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公开(公告)号：US20080166407A1
公开(公告)日：2008-07-10
申请号：US12072083
申请日：2008-02-21
IPC分类号： A61K9/24 , A61K9/36 , A61K9/20 , A61K31/341 , A61K31/192 , A61K31/60 , A61K31/19 , A61K31/4439 , A61K31/167
CPC分类号： A61K31/19 , A61K9/2031 , A61K9/2054 , A61K9/209 , A61K9/2866 , A61K31/00 , A61K31/167 , A61K31/192 , A61K31/34 , A61K31/341 , A61K31/44 , A61K31/4439 , A61K31/60 , A61K2300/00
摘要： Multifunctional, single, bilayer, and trilayer coated tablets for combination therapy are formed wherein the bioactive agents responsible for the therapeutic multifunctionality are present as a combination of a gastric acid-reducing agent, such as omeprazole and ranitidine, and at least one analgesic/anti-inflammatory agent, such as acetaminophen, naproxen sodium, ibuprofen, tolmetin, and aspirin.
摘要翻译： 形成用于联合治疗的多功能，单层，双层和三层包衣片剂，其中负责治疗多功能性的生物活性剂作为胃酸还原剂如奥美拉唑和雷尼替丁的组合存在，以及至少一种镇痛/抗 抗炎剂，如对乙酰氨基酚，萘普生钠，布洛芬，托美丁和阿司匹林。
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2.发明申请Radiation and radiochemically sterilized fiber-reinforced, composite urinogenital stents 有权辐射和放射化学灭菌的纤维增强，复合尿殖器支架公开(公告)号：US20090177286A1
公开(公告)日：2009-07-09
申请号：US12378221
申请日：2009-02-12
IPC分类号： A61F2/04
CPC分类号： A61F2/86 , A61F2/04 , A61F2/94 , A61F2210/0004 , A61F2210/0076 , A61L31/048 , A61L31/129 , A61L31/148 , A61L31/16 , A61L31/18 , A61L2300/404 , A61L2300/416 , A61M25/0108 , A61M27/008
摘要： A radiation and radiochemically sterilized, multi-component, fiber-reinforced composite, absorbable/disintegratable urinogenital stent, such as an endoureteral stent, with radiomodulated residence time in the biological site of 1 to 10 weeks depending on the high energy radiation dose used for sterilization.
摘要翻译： 辐射和放射化学消毒的多组分纤维增强复合材料，可吸收/分解的尿道内支架，如输尿管内支架，根据用于灭菌的高能量辐射剂量，在生物部位的放射性调节停留时间为1至10周 。
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3.发明授权Radiopaque iodinated and iodide-containing crystalline absorbable aliphatic polymeric materials and applications thereof 有权不透射碘的碘化物和含碘化物的可吸收的脂族聚合物材料及其应用公开(公告)号：US08808357B2
公开(公告)日：2014-08-19
申请号：US12798461
申请日：2010-04-06
IPC分类号： A61F2/06 , A61F2/00 , C08G64/02 , C08G63/682 , C09D167/04 , C08G18/73 , C08G18/46 , C09D169/00
CPC分类号： A61L31/18 , A61K47/34 , A61L27/18 , A61L27/58 , A61L29/085 , A61L29/148 , A61L29/18 , A61L31/06 , A61L31/10 , A61L31/148 , C08G18/4607 , C08G18/73 , C08G63/6822 , C08G64/0233 , C09D167/04 , C09D169/00 , Y10T428/139
摘要： Radiopaque, iodinated, absorbable polyesters, polyester urethanes, and polyether-ester-urethanes with and without inorganic iodide micro-/nanoparticles dispersed or solubilized therein, and composite inorganic iodide micro-/nanoparticles in an absorbable polyester, polyester-urethane, polyester-ester, or polyether-ester urethane matrix are employed in medical devices and therapeutic compositions.
