公开(公告)号：US20210177032A1

公开(公告)日：2021-06-17

申请号：US17182676

申请日：2021-02-23

申请人： UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： Valter D. LONGO ,  Chia-Wei CHENG ,  Sebastian BRANDHORST ,  Min WEI

IPC分类号： A23L33/00 ,  A61K45/00 ,  A23L29/30 ,  A23L33/115 ,  A23L33/175 ,  A23L33/17 ,  A23L33/16 ,  A23L33/15 ,  A23L33/155

摘要： A method includes a step of identifying a subject in need of diet modification; and administering a first diet to the subject for a first time period. The first diet provides 4.5 to 7 kilocalories per pound of subject for a first day and 3 to 5 kilocalories per pound of subject per day for a second to fifth day of the first diet. The first diet includes less than 30 g of sugar on the first day; less than 20 g of sugar on the second to fifth days; less than 28 g of proteins on the first day; less than 18 g of proteins on days the second to fifth days; 20 to 30 grams of monounsaturated fats on the first day; 10 to 15 grams of monounsaturated fats on the second to fifth days; and between 6 and 10 grams of polyunsaturated fats on the first day.

公开(公告)号：US11007165B2

公开(公告)日：2021-05-18

申请号：US16784553

申请日：2020-02-07

申请人： Abbott Laboratories

发明人： Gaurav Patel ,  Tapas Das ,  Rockendra Gupta

IPC分类号： A23L33/12 ,  A61K31/20 ,  A61K9/10 ,  A61K31/202 ,  A23L33/16 ,  A23L33/17 ,  A23L33/10 ,  A23L33/00 ,  A23L33/115 ,  A23L33/125 ,  A61K31/047 ,  A61K31/19 ,  A61K33/30

摘要： Liquid nutritional compositions include functional ingredients such as beta-hydroxy-beta-methylbutyrate, docosahexaenoic acid, and lutein. The nutritional compositions are useful to promote at least one of physical performance (e.g., body composition, muscle mass, muscle strength) and cognitive function (e.g., focus, attention, alertness, executive function) in an individual. The functional ingredients are incorporated into the nutritional composition in such a way that they do not adversely affect the desirable properties of the nutritional composition such as, for example, nutritional value, stability, solubility, taste, and mouthfeel.

公开(公告)号：US20210106599A1

公开(公告)日：2021-04-15

申请号：US17004842

申请日：2020-08-27

申请人： Tate & Lyle Ingredients Americas LLC

发明人： Patricia S. Williamson ,  Ryan D. Woodyer

IPC分类号： A61K31/7004 ,  A61K31/716 ,  A23L2/60 ,  A23L33/17 ,  A23L33/125 ,  A23L33/21 ,  A61K31/7016 ,  A23L27/30 ,  A23L2/52 ,  A61K31/721 ,  A23L33/10 ,  A23L33/26 ,  A23L2/66

摘要： The present invention relates to methods for improving the gastrointestinal tolerance of food and beverage products comprising sweet, low-digestible carbohydrates, and the use of one or more of D-glucose, fiber and protein for improving the gastrointestinal tolerance of food and beverage products comprising sweet, low-digestible carbohydrates.

公开(公告)号：US20210100751A1

公开(公告)日：2021-04-08

申请号：US15733458

申请日：2019-02-01

申请人： Commonwealth Scientific and industral Research Organisation

发明人： Mary Ann AUGUSTIN ,  Luz SANGUANSRI

IPC分类号： A61K9/50 ,  A61K8/11 ,  A61K36/31 ,  A61K8/9789 ,  A61K8/60 ,  A61K31/7028 ,  A61K36/88 ,  A61K8/9794 ,  A61K31/353 ,  A61K8/49 ,  A61K31/105 ,  A61K31/202 ,  A61K8/36 ,  A61K8/92 ,  A61K35/60 ,  A61K8/04 ,  A61K8/06 ,  A61K9/107 ,  A61K9/00 ,  A61K8/46 ,  A61K31/26 ,  A61K8/02 ,  A61K9/19 ,  A61K9/20 ,  A23D7/005 ,  A23D7/02 ,  A23D7/01 ,  A23L19/00 ,  A23D7/06 ,  A23P10/35 ,  A23P10/28 ,  A23L33/12 ,  A23L33/17 ,  A23L33/125 ,  A23K20/158 ,  A23K20/147 ,  A23K20/163 ,  A23K50/80

摘要： The invention relates to a method of producing an emulsion or suspension from a biomass. The invention also relates to producing a powder or products produced therefrom. The invention also relates to an emulsion or suspension produced by a method as described herein. The invention also relates to a powder produced by a method as described herein or products produced therefrom.

公开(公告)号：US10792340B2

公开(公告)日：2020-10-06

申请号：US15563795

申请日：2016-04-04

申请人： KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION

发明人： Yeong Min Park ,  In Duk Jung ,  Seung Jun Lee

IPC分类号： A61K38/45 ,  A61K35/66 ,  A61K8/98 ,  A61P31/04 ,  A01N63/10 ,  A23L33/17

摘要： Provided is an antibacterial composition against carbapenem-resistant gram-negative bacteria which includes, as an active ingredient, adenylate kinase (ADK) protein derived from Mycobacterium tuberculosis. The ADK protein derived from Mycobacterium tuberculosis, according to the subject matter, has excellent antimicrobial activity against carbapenem-resistant gram-negative bacteria, and thus may be usefully used in a variety of fields as an antibacterial composition.

