公开(公告)号：US09615740B2

公开(公告)日：2017-04-11

申请号：US14579053

申请日：2014-12-22

Applicant: Carl Zeiss Meditec AG ,  Carl Zeiss AG

Inventor： Christoph Hauger ,  Markus Seesselberg ,  Marco Wilzbach

IPC: A61B3/14 ,  A61B3/13 ,  G02B21/00 ,  A61B3/10 ,  A61B90/20

CPC classification number: A61B3/13 ,  A61B3/102 ,  A61B3/14 ,  A61B90/20 ,  G02B21/0012

Abstract: An eye surgery microscope 1 having an illumination beam path 9 for imaging a portion of an eye 3 of a patient and a measurement beam path 25 for measuring an ametropia of the eye. The microscope comprises an objective lens 11 having an objective plane 13 in which the eye of the patient is disposable; at least one ocular 17 or a camera 19 for generating and detecting an image of the object plane, respectively; a measurement light source for generating a measurement light beam 29; a measurement module 41 having a light detector; optics traversed by the measurement beam path for directing the measurement light beam onto the retina 7 of the eye of the patient and for providing measurement light 39 reflected at the retina to the measurement module; and a controller; wherein the measurement module and the controller are configured to determine a position of an image of the retina generated by the optics along the measurement beam path and to output a measurement value representing the ametropia of the eye of the patient.

公开(公告)号：US09615028B2

公开(公告)日：2017-04-04

申请号：US15177492

申请日：2016-06-09

Applicant: Sony Corporation

Inventor： Yoichi Mizutani ,  Shigeatsu Yoshioka ,  Yoshihiro Wakita ,  Masashi Kimoto ,  Naoki Tagami

IPC: G06K9/00 ,  H04N5/232 ,  G06F19/00 ,  G06T11/00 ,  G06T7/00 ,  G06T11/60 ,  G06F3/14

CPC classification number: G06T7/0012 ,  A61B5/0059 ,  A61B90/20 ,  G06F3/14 ,  G06F19/00 ,  G06F19/321 ,  G06T11/00 ,  G06T11/60 ,  G06T2207/10056 ,  G06T2207/30024 ,  H04N5/23293

Abstract: A method of displaying a pathological microscopic image is provided. The method includes causing a display device to display a first area and a second area of a microscopic image, wherein the first area of the microscopic image is configured to be displayed in a first resolution and the second area of the microscopic image is configured to be displayed in a second resolution, and wherein the first resolution is lower than the second resolution; and causing the display device to display a first part of the first area in a first color different from an intrinsic color of the microscopic image, wherein the first part of the first area corresponds to the second area of the microscopic image, and wherein the first color includes one or more colors. An information processing apparatus, a non-transitory computer-readable medium, and an information processing system are also provided.

公开(公告)号：US20170086675A1

公开(公告)日：2017-03-30

申请号：US15128152

申请日：2015-03-25

Applicant: THE JOHNS HOPKINS UNIVERSITY

Inventor： Xingde Li ,  Alfredo Quinones-Hinojosa ,  Elliot McVeigh ,  Kaisorn Chaichana ,  Carmen Kut ,  Jiefeng Xi

IPC: A61B5/00 ,  A61B90/20

CPC classification number: A61B5/0073 ,  A61B5/00 ,  A61B5/0066 ,  A61B5/0086 ,  A61B5/7425 ,  A61B90/20 ,  A61B2090/3735

Abstract: The present invention is directed to a method for real-time characterization of spatially-resolved tissue optical properties using OCT/LCI. Imaging data are acquired, processed, displayed and stored in real-time. The resultant tissue optical properties are then used to determine the diagnostic threshold and to determine the OCT/LCI detection sensitivity and specificity. Color-coded optical property maps are constructed to provide direct visual cues for surgeons to differentiate tumor versus non-tumor tissue. These optical property maps can be overlaid with the structural imaging data and/or Doppler results for efficient data display. Finally, the imaging system can also be integrated with existing systems such as tracking and surgical microscopes. An aiming beam is generally provided for interventional guidance. For intraoperative use, a cap/spacer may also be provided to maintain the working distance of the probe, and also to provide biopsy capabilities. The method is usable for research and clinical diagnosis and/or interventional guidance.