摘要翻译： 不溶性，碘化，可吸收的聚酯，聚酯氨酯和聚醚 - 酯 - 聚氨酯，其中分散有或不溶于其中的无机碘化物微/纳米颗粒，以及可吸收聚酯中的复合无机碘化物微/纳米颗粒，聚酯 - 聚氨酯，聚酯酯 ，或聚醚 - 酯聚氨酯基质用于医疗器械和治疗组合物。
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4.发明申请公开(公告)号：US20130144264A1
公开(公告)日：2013-06-06
申请号：US13754110
申请日：2013-01-30
CPC分类号： A61K31/7036 , A01N25/34 , A61K9/0034 , A61K9/0053 , A61K31/12 , A61K31/192 , A61K31/337 , A61K31/4025 , A61K31/4164 , A61K31/4174 , A61K31/4196 , A61K31/427 , A61K31/436 , A61K31/496 , A61K31/497 , A61K31/505 , A61K31/506 , A61K31/65 , A61K47/34 , A61M25/002 , A61M25/04 , A61M25/10 , A61M31/00 , A61M31/007 , A61M2025/0024 , A61M2025/105 , B65B3/04 , B65B51/10 , B65B55/04 , B65B55/14 , B65D65/38
摘要： Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.
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5.发明申请RADIATION AND RADIOCHEMICALLY STERILIZED FIBER-REINFORCED, COMPOSITE URINOGENITAL STENTS 审中-公开辐射和无机化学灭菌纤维增强复合尿素公开(公告)号：US20120083897A1
公开(公告)日：2012-04-05
申请号：US13301894
申请日：2011-11-22
IPC分类号： A61F2/04
CPC分类号： A61F2/86 , A61F2/04 , A61F2/94 , A61F2210/0004 , A61F2210/0076 , A61L31/048 , A61L31/129 , A61L31/148 , A61L31/16 , A61L31/18 , A61L2300/404 , A61L2300/416 , A61M25/0108 , A61M27/008
摘要： A radiation and radiochemically sterilized, multi-component, fiber-reinforced composite, absorbable/disintegratable urinogenital stent, such as an endoureteral stent, with radiomodulated residence time in the biological site of 1 to 10 weeks depending on the high energy radiation dose used for sterilization.
摘要翻译： 辐射和放射化学消毒的多组分纤维增强复合材料，可吸收/分解的尿道内支架，如输尿管内支架，根据用于灭菌的高能量辐射剂量，在生物部位的放射性调节停留时间为1至10周 。
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6.发明授权Radiation and radiochemically sterilized fiber-reinforced, composite urinogenital stents 有权辐射和放射化学灭菌的纤维增强，复合尿殖器支架公开(公告)号：US08083806B2
公开(公告)日：2011-12-27
申请号：US12378221
申请日：2009-02-12
CPC分类号： A61F2/86 , A61F2/04 , A61F2/94 , A61F2210/0004 , A61F2210/0076 , A61L31/048 , A61L31/129 , A61L31/148 , A61L31/16 , A61L31/18 , A61L2300/404 , A61L2300/416 , A61M25/0108 , A61M27/008
摘要： A radiation and radiochemically sterilized, multi-component, fiber-reinforced composite, absorbable/disintegratable urinogenital stent, such as an endoureteral stent, with radiomodulated residence time in the biological site of 1 to 10 weeks depending on the high energy radiation dose used for sterilization.
摘要翻译： 辐射和放射化学消毒的多组分纤维增强复合材料，可吸收/分解的尿道内支架，如输尿管内支架，根据用于灭菌的高能量辐射剂量，在生物部位的放射性调节停留时间为1至10周 。
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7.发明申请Radiopaque iodinated and iodide-containing crystalline absorbable aliphatic polymeric materials and applications thereof 有权不透射碘的碘化物和含碘化物的可吸收的脂族聚合物材料及其应用公开(公告)号：US20110245912A1
公开(公告)日：2011-10-06
申请号：US12798461
申请日：2010-04-06
CPC分类号： A61L31/18 , A61K47/34 , A61L27/18 , A61L27/58 , A61L29/085 , A61L29/148 , A61L29/18 , A61L31/06 , A61L31/10 , A61L31/148 , C08G18/4607 , C08G18/73 , C08G63/6822 , C08G64/0233 , C09D167/04 , C09D169/00 , Y10T428/139
摘要： Radiopaque, iodinated, absorbable polyesters, polyester urethanes, and polyether-ester-urethanes with and without inorganic iodide micro-/nanoparticles dispersed or solubilized therein, and composite inorganic iodide micro-/nanoparticles in an absorbable polyester, polyester-urethane, polyester-ester, or polyether-ester urethane matrix are employed in medical devices and therapeutic compositions.
