公开(公告)号：US20140275980A1

公开(公告)日：2014-09-18

申请号：US14208322

申请日：2014-03-13

申请人： MRI Interventions, Inc.

发明人： Jesse Flores

IPC分类号： G01R33/28

CPC分类号： G01R33/287 ,  A61B18/1492 ,  A61B34/20 ,  A61B2018/00351 ,  A61B2090/374

摘要： An MRI-compatible tip assembly for an MRI-compatible medical device includes a first tubular member, a second tubular member, a ring electrode, and a tip electrode. The tip electrode proximal end is secured to the first tubular member distal end. The second tubular member distal end is inserted through the ring electrode and is secured to the first tubular member proximal end. When assembled, the tip assembly is a substantially rigid structure. Each tubular member has a recessed portion for a tracking coil.

摘要翻译： 用于MRI兼容的医疗装置的MRI兼容的尖端组件包括第一管状构件，第二管状构件，环形电极和尖端电极。 尖端电极近端被固定到第一管状构件远端。 第二管状构件远端通过环形电极插入并固定到第一管状构件近端。 当组装时，尖端组件是基本刚性的结构。 每个管状构件具有用于跟踪线圈的凹部。

公开(公告)号：US20140266207A1

公开(公告)日：2014-09-18

申请号：US13799588

申请日：2013-03-13

申请人： MRI INTERVENTIONS, INC.

发明人： Parag Karmarkar ,  Rajesh Pandey

IPC分类号： G01R33/34

CPC分类号： G01R33/287 ,  A61B18/1492 ,  A61B2017/00039 ,  A61B2018/00773 ,  A61B2018/00815 ,  A61B2034/2051

摘要： An elongate electrical lead assembly that reduces localized heating due to MR scanner-induced currents includes a first elongate electrical lead having a series of alternating single layer coil sections and multi-layer coil sections, a second elongate electrical lead having a series of alternating single layer coil sections and multi-layer coil sections, and a third elongate electrical lead having a coiled section that coaxially surrounds the first and second electrical leads. Each multi-layer coil section of the second electrical lead is coiled around a respective single layer coil section of the first electrical lead, and each single layer coil section of the second electrical lead is coiled around a respective multi-layer coil section of the first electrical lead.

摘要翻译： 由MR扫描器感应的电流减少局部加热的细长电引线组件包括具有一系列交替的单层线圈部分和多层线圈部分的第一细长电引线，具有一系列交替单层 线圈段和多层线圈段，以及具有同轴地围绕第一和第二电引线的螺旋段的第三细长电引线。 第二电引线的每个多层线圈部分围绕第一电引线的相应单层线圈部分卷绕，并且第二电引线的每个单层线圈部分围绕第一电引线的相应多层线圈部分卷绕 电铅。

公开(公告)号：US08825133B2

公开(公告)日：2014-09-02

申请号：US13749351

申请日：2013-01-24

申请人： MRI Interventions, Inc.

发明人： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores ,  Parag V. Karmarkar ,  Rajesh Pandey

IPC分类号： A61B5/05 ,  A61B5/00 ,  A61B5/06 ,  A61B18/18 ,  A61B5/053 ,  G01R33/28 ,  A61M5/00 ,  A61B5/042 ,  A61B5/055 ,  A61B18/02 ,  A61M25/06 ,  A61B19/00 ,  A61M25/00 ,  A61M29/00 ,  A61M25/01 ,  A61M25/09

CPC分类号： A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

摘要： An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.

摘要翻译： 减少由于MR扫描器感应电流引起的局部加热的MRI兼容导管包括具有远端部分和相对近端部分的细长柔性轴。 手柄附接到近端部分并且包括被配置为与MRI扫描仪电连通的电连接器接口。 一个或多个RF跟踪线圈定位在轴的远端部分附近。 每个RF跟踪线圈包括在RF跟踪线圈和电连接器接口之间延伸的导电引线，例如同轴电缆，并将RF跟踪线圈电连接到MRI扫描器。 在本发明的一些实施例中，导电引线具有足以限定MRI扫描器的工作频率的四分之一波长的奇次谐波/倍数的长度，和/或包括一系列预先形成的前后段 它的长度。

公开(公告)号：US08649842B2

公开(公告)日：2014-02-11

申请号：US13741009

申请日：2013-01-14

申请人： Boston Scientific Neuromodulation Corporation ,  MRI Interventions, Inc.

