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    Application using non-covalent bond between a cucurbituril derivative and a ligand
    46.
    发明授权
    Application using non-covalent bond between a cucurbituril derivative and a ligand 有权
    在葫芦巴衍生物和配体之间使用非共价键的应用

    公开(公告)号：US07479254B2

    公开(公告)日：2009-01-20

    申请号：US11407143

    申请日：2006-04-20

    申请人： Kimoon Kim ,  Kangkyun Baek ,  Jeeyeon Kim ,  Iiha Hwang ,  Young Ho Ko ,  Narayanan Selvapalam ,  Erumaipatty R. Nagarajan ,  Kyeng Min Park

    发明人： Kimoon Kim ,  Kangkyun Baek ,  Jeeyeon Kim ,  Iiha Hwang ,  Young Ho Ko ,  Narayanan Selvapalam ,  Erumaipatty R. Nagarajan ,  Kyeng Min Park

    IPC分类号： B01L3/00 ,  A61K9/36 ,  A61K45/00 ,  C12Q1/68 ,  G01N15/06 ,  G01N33/53

    CPC分类号： C07D487/22 ,  B01D15/3804 ,  B01J31/0249 ,  B01J31/0251 ,  B01J31/1658 ,  B82Y5/00 ,  B82Y15/00 ,  C07K1/22

    摘要： Provided are a kit including a first component that is a compound of formula (1) below bound to a first material and a second component that is a ligand bound to a second material, wherein each of the first and second materials is independently selected from the group consisting of a solid phase, a biomolecule, an antioxidant, a chemical therapeutic agent, an anti-histaminic agent, a cucurbituril dendrimer, a cyclodextrin derivative, a crown ether derivative, a calixarene derivative, a cyclophane derivative, a cyclic peptide derivative, a metallic ion, a chromophore, a fluorescent material, a phosphor, a radioactive material, and a catalyst; and the ligand can non-covalently bind to the compound of formula (1); a method of separating and purifying a material bound to a ligand using the compound of formula (1) bound to a solid phase; a method of separating and purifying the compound of formula (1) or a material bound to the compound using a ligand bound to a solid phase; a sensor chip including a compound of formula (1) bound to a first material and a ligand bound to a second material; and a solid-catalyst complex including the compound of formula (1) bound to a first material and a ligand bound to a second material.

    摘要翻译： 本发明提供了一种试剂盒，其包含第一组分，其为下式结合于第一材料的式（1）化合物，第二组分为与第二材料结合的配体，其中第一和第二材料中的每一种独立地选自 由固相，生物分子，抗氧化剂，化学治疗剂，抗组胺药，葫芦巴树枝状大分子，环糊精衍生物，冠醚衍生物，杯芳烃衍生物，环戊烷衍生物，环肽衍生物， 金属离子，发色团，荧光材料，荧光体，放射性材料和催化剂; 并且配体可以非共价结合式（1）的化合物; 使用与固相结合的式（1）化合物分离和纯化与配体结合的材料的方法; 使用与固相结合的配体分离和纯化式（1）化合物或与化合物结合的物质的方法; 包含与第一材料结合的式（1）化合物和与第二材料结合的配体的传感器芯片; 和包含与第一材料结合的式（1）化合物和与第二材料结合的配体的固体催化剂络合物。

    Preparations for the application of anti-inflammatory agents
    47.
    发明授权
    Preparations for the application of anti-inflammatory agents 有权
    抗炎剂的应用准备

    公开(公告)号：US07468194B1

    公开(公告)日：2008-12-23

    申请号：US09979852

    申请日：2000-05-25

    申请人： Wolfgang Fleischer ,  Karen Reimer

    发明人： Wolfgang Fleischer ,  Karen Reimer

    IPC分类号： A61K9/127 ,  A61K9/36 ,  A61K31/74 ,  A61K31/79 ,  A61K25/00

    CPC分类号： A61K9/127

    摘要： Disclosed in certain embodiments is a method of treating infections of an interior part of the human or animal body, comprising administering to said interior body part, a pharmaceutical preparation comprising a particulate carrier and an effective amount of an agent selected from the group consisting of an antiseptic agent, a wound-healing promoting agent and a combination thereof, to treat an infection at said interior body part.