公开(公告)号：US20160346047A1

公开(公告)日：2016-12-01

申请号：US15234276

申请日：2016-08-11

Applicant: TrueVision Systems, Inc.

Inventor： Ashok B. Tripathi

IPC: A61B34/20 ,  A61B90/20 ,  A61B3/13 ,  A61F9/013

CPC classification number: A61B34/20 ,  A61B3/13 ,  A61B34/10 ,  A61B34/25 ,  A61B90/20 ,  A61B90/37 ,  A61B2034/107 ,  A61B2034/2057 ,  A61B2034/2065 ,  A61B2090/0807 ,  A61B2090/3612 ,  A61B2090/365 ,  A61B2090/373 ,  A61B2576/00 ,  A61F9/007 ,  A61F9/0136

Abstract: A system, method, and apparatus for guiding an astigmatism correction procedure on an eye of a patient are disclosed. An example apparatus include a photosensor configured to record a pre-operative still image of an ocular target surgical site of the patient. The apparatus also includes a real-time, multidimensional visualization module configured to produce a real-time multidimensional visualization of the ocular target surgical site during an astigmatism correction procedure. The apparatus further includes a data processor configured to determine a virtual indicium that includes data for guiding the astigmatism correction procedure. The data processor uses the pre-operative still image to align the virtual indicium with the multidimensional visualization such that the virtual indicium is rotationally accurate. The data processor then displays the multidimensional visualization of the ocular target surgical site in conjunction with the virtual indicium.

Abstract translation: 公开了一种用于在患者眼睛上引导像散矫正程序的系统，方法和装置。 示例性装置包括被配置为记录患者的眼睛目标手术部位的手术前静止图像的光电传感器。 该装置还包括实时多维可视化模块，其被配置为在散光校正过程期间产生眼睛目标手术部位的实时多维可视化。 该装置还包括数据处理器，其被配置为确定包括用于引导像散校正过程的数据的虚拟标记。 数据处理器使用术前静止图像将虚拟标记与多维可视化对准，使得虚拟标记是旋转精确的。 然后，数据处理器结合虚拟标记显示眼睛目标手术部位的多维可视化。

公开(公告)号：US09474448B2

公开(公告)日：2016-10-25

申请号：US14884543

申请日：2015-10-15

Applicant: The Board of Trustees of the Leland Stanford Junior University

Inventor： Kunal Ghosh ,  Laurie Burns ,  Abbas El Gamal ,  Mark J. Schnitzer ,  Eric Cocker ,  Tatt Wei Ho

IPC: A61B5/00 ,  G02B21/16 ,  G02B21/36 ,  G02B21/00 ,  G01N21/64 ,  G02B3/00 ,  G02B27/14 ,  G06T7/00 ,  H04N5/225 ,  H04N5/232

CPC classification number: A61B5/0071 ,  A61B5/0042 ,  A61B5/0082 ,  A61B5/489 ,  A61B90/20 ,  A61B2090/306 ,  A61B2503/40 ,  A61B2503/42 ,  A61B2562/0233 ,  A61B2562/04 ,  A61B2576/026 ,  G01N21/6458 ,  G02B3/0087 ,  G02B21/0008 ,  G02B21/008 ,  G02B21/16 ,  G02B21/36 ,  G02B21/361 ,  G02B21/362 ,  G02B21/365 ,  G02B27/141 ,  G06T7/0012 ,  G06T2207/30016 ,  G06T2207/30101 ,  H04N5/2254 ,  H04N5/2256 ,  H04N5/23296

Abstract: Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.