摘要翻译： 不溶性，碘化，可吸收的聚酯，聚酯氨酯和聚醚 - 酯 - 聚氨酯，其中分散有或不溶于其中的无机碘化物微/纳米颗粒，以及可吸收聚酯中的复合无机碘化物微/纳米颗粒，聚酯 - 聚氨酯，聚酯酯 ，或聚醚 - 酯聚氨酯基质用于医疗器械和治疗组合物。
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8.发明申请RADIOPAQUE IODINATED AND IODIDE-CONTAINING CRYSTALLINE ABSORBABLE ALIPHATIC POLYMERIC MATERIALS AND APPLICATIONS THEREOF 审中-公开放射性碘化物和含碘化物的可吸收的聚氨酯材料及其应用公开(公告)号：US20160243292A1
公开(公告)日：2016-08-25
申请号：US15147712
申请日：2016-05-05
CPC分类号： A61L31/18 , A61K47/34 , A61L27/18 , A61L27/58 , A61L29/085 , A61L29/148 , A61L29/18 , A61L31/06 , A61L31/10 , A61L31/148 , C08G18/4607 , C08G18/73 , C08G63/6822 , C08G64/0233 , C09D167/04 , C09D169/00 , Y10T428/139
摘要： Radiopaque, iodinated, absorbable polyesters, polyester urethanes, and polyether-ester-urethanes with and without inorganic iodide micro-/nanoparticles dispersed or solubilized therein, and composite inorganic iodide micro-/nanoparticles in an absorbable polyester, polyester-urethane, polyester-ester, or polyether-ester urethane matrix are employed in medical devices and therapeutic compositions.
摘要翻译： 不溶性，碘化，可吸收的聚酯，聚酯氨酯和聚醚 - 酯 - 聚氨酯，其中分散有或不溶于其中的无机碘化物微/纳米颗粒，以及可吸收聚酯中的复合无机碘化物微/纳米颗粒，聚酯 - 聚氨酯，聚酯酯 ，或聚醚 - 酯聚氨酯基质用于医疗器械和治疗组合物。
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9.发明授权公开(公告)号：US08383140B2
公开(公告)日：2013-02-26
申请号：US12798457
申请日：2010-04-05
IPC分类号： A01N25/34
CPC分类号： A61K31/7036 , A01N25/34 , A61K9/0034 , A61K9/0053 , A61K31/12 , A61K31/192 , A61K31/337 , A61K31/4025 , A61K31/4164 , A61K31/4174 , A61K31/4196 , A61K31/427 , A61K31/436 , A61K31/496 , A61K31/497 , A61K31/505 , A61K31/506 , A61K31/65 , A61K47/34 , A61M25/002 , A61M25/04 , A61M25/10 , A61M31/00 , A61M31/007 , A61M2025/0024 , A61M2025/105 , B65B3/04 , B65B51/10 , B65B55/04 , B65B55/14 , B65D65/38
摘要： Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.
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10.发明申请Absorbable crystalline copolyester-based bioactive hydroforming luminal liner compositions 有权可吸收的基于结晶共聚酯的生物活性液压成型内衬衬垫组合物公开(公告)号：US20100256081A1
公开(公告)日：2010-10-07
申请号：US12798457
申请日：2010-04-05
IPC分类号： A61K31/7036 , A61K31/497 , A61K31/4174 , A61K31/506 , A61K31/427 , A61K31/4164 , A61K31/4025 , A61K31/65 , A61K31/192 , A61K31/337 , A61K31/12 , A61K31/436 , A61P31/00 , A61P29/00 , A61P35/00 , A61P37/00 , A61M31/00 , B65B55/14
CPC分类号： A61K31/7036 , A01N25/34 , A61K9/0034 , A61K9/0053 , A61K31/12 , A61K31/192 , A61K31/337 , A61K31/4025 , A61K31/4164 , A61K31/4174 , A61K31/4196 , A61K31/427 , A61K31/436 , A61K31/496 , A61K31/497 , A61K31/505 , A61K31/506 , A61K31/65 , A61K47/34 , A61M25/002 , A61M25/04 , A61M25/10 , A61M31/00 , A61M31/007 , A61M2025/0024 , A61M2025/105 , B65B3/04 , B65B51/10 , B65B55/04 , B65B55/14 , B65D65/38
摘要： Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.
摘要翻译： 生物活性的液压成型管腔内衬组合物由溶解在聚醚二醇的液体衍生物中的高分子量结晶的可吸收的共聚酯形成，所述聚醚二醇经历转变成组织粘附的弹性内盖或衬垫，用于在临床受损的情况下控制释放其生物活性有效载荷 如在细胞和酵母感染的阴道运河，食管和血管成形术后的动脉的情况下，人的管道。
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