    摘要翻译： 在某些实施方案中公开的是治疗人或动物体内部的感染的方法，包括对所述内部身体部位施用包含颗粒状载体的药物制剂和有效量的选自以下的药剂： 防腐剂，伤口愈合促进剂及其组合，以治疗所述内部身体部位的感染。

    COMPRESSIBLE SOLID PARTICLES, PROCEDURES FOR THE OBTENTION THEREOF AND PROCEDURES FOR THE USE OF SAID PARTICLES IN BODY-CLEANSING TABLETS
    50.
    发明申请
    COMPRESSIBLE SOLID PARTICLES, PROCEDURES FOR THE OBTENTION THEREOF AND PROCEDURES FOR THE USE OF SAID PARTICLES IN BODY-CLEANSING TABLETS 审中-公开
    可压缩固体颗粒，其阻止的程序和使用颗粒清洁片中的颗粒的程序

    公开(公告)号：US20080152711A1

    公开(公告)日：2008-06-26

    申请号：US11961556

    申请日：2007-12-20

    申请人： Jose Alejandro Mumoli ,  Ruben Antonio Makuc

    发明人： Jose Alejandro Mumoli ,  Ruben Antonio Makuc

    IPC分类号： A61K9/20 ,  A61K9/14 ,  A61K47/18 ,  A61K47/06 ,  A61K9/36 ,  A61K47/38 ,  A61K47/04

    CPC分类号： A61K8/731 ,  A61K8/0216 ,  A61K8/11 ,  A61K8/19 ,  A61K8/24 ,  A61K8/25 ,  A61K8/26 ,  A61K8/34 ,  A61K8/345 ,  A61K8/347 ,  A61K8/42 ,  A61K8/442 ,  A61K8/60 ,  A61K8/732 ,  A61K8/922 ,  A61K9/1611 ,  A61K9/1617 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2054 ,  A61K2800/5422 ,  A61K2800/5424 ,  A61Q5/02 ,  A61Q19/10

    摘要： Compressible solid tablets comprising from 20 to 38 wt % of an oily or viscous liquid, from 50 to 70 wt % of a cellulose polymer and from 2 to 15 wt % of an hydrophobic coating compound, wherein said particles size is 180 microns or less. For example, the oily or viscous liquid may consist of plant oils or surfactants such as cocamide DEA, cocoamide propyl betaine and or mixtures thereof. The cellulose polymer may be carboxy methyl cellulose, microcrystalline cellulose or mixtures thereof. The coating hydrophobic composition may be silicon dioxide, calcium orthophosphate, magnesium carbonate, aluminum oxide. Compressible solid particles are also disclosed which comprise from 50 to 70 wt % of a crystalline alcohol, from 25 to 45% of a cellulose polymer and from 5 to 18 wt % of a coating hydrophobic compound. For example, the crystalline alcohol may be a polyol such as xylitol, isomaltose, sorbitol, maltitol, starch hydrolysate; a terpene such as thymol, carvacrol or menthol. Particles are used in the manufacturing of tablets for personal hygiene in a quantity comprised from 1 to 16 wt % on the basis of the whole tablet.

    摘要翻译： 包含20至38重量％的油状或粘稠液体，50至70重量％的纤维素聚合物和2至15重量％的疏水涂层化合物的可压缩固体片剂，其中所述颗粒尺寸为180微米或更小。 例如，油性或粘稠液体可以由植物油或表面活性剂组成，例如椰油酰胺DEA，椰油酰胺丙基甜菜碱及其混合物。 纤维素聚合物可以是羧甲基纤维素，微晶纤维素或其混合物。 涂层疏水组合物可以是二氧化硅，正磷酸钙，碳酸镁，氧化铝。 还公开了可压缩固体颗粒，其包含50至70重量％的结晶醇，25至45重量％的纤维素聚合物和5至18重量％的涂覆疏水性化合物。 例如，结晶醇可以是多元醇，例如木糖醇，异麦芽糖，山梨糖醇，麦芽糖醇，淀粉水解产物; 萜烯，如百里香酚，香芹酚或薄荷醇。 基于整个片剂，颗粒用于制造个人卫生用片剂，其量为1至16重量％。