公开(公告)号：US20160295123A1

公开(公告)日：2016-10-06

申请号：US15177492

申请日：2016-06-09

Applicant: Sony Corporation

Inventor： Yoichi MIZUTANI ,  Shigeatsu YOSHIOKA ,  Yoshihiro WAKITA ,  Masashi KIMOTO ,  Naoki TAGAMI

IPC: H04N5/232 ,  G06F3/14

CPC classification number: G06T7/0012 ,  A61B5/0059 ,  A61B90/20 ,  G06F3/14 ,  G06F19/00 ,  G06F19/321 ,  G06T11/00 ,  G06T11/60 ,  G06T2207/10056 ,  G06T2207/30024 ,  H04N5/23293

Abstract: A method of displaying a pathological microscopic image is provided. The method includes causing a display device to display a first area and a second area of a microscopic image, wherein the first area of the microscopic image is configured to be displayed in a first resolution and the second area of the microscopic image is configured to be displayed in a second resolution, and wherein the first resolution is lower than the second resolution; and causing the display device to display a first part of the first area in a first color different from an intrinsic color of the microscopic image, wherein the first part of the first area corresponds to the second area of the microscopic image, and wherein the first color includes one or more colors. An information processing apparatus, a non-transitory computer-readable medium, and an information processing system are also provided.

Abstract translation: 提供显示病理学显微镜图像的方法。 所述方法包括使显示装置显示微观图像的第一区域和第二区域，其中所述显微图像的所述第一区域被配置为以第一分辨率显示，并且所述显微图像的所述第二区域被配置为 以第二分辨率显示，并且其中所述第一分辨率低于所述第二分辨率; 并且使所述显示装置以与所述显微图像的固有颜色不同的第一颜色显示所述第一区域的第一部分，其中所述第一区域的所述第一部分对应于所述显微图像的所述第二区域，并且其中所述第一区域 颜色包括一种或多种颜色。 还提供了一种信息处理装置，非暂时性计算机可读介质和信息处理系统。

公开(公告)号：US20160183782A1

公开(公告)日：2016-06-30

申请号：US14584830

申请日：2014-12-29

Applicant: NOVARTIS AG

Inventor： Lingfeng Yu ,  Vadim Shofman

IPC: A61B3/10 ,  A61B3/13 ,  A61N5/06 ,  A61B3/14 ,  A61F9/008 ,  A61B19/00 ,  A61B3/00

CPC classification number: A61B3/102 ,  A61B3/0008 ,  A61B3/1025 ,  A61B3/13 ,  A61B3/14 ,  A61B3/18 ,  A61B90/20 ,  A61F9/00821 ,  A61F9/00823 ,  A61F2009/00851 ,  A61F2009/00863 ,  A61N5/06 ,  A61N5/062

Abstract: An ophthalmic visualization system can include an ocular lens positioned between a macular contact lens coupled to a procedure eye and a surgical microscope. The ocular lens can guide a light beam through the macular contact lens and into the procedure eye, and in combination with the macular contact lens generate an intermediate image of the procedure eye at an image plane between the procedure eye and the surgical microscope. The system can include a reduction lens positioned in the optical path between the surgical microscope and the ocular lens. The reduction lens and/or ocular lens can align a focus plane of the surgical microscope with the image plane. A method of visualizing a procedure eye in an ophthalmic procedure can include positioning an ocular lens and a reduction lens between a macular contact lens and a surgical microscope; and scanning the procedure eye with a light beam.

Abstract translation: 眼科可视化系统可以包括定位在联接到手术眼的黄斑隐形眼镜和手术显微镜之间的眼透镜。 眼透镜可引导光束通过黄斑隐形眼镜进入手术眼，并与黄斑隐形眼镜组合，在手术眼和手术显微镜之间的图像平面处产生手术眼的中间图像。 该系统可以包括位于手术显微镜和眼透镜之间的光路中的减速透镜。 还原透镜和/或眼透镜可以将外科显微镜的焦平面与图像平面对准。 在眼科手术中可视化手术眼的方法可包括将眼透镜和还原透镜定位在黄斑隐形眼镜和手术显微镜之间; 并用光束扫描手术眼。

公开(公告)号：US20160183779A1

公开(公告)日：2016-06-30

申请号：US14584685

申请日：2014-12-29

Applicant: Novartis AG

Inventor： Hugang Ren ,  Lingfeng Yu

IPC: A61B3/00 ,  G02B21/22 ,  A61B19/00 ,  A61B3/14 ,  A61B3/13

CPC classification number: G02B21/22 ,  A61B3/0058 ,  A61B3/12 ,  A61B3/132 ,  A61B90/20 ,  A61B2034/2065 ,  A61B2090/365 ,  G02B21/0012