发明人： Ergin Atalar ,  Onur Ferhanoglu

IPC分类号： A61B5/04

CPC分类号： A61N1/08 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718

摘要： A lead for an electronic device which resists the induction of a current from an electromagnetic field external to said lead includes one or more pairs of adjacent segments of electrical wire, each of the pairs including a first segment of electrical wire and a second segment of electrical wire. The lead also includes one or more shielded RF chokes, wherein each of the shielded RF chokes is provided between the first segment of electrical wire and the second segment of electrical wire of a respective one of the one or more pairs of adjacent segments. Also, an implantable device that includes a generator for generating one or more electrical pulse and a lead as described for delivering the pulses to tissue within a patient's body. A method for making the described implantable device is also provided.

摘要翻译： 用于抵抗从所述引线外部的电磁场感应电流的电子装置的引线包括一对或多对相邻的电线段，每对电极包括电线的第一段和电线的第二段 线。 引线还包括一个或多个屏蔽RF扼流圈，其中屏蔽RF扼流圈中的每一个被设置在电线的第一段和一对或多对相邻段之间相应的一对的电线的第二段之间。 而且，一种可植入装置，其包括用于产生一个或多个电脉冲的发生器和如所描述的用于将脉冲传送到患者体内的组织的引线。 还提供了制造所述可植入装置的方法。

公开(公告)号：US20140024909A1

公开(公告)日：2014-01-23

申请号：US13984437

申请日：2012-02-24

申请人： Kamal Vij ,  Parag V. Karmarkar ,  Rajesh Pandey ,  Peter Piferi

发明人： Kamal Vij ,  Parag V. Karmarkar ,  Rajesh Pandey ,  Peter Piferi

IPC分类号： A61M25/01 ,  A61B5/00 ,  A61B18/18 ,  A61M5/00 ,  A61B5/04 ,  A61B18/14

CPC分类号： A61B5/04 ,  A61B5/055 ,  A61B5/062 ,  A61B5/4836 ,  A61B5/6852 ,  A61B18/02 ,  A61B18/06 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/24 ,  A61B2018/00011 ,  A61B2018/1861 ,  A61B2034/2051 ,  A61B2090/374 ,  A61B2090/3954 ,  A61B2218/002 ,  A61M5/00 ,  A61M25/0127 ,  A61N7/022

摘要： An MRI-compatible catheter reduces localized heating due to MR scanner-induced currents and includes a shaft having opposite distal and proximal end portions. One or more RF tracking coils are positioned adjacent the distal end portion and each includes a conductive lead that electrically connects the RF tracking coil to an MRI scanner. Each lead includes a series of back and forth segments along its length. The catheter includes one or more sensing electrodes at the shaft distal end portion, each electrically connected to a resistor having high impedance. A sheath surrounds a portion of the elongated shaft and includes at least one RF shield coaxially disposed therewithin. Each RF shield includes elongated inner and outer conductors and an elongated dielectric layer of MRI compatible material sandwiched between the inner and outer conductors. The inner and outer conductors are electrically connected at one end and electrically isolated at an opposite end.

摘要翻译： MRI兼容导管由于MR扫描器感应电流而减少了局部加热，并且包括具有相对的远端和近端部分的轴。 一个或多个RF跟踪线圈定位成与远端部分相邻，并且每个包括将RF跟踪线圈电连接到MRI扫描器的导电引线。 每个引线包括沿其长度的一系列前后段。 导管包括在轴远端部分处的一个或多个感测电极，每个感测电极电连接到具有高阻抗的电阻器。 护套围绕细长轴的一部分并且包括同轴地设置在其中的至少一个RF护罩。 每个RF屏蔽包括细长的内部和外部导体以及夹在内部和外部导体之间的兼容MRI的材料的细长电介质层。 内导体和外导体在一端电连接并在相对端电隔离。

