公开(公告)号：US20140378658A1

公开(公告)日：2014-12-25

申请号：US14372913

申请日：2013-01-21

申请人： Instituto Superiore di Sanita ,  Alma Mater Studiorum - Universita di Bologna

发明人： Carla Fiorentini ,  Stefano Loizzo ,  Fiorella Malchiodi-Albedi ,  Sara Travaglione ,  Roberto Rimondini ,  Gabriele Campana

IPC分类号： A61K38/16

CPC分类号： A61K38/164

摘要： Cytotoxic necrotising factor 1 (CNF1) treats dysfunctional astrocytes and is useful to treat conditions associated with astrogliosis and/or neuroinflammation.

摘要翻译： 细胞毒性坏死因子1（CNF1）治疗功能失调的星形胶质细胞，可用于治疗与星形胶质细胞增生和/或神经炎症相关的病症。

公开(公告)号：US20140225094A1

公开(公告)日：2014-08-14

申请号：US14236551

申请日：2011-08-02

申请人： Beatrice Fraboni ,  Alessandro Fraleoni Morgera

发明人： Beatrice Fraboni ,  Alessandro Fraleoni Morgera

IPC分类号： H01L51/44 ,  H01L51/00

CPC分类号： H01L51/441 ,  G01T1/24 ,  H01L51/0003 ,  H01L51/0067

摘要： The present invention relates to organic semiconductors to be used as intrinsic, direct detectors for ionizing radiations, such as X and gamma rays, neutrons, and charged particles (alpha rays, electrons, positrons, and the like), and to a method for manufacturing such intrinsic, direct detectors for ionizing radiations. The invention further relates to instruments or complex devices provided with a detector based on, or somehow incorporating, the above detectors.

摘要翻译： 本发明涉及用作电离辐射的固有的直接检测器，例如X和γ射线，中子和带电粒子（α射线，电子，正电子等）的有机半导体，以及制造方法 这种内在的，用于电离辐射的直接检测器。 本发明还涉及具有基于或以某种方式结合上述检测器的检测器的仪器或复合器件。

公开(公告)号：US20140093731A1

公开(公告)日：2014-04-03

申请号：US14003111

申请日：2012-03-06

申请人： Annalisa Bonfiglio ,  Beatrice Fraboni ,  Giorgio Mattana

发明人： Annalisa Bonfiglio ,  Beatrice Fraboni ,  Giorgio Mattana

IPC分类号： H01B1/22 ,  H01L51/05 ,  H01B13/00

CPC分类号： H01B1/22 ,  H01B1/00 ,  H01B13/0036 ,  H01L51/0558 ,  Y10T428/2944 ,  Y10T428/2949

摘要： The invention relates to a conductive fiber material comprising a base fiber material (1) including a textile fiber, a plurality of nanoparticles (20) deposited on an external surface (10) of said base fiber material, said nanoparticles including one or more metals or metal oxides and a conductive polymer layer deposited on said external surface including nanoparticles.

摘要翻译： 本发明涉及一种导电纤维材料，其包括基材纤维材料（1），其包括纺织纤维，沉积在所述基础纤维材料的外表面（10）上的多个纳米颗粒（20），所述纳米颗粒包括一种或多种金属或 金属氧化物和沉积在包括纳米颗粒的所述外表面上的导电聚合物层。

公开(公告)号：US20130123546A1

公开(公告)日：2013-05-16

申请号：US13703618

申请日：2011-06-10

申请人： Giovanni Camer Roda ,  Vincenzo Augugliaro ,  Vittorio Loddo ,  Giovanni Palmisano ,  Leonardo Palmisano

发明人： Giovanni Camer Roda ,  Vincenzo Augugliaro ,  Vittorio Loddo ,  Giovanni Palmisano ,  Leonardo Palmisano

IPC分类号： C07C45/27 ,  C07C45/29

CPC分类号： C07C45/27 ,  C07C45/29 ,  C07C45/36 ,  C07C45/38 ,  C07C45/78 ,  C07C47/54 ,  C07C47/565 ,  C07C47/228 ,  C07C47/542 ,  C07C47/55 ,  C07C47/575

摘要： A process for the preparation of an aromatic aldehyde by means of the oxidation of the corresponding starting compound in aqueous medium, and separation of said aldehyde from said medium by pervaporation is disclosed together a plant for its carrying out. Advantageously, the process of the present invention allows control of oxidation reaction and recovery of the product with high selectivity and purity. Among others, benzaldehyde, anisaldehyde and vanillin can advantageously be prepared by this process.

