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    HEMOSTATIC COMPOSITION, APPARATUS, AND METHODS
    77.
    发明申请
    HEMOSTATIC COMPOSITION, APPARATUS, AND METHODS 有权
    HEMOSTATIC COMPOSITION，APPARATUS和METHODS

    公开(公告)号：US20120107388A1

    公开(公告)日：2012-05-03

    申请号：US13243780

    申请日：2011-09-23

    申请人： Natalia Dmitrievna Oltarshevskaya ,  Larisa Borisovna Savilova ,  German Evseevich Krichevsky

    发明人： Natalia Dmitrievna Oltarshevskaya ,  Larisa Borisovna Savilova ,  German Evseevich Krichevsky

    IPC分类号： A61K9/70 ,  A61F13/00 ,  A61P17/02 ,  A61K36/28 ,  A61P7/04

    CPC分类号： A61K36/28 ,  A61F13/00 ,  A61K31/722 ,  A61K36/185 ,  A61K45/06 ,  A61K2300/00 ,  A61L15/40 ,  A61L2400/04

    摘要： The present invention provides hemostatic compositions comprising components of the flowers of pharmaceutical chamomile (Chamomilla recutita) and the leaves of dioecious nettle (Urtica dioica). Further inclusion of a biocompatible polymeric base, particularly an alignate, generates a composition with excellent and broad spectrum hemostatic capabilities, with concurrent antiseptic and anti-inflammatory properties. The invention further provides methods of using the inventive compositions in to reduce or stop bleeding, as well as a variety of apparatuses useful in hemostatic contexts that incorporate the inventive compositions. In one particular embodiment, the invention provides hemostatic dressings in which a polymeric layer incorporating chamomile and nettle components is applied to a textile or fabric material, for example a non-woven viscose.

    摘要翻译： 本发明提供了包含药用洋甘菊（Chamomilla recutita）的花的成分和异性荨麻（Urtica dioica）的叶子的止血组合物。 进一步包含生物相容性聚合物基质，特别是对齐物，产生具有优异和广谱止血能力的组合物，具有同时的消毒和抗炎特性。 本发明还提供使用本发明组合物来减少或停止出血的方法，以及可用于结合本发明组合物的止血背景中的多种装置。 在一个具体实施方案中，本发明提供了止血敷料，其中将含有洋甘菊和荨麻成分的聚合物层施加到织物或织物材料，例如非织造粘胶。

    Platelet gel comprising platelet-rich plasma, platelet activator and polymer
    78.
    发明授权
    Platelet gel comprising platelet-rich plasma, platelet activator and polymer 失效
    血小板凝胶包含富血小板血浆，血小板活化剂和聚合物

    公开(公告)号：US08168230B2

    公开(公告)日：2012-05-01

    申请号：US11313781

    申请日：2005-12-22

    申请人： Virgilio Evangelista

    发明人： Virgilio Evangelista

    IPC分类号： A61K35/14 ,  A61K9/00 ,  A01N63/00 ,  A61F2/00

    CPC分类号： A61L24/0005 ,  A61K35/16 ,  A61L15/40 ,  A61L26/0057 ,  A61K2300/00

    摘要： A semi-synthetic platelet gel comprising a platelet-rich plasma, at least one platelet activator, and a biocompatible polymer selected from the group comprising carbomers, polyalkylene glycols, poloxamers, polyesters, polyethers, polyanhydrides, polyacrylates, polyvinyl acetates, polyvinyl pyrrolidones, polysaccharides, and derivatives thereof. A method for preparing a semi-synthetic platelet gel comprising the steps of (a) mixing a platelet-rich plasma with at least one platelet activator, and, before the start of clot formation, (b) adding the mixture thus obtained to a biocompatible polymer selected from the group comprising carbomers, polyalkylene glycols, poloxamers, polyesters, polyethers, polyanhydrides, polyacrylates, polyvinyl acetates, polyvinyl pyrrolidones, polysaccharides, and derivatives thereof.

    摘要翻译： 一种半合成血小板凝胶，其包含富含血小板的血浆，至少一种血小板活化剂和选自包含卡波姆，聚亚烷基二醇，泊洛沙姆，聚酯，聚醚，聚酐，聚丙烯酸酯，聚乙酸乙烯酯，聚乙烯吡咯烷酮，多糖的生物相容性聚合物 及其衍生物。 一种制备半合成血小板凝胶的方法，包括以下步骤：（a）将富含血小板的血浆与至少一种血小板活化剂混合，并且在凝块形成开始之前，（b）将由此获得的混合物加入生物相容性 选自卡波姆，聚亚烷基二醇，泊洛沙姆，聚酯，聚醚，聚酐，聚丙烯酸酯，聚乙酸乙烯酯，聚乙烯吡咯烷酮，多糖及其衍生物的聚合物。

    Biodegradable wound care products with biocompatible artificial skin treatment
    79.
    发明申请
    Biodegradable wound care products with biocompatible artificial skin treatment 审中-公开
    具有生物相容性人造皮肤治疗的可生物降解伤口护理产品

    公开(公告)号：US20120015022A1

    公开(公告)日：2012-01-19

    申请号：US12803992

    申请日：2010-07-13

    申请人： Kenneth P. Glynn

    发明人： Kenneth P. Glynn

    IPC分类号： A61K9/70 ,  A61K36/03 ,  A61P17/02 ,  A61K36/02

    CPC分类号： A61F13/00063 ,  A61F2013/00221 ,  A61K36/03 ,  A61L15/40 ,  A61L15/64 ,  A61L27/60

    摘要： A biodegradable wound care product with biocompatible artificial skin treatment is described. It includes a biodegradable bandage support member and a biodegradable adhesive on at least a portion thereof. The support member is made of a biodegradable material, such as natural or artificial textiles, plastics or papers. The biodegradable actives carrier is attached to a portion of the biodegradable bandage support member and is a synthetic or natural biodegradable adhesive or a combination thereof. The active ingredient located on the biodegradable actives carrier includes a layer of biocompatible algae artificial skin including sterilized water and at least sixty percent by weight of reconstituted seaweed. Laminaria seaweed may be used for its desirable polyfucose sulfate content. The active ingredient is prepared by first drying the raw materials, converting the raw materials to a powder and then reconstituting the powder with sterilizes water and other possible actives and/or inerts.

    摘要翻译： 描述了具有生物相容性人造皮肤治疗的可生物降解伤口护理产品。 它在其至少一部分上包括可生物降解的绷带支撑构件和可生物降解的粘合剂。 支撑构件由可生物降解的材料制成，例如天然或人造纺织品，塑料或纸。 可生物降解的活性物质载体连接到可生物降解的绷带支撑构件的一部分上，并且是合成或天然可生物降解的粘合剂或其组合。 位于可生物降解的活性载体上的活性成分包括生物相容性藻类人造皮肤层，包括无菌水和至少重量百分之六十的重组海藻。 层状海藻可用于其所需的硫酸多糖基硫酸盐含量。 活性成分通过首先干燥原料，将原料转化为粉末，然后用灭菌水和其它可能的活性物质和/或惰性物质来重构粉末来制备。