公开(公告)号：US20130178924A1

公开(公告)日：2013-07-11

申请号：US13741009

申请日：2013-01-14

申请人： Boston Scientific Neuromodulation Corporation ,  MRI Interventions, Inc

发明人： Ergin Atalar ,  Onur Ferhanoglu

IPC分类号： A61N1/08

CPC分类号： A61N1/08 ,  A61N1/05 ,  A61N1/086 ,  A61N1/3718

摘要： A lead for an electronic device which resists the induction of a current from an electromagnetic field external to said lead includes one or more pairs of adjacent segments of electrical wire, each of the pairs including a first segment of electrical wire and a second segment of electrical wire. The lead also includes one or more shielded RF chokes, wherein each of the shielded RF chokes is provided between the first segment of electrical wire and the second segment of electrical wire of a respective one of the one or more pairs of adjacent segments. Also, an implantable device that includes a generator for generating one or more electrical pulse and a lead as described for delivering the pulses to tissue within a patient's body. A method for making the described implantable device is also provided.

公开(公告)号：US08460328B2

公开(公告)日：2013-06-11

申请号：US13421344

申请日：2012-03-15

申请人： Peter Piferi

发明人： Peter Piferi

IPC分类号： A61B17/14

CPC分类号： A61B17/16 ,  A61B17/1655 ,  A61B17/1695 ,  A61B17/17 ,  A61B90/39 ,  A61B2017/00911 ,  A61B2090/3916 ,  A61B2090/3987

摘要： A surgical marking tool for marking a location on a patient includes a cutting head and a handle. The cutting head includes a screw thread. The handle is coupled to the cutting head to rotate the cutting head. The screw thread is configured to progressively embed in the patient to mark the location when the cutting head is placed in contact with the patient and rotated with respect to the patient using the handle.

摘要翻译： 用于标记患者位置的外科标记工具包括切割头和手柄。 切割头包括螺纹。 手柄连接到切割头以旋转切割头。 螺纹构造成逐渐嵌入患者体内，以便当切割头与患者接触并且使用手柄相对于患者旋转时标记位置。

公开(公告)号：US20130116543A1

公开(公告)日：2013-05-09

申请号：US13723612

申请日：2012-12-21

申请人： MRI Interventions, Inc.

发明人： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij

IPC分类号： A61B5/06 ,  A61M29/00

CPC分类号： A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

摘要： An MRI-guided medical device includes an elongated sheath, an elongated dilator, and an elongated needle. The sheath has a distal end, an opposite proximal end, and a central lumen extending between the proximal and distal ends. The sheath comprises MRI-compatible material and includes a tracking member located adjacent to the sheath distal end that is visible in an MRI image. The dilator comprises MRI-compatible material and is movably disposed within the sheath lumen. A distal end of the dilator is configured to extend outwardly from the sheath distal end and dilator includes at least one tracking member that is visible in an MRI image. The needle is movably disposed within the dilator lumen and is movable between stored and operative positions relative to the dilator. An RF shield may be coaxially disposed within the elongated sheath so as to surround a portion of the sheath central lumen.

摘要翻译： MRI引导的医疗装置包括细长护套，细长扩张器和细长针头。 鞘具有远端，相对的近端和在近端和远端之间延伸的中心腔。 护套包括与MRI相容的材料，并且包括位于MRI图像中可见的护套远端附近的跟踪构件。 扩张器包括与MRI相容的材料，并且可移动地设置在鞘腔内。 扩张器的远端构造成从护套远端向外延伸，并且扩张器包括在MRI图像中可见的至少一个跟踪构件。 针可移动地设置在扩张器腔内，并且可在相对于扩张器的存储和操作位置之间移动。 RF屏蔽件可以同轴地设置在细长护套内，以便围绕护套中心腔的一部分。

公开(公告)号：US20130102883A1

公开(公告)日：2013-04-25

申请号：US13717226

申请日：2012-12-17

申请人： MRI Interventions, Inc.