摘要翻译： 通过在水性介质中氧化相应起始化合物并通过全蒸发从所述介质中分离醛的方法公开在一起用于其进行的设备。 有利地，本发明的方法允许以高选择性和纯度控制氧化反应和回收产物。 其中，苯甲醛，茴香醛和香草醛可有利地通过该方法制备。

公开(公告)号：US08410924B2

公开(公告)日：2013-04-02

申请号：US12598889

申请日：2008-05-02

申请人： Alessandra Costanzo ,  Andrea Benedetti ,  Vittorio Rizzoli

发明人： Alessandra Costanzo ,  Andrea Benedetti ,  Vittorio Rizzoli

IPC分类号： G08B1/08 ,  G01B7/16 ,  G01F25/00 ,  G01L1/00

CPC分类号： G01M5/0091 ,  G01M5/0041

摘要： A low-cost and non-invasive method for remote monitoring deformations of a structure (2), which method envisages to couple at least two RFID tags (3) to the structure (2) in its respective points (10a, 10b, 10a-10c), to interrogate at radio frequency the RFID tags (3) so that a resultant electromagnetic field is produced at a certain distance (DINF) from the structure (2), the resultant electromagnetic field ensuing from a combination of the electromagnetic fields produced individually by each RFID tags (3) in response to the interrogation, to measure the resultant electromagnetic field at such a distance (DINF) from the structure (2) for obtaining measurements of the resultant electromagnetic field, and to determine the deformations of the structure (2) as a function of the measurements of the resultant electromagnetic field.

摘要翻译： 一种用于远程监测结构（2）变形的低成本和非侵入性方法，该方法设想将其至少两个RFID标签（3）耦合到其各自点（10a，10b，10a- 10c），以无线电频率询问RFID标签（3），使得从结构（2）产生一定距离（DINF）的合成电磁场，从单独产生的电磁场的组合产生的所得到的电磁场 通过每个RFID标签（3）响应于询问，以从结构（2）测量所得到的电磁场（DINF），以获得所得到的电磁场的测量值，并确定结构的变形（ 2）作为所得电磁场的测量的函数。

公开(公告)号：US20110275729A1

公开(公告)日：2011-11-10

申请号：US13122686

申请日：2008-10-15

申请人： Mariastella Scandola ,  Laura Mazzocchetti ,  Maria Letizia Focarete ,  Michal Kawalec ,  Piotr Kurcok ,  Grazyna Adamus ,  Marek Kowalczuk

发明人： Mariastella Scandola ,  Laura Mazzocchetti ,  Maria Letizia Focarete ,  Michal Kawalec ,  Piotr Kurcok ,  Grazyna Adamus ,  Marek Kowalczuk

IPC分类号： C08G63/06 ,  C07D301/02 ,  C08G63/91 ,  C07C69/675 ,  C08J9/08

CPC分类号： C08G63/912 ,  C08G63/06

摘要： The present invention relates to a process for producing polyhydroxyalkanoate oligomers and/or polymers of reduced molecular weight, which comprises reacting at least one polyhydroxyalkanoate (PHA) with at least one carbonate salt at a temperature of from 50° C. to 300° C., preferably from 120° C. to 200° C. The above reaction allows a controlled degradation of the PHA chains which yields oligomers and/or polymers having a controlled molecular weight, which can be modulated in view of the specific application for which the oligomers and/or polymers are intended. Moreover, during the reaction carbon dioxide evolves which produces a foamed material which can be easily processed on an industrial scale. Additionally, the above oligomers and/or polymers, having an end-group bearing a double bond C═C, particularly a crotonate end-group for PHB, can be subjected to subsequent modifications to obtain a wide variety of functional end-groups, for instance carboxyl, carboxylate, hydroxyl, dihydroxyl, oxirane ring, halogen atom. Moreover, the low molecular weight PHAs may be used in the area of controlled delivery systems in agro-chemistry, in the cosmetic industry, in medicine in the form of nano- or microspheres, in household products and in coating systems.

摘要翻译： 本发明涉及一种生产低分子量聚羟基链烷酸酯低聚物和/或聚合物的方法，该方法包括使至少一种聚羟基链烷酸酯（PHA）与至少一种碳酸盐在50℃至300℃的温度下反应。 ，优选为120℃至200℃。上述反应允许PHA链的受控降解，其产生具有受控分子量的低聚物和/或聚合物，其可以根据具体应用进行调节，其中低聚物 和/或聚合物。 此外，在反应过程中，二氧化碳逸出，产生可以以工业规模容易地加工的泡沫材料。 此外，具有带双键C = C的端基，特别是PHB的巴豆酸酯端基的上述低聚物和/或聚合物可以进行随后的修饰以获得多种功能性端基，对于 羧基，羧基，羟基，二羟基，环氧乙烷环，卤素原子。 此外，低分子量PHA可用于农业化学，化妆品工业中的控制递送系统，以纳米或微球形式在家用产品和涂料体系中的医药领域。

公开(公告)号：US07589219B2

公开(公告)日：2009-09-15

申请号：US10510833

申请日：2003-04-11

申请人： Vincenza Andrisano ,  Manuela Bartolini ,  Maria Laura Bolognesi ,  Andrea Cavalli ,  Carlo Melchiorre ,  Maurizio Recanatini

发明人： Vincenza Andrisano ,  Manuela Bartolini ,  Maria Laura Bolognesi ,  Andrea Cavalli ,  Carlo Melchiorre ,  Maurizio Recanatini

IPC分类号： C07D307/02

CPC分类号： C07D307/52 ,  C07C225/28

摘要： 2,5-bis-diamine-[1,4]benzoquinonic derivatives, having a general formula (I) have proved useful for the treatment of Alzheimer's disease; a method for preparing them and intermediates used in said method are also described.

