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    INFUSION FLOW INTERRUPTION METHOD AND APPARATUS
    41.
    发明申请
    INFUSION FLOW INTERRUPTION METHOD AND APPARATUS 审中-公开
    输注流中断方法和装置

    公开(公告)号：US20080161723A1

    公开(公告)日：2008-07-03

    申请号：US11850972

    申请日：2007-09-06

    Applicant: Richard Keenan ,  Jeffrey Chiou ,  Peter Rule ,  James R. Braig

    Inventor： Richard Keenan ,  Jeffrey Chiou ,  Peter Rule ,  James R. Braig

    IPC: A61B5/00 ,  A61M5/142

    CPC classification number: A61B5/4839 ,  A61B5/14532 ,  A61B5/14557 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150267 ,  A61B5/150305 ,  A61B5/150755 ,  A61B5/150786 ,  A61B5/150824 ,  A61B5/150854 ,  A61B5/153 ,  A61B5/157 ,  A61M1/3609 ,  A61M5/14 ,  A61M5/1415 ,  A61M2005/1404 ,  A61M2005/1726 ,  A61M2230/201

    Abstract: Disclosed are systems, apparatus and methods for determining information related to analyte(s) (e.g., concentration) in a sample such as biological fluid. An analysis system for determining information relating to at least one analyte in a sample of biological fluid can be configured to: withdraw the sample of biological fluid from the source of biological fluid; interrupt the flow of infusion fluid while the sample of biological fluid is withdrawn; analyze the withdrawn biological fluid to determine information relating to at least one analyte; and resume the flow of infusion fluid after the sample of biological fluid is withdrawn. A method of interrupting flow of an infusion fluid without triggering an alarm can comprise, while the flow of the infusion fluid is interrupted, diverting the flow of the infusion fluid from a fluid passageway to an expandable volume at a rate that maintains constant flow from an infusion pump.

    Abstract translation: 公开了用于确定样品（例如生物流体）中与分析物（例如浓度）相关的信息的系统，装置和方法。 用于确定与生物流体样品中的至少一种分析物相关的信息的分析系统可以被配置为：从生物流体源中抽出生物流体的样品; 中断生物流体样本取出时输液的流动; 分析所抽取的生物流体以确定与至少一种分析物有关的信息; 并在取出生物流体的样品后恢复输注液的流动。 一种在不触发报警的情况下中断输注流体的流动的方法可以包括在输注流体的流动被中断的同时将输注流体的流动从流体通道转移到可膨胀体积，其速率保持恒定的流量 输液泵。

    Analyte detection system for multiple analytes
    43.
    发明申请
    Analyte detection system for multiple analytes 有权
    多种分析物的分析物检测系统

    公开(公告)号：US20060189858A1

    公开(公告)日：2006-08-24

    申请号：US11314176

    申请日：2005-12-21

    Applicant: Bernhard Sterling ,  James Braig ,  Kenneth Witte ,  Peter Rule ,  Richard Keenan ,  W. Hall

    Inventor： Bernhard Sterling ,  James Braig ,  Kenneth Witte ,  Peter Rule ,  Richard Keenan ,  W. Hall

    IPC: A61B5/00 ,  A61M31/00

    CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14557 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61M5/14212 ,  A61M5/14232 ,  A61M5/16854 ,  A61M2205/12 ,  A61M2230/20 ,  A61M2230/201 ,  G01N1/14 ,  G01N21/05 ,  G01N21/274 ,  G01N21/35 ,  G01N2021/0346

    Abstract: An apparatus for analyzing the composition of bodily fluid. The apparatus comprises a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient; and a pump unit in operative engagement with the fluid handling network. The pump unit has an infusion mode in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus further comprises a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample. In one implementation, the pump unit comprises a first pump operable in the infusion mode but not in the sample draw mode, and a second pump operable in the sample draw mode but not in the infusion mode.

    Abstract translation: 一种用于分析体液组成的装置。 该装置包括流体处理网络，其包括被配置为保持患者体内与体液的流体连通的患者端; 以及与所述流体处理网络操作地接合的泵单元。 泵单元具有输注模式，其中泵单元可操作以通过患者端向患者输送输注流体，以及抽样模式，其中泵单元可操作以从患者抽取体液样本，通过 病人结束 所述设备还包括定位成分析样品的至少一部分的光谱分析仪; 与光谱分析仪通信或并入其中的处理器; 以及可由处理器执行的存储的程序指令，以获得样本的两个或多个属性的测量。 在一个实施方案中，泵单元包括可在输液模式中操作但不在样品抽取模式中的第一泵，以及可在样品抽取模式中操作但不在输注模式中的第二泵。

    External ultrasonic therapy
    44.
    发明申请
    External ultrasonic therapy 审中-公开
    外部超声波治疗

    公开(公告)号：US20060184070A1

    公开(公告)日：2006-08-17

    申请号：US11272022

    申请日：2005-11-11

    Applicant: Douglas Hansmann ,  Peter Rule

    Inventor： Douglas Hansmann ,  Peter Rule

    IPC: A61H1/00 ,  A61B8/12

    CPC classification number: A61N7/00 ,  A61B2017/2253

    Abstract: A coupling pad can be used with a transducer element. Ultrasound produced by the transducer element can be propagated through the coupling pad to a patient. In one arrangement, the pad is a pouch containing a pliant substance. In other arrangements, the pad is a somewhat solid member formed of a material that transmits ultrasound waves efficiently. The pad may be configured to fit between a patient's skin and a transducer element so that output from the transducer element passes through the pad to a treatment site of the patient.

