,  A61M36/04 ,  A61B5/05

CPC分类号： A61M31/002 ,  A61F2250/0002 ,  A61J3/07 ,  A61M25/01 ,  A61M31/00 ,  A61M2205/3523 ,  A61M2210/1042

摘要： An ingestible device for delivering a substance to a chosen location in the GI tract of a mammal includes a receiver of electromagnetic radiation for powering an openable part of the device to an opened position for dispensing of the substance. The receiver includes a coiled wire that couples the energy field, the wire having an air or ferrite core. In a further embodiment the invention includes an apparatus for generating the electromagnetic radiation, the apparatus including one or more pairs of field coils supported in a housing. The device optionally includes a latch defined by a heating resistor and a fusible restraint. The device may also include a flexible member that may serve one or both the functions of activating a transmitter circuit to indicate dispensing of the substance; and restraining of a piston used for expelling the substance.

摘要翻译： 用于将物质递送到哺乳动物胃肠道中的选定位置的可摄取装置包括用于向设备的可打开部分供电以用于分配物质的打开位置的电磁辐射接收器。 接收器包括耦合能量场的线圈，该线具有空气或铁氧体磁芯。 在另一实施例中，本发明包括一种用于产生电磁辐射的装置，该装置包括支撑在壳体中的一对或多对场线圈。 该装置可选地包括由加热电阻器和易熔制约器限定的闩锁。 该装置还可以包括柔性构件，其可以用于激活发射器电路以指示物质的分配的一个或两个功能; 并限制用于排出物质的活塞。

公开(公告)号：US20040214311A1

公开(公告)日：2004-10-28

申请号：US10766861

申请日：2004-01-30

发明人： Mark M. Levy

IPC分类号： C12M001/34

CPC分类号： A61K9/0053 ,  A61K45/06 ,  A61M1/1678 ,  A61M1/28 ,  A61M1/3679 ,  A61M2202/0014 ,  A61M2202/0057 ,  A61M2202/0064 ,  A61M2202/0445 ,  A61M2202/20 ,  A61M2210/1042

摘要： An ingestible device is provided. The ingestible device comprises a sink mechanism, for generating net influx of at least one constituent-of-interest present in a gastrointestinal tract of an individual, and a confining mechanism for confining the sink mechanism in a predetermined confinement.

摘要翻译： 提供可摄取的装置。 可摄取装置包括宿机构，用于产生存在于个体的胃肠道中的至少一种感兴趣的成分的净流入，以及用于将宿机构限制在预定限制内的约束机构。

公开(公告)号：US06699179B2

公开(公告)日：2004-03-02

申请号：US10020913

申请日：2001-12-19

申请人： Jeffrey Michael Wendlandt

发明人： Jeffrey Michael Wendlandt

IPC分类号： A61B101

CPC分类号： A61B1/31 ,  A61B1/00 ,  A61B1/00156 ,  A61B1/0052 ,  A61B1/0058 ,  A61B1/018 ,  A61B1/053 ,  A61B1/2733 ,  A61M25/0116 ,  A61M25/0119 ,  A61M2210/1042

摘要： A self propelling catheter introducer system for exploring a body cavity is disclosed which includes a flexible tubular catheter, a propulsion section and a steering section located near the end of the catheter that is introduced in a body cavity. The propulsion section includes a flexible everting tube designed to push the catheter from inside the body cavity. The catheter can thus be made very flexible in bending, and a larger diameter catheter can be used without discomfort to the patient.

摘要翻译： 公开了一种用于探索体腔的自推进导管导引器系统，其包括柔性管状导管，推进部分和位于导管端部附近的转向部分，导管部分引入体腔。 推进部分包括设计成从体腔内部推动导管的柔性护套管。 因此，导管可以在弯曲时变得非常柔性，并且可以使用更大直径的导管而不使患者不舒适。

公开(公告)号：US20020055734A1

公开(公告)日：2002-05-09

申请号：US09742936

申请日：2000-12-20

发明人： Peter J. Houzego ,  Peter N. Morgan ,  Peter H. Hirst ,  Duncan J. Westland ,  Ian R. Wilding

IPC分类号： A61M005/14

CPC分类号： A61M31/002 ,  A61F2250/0002 ,  A61J3/07 ,  A61M25/01 ,  A61M31/00 ,  A61M2205/3523 ,  A61M2210/1042

摘要： An ingestible device for delivering a substance to a chosen location in the GI tract of a mammal includes a receiver of electromagnetic radiation for powering an openable part of the device to an opened position for dispensing of the substance. The receiver includes a coiled wire that couples the energy field, the wire having an air or ferrite core. In a further embodiment the invention includes an apparatus for generating the electromagnetic radiation, the apparatus including one or more pairs of field coils supported in a housing. The device optionally includes a latch defined by a heating resistor and a fusible restraint. The device may also include a flexible member that may serve one or both the functions of activating a transmitter circuit to indicate dispensing of the substance; and restraining of a piston used for expelling the substance.