发明人： Peter Piferi ,  Kimble L. Jenkins ,  David John Sayler

IPC分类号： A61B5/06 ,  A61B18/00 ,  A61B5/00 ,  A61N1/05 ,  A61B5/055 ,  A61B19/00

CPC分类号： A61B5/062 ,  A61B5/004 ,  A61B5/0042 ,  A61B5/0044 ,  A61B5/055 ,  A61B5/0555 ,  A61B5/4836 ,  A61B5/4839 ,  A61B18/00 ,  A61B34/10 ,  A61B34/25 ,  A61B34/74 ,  A61B90/11 ,  A61B90/14 ,  A61B90/361 ,  A61B90/37 ,  A61B90/50 ,  A61B2017/00212 ,  A61B2017/00477 ,  A61B2017/00911 ,  A61B2017/3407 ,  A61B2017/3409 ,  A61B2034/101 ,  A61B2034/107 ,  A61B2034/252 ,  A61B2034/256 ,  A61B2090/103 ,  A61B2090/306 ,  A61B2090/3614 ,  A61B2090/373 ,  A61B2090/374 ,  A61B2090/3933 ,  A61B2090/3937 ,  A61B2090/395 ,  A61B2090/3954 ,  A61B2090/3983 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/36014 ,  A61N1/372 ,  G01R33/286 ,  G01R33/287 ,  G01R33/3415

摘要： An MRI-guided interventional system includes a trajectory guide frame for guiding an interventional device with respect to a patient in an MRI-guided procedure and including a base, a platform, a targeting cannula, and a stabilizer mechanism. The platform is mounted on the base and includes a support table and a moving plate that is translatable relative to the support table and the base along a translational axis. The targeting cannula is mounted on the moving plate for movement therewith and includes an elongate guide bore defining a trajectory axis. The stabilizer mechanism is operable to selectively control movement between the support table and the moving plate to stabilize a position of the targeting cannula with respect to the base. The frame is operable to translate the moving plate along the translational axis relative to the base to position the trajectory axis. The translational axis is transverse to the trajectory axis.

摘要翻译： MRI引导的介入系统包括用于在MRI引导过程中引导介入装置相对于患者的轨迹引导框架，并且包括基座，平台，靶向插管和稳定器机构。 平台安装在基座上并且包括支撑台和移动板，其可相对于支撑台和基座沿平移轴线平移。 靶向套管安装在移动板上以与其一起运动并且包括限定轨迹轴线的细长导向孔。 稳定器机构可操作以选择性地控制支撑台和移动板之间的运动，以使靶向套管相对于基座的位置稳定。 该框架可操作以使移动板沿相对于基座的平移轴平移以定位轨迹轴。 平移轴线横向于轨迹轴线。

公开(公告)号：US08396532B2

公开(公告)日：2013-03-12

申请号：US12816757

申请日：2010-06-16

申请人： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij

发明人： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij

IPC分类号： A61B5/05

CPC分类号： A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

摘要： An MRI-guided medical device includes an elongated sheath, an elongated dilator, and an elongated needle. The sheath has a distal end, an opposite proximal end, and a central lumen extending between the proximal and distal ends. The sheath comprises MRI-compatible material and includes a tracking member located adjacent to the sheath distal end that is visible in an MRI image. The dilator comprises MRI-compatible material and is movably disposed within the sheath lumen. A distal end of the dilator is configured to extend outwardly from the sheath distal end and dilator includes at least one tracking member that is visible in an MRI image. The needle is movably disposed within the dilator lumen and is movable between stored and operative positions relative to the dilator. An RF shield may be coaxially disposed within the elongated sheath so as to surround a portion of the sheath central lumen.

摘要翻译： MRI引导的医疗装置包括细长护套，细长扩张器和细长针头。 鞘具有远端，相对的近端和在近端和远端之间延伸的中心腔。 护套包括与MRI相容的材料，并且包括位于MRI图像中可见的护套远端附近的跟踪构件。 扩张器包括与MRI相容的材料，并且可移动地设置在鞘腔内。 扩张器的远端构造成从护套远端向外延伸，并且扩张器包括在MRI图像中可见的至少一个跟踪构件。 针可移动地设置在扩张器腔内，并且可在相对于扩张器的存储和操作位置之间移动。 RF屏蔽件可以同轴地设置在细长护套内，以便围绕护套中心腔的一部分。