Abstract: An ophthalmic visualization system can include an imaging device configured to acquire images of a surgical field; a computing device configured to determine an area of interest based on the images; and a display device in communication with the computing device and a surgical microscope, wherein the display device is configured to provide a graphical overlay onto at least a portion of a field of view of the surgical microscope, and wherein the graphical overlay includes a magnified image of the area of interest. A method of visualizing an ophthalmic procedure can include receiving images of a surgical field acquired by an imaging device; identifying an area of interest; generating a graphical overlay including a magnified image of the area of the interest; and outputting the graphical overlay to a display device such that the graphical overlay is positioned over a field of view of a surgical microscope.

Abstract translation: 眼科可视化系统可以包括被配置为获取外科视野的图像的成像装置; 配置为基于所述图像确定感兴趣区域的计算设备; 以及与所述计算设备和手术显微镜通信的显示设备，其中所述显示设备被配置为在所述外科手术显微镜的视野的至少一部分上提供图形覆盖，并且其中所述图形覆盖物包括放大图像 的感兴趣的领域。 可视化眼科程序的方法可以包括接收由成像装置获取的外科视野的图像; 识别感兴趣的领域; 生成包括感兴趣区域的放大图像的图形叠加; 以及将所述图形覆盖物输出到显示装置，使得所述图形覆盖物位于手术显微镜的视场上。

公开(公告)号：US20160166325A1

公开(公告)日：2016-06-16

申请号：US14949816

申请日：2015-11-23

Applicant: Robin Kusch ,  Stefan Sattler ,  Stefan Schuster

Inventor： Robin Kusch ,  Stefan Sattler ,  Stefan Schuster

IPC: A61B19/00 ,  G01L5/00

CPC classification number: G01L5/0052 ,  A61B6/102 ,  A61B6/4441 ,  A61B90/06 ,  A61B90/20 ,  A61B2090/064 ,  A61B2090/065

Abstract: A medical examination, treatment, or examination and treatment device is provided. The medical examination, treatment, or examination and treatment device includes a cover panel. The cover panel includes a sensor for detecting a collision. The sensor includes a first plate mounted on the examination, treatment, or examination and treatment device, and a second plate mounted on the inside of the cover panel and spaced apart from the first plate. Spring elements are disposed between the first plate and the second plate.

Abstract translation: 提供体检，治疗或检查和治疗装置。 医疗检查，治疗或检查和治疗装置包括盖板。 盖板包括用于检测碰撞的传感器。 传感器包括安装在检查，处理或检查和处理装置上的第一板，以及安装在盖板的内部并与第一板间隔开的第二板。 弹簧元件设置在第一板和第二板之间。

公开(公告)号：US09314374B2

公开(公告)日：2016-04-19

申请号：US12727947

申请日：2010-03-19

Applicant: Alexander N. Artsyukhovich ,  Mikhail Boukhny ,  Bruno Dacquay

Inventor： Alexander N. Artsyukhovich ,  Mikhail Boukhny ,  Bruno Dacquay

IPC: A61B1/06 ,  A61F9/007 ,  A61B1/00 ,  A61B17/00

CPC classification number: A61F9/00745 ,  A61B1/00165 ,  A61B3/0008 ,  A61B90/20 ,  A61B90/30 ,  A61B2017/00154 ,  A61B2017/00194 ,  A61B2090/306 ,  A61B2090/309

Abstract: An ophthalmic illuminator is provided that includes a pulse generator to provide amplified pulses and an amplifier to amplify the current pulses to produce amplified pulses. A light source within the ophthalmic illuminator is driven by the amplified pulses so as to stroboscopically illuminate a vibrating ophthalmic surgical tool within the interior of an eye.

Abstract translation: 提供了一种眼科照明器，其包括用于提供放大脉冲的脉冲发生器和用于放大电流脉冲以产生放大脉冲的放大器。 眼睛照明器内的光源被放大的脉冲驱动，以便在眼睛内部频闪地照亮振动的眼科手术工具。