摘要翻译： 用于将物质递送到哺乳动物胃肠道中的选定位置的可摄取装置包括用于向设备的可打开部分供电以用于分配物质的打开位置的电磁辐射接收器。 接收器包括耦合能量场的线圈，该线具有空气或铁氧体磁芯。 在另一实施例中，本发明包括一种用于产生电磁辐射的装置，该装置包括支撑在壳体中的一对或多对场线圈。 该装置可选地包括由加热电阻器和易熔制约器限定的闩锁。 该装置还可以包括柔性构件，其可以用于激活发射器电路以指示物质的分配的一个或两个功能; 并限制用于排出物质的活塞。

公开(公告)号：US12121647B2

公开(公告)日：2024-10-22

申请号：US17183542

申请日：2021-02-24

申请人： Boston Scientific Scimed, Inc.

发明人： Martyn Folan ,  Matthew Montague ,  Michael Walsh ,  Louis McNern ,  John T. Favreau ,  Shawn Ryan

IPC分类号： A61M1/00 ,  A61B17/00 ,  A61F2/00 ,  A61F2/04

CPC分类号： A61M1/90 ,  A61B17/0057 ,  A61F2/04 ,  A61B2017/0061 ,  A61B2017/00632 ,  A61F2002/0081 ,  A61F2002/045 ,  A61F2250/0059 ,  A61M2210/1042

摘要： A medical system includes a porous body positioned at a target site within a subject, a tube including a wall defining a tube lumen, where the tube is connected to the porous body at a first end of the tube, and a sealing device to seal the target site from a body lumen. When the sealing device seals the target site from the body lumen, the tube extends from the target site into the body lumen.

公开(公告)号：US12053606B2

公开(公告)日：2024-08-06

申请号：US17007086

申请日：2020-08-31

申请人： Celero Systems, Inc.

发明人： Benjamin D. Pless ,  Daniel Bacher

IPC分类号： A61M31/00 ,  A61K9/00 ,  A61K9/48 ,  A61K31/485 ,  A61P25/36

CPC分类号： A61M31/00 ,  A61K9/0065 ,  A61K9/4808 ,  A61K31/485 ,  A61P25/36 ,  A61M2205/18 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3523 ,  A61M2205/3553 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2210/1042 ,  A61M2230/04 ,  A61M2230/06 ,  A61M2230/20 ,  A61M2230/30 ,  A61M2230/42 ,  A61M2230/50 ,  A61M2230/63 ,  A61M2230/65

摘要： An opioid overdose rescue device is provided that includes an ingestible capsule. Within the ingestible capsule is a non-refillable drug dispenser comprising an opioid antidote and at least one sensor configured to detect at least one physiological parameter indicative of an opioid overdose. A controller is also contained within the ingestible capsule and is operatively coupled to the drug dispenser and the least one sensor. The controller is configured to receive a signal detected by the least one sensor of the at least one physiological parameter to actuate release of the opioid antidote from the drug dispenser into the intestine of the patient upon a determination that the at least one physiological parameter falls outside a threshold value or range for the at least one physiological parameter indicating that an opioid overdose has been detected.

公开(公告)号：US20240149031A1

公开(公告)日：2024-05-09

申请号：US18549032

申请日：2021-03-05

申请人： BITherapeutics Inc.

发明人： Jin Taeg CHO ,  Da In JANG

IPC分类号： A61M31/00

CPC分类号： A61M31/002 ,  A61M2210/1042 ,  A61M2230/005

摘要： A swallowable oral drug delivery device comprises: a driving part including an actuator, and a cylinder linearly moving by means of the actuator; a drug accommodation part including a first chamber for accommodating a piston linked with the cylinder to linearly move and an inactivated first drug, a second chamber for accommodating a second drug activating the first drug, a separation membrane for isolating the first chamber from the second chamber, and an outlet membrane for closing an outlet allowing either the first chamber or the second chamber to communicate with an external environment; a sensing part for identifying the movement or position of the drug delivery device; and a control part for receiving a signal provided from the sensing part, and controlling the operation of the actuator on the basis of the signal.