摘要翻译： 具有通式（I）的2,5-双 - 二胺 - [1,4]苯醌衍生物已被证明可用于治疗阿尔茨海默病; 还描述了用于制备它们的方法和用于所述方法的中间体。

公开(公告)号：US20080306604A1

公开(公告)日：2008-12-11

申请号：US12159474

申请日：2006-12-28

申请人： Vincenzo Parenti Castelli

发明人： Vincenzo Parenti Castelli

IPC分类号： A61F2/38

CPC分类号： A61F2/38 ,  A61F2/08 ,  A61F2/3804 ,  A61F2/40 ,  A61F2/4202 ,  A61F2002/30639 ,  A61F2002/30934 ,  A61F2002/30945

摘要： An orthopaedic device (1) for the mobile connection of a first and a second bony segment (4, 5) of an organic device for cooperating with or substituting a natural articulation comprising a first working surface (9) related to the first cooperating segment (4) with a second working surface (10) related to the second bony segment (5) in order to constrain (guide) the relative motion between the said bony segments (4, 5); the first and the second working surface (9, 10) are respectively practically shaped as the axodes of the relative motion of a first and a second link of a linkage practically equivalent to the natural articulation; in particular the first and the second link are corresponding, in the linkage, to the first and the second bony segment (4, 5).

摘要翻译： 一种用于与有机装置的第一和第二骨段（4,5）的移动连接的矫形装置（1），用于与自然关节相配合或替代自然关节，包括与第一协作部分相关的第一工作表面（9） 4），其具有与所述第二骨段（5）相关的第二工作表面（10），以限制（引导）所述骨段（4,5）之间的相对运动; 第一和第二工作表面（9,10）分别实际上成形为实际上等同于自然关节的连杆的第一和第二连杆的相对运动的轴向; 特别地，第一和第二连杆在连接时对应于第一和第二骨段（4,5）。

公开(公告)号：US11894052B2

公开(公告)日：2024-02-06

申请号：US17718908

申请日：2022-04-12

申请人： STMicroelectronics S.r.l. ,  Alma Mater Studiorum-Universita' Di Bologna

发明人： Marco Pasotti ,  Marcella Carissimi ,  Alessio Antolini ,  Eleonora Franchi Scarselli ,  Antonio Gnudi ,  Andrea Lico ,  Paolo Romele

IPC分类号： G11C16/06 ,  G11C13/00

CPC分类号： G11C13/0061 ,  G11C13/0004 ,  G11C13/0026 ,  G11C13/0038

摘要： An in-memory computation (IMC) circuit includes a memory array formed by memory cells arranged in row-by-column matrix. Computational weights for an IMC operation are stored in the memory cells. Each column includes a bit line connected to the memory cells. A biasing circuit is connected between each bit line and a corresponding column output. A column combining circuit combines and integrates analog signals at the column outputs of the biasing circuits. Each biasing circuit operates to apply a fixed reference voltage level to its bit line. Each biasing circuit further includes a switching circuit that is controlled to turn on for a time duration controlled by asps comparison of a coefficient data signal to a ramp signal to generate the analog signal dependent on the computational weight. The ramp signal is generated using a reference current derived from a reference memory cell.

公开(公告)号：US20230318532A1

公开(公告)日：2023-10-05

申请号：US18191485

申请日：2023-03-28

申请人： STMicroelectronics S.r.l. ,  Alma Mater Studiorum - Universita' Di Bologna

发明人： Alessia Maria Elgani ,  Matteo D'Addato ,  Luca Perilli ,  Eleonora Franchi Scarselli ,  Antonio Gnudi ,  Roberto Antonio Canegallo ,  Giulio Ricotti

IPC分类号： H03F1/02 ,  H03F1/32

CPC分类号： H03F1/0222 ,  H03F1/32 ,  H03F2200/102

摘要： In accordance with an embodiment, an envelope detector includes a first transistor having a first current conduction terminal coupled to a first connection node; a second current conduction terminal coupled to an intermediate node; and a control terminal coupled the signal input node and to a biasing node; a second transistor having a first current conduction terminal coupled to the intermediate node; a second current conduction terminal coupled to a second connection node; and a control terminal coupled to the biasing node; and a first temperature compensating transistor that is diode-connected and coupled between a compensation output node and the biasing node. The second connection node is coupled to the compensation output node and the first connection node is coupled to a detector output.