    Abstract translation: 耦合垫可以与换能器元件一起使用。 由换能器元件产生的超声能够通过耦合垫传播到患者身上。 在一种布置中，垫是包含柔韧物质的袋。 在其他布置中，垫是由有效地发射超声波的材料形成的稍微实心的部件。 垫可以被配置成适合于患者皮肤和换能器元件之间，使得来自换能器元件的输出通过垫穿过患者的治疗部位。

    Treatment of vascular occlusions using elevated temperatures
    48.
    发明申请
    Treatment of vascular occlusions using elevated temperatures 有权
    使用升高的温度治疗血管闭塞

    公开(公告)号：US20050240151A1

    公开(公告)日：2005-10-27

    申请号：US11046209

    申请日：2005-01-28

    Applicant: Douglas Hansmann ,  Peter Rule

    Inventor： Douglas Hansmann ,  Peter Rule

    IPC: A61B17/22 ,  A61B18/04 ,  A61F7/12

    CPC classification number: A61B17/2202 ,  A61B2018/046

    Abstract: A method for providing a therapeutic effect to a treatment site within a patient's vasculature comprises positioning a catheter at the treatment site. The catheter includes a heating element and a fluid delivery lumen that is coupled to an exit port within a distal region of the catheter. The method further comprises passing the therapeutic compound through the delivery lumen and the exit port at a flow rate. The heated therapeutic compound is provided to the treatment site. The method further comprises exposing at least a portion of the treatment site and at least a portion of the delivered heated therapeutic compound to ultrasonic energy generated by the ultrasound radiating member.

    Abstract translation: 用于向患者的脉管系统内的治疗部位提供治疗效果的方法包括将导管定位在治疗部位。 导管包括加热元件和流体输送腔，其与导管的远侧区域内的出口连接。 该方法还包括以流速使治疗化合物通过输送腔和出口。 将加热的治疗化合物提供给治疗部位。 所述方法还包括将所述处理部位的至少一部分和所递送的加热治疗化合物的至少一部分暴露于由所述超声波辐射部件产生的超声波能量。

    Sample element qualification
    50.
    发明申请
    Sample element qualification 审中-公开
    样品单元鉴定

    公开(公告)号：US20050036146A1

    公开(公告)日：2005-02-17

    申请号：US10824933

    申请日：2004-04-15

    Applicant: James Braig ,  Kenneth Witte ,  Philip Hartstein ,  Ken Li ,  Peter Rule

    Inventor： James Braig ,  Kenneth Witte ,  Philip Hartstein ,  Ken Li ,  Peter Rule

    IPC: G01N21/03 ,  G01N21/59 ,  G01N21/86 ,  G01N35/00 ,  G01N21/00

    CPC classification number: G01N35/00732 ,  G01N21/03 ,  G01N21/5907 ,  G01N21/8483 ,  G01N2035/00752 ,  G01N2035/00762 ,  G01N2035/00772 ,  G01N2035/00782

    Abstract: A sample element includes first and second substantially parallel faces separated by an intermediate member. The parallel faces and the intermediate member at least partially define a sample chamber configured to hold a volume of fluid. The sample element further includes an optical path extending through the parallel faces and the intermediate member, such that electromagnetic radiation can propagate through the sample chamber. The sample element further includes an identifying compound disposed within or on at least one of the parallel faces. The identifying compound has at least one indexed optical absorbance feature, such that spectral analysis of electromagnetic radiation propagated through the sample chamber yields the indexed optical absorbance feature. Detection of the indexed optical absorbance feature in electromagnetic radiation propagated through the sample chamber indicates to an analyte detection system whether the sample element is configured for use with the analyte detection system.

    Abstract translation: 样品元件包括由中间构件分隔开的第一和第二基本上平行的面。 平行面和中间构件至少部分地限定了构造成保持一定体积的流体的样品室。 样本元件还包括延伸穿过平行面和中间构件的光路，使得电磁辐射可以传播通过样品室。 样本元件还包括设置在至少一个平行面内或之中的识别化合物。 识别化合物具有至少一个索引的光吸收特征，使得通过样品室传播的电磁辐射的光谱分析产生索引的光吸收特征。 通过样品室传播的电磁辐射中的指示光吸收特征的检测表明分析物检测系统是否将样品元件配置为与分析物检测系统一起使用。

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