公开(公告)号：US10772862B2

公开(公告)日：2020-09-15

申请号：US16160237

申请日：2018-10-15

申请人： Memorial Sloan Kettering Cancer Center ,  The Trustees of Princeton University

发明人： Joshua Rabinowitz ,  Jurre Kamphorst ,  Craig Thompson ,  Justin Cross

IPC分类号： A61K31/20 ,  A61K45/06 ,  A61K31/202 ,  G01N33/574 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A23L33/17 ,  A61K31/685 ,  A61K31/66 ,  A61K36/889

摘要： Methods and compositions for treating Ras-related cancers are provided that involve targeting lipid scavenging. Methods and compositions for identifying and/or characterizing more or less responsive cancers are also provided.

公开(公告)号：US10757957B2

公开(公告)日：2020-09-01

申请号：US14698150

申请日：2015-04-28

申请人： International Dehydrated Foods, Inc.

发明人： Roger Lynn Dake ,  Stephanie Lynch ,  Rodney McFadden

IPC分类号： A23J3/00 ,  A23J3/04 ,  A23L2/66 ,  A23K50/80 ,  A23K10/20 ,  A23K50/70 ,  A23K50/75 ,  A23K50/42 ,  A23K40/10 ,  A23K40/00 ,  A23K50/50 ,  A23L33/17

摘要： This disclosure provides a highly concentrated protein composition and the processes of making the same. The compositions are shelf-stable, easy to use and have excellent nutritional values as compared to other protein products. The compositions may be prepared from animal sources, such as chickens or turkeys.

公开(公告)号：US10751362B2

公开(公告)日：2020-08-25

申请号：US15651108

申请日：2017-07-17

申请人： Metagenics, Inc.

发明人： Sara LeBrun-Blashka ,  John Troup ,  Nikhat Contractor

IPC分类号： A61K31/715 ,  A61K31/702 ,  A23L33/00 ,  A23L33/16 ,  A23L33/115 ,  A23K20/158 ,  A23L33/17 ,  A23L33/15 ,  A23L33/175 ,  A23L33/18 ,  A23K20/174 ,  A23K20/20 ,  A23K20/142 ,  A23L33/21 ,  A23L2/52 ,  A61K9/00 ,  A61K31/07 ,  A61K31/197 ,  A61K31/198 ,  A61K31/28 ,  A61K31/355 ,  A61K31/375 ,  A61K31/401 ,  A61K31/405 ,  A61K31/4172 ,  A61K31/4188 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/525 ,  A61K31/555 ,  A61K31/593 ,  A61K31/7016 ,  A61K31/714 ,  A61K33/18 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K38/16 ,  A61K45/06

摘要： Disclosed is a prebiotic composition comprising a combination of 2′fucosyllactose (2′FL) and isomaltooligosaccharide (IMO). The 2′FL and IMO are present in the prebiotic composition in a weight ratio of from 1:1 to 1:10. The prebiotic composition is effective for use in methods of preventing and/or treating a gastrointestinal (GI) condition in an animal, such as irritable bowel syndrome (IBS), inflammatory bowel disease(s) (IBD), Crohn's disease, and ulcerative colitis (UC). A foodstuff or beverage, a medical food, a nutritional composition, and a kit presentation, each including the prebiotic composition, and each suitable for use in methods of reducing or suppressing inflammation in an animalian tract, are also disclosed. A method of using the prebiotic composition to prevent and/or treat a GI condition in an animal is further disclosed. The method comprises administering the prebiotic composition to the animal.

公开(公告)号：US10744188B2

公开(公告)日：2020-08-18

申请号：US15958308

申请日：2018-04-20

申请人： Waitaki Biosciences

发明人： Craig Lachlan McIntosh ,  Susan Finderup ,  Harold Garthwaite

IPC分类号： A61K38/39 ,  A23L33/16 ,  A23L33/17 ,  A61K9/14 ,  A61K33/42 ,  A61K35/32

摘要： An improved manufacturing process produces microcrystalline hydroxyapatite with sustained gradual calcium release that avoids spiking in blood calcium levels. Although the improved material did not cause significant elevation of blood calcium, it was just as effective in promoting bone mineralization as conventional calcium supplements. In addition, the material has much higher levels of bone growth factors as compared to prior hydroxyapatite products.

公开(公告)号：US20200230094A1

公开(公告)日：2020-07-23

申请号：US16345880

申请日：2017-10-30

申请人： The Cleveland Clinic Foundation

发明人： John Kirwan ,  Suzy Comhair ,  Kewal Asosingh

IPC分类号： A61K31/20 ,  A61K9/00 ,  A61P11/06 ,  A23L33/12 ,  A23L33/17 ,  A23L33/125 ,  A23L27/00 ,  A23D9/00 ,  A23L33/00 ,  G16H20/60 ,  G06Q10/08 ,  G06Q30/06 ,  G06Q30/00 ,  G06Q10/10 ,  G16H20/13 ,  G16H20/17

摘要： Provided herein are compositions, articles of manufacture, food products, and methods for treating certain conditions, such as fibrotic disease (e.g., asthma). For example, in certain embodiments, provided herein are food products (e.g., that are ketogenic) that contain high levels (e.g., at least 10% by weight of the food product) of capric acid (C10), myristic acid (C14), or combination thereof (e.g., as free fatty acids or as triglycerides). In other embodiments, methods are provided for receiving an order for such a food product, and shipping the food product to a subject with fibrotic disease (e.g., after receiving or verifying prescription information). In some embodiments, methods are provided of administering or providing a composition to a subject such that the subject receives at least 50 grams per day (e.g., 200 grams per day), on multiple days, of capric acid (C10), myristic acid (C14), or combination thereof.